RT Journal Article A1 Liu, Hongting A1 Bittencourt, Millena G. A1 Wang, Jiangxia A1 Sophie, Raafay A1 Annam, Rachel A1 Ibrahim, Mohamed A. A1 Sepah, Yasir J. A1 Moradi, Ahmadreza A1 Scholl, Hendrik P. N. A1 Nguyen, Quan Dong T1 Assessment of Central Retinal Sensitivity Employing Two Types of Microperimetry Devices JF Translational Vision Science & Technology JO Trans. Vis. Sci. Tech. YR 2014 DO 10.1167/tvst.3.5.3 VO 3 IS 5 SP 3 OP 3 SN 2164-2591 AB To compare the retinal sensitivity measurements obtained with two microperimeters, the Micro-Perimeter 1 (MP-1) and the Optos optical coherence tomography (OCT)/scanning laser ophthalmoscope (SLO) in subjects with and without maculopathies. Forty-five eyes with no known ocular disease and 47 eyes with maculopathies were examined using both microperimeters. A contrast-adjusted scale was applied to resolve the different stimuli and background luminance existing between the two devices. There was a strong ceiling effect with the MP-1 in the healthy group, with 90.1% (1136 of 1260) test points clustered at 20 dB. The mean sensitivity for the corresponding points in the OCT/SLO was 25.8 ± 1.9 dB. A floor effect was also observed with the OCT/SLO in the maculopathy group with 9.7% (128 of 1316) points clustered at 9-dB values. The corresponding mean sensitivity in the MP-1 was 1.7 ± 3.9 dB. A regression equation between the two microperimeters was established in the common 10 to19 dB intervals as: OCT/SLO = 15.6 + 0.564 × MP-1 − 0.009 × MP-12 + k (k is an individual point constant; MP-1 coefficient P < 0.001; MP-12 coefficient P = 0.006). The OCT/SLO and the MP-1 provide two different ranges of contrasts for microperimetry examination. Broadening the dynamic range may minimize the constraint of the ceiling and floor effect. There is a significant mathematical relationship in the common interval of the contrast scale. Applying a unified and broadened dynamic range in different types of microperimeters will help to generate consistent clinical reference for measurements. RD 3/7/2021 UL https://doi.org/10.1167/tvst.3.5.3