Volume 9 Issue 7 | TVST | ARVO Journals

Computerized Adaptive Tests: Efficient and Precise Assessment of the Patient-Centered Impact of Diabetic Retinopathy Open Access

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Eva K. Fenwick; John Barnard; Alfred Gan; Bao Sheng Loe; Jyoti Khadka; Konrad Pesudovs; Ryan Man; Shu Yen Lee; Gavin Tan; Tien Y. Wong; Ecosse L. Lamoureux

Tags: cats, diabetic retinopathy, patient-centered care, precision, validity of results

Translational Vision Science & Technology June 2020, Vol.9, 3. doi:https://doi.org/10.1167/tvst.9.7.3

Depth-Dependent Corneal Biomechanical Properties in Normal and Keratoconic Subjects by Optical Coherence Elastography Open Access

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Vinicius S. De Stefano; Matthew R. Ford; Ibrahim Seven; William J. Dupps, Jr

Tags: cornea, elasticity imaging techniques, eye, keratoconus, optics

Translational Vision Science & Technology June 2020, Vol.9, 4. doi:https://doi.org/10.1167/tvst.9.7.4

Quantifiable In Vivo Imaging Biomarkers of Retinal Regeneration by Photoreceptor Cell Transplantation Open Access

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Ying V. Liu; Simrat K. Sodhi; Gilbert Xue; Derek Teng; Dzhalal Agakishiev; Minda M. McNally; Sarah Harris-Bookman; Caitlin McBride; Gregory J. Konar; Mandeep S. Singh

Tags: biological markers, diagnostic imaging, photoreceptors, transplantation, tissue transplants

Translational Vision Science & Technology June 2020, Vol.9, 5. doi:https://doi.org/10.1167/tvst.9.7.5

OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker Open Access

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Khashayar Nattagh; Hao Zhou; Nicholas Rinella; Qinqin Zhang; Yining Dai; Katharina G. Foote; Cathrine Keiner; Michael Deiner; Jacque L. Duncan; Travis C. Porco; Ruikang K. Wang; Daniel M. Schwartz

Tags: angiogram, atrophy, biological markers, chief complaint, fluid flow

Translational Vision Science & Technology June 2020, Vol.9, 6. doi:https://doi.org/10.1167/tvst.9.7.6

Microbial Cross-contamination in Multidose Eyedrops: The Impact of Instillation Angle and Bottle Geometry Open Access

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Alexandre Xavier da Costa; Maria Cecilia Zorat Yu; Denise de Freitas; Priscila Cardoso Cristovam; Lauren C. LaMonica; Vagner Rogerio dos Santos; José Alvaro Pereira Gomes

Tags: eyedrops

Translational Vision Science & Technology June 2020, Vol.9, 7. doi:https://doi.org/10.1167/tvst.9.7.7

A Mouse Model of Proliferative Vitreoretinopathy Induced by Intravitreal Injection of Gas and RPE Cells Open Access

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Alison Heffer; Victor Wang; Jayanth Sridhar; Steven E. Feldon; Richard T. Libby; Collynn F. Woeller; Ajay E. Kuriyan

Tags: injections, intravitreal injections, mice, retinal pigment cell, vitreoretinopathy, proliferative

Translational Vision Science & Technology June 2020, Vol.9, 9. doi:https://doi.org/10.1167/tvst.9.7.9

Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity Open Access

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Mohamed Ashraf; Konstantina Sampani; Omar Abu-Qamar; Jerry Cavallerano; Paolo S. Silva; Lloyd Paul Aiello; Jennifer K. Sun

Tags: angiogram, artifacts, blood capillaries, diabetic retinopathy, eye

Translational Vision Science & Technology June 2020, Vol.9, 10. doi:https://doi.org/10.1167/tvst.9.7.10

High-Speed, Ultrahigh-Resolution Spectral-Domain OCT with Extended Imaging Range Using Reference Arm Length Matching Open Access

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ByungKun Lee; Siyu Chen; Eric M. Moult; Yue Yu; A. Yasin Alibhai; Nihaal Mehta; Caroline R. Baumal; Nadia K. Waheed; James G. Fujimoto

Tags: diagnostic imaging, spectral domain-optical coherence tomography, motion, eye

Translational Vision Science & Technology June 2020, Vol.9, 12. doi:https://doi.org/10.1167/tvst.9.7.12

A Custom-Made Semiautomatic Analysis of Retinal Nonperfusion Areas After Dexamethasone for Diabetic Macular Edema Open Access

