Abstract
Purpose::
While prisms are commonly prescribed for homonymous hemianopia to extend or expand the visual field, they cause potentially troubling visual side effects, including nonveridical location of perceived images, diplopia, and visual confusion. In addition, the field behind a prism at its apex is lost to an apical scotoma equal in magnitude to the amount of prism shift. The perceptual consequences of apical scotomas and the other effects of various designs were examined to consider parameters and designs that can mitigate the impact of these effects.
Methods::
Various configurations of sector and peripheral prisms were analyzed, in various directions of gaze, and their visual effects were illustrated using simulated perimetry. A novel “percept” diagram was developed that yielded insights into the patient's view through the prisms. The predictions were verified perimetrically with patients.
Results::
The diagrams distinguish between potentially beneficial field expansion via visual confusion and the pericentrally disturbing and useless effect of diplopia, and their relationship to prism power and gaze direction. They also illustrate the nonexpanding substitution of field segments of some popular prism designs.
Conclusions::
Yoked sector prisms have no effect at primary gaze or when gaze is directed toward the seeing hemifield, and they introduce pericentral field loss when gaze is shifted into them. When fitted unilaterally, sector prisms also have an effect only when the gaze is directed into the prism and may cause a pericentral scotoma and/or central diplopia. Peripheral prisms are effective at essentially all gaze angles. Since gaze is not directed into them, they avoid problematic pericentral effects. We derive useful recommendations for prism power and position parameters, including novel ways of fitting prisms asymmetrically.
Translational Relevance::
Clinicians will find these novel diagrams, diagramming techniques, and analyses valuable when prescribing prismatic aids for hemianopia and when designing new prism devices for patients with various types of field loss.
Homonymous hemianopia (HH), the loss of half the visual field in both eyes on the same side and to similar extent, results from postchiasmatic lesions typically caused by stroke, tumor, or trauma.
1 Hemianopic visual field loss reduces detection of objects in the blind hemifield and impacts the ability to avoid obstacles while walking and driving.
2–4
Spectacle-mounted prisms are the most commonly used rehabilitation devices for HH. There are various designs and methods for fitting prism spectacles. All involve tradeoffs between the access to otherwise invisible areas of the visual scene and the various potentially troubling visual side effects the prisms introduce. While the prism apical scotoma has been mentioned in the literature,
5–9 its functional significance has not been addressed, nor has its impact on the residual visual field been illustrated. This paper examines common prism configurations used for HH, and primarily analyzes the oft-ignored, but important, effect of prism apical scotomas. Other effects, such as the diplopia and visual confusion induced in some configurations and the nonveridical views created by all designs are also addressed, and their impact is illustrated in a novel way. Careful fitting design based on the parameters and diagrams provided here can mitigate these effects. The analyses will also provide practitioners insights into why some configurations may be accepted and valued more than others by their patients. Novel designs emerged from these analyses, described in the sections on offset sector and peripheral prism placement.
The bending of light rays by a prism creates a gap in the visible field of view between the last undeviated ray just outside the prism, at its apex, and the first ray deviated by the prism.
5 The angular extent of that gap is equal to the prism power in degrees (
Fig. 1A). That gap is referred to as the
apical scotoma. The perceived (retinal) field of view is still fully covered by rays from portions of the external field, but the view from within the scotoma is missing, obscured by the prism itself. Thus, this “scotoma” is a gap in the portion of the external world view that is seen, not a blind retinal area. The retinal image is discontinuous, but has no blanks. (If a prism is replaced by an opaque occluder, visual field equal in width to the visual angle the occluder subtends would be lost behind the occluder. With a prism, the field blocked by the prism beyond the apical scotoma is seen at the prism apex; hence, the apical scotoma is the only loss.) The effect is illustrated photographically by holding a prism in front of a camera lens (
Fig. 1B).
All of the prism configurations to be discussed cause portions of the world view to appear in nonveridical directions; the apparent location through the prism is displaced from the true direction (e.g., the lower portion of the lamppost in
Fig. 1B).
When prisms are placed bilaterally for HH, with essentially the same position and coverage for each eye, the prism apical scotomas induce a gap in the visual field. When placed monocularly (or at different relative positions on each carrier lens), it is possible for the view of one eye to include field portions missing to the apical scotoma of the fellow eye. These configurations produce areas of visual confusion, in which two different views are seen at the same apparent direction by the two eyes, and some produce diplopia, wherein a given object or portion of the scene is seen in two different directions simultaneously. We avoid using the term “double vision,” as it has been ambiguously applied in the literature to include or exclude confusion and diplopia.
