Volume 9 Issue 9 | TVST | ARVO Journals

Hyperglycemia Augments Endothelin-1–Induced Constriction of Human Retinal Venules Open Access

Yen-Lin Chen; Robert H. Rosa, Jr.; Lih Kuo; Travis W. Hein

Tags: constriction procedure, endothelin-1, hyperglycemia, retinal venule, glucose

Translational Vision Science & Technology August 2020, Vol.9, 1. doi:https://doi.org/10.1167/tvst.9.9.1

Autofluorescence Lifetimes Measured with Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) Are Affected by Age, but Not by Pigmentation or Gender Open Access

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Lydia Sauer; Alexandra S. Vitale; Cole M. Milliken; Natalie K. Modersitzki; J. David Blount; Paul S. Bernstein

Tags: autofluorescence, diagnostic imaging, fluorescence, gender, ophthalmoscopy

Translational Vision Science & Technology August 2020, Vol.9, 2. doi:https://doi.org/10.1167/tvst.9.9.2

Tear Proteomic Predictive Biomarker Model for Ocular Graft Versus Host Disease Classification Open Access

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Olivia E. O'Leary; Andreas Schoetzau; Ludovic Amruthalingam; Nadine Geber-Hollbach; Kim Plattner; Paul Jenoe; Alexander Schmidt; Christoph Ullmer; Faye M. Drawnel; Sascha Fauser; Hendrik P. N. Scholl; Jakob Passweg; Joerg P. Halter; David Goldblum

Tags: biological markers, graft-versus-host disease, proteins

Translational Vision Science & Technology August 2020, Vol.9, 3. doi:https://doi.org/10.1167/tvst.9.9.3

Detection and Quantification of Retinal Neovascularization Using BrdU Incorporation Open Access

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Yan Shao; Jianglei Chen; Xiao-Rong Li; Jian-Xing Ma

Tags: bromodeoxyuridine, retinal neovascularization, mice, retina

Translational Vision Science & Technology August 2020, Vol.9, 4. doi:https://doi.org/10.1167/tvst.9.9.4

Retinal and Choroidal Vasculature in Patients with Marfan Syndrome Open Access

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Matteo Di Marino; Massimo Cesareo; Gianluca Aloe; Carlo Nucci; Clarissa Giannini; Alessio Martucci; Francesco Aiello; Calogera Pisano; Giovanni Ruvolo; Raffaele Mancino

Tags: marfan syndrome, retinal vasculature, vasculature

Translational Vision Science & Technology August 2020, Vol.9, 5. doi:https://doi.org/10.1167/tvst.9.9.5

Structured Laser Light Improves Tripping Hazard Recognition for People with Visual Impairments Open Access

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Michael Stahl; Eli Peli

Tags: lasers, visual impairment, laser-generated electromagnetic radiation, eye

Translational Vision Science & Technology August 2020, Vol.9, 6. doi:https://doi.org/10.1167/tvst.9.9.6

DS-7080a, a Selective Anti-ROBO4 Antibody, Shows Anti-Angiogenic Efficacy with Distinctly Different Profiles from Anti-VEGF Agents Open Access

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Yoshitaka Isumi; Shinko Hayashi; Tatsuya Inoue; Yasushi Yoshigae; Toshiyuki Sato; Jun Hasegawa; Toshinori Agatsuma

Tags: angiogenesis, antibodies, anti-vascular endothelial growth factor therapy, choroidal neovascularization, lasers

Translational Vision Science & Technology August 2020, Vol.9, 7. doi:https://doi.org/10.1167/tvst.9.9.7

Spectral-Domain Optical Coherence Tomography Is More Sensitive for Hydroxychloroquine-Related Structural Abnormalities Than Short-Wavelength and Near-Infrared Autofluorescence Open Access

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Ruben Jauregui; Rait Parmann; Yan Nuzbrokh; Stephen H. Tsang; Janet R. Sparrow

Tags: autofluorescence, diagnostic imaging, hydroxychloroquine, screening, spectral domain-optical coherence tomography

Translational Vision Science & Technology August 2020, Vol.9, 8. doi:https://doi.org/10.1167/tvst.9.9.8

Effect of Paracentesis on Retinal Function Associated With Changes in Intraocular Pressure Caused by Intravitreal Injections Open Access

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Kazuma Kitsu; Kei Shinoda; Yoshinobu Mizuno; Kazuma Yagura; Gaku Terauchi; Celso Soiti Matsumoto; Masato Ochi; Atsushi Mizota