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Lisa Toto; Rossella D'Aloisio; Antonio Maria Chiarelli; Luca Di Antonio; Federica Evangelista; Giada D'Onofrio; Arcangelo Merla; Mariacristina Parravano; Guido Di Marzio; Rodolfo Mastropasqua

Tags: blood capillaries, dexamethasone, diabetic macular edema, ischemia, follow-up

Translational Vision Science & Technology June 2020, Vol.9, 13. doi:https://doi.org/10.1167/tvst.9.7.13

Data Acquisition, Processing, and Reduction for Home-Use Trial of a Wearable Video Camera-Based Mobility Aid Open Access

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Shrinivas Pundlik; Vilte Baliutaviciute; Mojtaba Moharrer; Alex R. Bowers; Gang Luo

Tags: mobility, mobility aid

Translational Vision Science & Technology June 2020, Vol.9, 14. doi:https://doi.org/10.1167/tvst.9.7.14

Correlation of Immunological Markers with Disease and Clinical Outcome Measures in Patients with Autoimmune Retinopathy Open Access

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Lynn K. Stanwyck; Weilin Chan; Arjun Sood; Gayatri Susarla; John Romano; Maria Pefkianaki; Kanishka Thiran Jayasundera; John R. Heckenlively; Steven K. Lundy; Lucia Sobrin

Tags: autoimmunity, retinal diseases, treatment outcome, b-lymphocytes

Translational Vision Science & Technology June 2020, Vol.9, 15. doi:https://doi.org/10.1167/tvst.9.7.15

Localized Photoreceptor Ablation Using Femtosecond Pulses Focused With Adaptive Optics Open Access

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Kamal R. Dhakal; Sarah Walters; Juliette E. McGregor; Christina Schwarz; Jennifer M. Strazzeri; Ebrahim Aboualizadeh; Brittany Bateman; Krystel R. Huxlin; Jennifer J. Hunter; David R. Williams; William H. Merigan

Tags: ablation, diagnostic imaging, lasers, optics, photoreceptors

Translational Vision Science & Technology June 2020, Vol.9, 16. doi:https://doi.org/10.1167/tvst.9.7.16

Cognitive Impairment and Lamina Cribrosa Thickness in Primary Open-Angle Glaucoma Open Access

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Seung Hyen Lee; Ji Won Han; Eun Ji Lee; Tae-Woo Kim; Hyunjoong Kim; Ki Woong Kim

Tags: cognitive impairment, cribriform plate, open-angle glaucoma, cognitive ability, glaucoma

Translational Vision Science & Technology June 2020, Vol.9, 17. doi:https://doi.org/10.1167/tvst.9.7.17

Microscope-integrated Intraoperative Optical Coherence Tomography for Anterior Segment Surgical Maneuvers Open Access

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Wangyi Fang; Qingchen Li; Jinyu Fan; Ning Tang; Jian Yu; Huan Xu; Yuan Zong; Chunhui Jiang; Guohua Shi; Xinghuai Sun

Tags: intraoperative care, microscopes, optical coherence tomography, surgical procedures, operative, cornea

Translational Vision Science & Technology June 2020, Vol.9, 18. doi:https://doi.org/10.1167/tvst.9.7.18

Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds Open Access

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Jason Charng; Paul G. Sanfilippo; Mary S. Attia; Monika Dolliver; Sukanya Arunachalam; Avenell L. Chew; Evan N. Wong; David A. Mackey; Fred K. Chen

Tags: eye, scotoma

Translational Vision Science & Technology June 2020, Vol.9, 19. doi:https://doi.org/10.1167/tvst.9.7.19

Assessment of AAV Dual Vector Safety in the Abca4^−/− Mouse Model of Stargardt Disease Open Access

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Michelle E. McClements; Alun R. Barnard; Peter Charbel Issa; Robert E. MacLaren

Tags: cohort studies, disease vectors, eye, injections, mice

Translational Vision Science & Technology June 2020, Vol.9, 20. doi:https://doi.org/10.1167/tvst.9.7.20

Quantification of RPE Changes in Choroideremia Using a Photoshop-Based Method Open Access

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Yi Zhai; Manlong Xu; Ioannis S. Dimopoulos; David G. Birch; Paul S. Bernstein; Jenny Holt; David Kirn; Peter Francis; Ian M. MacDonald

Tags: choroideremia, bland-altman plot

Translational Vision Science & Technology June 2020, Vol.9, 21. doi:https://doi.org/10.1167/tvst.9.7.21

