Volume 8 Issue 6 | TVST | ARVO Journals

Influence of Charge, Hydrophobicity, and Size on Vitreous Pharmacokinetics of Large Molecules Open Access

Susan R. Crowell; Kathryn Wang; Amin Famili; Whitney Shatz; Kelly M. Loyet; Vincent Chang; Yanqiu Liu; Saileta Prabhu; Amrita V. Kamath; Robert F. Kelley

Tags: hydrophobicity, molecule, ranibizumab, vitreous body, pharmacokinetics

Translational Vision Science & Technology November 2019, Vol.8, 1. doi:https://doi.org/10.1167/tvst.8.6.1

Physicochemical Properties of Hyaluronic Acid–Based Lubricant Eye Drops Open Access

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Pasquale Aragona; Peter A. Simmons; Hongpeng Wang; Tao Wang

Tags: hyaluronic acid, mass or substance concentration per volume, ocular lubricants, viscosity, sodium

Translational Vision Science & Technology November 2019, Vol.8, 2. doi:https://doi.org/10.1167/tvst.8.6.2

Presymptomatic Retinal Sensitivity Changes in Intermediate Age-Related Macular Degeneration Associated With New Retinal Fluid Open Access

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Antony J. Wightman; Carla J. Abbott; Myra B. McGuinness; Emily Caruso; Robyn H. Guymer; Chi D. Luu

Tags: age-related macular degeneration, eye, spectral domain-optical coherence tomography, cohort studies

Translational Vision Science & Technology November 2019, Vol.8, 3. doi:https://doi.org/10.1167/tvst.8.6.3

Automatic Detection of Diabetic Retinopathy in Retinal Fundus Photographs Based on Deep Learning Algorithm Open Access

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Feng Li; Zheng Liu; Hua Chen; Minshan Jiang; Xuedian Zhang; Zhizheng Wu

Tags: datasets, deep learning, diabetic retinopathy, fundus photography, learning

Translational Vision Science & Technology November 2019, Vol.8, 4. doi:https://doi.org/10.1167/tvst.8.6.4

Impact of Bleaching on Photoreceptors in Different Intermediate AMD Phenotypes Open Access

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Enrico Borrelli; Eliana Costanzo; Mariacristina Parravano; Pasquale Viggiano; Monica Varano; Paola Giorno; Alessandro Marchese; Riccardo Sacconi; Leonardo Mastropasqua; Francesco Bandello; Giuseppe Querques

Tags: phenotype, photoreceptors, volume, eye, diagnostic imaging

Translational Vision Science & Technology November 2019, Vol.8, 5. doi:https://doi.org/10.1167/tvst.8.6.5

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases Open Access

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Mathieu Robin; Hong Liang; Ghislaine Rabut; Edouard Augstburger; Christophe Baudouin; Antoine Labbé

Tags: meibomian gland, pathophysiology, hypersensitivity, schirmer tear test procedure, signs and symptoms

Translational Vision Science & Technology November 2019, Vol.8, 6. doi:https://doi.org/10.1167/tvst.8.6.6

Fluorophotometric Determination of Riboflavin Concentrations in a Human Artificial Anterior Chamber Model Open Access

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Katja C. Iselin; Michael A. Thiel; Lucas M. Bachmann; Philipp B. Baenninger; Claude Kaufmann

Tags: anterior chamber of eye, cornea, riboflavin, iselin's disease

Translational Vision Science & Technology November 2019, Vol.8, 7. doi:https://doi.org/10.1167/tvst.8.6.7

Efficacy of Strip Meniscometry for Detecting Lacrimal Obstructive Diseases Among Patients With Epiphora Open Access

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Sho Ishikawa; Takuhei Shoji; Norihiro Yamada; Kei Shinoda

Tags: excessive tearing, trimethylamine, tissue microarray, surgical procedures, operative

Translational Vision Science & Technology November 2019, Vol.8, 8. doi:https://doi.org/10.1167/tvst.8.6.8

