RT Journal Article
A1 Liu, Hongting
A1 Bittencourt, Millena G.
A1 Wang, Jiangxia
A1 Sophie, Raafay
A1 Annam, Rachel
A1 Ibrahim, Mohamed A.
A1 Sepah, Yasir J.
A1 Moradi, Ahmadreza
A1 Scholl, Hendrik P. N.
A1 Nguyen, Quan Dong
T1 Assessment of Central Retinal Sensitivity Employing Two Types of Microperimetry Devices
JF Translational Vision Science & Technology
JO TVST
YR 2014
DO 10.1167/tvst.3.5.3
JF Translational Vision Science & Technology
VO 3
IS 5
SP 3
OP 3
SN 2164-2591
AB    To compare the retinal sensitivity measurements obtained with two microperimeters, the Micro-Perimeter 1 (MP-1) and the Optos optical coherence tomography (OCT)/scanning laser ophthalmoscope (SLO) in subjects with and without maculopathies.    Forty-five eyes with no known ocular disease and 47 eyes with maculopathies were examined using both microperimeters. A contrast-adjusted scale was applied to resolve the different stimuli and background luminance existing between the two devices.    There was a strong ceiling effect with the MP-1 in the healthy group, with 90.1% (1136 of 1260) test points clustered at 20 dB. The mean sensitivity for the corresponding points in the OCT/SLO was 25.8 ± 1.9 dB. A floor effect was also observed with the OCT/SLO in the maculopathy group with 9.7% (128 of 1316) points clustered at 9-dB values. The corresponding mean sensitivity in the MP-1 was 1.7 ± 3.9 dB. A regression equation between the two microperimeters was established in the common 10 to19 dB intervals as: OCT/SLO = 15.6 + 0.564 × MP-1 − 0.009 × MP-12 + k (k is an individual point constant; MP-1 coefficient P < 0.001; MP-12 coefficient P = 0.006).    The OCT/SLO and the MP-1 provide two different ranges of contrasts for microperimetry examination. Broadening the dynamic range may minimize the constraint of the ceiling and floor effect. There is a significant mathematical relationship in the common interval of the contrast scale.    Applying a unified and broadened dynamic range in different types of microperimeters will help to generate consistent clinical reference for measurements.  
RD 10/15/2019
UL https://doi.org/10.1167/tvst.3.5.3