Fractal Dimension Analysis of Widefield Choroidal Vasculature as Predictor of Stage of Macular Degeneration Open Access

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Benjamin K. Young; Kyle D. Kovacs; Ron A. Adelman

Tags: fractals, macular degeneration, vasculature

Translational Vision Science & Technology June 2020, Vol.9, 22. doi:https://doi.org/10.1167/tvst.9.7.22

A Comparison Between Refraction From an Adaptive Optics Visual Simulator and Clinical Refractions Open Access

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Juan Tabernero; Carles Otero; Shahina Pardhan

Tags: optics, refraction, refractive errors, simulators

Translational Vision Science & Technology June 2020, Vol.9, 23. doi:https://doi.org/10.1167/tvst.9.7.23

A Minimally Invasive Experimental Model of Acute Ocular Hypertension with Acute Angle Closure Characteristics Open Access

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Rachel S. Chong; Joanna M. F. Busoy; Bingyao Tan; Sia Wey Yeo; Ying Shi Lee; Amutha V. Barathi; Jonathan G. Crowston; Leopold Schmetterer

Tags: eye, intraocular pressure, ocular hypertension, surgical procedures, minimally invasive, sutures

Translational Vision Science & Technology June 2020, Vol.9, 24. doi:https://doi.org/10.1167/tvst.9.7.24

Presbyopia Treatment With Eye Drops: An Eight Year Retrospective Study Open Access

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Giovanna Benozzi; Cristian Perez; Juliana Leiro; Sonia Facal; Betina Orman

Tags: eyedrops, presbyopia, retrospective studies, follow-up

Translational Vision Science & Technology June 2020, Vol.9, 25. doi:https://doi.org/10.1167/tvst.9.7.25

Detecting Mechanical Anisotropy of the Cornea Using Brillouin Microscopy Open Access

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Joshua N. Webb; Hongyuan Zhang; Abhijit Sinha Roy; James Bradley Randleman; Giuliano Scarcelli

Tags: anisotropy, cornea, corneal collagen cross-linking

Translational Vision Science & Technology June 2020, Vol.9, 26. doi:https://doi.org/10.1167/tvst.9.7.26

Risks and Challenges in Interpreting Simultaneous Analyses of Multiple Cytokines Open Access

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Isabel B. Pfister; Souska Zandi; Christin Gerhardt; Jan Spindler; Natalie Reichen; Justus G. Garweg

Tags: cytokine, oprl1 gene

Translational Vision Science & Technology June 2020, Vol.9, 27. doi:https://doi.org/10.1167/tvst.9.7.27

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration Open Access

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Hongman Song; Yong Zeng; Sheik Pran Babu Sardar Pasha; Ronald A. Bush; Camasamudram Vijayasarathy; Haohua Qian; Lisa Wei; Henry E. Wiley; Zhijian Wu; Paul A. Sieving

Tags: eye, retina, spatial vectors, transfer technique, oryctolagus cuniculus

Translational Vision Science & Technology June 2020, Vol.9, 28. doi:https://doi.org/10.1167/tvst.9.7.28

Imaging of Therapeutic Effects of Anti-Vascular Endothelial Growth Factor Inhibitors by Optical Coherence Tomography Angiography in a Rat Model Open Access

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Johanna H. Meyer; Janine Marx; Claudine Strack; Frank G. Holz; Steffen Schmitz-Valckenberg

Tags: aflibercept, angiogram, animal model, choroidal neovascularization, diagnostic imaging

Translational Vision Science & Technology June 2020, Vol.9, 29. doi:https://doi.org/10.1167/tvst.9.7.29

Corneal Stromal Filler Injection as a Novel Approach to Correct Presbyopia—An Ex Vivo Pilot Study Open Access

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Stefan Kassumeh; Jannik K. Luther; Christian M. Wertheimer; Katharina Brandt; Merle S. Schenk; Siegfried G. Priglinger; Andreas Wartak; Gabriela Apiou-Sbirlea; R. Rox Anderson; Reginald Birngruber

Tags: cornea, injections, presbyopia, pilot projects

Translational Vision Science & Technology June 2020, Vol.9, 30. doi:https://doi.org/10.1167/tvst.9.7.30

Repeatability of Scotopic Sensitivity and Dark Adaptation Using a Medmont Dark-Adapted Chromatic Perimeter in Age-related Macular Degeneration Open Access