Gas-Graft Coverage After DMEK: A Clinically Validated Numeric Study Open Access

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Jan O. Pralits; Mark Alberti; Javier Cabrerizo

Tags: descemet's membrane endothelial keratoplasty, tissue transplants, eye

Translational Vision Science & Technology December 2019, Vol.8, 9. doi:https://doi.org/10.1167/tvst.8.6.9

Automatic Detection of Cone Photoreceptors With Fully Convolutional Networks Open Access

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Jared Hamwood; David Alonso-Caneiro; Danuta M. Sampson; Michael J. Collins; Fred K. Chen

Tags: retinal cone, datasets

Translational Vision Science & Technology November 2019, Vol.8, 10. doi:https://doi.org/10.1167/tvst.8.6.10

Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models Open Access

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Jan Tode; Elisabeth Richert; Stefan Koinzer; Alexa Klettner; Claus von der Burchard; Ralf Brinkmann; Ralph Lucius; Johann Roider

Tags: age-related macular degeneration, biological response modifiers, eye, mice, retina

Translational Vision Science & Technology November 2019, Vol.8, 11. doi:https://doi.org/10.1167/tvst.8.6.11

A Panel of Circulating MicroRNAs Detects Uveal Melanoma With High Precision Open Access

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Mitchell S. Stark; Elin S. Gray; Timothy Isaacs; Fred K. Chen; Michael Millward; Ashleigh McEvoy; Pauline Zaenker; Melanie Ziman; H. Peter Soyer; William J. Glasson; Sunil K. Warrier; Andrew L. Stark; Olivia J. Rolfe; Jane M. Palmer; Nicholas K. Hayward

Tags: intraocular melanoma, micrornas, precision

Translational Vision Science & Technology November 2019, Vol.8, 12. doi:https://doi.org/10.1167/tvst.8.6.12

Observational Clinical Studies of Human Lens Transparency Using the Vision Index Pen Open Access

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Azin Abazari; Harbans S. Dhadwal; John Wittpenn

Tags: lens, crystalline, transparency, vision, cataract, lens (device)

Translational Vision Science & Technology November 2019, Vol.8, 14. doi:https://doi.org/10.1167/tvst.8.6.14

An Objective Comparison of Light Intensity and Near-Visual Tasks Between Rural and Urban School Children in China by a Wearable Device Clouclip Open Access

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Longbo Wen; Qian Cheng; Weizhong Lan; Yingpin Cao; Xiaoning Li; Yiqiu Lu; Zhenghua Lin; Lun Pan; Haogang Zhu; Zhikuan Yang

Tags: china, light intensity, school (environment), school-age child, student

Translational Vision Science & Technology November 2019, Vol.8, 15. doi:https://doi.org/10.1167/tvst.8.6.15

Comparing Spatial Contrast Sensitivity Functions Measured With Digit and Grating Stimuli Open Access

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Haiyan Zheng; Menglu Shen; Xianghang He; Rong Cui; Luis Andres Lesmes; Zhong-Lin Lu; Fang Hou

Tags: cerebrospinal fluid analysis, colony-stimulating factors, contrast sensitivity, spatial frequency, precision

Translational Vision Science & Technology November 2019, Vol.8, 16. doi:https://doi.org/10.1167/tvst.8.6.16

Repeatability of Optical Coherence Tomography Angiography in Uveitic Eyes Open Access

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Sonny Caplash; Shilpa Kodati; Shuk Kei Cheng; Marib Akanda; Susan Vitale; Ian Thompson; Sapna Gangaputra; H. Nida Sen

Tags: angiogram, chief complaint, eye, fluid flow, optical coherence tomography

Translational Vision Science & Technology November 2019, Vol.8, 17. doi:https://doi.org/10.1167/tvst.8.6.17

Imaging Artifacts and Segmentation Errors With Wide-Field Swept-Source Optical Coherence Tomography Angiography in Diabetic Retinopathy Open Access

