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Jack Phu, Michael Kalloniatis; The Frontloading Fields Study: The Impact of False Positives and Seeding Point Errors on Visual Field Reliability When Using SITA-Faster. Trans. Vis. Sci. Tech. 2022;11(2):20. doi: https://doi.org/10.1167/tvst.11.2.20.
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© ARVO (1962-2015); The Authors (2016-present)
The purpose of this study was to evaluate the impact of two conventional reliability criteria (false positives [FPs] and seeding point errors [SPEs]) and the concurrent effect of low sensitivity points (≤19 dB) on intrasession SITA-Faster visual field (VF) result correlations.
There were 2320 intrasession SITA-Faster VF results from 1160 eyes of healthy, glaucoma suspects, and subjects with glaucoma that were separated into “both reliable” or “reliable-unreliable” pairs. VF results (mean deviation and pointwise sensitivity) were analyzed against the spectrum of FP rates and SPE, with and without censorship of sensitivity results ≤19 dB. Segmental linear regression was used to identify critical points where visual field results were significantly different between tests due to FP levels.
There was a significant, but small (0.09 dB per 1% exceeding 12%) increase in mean deviation, and an increase in the number of points showing a >3 dB sensitivity increase (0.25–0.28 locations per 1% exceeding 12%). SPEs were almost exclusively related to a decrease in sensitivity at the primary seeding points but did not result in significant differences in other indices. Censoring sensitivity results ≤19 dB significantly improved the correlation between reliable and unreliable results.
Current criteria for judging an unreliable VF result (FP rate >15% and SPE) can lead to data being erroneously excluded, as many results do not show significant differences compared to those deemed “reliable.” Censoring of sensitivity results ≤19 dB improves intrasession correlations in VF results.
We provide guidelines for assessing the impact of FP, SPE, and low sensitivity results on VF interpretation.
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