If the total field
area available (at a given direction of gaze) is larger than the hemifield available without prisms, we deem this to be true field
expansion. Semitransparent mirrors have been used to provide true expansion,
10 but they are bulky, unsightly, and add the disorientation of a reversed view to the visual confusion. They are now rarely used and are not discussed further here. As will be seen below, true expansion is possible with prisms, but only if they are fit asymmetrically, or monocularly, so that different portions of the field are available to each eye (albeit with some visual confusion).
Most bilateral prism designs provide field substitution rather than expansion: The total area visible at any time is no greater than without prisms; the area shifted into view displaces an equal amount of the unaided view, creating an optical scotoma in the field—the apical scotoma. We also avoid the term “field enhancement”, as it is ambiguous with respect to these important distinctions.
If prisms cover the entire field of view (as happens with bilateral full-field yoked prisms
6,9,11 ), field
shifting, without expansion or substitution, occurs. Field shifting is of no value for patients with HH, as normal fixation, head, and eye movements will negate it to bring the view straight ahead into primary gaze. The prism configurations discussed here (sector and peripheral prisms) do not span the full field horizontally, so the placement of the prism apices becomes a critical design element, affecting the role the apical scotomas play in the patient's experience, as well as the location of regions of visual confusion and diplopia. (The prism bases are set far into the blind side, where they are rarely in view.) Visual confusion is a necessary consequence of prismatic field expansion. It is more readily tolerated in the periphery than in central vision. Confusion and diplopia are very disturbing centrally (parafoveally), while they are normal in the periphery.
12 Prism-induced diplopia anywhere, however, represents a waste of prism power that could be better used for expansion (or substitution), as will become apparent below.
In the subsequent sections, we identify the parameters that affect optimal positioning and power for each of the common methods of fitting prisms, and discuss their implications in terms of field expansion or substitution and troublesome perceptual effects including apical scotomas, diplopia, and visual confusion. Often confusion and diplopia are thought to coexist, but these analyses make clear how independent these phenomena can be. The examples are illustrated using predicted/calculated and actual visual field diagrams from patients, and we introduce a new visual field representation technique, the percept diagram, to describe the patient's binocular view through the prism spectacles.
If a sector prism of the type described above is fit on only one carrier lens (typically ipsilateral to the field defect; OS for a patient with left hemianopia), the nonprism eye can see some or all of the area lost to the prism eye's apical scotoma. The region between the gaze point into the prism and the prism apex is seen unblocked by the prism by the nonprism eye, and is, thus, not lost in the binocular field to the scotoma. If the angle of gaze into the prism is less than the prism power, some scotoma will remain. If the angle of gaze into the prism is larger, there is an area of diplopia equal in width to the excess of the gaze angle beyond the prism power. In this and subsequent discussions, we assume that the patient is orthophoric. Because the unilateral prism can dissociate binocularity, the actual binocular field results may vary with patient's phoria and eye dominance. Note, in this unilateral sector design too, the prism has no effect in primary position of gaze or when the patient gazes towards the sighted hemifield.
Figure 7 builds the percept diagram for the case in which the gaze angle into the prism is larger than the prism power. The fitting parameters are as above (gazing 20° into a 20Δ prism offset 6° from primary gaze). The fellow eye now sees the region lost to the apical scotoma of the prism eye, although there is visual confusion in that area and a 9° wide area of diplopia. Confusion and diplopia around the gaze point can make it difficult for the patient to quickly interpret the view, and may result in suppression; thus, eye dominance and the overall binocular status of the patient may be important factors.
Figure 8A is the computed Goldmann visual field diagram analogous to
Figure 5A, with the patient facing straight at the fixation light and gaze shifted 20° into the prism.
Figure 8C gives the calculated diagram analogous to
Figure 5C, with the head rotated 26° right, so that the left eye is gazing 20° into the prism when the right eye is gazing at the fixation target.
Figure 8D gives the actual patient results under that condition. As noted above, the calculated diagrams are created as if the nodal points of both eyes are at the perimeter origin; clearly impossible to actually achieve. However, in the mobility situations where these diagrams are relevant, the distance to the targets of interest are so large that the distance between the eyes is inconsequential.
Figures 8E through
8H are the corresponding diagrams when gaze is shifted just 5° into the prism, where the amount of eye movement in degrees is less than the amount of prismatic shift. For a 5° gaze shift into the prism segment (total 6° + 5° = 11° shift from primary gaze), there is no diplopia, but the apical scotoma is present in the binocular view, as the nonprism eye sees only 5° of the 11° apical scotoma region, and that part is seen with visual confusion.