Tags: intraocular pressure, intravitreal injections, paracentesis, surgical procedures, operative, anterior chamber paracentesis

Translational Vision Science & Technology August 2020, Vol.9, 10. doi:https://doi.org/10.1167/tvst.9.9.10

Effect of Defocus Incorporated Multiple Segments Spectacle Lens Wear on Visual Function in Myopic Chinese Children Open Access

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Carly Siu Yin Lam; Wing Chun Tang; Hua Qi; Hema Radhakrishnan; Keigo Hasegawa; Chi Ho To; W. Neil Charman

Tags: child, chinese (other dialects), lens (device), lens, crystalline, vision

Translational Vision Science & Technology August 2020, Vol.9, 11. doi:https://doi.org/10.1167/tvst.9.9.11

Detection of Functional Deterioration in Glaucoma by Trend Analysis Using Overlapping Clusters of Locations Open Access

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Stuart K. Gardiner; Steven L. Mansberger

Tags: glaucoma, trend, visual fields, eye

Translational Vision Science & Technology August 2020, Vol.9, 12. doi:https://doi.org/10.1167/tvst.9.9.12

Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms Open Access

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Brooke M. Justis; Casey E. Coburn; Ethan M. Tyler; Ryan S. Showalter; Brianna J. Dissler; Melissa Li; Nancy A. McNamara; Gordon W. Laurie; Robert L. McKown

Tags: antibodies, immunoassay, proteins, schirmer tear test procedure, protein measurement, total

Translational Vision Science & Technology August 2020, Vol.9, 13. doi:https://doi.org/10.1167/tvst.9.9.13

Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices Open Access

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Anmol A. Pardeshi; Abe E. Song; Naim Lazkani; Xiaobin Xie; Alex Huang; Benjamin Y. Xu

Tags: biometry, eye

Translational Vision Science & Technology August 2020, Vol.9, 14. doi:https://doi.org/10.1167/tvst.9.9.14

Auto-Processed Retinal Vessel Shadow View Images From Bedside Optical Coherence Tomography to Evaluate Plus Disease in Retinopathy of Prematurity Open Access

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Kai R. Seely; Kira L. Wang; Vincent Tai; S. Grace Prakalapakorn; Stephanie J. Chiu; Christian Viehland; Sara Grace; Joseph A. Izatt; Sharon F. Freedman; Cynthia A. Toth

Tags: eye, optical coherence tomography, retinal vessels, retinopathy of prematurity, vascular diseases

Translational Vision Science & Technology August 2020, Vol.9, 16. doi:https://doi.org/10.1167/tvst.9.9.16

Cost Effectiveness of Voretigene Neparvovec for RPE65-Mediated Inherited Retinal Degeneration in Germany Open Access

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Matthias Fritz Uhrmann; Birgit Lorenz; Christian Gissel

Tags: cost effectiveness, germany, retinal degeneration, rpe65 protein, voretigene neparvovec

Translational Vision Science & Technology August 2020, Vol.9, 17. doi:https://doi.org/10.1167/tvst.9.9.17

Results of First In Vivo Trial of an Acoustic Self-Tonometer Open Access

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Jan Osmers; Oskar Hoppe; Alicja Strzalkowska; Piotr Strzalkowski; Ágnes Patzkó; Stefan Arnold; Michael Sorg; Andreas Fischer

Tags: acoustics, tonometers, intraocular pressure, eye

Translational Vision Science & Technology August 2020, Vol.9, 18. doi:https://doi.org/10.1167/tvst.9.9.18

Factors Affecting Photopic Negative Response Recorded with RETeval System: Study of Young Healthy Subjects Open Access

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Kumiko Kato; Asako Sugawara; Ryunosuke Nagashima; Kengo Ikesugi; Masahiko Sugimoto; Mineo Kondo

Tags: electroretinography, eye, glaucoma, intraocular pressure, linear regression

Translational Vision Science & Technology August 2020, Vol.9, 19. doi:https://doi.org/10.1167/tvst.9.9.19

Topical Corneal Cross-Linking Solution Delivered Via Corneal Reservoir in Dutch-Belted Rabbits Open Access

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Mariya Zyablitskaya; Charles Jayyosi; Anna Takaoka; Kristin M. Myers; Leejee H. Suh; Takayuki Nagasaki; Stephen L. Trokel; David C. Paik

Tags: cornea, corneal collagen cross-linking, cross-linking, oryctolagus cuniculus, dutch