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Durin Uddin; Brett G. Jeffrey; Oliver Flynn; Wai Wong; Henry Wiley; Tiarnan Keenan; Emily Chew; Catherine Cukras

Tags: age-related macular degeneration, dark adaptation, rod photoreceptors, retinal cone

Translational Vision Science & Technology June 2020, Vol.9, 31. doi:https://doi.org/10.1167/tvst.9.7.31

An In Vitro Bovine Cellular Model for Human Schlemm's Canal Endothelial Cells and Their Response to TGFβ Treatment Open Access

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Jingwen Cai; Kristin Perkumas; W. Daniel Stamer; Yutao Liu

Tags: cattle, endothelial cells, genes, glaucoma, schlemm's canal

Translational Vision Science & Technology June 2020, Vol.9, 32. doi:https://doi.org/10.1167/tvst.9.7.32

Factors Influencing Retinal Pigment Epithelium-Atrophy Progression Rate in Stargardt Disease Open Access

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Maria Vittoria Cicinelli; Alessandro Rabiolo; Maria Brambati; Chiara Viganò; Francesco Bandello; Maurizio Battaglia Parodi

Tags: atrophy, stargardt's disease, pigment, epithelium, hypertrophy

Translational Vision Science & Technology June 2020, Vol.9, 33. doi:https://doi.org/10.1167/tvst.9.7.33

Repeatability and Reproducibility of Total Retinal Blood Flow Measurements Using Bi-Directional Doppler OCT Open Access

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Stephan Szegedi; Nikolaus Hommer; Martin Kallab; Stefan Puchner; Doreen Schmidl; René M. Werkmeister; Gerhard Garhöfer; Leopold Schmetterer

Tags: optical coherence tomography, vascular flow

Translational Vision Science & Technology June 2020, Vol.9, 34. doi:https://doi.org/10.1167/tvst.9.7.34

Development and Optimization of Freeze-Dried Eye Drops Derived From Plasma Rich in Growth Factors Technology Open Access

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Eduardo Anitua; María de la Fuente; Ignacio Alcalde; Cristina Sanchez; Jesús Merayo-Lloves; Francisco Muruzabal

Tags: eyedrops, freeze drying, growth factor, plasma

Translational Vision Science & Technology June 2020, Vol.9, 35. doi:https://doi.org/10.1167/tvst.9.7.35

Keratoconus Detection Based on a Single Scheimpflug Image Open Access

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Alejandra Consejo; Jędrzej Solarski; Karol Karnowski; Jos J Rozema; Maciej Wojtkowski; D. Robert Iskander

Tags: keratoconus, cornea, eye, pixel

Translational Vision Science & Technology June 2020, Vol.9, 36. doi:https://doi.org/10.1167/tvst.9.7.36

Intraobserver Repeatability and Interobserver Reproducibility of Foveal Cone Density Measurements in CNGA3- and CNGB3-Associated Achromatopsia Open Access

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Michalis Georgiou; Katie M. Litts; Navjit Singh; Thomas Kane; Emily J. Patterson; Nashila Hirji; Angelos Kalitzeos; Alfredo Dubra; Michel Michaelides; Joseph Carroll

Translational Vision Science & Technology November 2020, Vol.9, 37. doi:https://doi.org/10.1167/tvst.9.7.37

Preserved Corneal Lamellar Grafting Reduces Inflammation and Promotes Wound Healing in a Scleral Defect Rabbit Model Open Access

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Kyoung Woo Kim; Jin Suk Ryu; Jun Yeob Kim; Mee Kum Kim

Tags: cornea, inflammation, oryctolagus cuniculus, sclera, tissue transplants

Translational Vision Science & Technology June 2020, Vol.9, 38. doi:https://doi.org/10.1167/tvst.9.7.38

Characterization of Uveal Melanoma Cell Lines and Primary Tumor Samples in 3D Culture Open Access

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Karen Aughton; Haleh Shahidipour; Luna Djirackor; Sarah E. Coupland; Helen Kalirai

Tags: cell lines, neoplasms, spheroids, cellular, uveal melanoma

Translational Vision Science & Technology June 2020, Vol.9, 39. doi:https://doi.org/10.1167/tvst.9.7.39

Synchronization of a Removable Optical Element with an Eye Tracker: Test Case for Heterophoria Measurement Open Access

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Liat Gantz; Avi Caspi

Tags: eye, strabismus, optics

Translational Vision Science & Technology June 2020, Vol.9, 40. doi:https://doi.org/10.1167/tvst.9.7.40