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Ying Cui; Ying Zhu; Jay C. Wang; Yifan Lu; Rebecca Zeng; Raviv Katz; David M. Wu; Demetrios G. Vavvas; Deeba Husain; Joan W. Miller; Leo A. Kim; John B. Miller

Tags: angiogram, artifacts, diabetic retinopathy, diagnostic imaging, optical coherence tomography

Translational Vision Science & Technology November 2019, Vol.8, 18. doi:https://doi.org/10.1167/tvst.8.6.18

Objective Measurement of Local Rod and Cone Function Using Gaze-Controlled Chromatic Pupil Campimetry in Healthy Subjects Open Access

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Carina Kelbsch; Katarina Stingl; Melanie Kempf; Torsten Strasser; Ronja Jung; Laura Kuehlewein; Helmut Wilhelm; Tobias Peters; Barbara Wilhelm; Krunoslav Stingl

Tags: constriction procedure, gaze, pupil, pupil reaction, retinal cone

Translational Vision Science & Technology November 2019, Vol.8, 19. doi:https://doi.org/10.1167/tvst.8.6.19

Dietary Spirulina Supplementation Protects Visual Function From Photostress by Suppressing Retinal Neurodegeneration in Mice Open Access

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Tomohiro Okamoto; Hirohiko Kawashima; Hideto Osada; Eriko Toda; Kohei Homma; Norihiro Nagai; Yasuyuki Imai; Kazuo Tsubota; Yoko Ozawa

Tags: diet, light exposure, mice, nerve degeneration, photoreceptors

Translational Vision Science & Technology November 2019, Vol.8, 20. doi:https://doi.org/10.1167/tvst.8.6.20

Deep Learning for Automatically Visual Evoked Potential Classification During Surgical Decompression of Sellar Region Tumors Open Access

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Nidan Qiao; Mengju Song; Zhao Ye; Wenqiang He; Zengyi Ma; Yongfei Wang; Yuyan Zhang; Xuefei Shou

Tags: decompression, surgical, deep learning, evoked potentials, visual, neoplasms

Translational Vision Science & Technology November 2019, Vol.8, 21. doi:https://doi.org/10.1167/tvst.8.6.21

Association Between Arterial Blood Gas Variation and Intraocular Pressure in Healthy Subjects Exposed to Acute Short-Term Hypobaric Hypoxia Open Access

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Yuan Xie; Yiquan Yang; Ying Han; Diya Yang; Yunxiao Sun; Xinmao Wang; Anh Hong Nguyen; Yihan Chen; Jiaxin Tian; Qing Zhang; Chen Xin; Kai Cao; Huaizhou Wang; Xiaofang Liu; Guozhong Wang; Ningli Wang

Tags: arterial blood gas, hypoxia, intraocular pressure, bicarbonates, sea level

Translational Vision Science & Technology November 2019, Vol.8, 22. doi:https://doi.org/10.1167/tvst.8.6.22

Deep Learning Algorithm for Automated Diagnosis of Retinopathy of Prematurity Plus Disease Open Access

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Zachary Tan; Samantha Simkin; Connie Lai; Shuan Dai

Tags: deep learning, retinopathy of prematurity, screening, negative predictive value, training

Translational Vision Science & Technology December 2019, Vol.8, 23. doi:https://doi.org/10.1167/tvst.8.6.23

Towards Automatically Controlled Dosing for Selective Laser Trabeculoplasty Open Access

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Katharina Bliedtner; Eric Seifert; Ralf Brinkmann

Tags: laser trabeculoplasty, lasers, modified barium swallow, optics, feedback

Translational Vision Science & Technology December 2019, Vol.8, 24. doi:https://doi.org/10.1167/tvst.8.6.24

Biomechanical and Morphologic Effects of Collagen Cross-Linking in Human Tarsus Open Access

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Shoaib Ugradar; Alan Le; Michael Lesgart; Robert A. Goldberg; Daniel Rootman; Joseph L. Demer

