Vitreous humor (approximately 50 µL at each in-life time point; approximately 150 µL at termination) was sampled at baseline, months 3, 7, 9, 13, 15.5, 19, and 21 for animals A055, A075, A194, A118, and K938; at baseline and months 3, 7, 9, 13, 15.5, and 19 for animal A070; and at months 1, 2, 3, 6, 12, 15, 20, 22, 26, 28, and 30 for animal K700. Aqueous humor (approximately 50 µL at each time point) was sampled at baseline and months 7 and 16, and 21 for animals A055, A070, A194, A118, and K938; at baseline and months 7, 16, and 19 for animal A075; and at baseline and months 1, 2, 3, 6, 12, 20, 23, 26, 28, and 30 for animal K700. Samples were collected using a 0.3-mL insulin syringe with a 27G needle introduced aseptically 3 mm posterior to the limbus.