Nanoscale Characteristics of Ocular Lipid Thin Films Using Kelvin Probe Force Microscopy Open Access

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Elizabeth Drolle; William Ngo; Zoya Leonenko; Lakshman Subbaraman; Lyndon Jones

Tags: lipids, microscopy, atomic force

Translational Vision Science & Technology June 2020, Vol.9, 41. doi:https://doi.org/10.1167/tvst.9.7.41

Cherenkov Luminescence Imaging for Assessment of Radioactive Plaque Position in Brachytherapy of Uveal Melanoma: An In Vivo Feasibility Study Open Access

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Jørgen Krohn; Yi-Chun Chen; Nils Ole Stabo-Eeg; Børge Hamre

Tags: brachytherapy, diagnostic imaging, feasibility studies, luminescence, neoplasms

Translational Vision Science & Technology June 2020, Vol.9, 42. doi:https://doi.org/10.1167/tvst.9.7.42

Reliability and Recommended Settings for Pediatric Circumpapillary Retinal Nerve Fiber Layer Imaging Using Hand-Held Optical Coherence Tomography Open Access

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Sonal D. Shah; Adnaan Haq; Shafak Toufeeq; Zhanhan Tu; Budor Edawaji; Joseph Abbott; Irene Gottlob; Frank A. Proudlock

Tags: reliability, retinal nerve fiber layer, diagnostic imaging, pediatrics, optical coherence tomography

Translational Vision Science & Technology June 2020, Vol.9, 43. doi:https://doi.org/10.1167/tvst.9.7.43

Limbal Metabolic Support Reduces Peripheral Corneal Edema with Contact-Lens Wear Open Access

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Young Hyun Kim; Meng C. Lin; Clayton J. Radke

Tags: contact lenses, cornea, corneal edema, edema, lens (device)

Translational Vision Science & Technology June 2020, Vol.9, 44. doi:https://doi.org/10.1167/tvst.9.7.44

Evaluation of Electrical Performance and Properties of Electroretinography Electrodes Open Access

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Tony T. C. Man; Yolanda W. Y. Yip; Frederick K. F. Cheung; Wing Sze Lee; Chi Pui Pang; Mårten Erik Brelén

Tags: electric impedance, electrolytes, electroretinography, gold, noise

Translational Vision Science & Technology June 2020, Vol.9, 45. doi:https://doi.org/10.1167/tvst.9.7.45

Impact of Scan Tilt on Quantitative Assessments Using Optical Coherence Tomography Angiography Open Access

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Yong Sok Ji; Ahmed Roshdy Alagorie; Iksoo Byon; SriniVas R. Sadda

Tags: angiogram, chief complaint, optical coherence tomography, eye

Translational Vision Science & Technology June 2020, Vol.9, 46. doi:https://doi.org/10.1167/tvst.9.7.46

Exome Sequencing in a Swiss Childhood Glaucoma Cohort Reveals CYP1B1 and FOXC1 Variants as Most Frequent Causes Open Access

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Elena Lang; Samuel Koller; Luzy Bähr; Marc Töteberg-Harms; David Atac; Françoise Roulez; Angela Bahr; Katharina Steindl; Silke Feil; Wolfgang Berger; Christina Gerth-Kahlert

Tags: cohort studies, glaucoma, congenital, whole exome sequencing, glaucoma

Translational Vision Science & Technology June 2020, Vol.9, 47. doi:https://doi.org/10.1167/tvst.9.7.47

Characterization of Meibomian Gland Atrophy and the Potential Risk Factors for Middle Aged to Elderly Patients With Cataracts Open Access

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Xiaolei Lin; Yue Wu; Yiqin Chen; Yuyu Zhao; Linfeng Xiang; Qi Dai; Yana Fu; Yinying Zhao; Yun-e Zhao

Tags: atrophy, cataract, meibomian gland, risk factors, older adult

Translational Vision Science & Technology June 2020, Vol.9, 48. doi:https://doi.org/10.1167/tvst.9.7.48

Comparison of Rates of Progression of Macular OCT Measures in Glaucoma Open Access

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Alessandro Rabiolo; Vahid Mohammadzadeh; Nima Fatehi; Esteban Morales; Anne L. Coleman; Simon K. Law; Joseph Caprioli; Kouros Nouri-Mahdavi

Tags: fecal transplantantation, glaucoma, outcome measures, eye

Translational Vision Science & Technology June 2020, Vol.9, 50. doi:https://doi.org/10.1167/tvst.9.7.50

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