Thus, the unilateral sector prism design can reduce or eliminate the apical scotoma and provide some true binocular field expansion, not just substitution. However, the apical scotoma does appear in the binocular view as the eye crosses the prism segment, until the amount of gaze shift is equivalent to or greater than the prism power in degrees. Furthermore, central and peripheral field confusion around the gaze point do occur, and as the gaze is shifted farther into the prism, central and peripheral diplopia ensue. The percept diagram shows these effects. Since this is the first example with confusion and diplopia,
Figure 7 builds the diagram a step at a time, so the component effects are clearer. Subsequent diagrams will only show the compounded final effect. To best represent the situation the patient experiences, we do not use color to distinguish the OD and OS contributions to visual confusion. However, where this may be particularly hard for the reader to interpret, we have also provided magnified detail views with color. Nonetheless, since the perceived location of prism-induced diplopia is not readily identified in the Goldmann diagrams, we highlight it in the percept diagrams, even though that delineation, of course, is not apparent to the patient.
The Gottlieb prism design
32 differs from unilateral sector prisms, in that only a circular cutout of the sector prism is used. The prism apex is placed at the limbus, and is, thus, offset by about 6 mm (~13° = tan
−1[6/(
CR+
BVD)]), which is a larger angle than 97% of natural saccades.
28,29 The prism is intended to be used during brief glances to aid in locating objects of interest. Its smaller size makes it lighter weight and perhaps less conspicuous (better cosmetics), losing some peripheral areas of a full sector prism that are arguably less important. The main optical effects, however, are identical to those of a unilateral sector prism within the coverage area of the Gottlieb prism.
The bases of horizontal peripheral prisms are placed toward the blind hemifield to provide field access to areas in the blind hemifield horizontally in line with the prisms. (Like the sector prisms, the apex-base axis is horizontal, parallel to the 180° meridian.) Prisms of 40Δ and 57Δ provide shifts of 22° and 30°, respectively, and prisms can be fit unilaterally or bilaterally. While it is preferable to fit patients with the 57Δ peripheral prisms, as they provide more field expansion, press-on temporary prisms are only available up to 40Δ. Thus, 40Δ press-on Fresnel prisms (available precut to the same size as permanent prisms) are recommended for initial prescription by the clinician on a trial basis before prescribing higher-powered permanent Fresnel prisms. Higher prism powers have correspondingly larger apical scotomas, but as shown below for unilateral fitting, that can be turned into an advantage.
An apex-base angle of about 30° provides a good compromise between vertical shift and the resulting loss of some horizontal expansion. An oblique prism of 57Δ and 30° tilt provides 26° of horizontal shift and 15° vertical shift.
Figure 16 diagrams the effects of this configuration.
Supplementary Figure S3 has diagrams illustrating the effects of the same design with gazes to the right and left, and
Supplementary Figure S4 has the corresponding diagrams for 40Δ prisms.
Thus, unilateral oblique peripheral prisms provide awareness of areas closer to the horizontal meridian, as might benefit a driver. Unlike sector prisms, they do this without actually impinging on the pericentral region and, thus, maintain binocular foveal fusion and avoid central confusion. With unilateral fitting there is peripheral confusion, but apical scotomas are avoided in the binocular field. With the bland design of most visors and dashboards, the outside road view on the blind side, with its dynamic nature, is likely to predominate under this rivalrous condition.
Prisms are often prescribed to provide access to portions of the field of view lost to hemianopia. Failure to consider the pericentral view that is lost to prism apical scotomas can lead to deficits potentially more harmful than those the prisms are intended to resolve, yet reports of prism use frequently include discussions or diagrams that omit these scotomas.
18,21,43–45 If the fellow eye does not have a scotoma in the same location, the effect can be mitigated. Unilateral fitting, or bilateral fitting of prisms offset so that their apical scotomas block different portions of the binocular visual field, can accomplish that, albeit by introducing regions of visual confusion and possibly also creating diplopia.
Visual confusion and diplopia are particularly objectionable if in central or pericentral view, while they are well tolerated in the periphery, where in some sense they are normal. Visual confusion is the mechanism by which field expansion with prisms is made possible. Without confusion, prisms can only shift the view, trading one scotomatous location with another. Diplopia, on the other hand, has no beneficial effect in these treatments and should be avoided or reduced when possible. Direct foveation through prisms reduces acuity and contrast sensitivity and introduces other disturbing and noticeable spatial and chromatic distortions. Peripherally-placed prisms are much less disturbing in these regards, and yet are effective in attracting attention that can cause the wearer to shift gaze centrally to the alerted direction, similar to the natural role of peripheral vision.