Translational Vision Science & Technology August 2020, Vol.9, 20. doi:https://doi.org/10.1167/tvst.9.9.20

Establishment and Characterization of a Unilateral UV-Induced Photoreceptor Degeneration Model in the C57Bl/6J Mouse Open Access

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Anna-Marina   van der Meer; Tanja Berger; Frank Müller; Ann Christina Foldenauer; Sandra Johnen; Peter Walter

Tags: eye, mice, mice, inbred c57bl, photoreceptors, retina

Translational Vision Science & Technology August 2020, Vol.9, 21. doi:https://doi.org/10.1167/tvst.9.9.21

Sleep in Myopic and Non-Myopic Children Open Access

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Lisa A. Ostrin; Scott A. Read; Stephen J. Vincent; Michael J. Collins

Tags: child, sleep, refractive errors

Translational Vision Science & Technology August 2020, Vol.9, 22. doi:https://doi.org/10.1167/tvst.9.9.22

Norms of Interocular Circumpapillary Retinal Nerve Fiber Layer Thickness Differences at 768 Retinal Locations Open Access

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Neda Baniasadi; Franziska G. Rauscher; Dian Li; Mengyu Wang; Eun Young Choi; Hui Wang; Thomas Peschel; Kerstin Wirkner; Toralf Kirsten; Joachim Thiery; Christoph Engel; Markus Loeffler; Tobias Elze

Tags: eye, retinal nerve fiber layer, glaucoma, heterogeneity of variance

Translational Vision Science & Technology August 2020, Vol.9, 23. doi:https://doi.org/10.1167/tvst.9.9.23

Evaluation of the Choroid in Women with Uncomplicated Pregnancy Open Access

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Li Su; Wongsiri Taweebanjongsin; Stephanie L. Gaw; Gilad Rabina; SriniVas R. Sadda; Irena Tsui

Tags: choroid, pregnancy, cortical blindness, chief complaint, eye

Translational Vision Science & Technology August 2020, Vol.9, 24. doi:https://doi.org/10.1167/tvst.9.9.24

Training-Induced Changes in Radial–Tangential Anisotropy of Visual Crowding Open Access

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Maka Malania; Maja Pawellek; Tina Plank; Mark W. Greenlee

Tags: anisotropy, blood oxygen level dependent, crowding, functional magnetic resonance imaging, perceptual learning

Translational Vision Science & Technology August 2020, Vol.9, 25. doi:https://doi.org/10.1167/tvst.9.9.25

Electrophysiological and Pupillometric Abnormalities in PROM1 Cone–Rod Dystrophy Open Access

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Jason C. Park; Frederick T. Collison; Gerald A. Fishman; J. Jason McAnany

Tags: electroretinography, passive leg raising, progressive cone-rod dystrophy, retinitis pigmentosa, luminance

Translational Vision Science & Technology August 2020, Vol.9, 26. doi:https://doi.org/10.1167/tvst.9.9.26

Levosulpiride Increases the Levels of Prolactin and Antiangiogenic Vasoinhibin in the Vitreous of Patients with Proliferative Diabetic Retinopathy Open Access

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Carlos D. Nuñez-Amaro; Aura Ileana Moreno-Vega; Elva Adan-Castro; Magdalena Zamora; Renata Garcia-Franco; Paulina Ramirez-Neria; Marlon Garcia-Roa; Yolanda Villalpando; Juan Pablo Robles; Gabriela Ramirez-Hernandez; Mariana Lopez; Jorge Sanchez; Ellery Lopez-Star; Thomas Bertsch; Gonzalo Martinez de la Escalera; Ma. Ludivina Robles-Osorio; Jakob Triebel; Carmen Clapp

Tags: angiogenesis inhibitors, diabetes mellitus, prolactin, vitreous body, proliferative diabetic retinopathy

Translational Vision Science & Technology August 2020, Vol.9, 27. doi:https://doi.org/10.1167/tvst.9.9.27

Validating Fluorescent Chrnb4.EGFP Mouse Models for the Study of Cone Photoreceptor Degeneration Open Access

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Alicia A. Brunet; Paula I. Fuller-Carter; Annie L. Miller; Valentina Voigt; Sophia Vasiliou; Rabab Rashwan; David M. Hunt; Livia S. Carvalho

Tags: mice, retinal cone, tissue degeneration

Translational Vision Science & Technology August 2020, Vol.9, 28. doi:https://doi.org/10.1167/tvst.9.9.28