Tags: ankle, body tissue, corneal collagen cross-linking, cross-linking, tarsal bones

Translational Vision Science & Technology December 2019, Vol.8, 25. doi:https://doi.org/10.1167/tvst.8.6.25

OCTA-Based Identification of Different Vascular Patterns in Stargardt Disease Open Access

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Alessandro Arrigo; Francesco Romano; Emanuela Aragona; Carlo di Nunzio; Andrea Sperti; Francesco Bandello; Maurizio Battaglia Parodi

Tags: stargardt's disease

Translational Vision Science & Technology December 2019, Vol.8, 26. doi:https://doi.org/10.1167/tvst.8.6.26

Efficacy and Safety of Transglutaminase-Induced Corneal Stiffening in Rabbits Open Access

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Yuan Wu; Wenjing Song; Yun Tang; Ahmed Elsheikh; Yingfeng Shao; Xiaoming Yan

Tags: cornea, corneal collagen cross-linking, oryctolagus cuniculus, safety, transglutaminases

Translational Vision Science & Technology December 2019, Vol.8, 27. doi:https://doi.org/10.1167/tvst.8.6.27

Systematic Screening, Rational Development, and Initial Optimization of Efficacious RNA Silencing Agents for Human Rod Opsin Therapeutics Open Access

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Edwin H. Yau; Robert T. Taggart; Mohammed Zuber; Alexandria J. Trujillo; Zahra S. Fayazi; Mark C. Butler; Lowell G. Sheflin; Jennifer B. Breen; Dian Yu; Jack M. Sullivan

Tags: catalytic rna, opsin, rna, rna interference, rna, messenger

Translational Vision Science & Technology December 2019, Vol.8, 28. doi:https://doi.org/10.1167/tvst.8.6.28

Occurrence of Transmembrane Protein 119 in the Retina is Not Restricted to the Microglia: An Immunohistochemical Study Open Access

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Nan Su; Sigrid März; Tanja Plagemann; Jiahui Cao; Hans-Joachim Schnittler; Nicole Eter; Peter Heiduschka

Tags: antibodies, integral membrane proteins, mice, microglia, retina

Translational Vision Science & Technology December 2019, Vol.8, 29. doi:https://doi.org/10.1167/tvst.8.6.29

SRD005825 Acts as a Pharmacologic Chaperone of Opsin and Promotes Survival of Photoreceptors in an Animal Model of Autosomal Dominant Retinitis Pigmentosa Open Access

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Chulbul M. Ahmed; Brian T. Dwyer; Alla Romashko; Steve Van Adestine; Eun-Hee Park; Zhen Lou; Devin Welty; Serene Josiah; Anneli Savinainen; Bohong Zhang; Alfred S. Lewin

Tags: molecular chaperones, opsin, rhodopsin, animal model, retinitis pigmentosa

Translational Vision Science & Technology December 2019, Vol.8, 30. doi:https://doi.org/10.1167/tvst.8.6.30

Validation of Computerized Quantification of Ocular Redness Open Access

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Ekaterina Sirazitdinova; Marlies Gijs; Christian J. F. Bertens; Tos T. J. M. Berendschot; Rudy M. M. A. Nuijts; Thomas M. Deserno

Tags: automation, color, conjunctiva, eye, machine learning

Translational Vision Science & Technology December 2019, Vol.8, 31. doi:https://doi.org/10.1167/tvst.8.6.31

Impact of Pupil Diameter on Objective Refraction Determination and Predicted Visual Acuity Open Access

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Heather A. Anderson; Ayeswarya Ravikumar; Julia S. Benoit; Jason D. Marsack

Tags: diameter, pupil, refraction, visual acuity, eye

Translational Vision Science & Technology December 2019, Vol.8, 32. doi:https://doi.org/10.1167/tvst.8.6.32

Ability of Nonswelling Polyethylene Glycol-Based Vitreous Hydrogel to Maintain Transparency in the Presence of Vitreous Hemorrhage Open Access