These observations lead us to conclude that traditional sector prisms, which provide no field substitution or expansion at primary gaze and induce central and pericentral scotomas when the gaze is shifted into them, are of questionable value. The claim that they serve to train the users to fixate in their direction
7,46 has not been supported with any documentation. The peripheral prisms developed in our lab avoid those shortcomings and have been met with considerable patient acceptance. They have been found useful in single and multicenter clinical trials, both open label
34 and randomized controlled.
38,39 The peripheral prisms provide true field expansion at most horizontal gaze directions, including primary. Although operating in the periphery, the oblique design can provide pericentral field expansion. This effect is particularly important for patients who are permitted to drive. The prisms access important regions of the road view, while the confusion in unilateral fit and apical scotomas in bilateral fit fall in the bland interior of the car and thus are less likely to be deleterious. Although the peripheral prisms are generally fit unilaterally, as this is easier and less expensive, offset bilateral fitting provides another option for dealing with the apical scotomas. Oblique bilateral fitting may prove more beneficial for driving than unilateral fitting.
Despite the long history of sector prisms, we found only three controlled sector prism trials,
18,32,47 and each had limitations. Rossi et al.
18 used a parallel arm trial to evaluate bilateral 15Δ sector prisms against a no treatment control in patients undergoing an inpatient stroke rehabilitation program. The study (which found no advantage for the prisms in activities of daily living) recruited patients with either HH or spatial neglect (without HH) during the acute post stroke period, in which spontaneous recovery in neglect and visual field is common. Much of the improvement in the treatment group occurred on spatial neglect tests. However, the way sector prisms may be affecting neglect is not known and beyond the scope of this paper. “Expansion” occurred in both the treatment and control groups and did not include measurements in the seeing hemifield where the apical scotomas lay. As the prisms were fitted 2 mm into the blind hemifield, they should have had no effect on the perimetry results; thus, the improvements recorded were most likely due to spontaneous recovery. Gottlieb et al.
32 evaluated their unilateral 18.5Δ sector prisms against a control device, which appeared similar, but included a “plano lens without prism power.” Methodology was not well described, but all subjects tried the real prisms before the shams. They reported increased “awareness” of the visual field ranging from 10° to 45° in binocular (but not monocular) viewing with the real prisms; however, a 45° increase in visual field from a 10.5° prism is physically impossible. Szlyk et al.,
47 used a counterbalanced crossover trial to evaluate the Gottlieb unilateral 18.5Δ ophthalmic sector prisms against similarly shaped and positioned press-on 20Δ Fresnel prisms. The aim was to evaluate the relative efficacy of the two types of prisms when combined with an intensive 3-month training program. Unsurprisingly, improvements in performance on a wide range of tests were similar for the two prism types, as they had similar prismatic powers and differed only in optical quality and cosmetics. Unfortunately, the study design did not permit an evaluation of the benefits of the prisms alone (without training) relative to no prisms. The importance of including a sham control treatment in detecting placebo effects was highlighted in our clinical trial of real versus sham peripheral prisms
38 in which 26% of subjects selected the sham control over no glasses or the real prisms.
The limitations in the clinical trials of sector prisms do not strengthen or weaken our comparison with peripheral prisms, as our arguments against sector prisms are based upon the physics of the configurations. Peripheral prisms were developed and refined specifically to address the shortcomings of sector prisms. The theoretical benefits of the design have now withstood verification in clinical, single and multicenter, and randomized controlled trials, and their continued use by about 50% of patients after 12 months is a strong result for a low vision rehabilitation aid.
Attention to the principles and diagrams we provided can avoid prescription mistakes. Moving peripheral prisms temporally will not increase their effect; rather it exacerbates the apical scotoma effects and wastes much of the prism extent where it is not likely to be used, robbing it from where it does provide benefit. Similarly, increasing the power of sector prisms increases the region lost to the apical scotomas, requiring even larger gaze shifts for pericentral views into the blind hemifield.
Our analyses and illustrations of the effects of apical scotomas have yielded subtle insights into the many ways prisms can both aid and hinder vision. Conventional wisdom and our own intuition were proved wrong or incomplete on numerous occasions by this analysis and diagramming.
Supported by the National Institutes of Health Grants EY12890 and P30EY003790.
Aspects of this study have been presented as: Ross NC, et al. IOVS. 2009;50:ARVO E-Abstract 4734.
Disclosure: H.L. Apfelbaum, None; N.C. Ross, None; A.R. Bowers, None; E. Peli, Schepens Eye Research Institute to Chadwick Optical (P)