Stereotest Comparison: Efficacy, Reliability, and Variability of a New Glasses-Free Stereotest Open Access

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Alice Grasso McCaslin; Kathleen Vancleef; Luke Hubert; Jenny C.A. Read; Nicholas Port

Tags: eyeglasses, minor planets, reliability, preschools, tablet dosage form

Translational Vision Science & Technology August 2020, Vol.9, 29. doi:https://doi.org/10.1167/tvst.9.9.29

A New Contrast Sensitivity Test for Pediatric Patients: Feasibility and Inter-Examiner Reliability in Ocular Disorders and Cerebral Visual Impairment Open Access

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D. Luisa Mayer; Christopher Patrick Taylor; Barry S. Kran

Tags: brain, contrast sensitivity test, eye diseases, pediatrics, reliability

Translational Vision Science & Technology August 2020, Vol.9, 30. doi:https://doi.org/10.1167/tvst.9.9.30

A Novel Quantitative Index of Meibomian Gland Dysfunction, the Meibomian Gland Tortuosity Open Access

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Xiaolei Lin; Yana Fu; Lu Li; Chaoqiao Chen; Xuewen Chen; Yingyu Mao; Hengli Lian; Weihua Yang; Qi Dai

Tags: meibomian gland, meibomian gland dysfunction

Translational Vision Science & Technology August 2020, Vol.9, 34. doi:https://doi.org/10.1167/tvst.9.9.34

Peripapillary Retinal Nerve Fiber Layer Profile in Relation to Refractive Error and Axial Length: Results From the Gutenberg Health Study Open Access

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Felix Mathias Wagner; Esther Maria Hoffmann; Stefan Nickels; Achim Fiess; Thomas Münzel; Philipp S. Wild; Manfred E. Beutel; Irene Schmidtmann; Karl J. Lackner; Norbert Pfeiffer; Alexander Karl-Georg Schuster

Tags: eye, health, refractive errors, retinal nerve fiber layer, optic disk

Translational Vision Science & Technology August 2020, Vol.9, 35. doi:https://doi.org/10.1167/tvst.9.9.35

Written in Blood: Applying Shape Grammars to Retinal Vasculatures Open Access

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Ryan Y. Yeh; Ken K. Nischal; Philip LeDuc; Jonathan Cagan

Tags: grammar, retinal vasculature, shape, noise, surveys

Translational Vision Science & Technology August 2020, Vol.9, 36. doi:https://doi.org/10.1167/tvst.9.9.36

Functional Analysis of Rare Genetic Variants in Complement Factor I (CFI) using a Serum-Based Assay in Advanced Age-related Macular Degeneration Open Access

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Anuja Java; Peter Baciu; Rafael Widjajahakim; Yun Ju Sung; Jae Yang; David Kavanagh; John Atkinson; Johanna Seddon

Tags: age-related macular degeneration, complement factor i, cultural formulation interview, fibrinogen, genetics

Translational Vision Science & Technology August 2020, Vol.9, 37. doi:https://doi.org/10.1167/tvst.9.9.37

Merging Information From Infrared and Autofluorescence Fundus Images for Monitoring of Chorioretinal Atrophic Lesions Open Access

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Giovanni Ometto; Giovanni Montesano; Saman Sadeghi Afgeh; Georgios Lazaridis; Xiaoxuan Liu; Pearse A. Keane; David P. Crabb; Alastair K. Denniston

Tags: atrophic condition of skin, autofluorescence, datasets, pixel

Translational Vision Science & Technology August 2020, Vol.9, 38. doi:https://doi.org/10.1167/tvst.9.9.38

Integrating Differential Gene Expression Analysis with Perturbagen-Response Signatures May Identify Novel Therapies for Thyroid-Associated Orbitopathy Open Access

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John Y. Lee; Ryan A. Gallo; Paul J. Ledon; Wensi Tao; David T. Tse; Daniel Pelaez; Sara T. Wester

Tags: gene expression, molecule, thyroid, adipocytes, genes

Translational Vision Science & Technology August 2020, Vol.9, 39. doi:https://doi.org/10.1167/tvst.9.9.39

Enhancing Risk Assessment in Patients with Diabetic Retinopathy by Combining Measures of Retinal Function and Structure Open Access

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Mitchell G. Brigell; Bryce Chiang; April Yauguang Maa; C. Quentin Davis

Tags: diabetic retinopathy, risk assessment, electroretinography, diabetes mellitus