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Sujin Hoshi; Fumiki Okamoto; Tomoya Murakami; Takamasa Sakai; Yuko Shinohara; Tomohiko Fujii; Masayoshi Nakatani; Tetsuro Oshika

Tags: glycols, hydrogel, polyethylene, vitreous body, vitreous hemorrhage

Translational Vision Science & Technology December 2019, Vol.8, 33. doi:https://doi.org/10.1167/tvst.8.6.33

Assessment of Corneal Fluorescein Staining in Different Dry Eye Subtypes Using Digital Image Analysis Open Access

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Marco Pellegrini; Federico Bernabei; Fabiana Moscardelli; Aldo Vagge; Riccardo Scotto; Cristina Bovone; Vincenzo Scorcia; Giuseppe Giannaccare

Tags: cornea, digital image analysis, dry eye syndromes, fluorescein stain method, reliability

Translational Vision Science & Technology December 2019, Vol.8, 34. doi:https://doi.org/10.1167/tvst.8.6.34

Nonlinear Optical Corneal Crosslinking, Mechanical Stiffening, and Corneal Flattening Using Amplified Femtosecond Pulses Open Access

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Samantha Bradford; Eric Mikula; Sun Woong Kim; Yilu Xie; Tibor Juhasz; Donald J. Brown; James V. Jester

Tags: cornea, corneal collagen cross-linking, optics, lasers

Translational Vision Science & Technology December 2019, Vol.8, 35. doi:https://doi.org/10.1167/tvst.8.6.35

Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity Open Access

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Francisco J. Valiente-Soriano; Arturo Ortín-Martínez; Johnny Di Pierdomenico; Diego García-Ayuso; Alejandro Gallego-Ortega; Juan A. Miralles de Imperial-Ollero; Manuel Jiménez-López; María Paz Villegas-Pérez; Larry A. Wheeler; Manuel Vidal-Sanz

Tags: brain-derived neurotrophic factor, brimonidine, ciliary neurotrophic factor, fibroblast growth factor 2, lip

Translational Vision Science & Technology December 2019, Vol.8, 36. doi:https://doi.org/10.1167/tvst.8.6.36

A Deep Learning Approach for Meibomian Gland Atrophy Evaluation in Meibography Images Open Access

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Jiayun Wang; Thao N. Yeh; Rudrasis Chakraborty; Stella X. Yu; Meng C. Lin

Tags: atrophy, deep learning, meibomian gland

Translational Vision Science & Technology December 2019, Vol.8, 37. doi:https://doi.org/10.1167/tvst.8.6.37

Noninvasive Imaging and Correlative Histology of Cone Photoreceptor Structure in the Pig Retina Open Access

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Alison L. Huckenpahler; Joseph Carroll; Alexander E. Salmon; Benjamin S. Sajdak; Rebecca R. Mastey; Kenneth P. Allen; Henry J. Kaplan; Maureen A. McCall

Tags: diagnostic imaging, histology, retina, retinal cone, suidae

Translational Vision Science & Technology December 2019, Vol.8, 38. doi:https://doi.org/10.1167/tvst.8.6.38

Confocal and Histological Features After Poly(Ethylene Glycol) Diacrylate Corneal Inlay Implantation Open Access

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Aritz Bidaguren; Javier Mendicute; Iratxe Madarieta; Nerea Garagorri

Tags: cornea, ethylene glycol, implantation procedure, implants, hydrogel

Translational Vision Science & Technology December 2019, Vol.8, 39. doi:https://doi.org/10.1167/tvst.8.6.39

Remote Tool-Based Adjudication for Grading Diabetic Retinopathy Open Access

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Mike Schaekermann; Naama Hammel; Michael Terry; Tayyeba K. Ali; Yun Liu; Brian Basham; Bilson Campana; William Chen; Xiang Ji; Jonathan Krause; Greg S. Corrado; Lily Peng; Dale R. Webster; Edith Law; Rory Sayres