Translational Vision Science & Technology August 2020, Vol.9, 40. doi:https://doi.org/10.1167/tvst.9.9.40

An Artificial Intelligence Approach to Assess Spatial Patterns of Retinal Nerve Fiber Layer Thickness Maps in Glaucoma Open Access

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Mengyu Wang; Lucy Q. Shen; Louis R. Pasquale; Hui Wang; Dian Li; Eun Young Choi; Siamak Yousefi; Peter J. Bex; Tobias Elze

Tags: artificial intelligence, glaucoma, maps, retinal nerve fiber layer, eye

Translational Vision Science & Technology August 2020, Vol.9, 41. doi:https://doi.org/10.1167/tvst.9.9.41

Quantitative Fundus Autofluorescence in Systemic Chloroquine/Hydroxychloroquine Therapy Open Access

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Clara Reichel; Andreas Berlin; Victoria Radun; Ioana-Sandra Tarau; Jost Hillenkamp; Nikolai Kleefeldt; Kenneth R. Sloan; Thomas Ach

Tags: chloroquine, fundus autofluorescence imaging, hydroxychloroquine, macular disorders, spectral domain-optical coherence tomography

Translational Vision Science & Technology August 2020, Vol.9, 42. doi:https://doi.org/10.1167/tvst.9.9.42

The Utility of Corneal Nerve Fractal Dimension Analysis in Peripheral Neuropathies of Different Etiology Open Access

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Ioannis N. Petropoulos; Abdulrahman Al-Mohammedi; Xin Chen; Maryam Ferdousi; Georgios Ponirakis; Harriet Kemp; Reena Chopra; Scott Hau; Marc Schargus; Jan Vollert; Dietrich Sturm; Tina Bharani; Christopher Kleinschnitz; Mark Stettner; Tunde Peto; Christoph Maier; Andrew S. C. Rice; Rayaz A. Malik

Tags: cornea, fractals, neurons, peripheral neuropathy, polyneuropathy, demyelinating, inflammatory, chronic

Translational Vision Science & Technology August 2020, Vol.9, 43. doi:https://doi.org/10.1167/tvst.9.9.43

Aqueous Angiography in Normal Canine Eyes Open Access

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Jessica B. Burn; Alex S. Huang; Arthur J. Weber; Andras M. Komáromy; Chris G. Pirie

Tags: angiogram, eye, dog, domestic, injections, dyes

Translational Vision Science & Technology August 2020, Vol.9, 44. doi:https://doi.org/10.1167/tvst.9.9.44

Changes in Collagen Structure and Permeability of Rat and Human Sclera After Crosslinking Open Access

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Peng Guo; Yuan Miao; Yang Jing; Sruti Akella; Fang Wang; Choul Yong Park; Cheng Zhang; Roy S. Chuck

Tags: collagen, permeability, sclera, body tissue

Translational Vision Science & Technology August 2020, Vol.9, 45. doi:https://doi.org/10.1167/tvst.9.9.45

Endogenous or Exogenous Retinal Pigment Epithelial Cells: A Comparison of Two Experimental Animal Models of Proliferative Vitreoretinopathy Open Access

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Chee Wai Wong; Joanna Marie Fianza Busoy; Ning Cheung; Veluchamy Amutha Barathi; Gert Storm; Tina T. Wong

Tags: animals, laboratory, eye, retinal pigment cell, vitreoretinopathy, proliferative, vitreous body

Translational Vision Science & Technology August 2020, Vol.9, 46. doi:https://doi.org/10.1167/tvst.9.9.46

Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs’ Endothelial Corneal Dystrophy Open Access

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Ziye Rong; Xin Gong; John D. Hulleman; David R. Corey; V. Vinod Mootha

Tags: endothelium, hereditary corneal dystrophy, rna, dna, endothelial cells

Translational Vision Science & Technology August 2020, Vol.9, 47. doi:https://doi.org/10.1167/tvst.9.9.47

Quantitative Optical Coherence Tomography Angiography Parameters in Type 1 Macular Neovascularization Secondary to Age-Related Macular Degeneration Open Access

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Alessandro Arrigo; Emanuela Aragona; Carlo Di Nunzio; Francesco Bandello; Maurizio Battaglia Parodi

Tags: age-related macular degeneration, angiogram, follow-up, neovascularization, pathologic, optical coherence tomography

Translational Vision Science & Technology August 2020, Vol.9, 48. doi:https://doi.org/10.1167/tvst.9.9.48

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