Tags: diabetic retinopathy, participation in ward rounds, reliability, reference standards

Translational Vision Science & Technology December 2019, Vol.8, 40. doi:https://doi.org/10.1167/tvst.8.6.40

Standardizing the Assessment of Macular Pigment Using a Dual-Wavelength Autofluorescence Technique Open Access

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Marina Green-Gomez; Paul S. Bernstein; Christine A. Curcio; Rachel Moran; Warren Roche; John M. Nolan

Tags: autofluorescence, macular pigment, carotenoids

Translational Vision Science & Technology December 2019, Vol.8, 41. doi:https://doi.org/10.1167/tvst.8.6.41

Epigenetic Modifications in Peripheral Blood as Potential Noninvasive Biomarker of Diabetic Retinopathy Open Access

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Arul J. Duraisamy; Rakesh Radhakrishnan; Berhane Seyoum; Gary W. Abrams; Renu A. Kowluru

Tags: biological markers, diabetes mellitus, diabetic retinopathy, dna, dna methylation

Translational Vision Science & Technology December 2019, Vol.8, 43. doi:https://doi.org/10.1167/tvst.8.6.43

Residual Visual Responses in Patients With Retinitis Pigmentosa Revealed by Functional Magnetic Resonance Imaging Open Access

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Elisa Castaldi; Guido Marco Cicchini; Benedetto Falsini; Paola Binda; Maria Concetta Morrone

Tags: functional magnetic resonance imaging, retinitis pigmentosa, psychophysics, magnetic resonance imaging, photopsia

Translational Vision Science & Technology December 2019, Vol.8, 44. doi:https://doi.org/10.1167/tvst.8.6.44

Chromatic Full-Field Stimulus Threshold and Pupillography as Functional Markers for Late-Stage, Early-Onset Retinitis Pigmentosa Caused by CRB1 Mutations Open Access

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Krunoslav T. Stingl; Laura Kuehlewein; Nicole Weisschuh; Saskia Biskup; Frans P. M. Cremers; M. Imran Khan; Carina Kelbsch; Tobias Peters; Marius Ueffing; Barbara Wilhelm; Eberhart Zrenner; Katarina Stingl

Tags: eye, illness length, mutation, pupil reaction, retinitis pigmentosa

Translational Vision Science & Technology December 2019, Vol.8, 45. doi:https://doi.org/10.1167/tvst.8.6.45

Functional Relevance and Structural Correlates of Near Infrared and Short Wavelength Fundus Autofluorescence Imaging in ABCA4-Related Retinopathy Open Access

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Philipp L. Müller; Johannes Birtel; Philipp Herrmann; Frank G. Holz; Peter Charbel Issa; Martin Gliem

Tags: fundus autofluorescence imaging, retinal diseases, eye, diagnostic imaging

Translational Vision Science & Technology December 2019, Vol.8, 46. doi:https://doi.org/10.1167/tvst.8.6.46

Topical Trabodenoson Is Neuroprotective in a Rodent Model of Anterior Ischemic Optic Neuropathy (rNAION) Open Access

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Yan Guo; Zara Mehrabian; Mary A. Johnson; David S. Albers; Cadmus C. Rich; Rudolf A. Baumgartner; Steven L. Bernstein

Tags: anterior ischemic optic neuropathy, astrocytes, edema, eye, inflammation

Translational Vision Science & Technology December 2019, Vol.8, 47. doi:https://doi.org/10.1167/tvst.8.6.47

Microperimetry in Age-Related Macular Degeneration: An Evidence-Base for Pattern Deviation Probability Analysis in Microperimetry Open Access

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Nicola K. Cassels; John M. Wild; Tom H. Margrain; Chris Blyth; Victor Chong; Jennifer H. Acton

Tags: age-related macular degeneration, color, evidence-based practice

Translational Vision Science & Technology December 2019, Vol.8, 48. doi:https://doi.org/10.1167/tvst.8.6.48

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