Volume 10 Issue 4 | TVST

Developmental Effects on Pattern Visual Evoked Potentials Characterized by Principal Component Analysis Open Access

Carlyn Patterson Gentile; Nabin R. Joshi; Kenneth J. Ciuffreda; Kristy B. Arbogast; Christina Master; Geoffrey K. Aguirre

Tags: evoked potentials, visual, principal component analysis, datasets, cohort studies, reliability

Translational Vision Science & Technology April 2021, Vol.10, 1. doi:https://doi.org/10.1167/tvst.10.4.1

Intraocular Pressure Reduction Effect of 0.005% Latanoprost Eye Drops in a Hyaluronic Acid-Chitosan Nanoparticle Drug Delivery System in Albino Rabbits Open Access

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Ana Marie L. Rubenicia; Leo D. P. Cubillan; Victor Arni D. P. Sicam; Allan Patrick G. Macabeo; Oliver B. Villaflores; Agnes L. Castillo

Tags: albinism, eyedrops, intraocular pressure, latanoprost, oryctolagus cuniculus

Translational Vision Science & Technology April 2021, Vol.10, 2. doi:https://doi.org/10.1167/tvst.10.4.2

Association Between the Types of Posterior Staphyloma and Their Risk Factors in Pathological Myopia Open Access

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Guangqi An; Fangfang Dai; Rui Wang; Zhenhui Liu; Ju Guo; Meng Pan; Xuemin Jin; Bo Lei

Tags: 3d mri, eye, myopia, risk factors, staphyloma

Translational Vision Science & Technology April 2021, Vol.10, 5. doi:https://doi.org/10.1167/tvst.10.4.5

Omidenepag, a Selective, Prostanoid EP2 Agonist, Does Not Suppress Adipogenesis in 3D Organoids of Human Orbital Fibroblasts Open Access

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Fumihito Hikage; Yosuke Ida; Yuika Ouchi; Megumi Watanabe; Hiroshi Ohguro

Tags: agonists, fibroblasts, organoids, prostaglandins

Translational Vision Science & Technology April 2021, Vol.10, 6. doi:https://doi.org/10.1167/tvst.10.4.6

Predictive Association of Pre-Operative Defect Areas in the Outer Retinal Layers With Visual Acuity in Macular Hole Surgery Open Access

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Carmen Baumann; Danilo Iannetta; Ziyaad Sultan; Ian A. Pearce; Chris P. Lohmann; Yalin Zheng; Stephen B. Kaye

Tags: embryonic lethal mutation, repair of hole of macula lutea, visual acuity, postoperative care

Translational Vision Science & Technology April 2021, Vol.10, 7. doi:https://doi.org/10.1167/tvst.10.4.7

Initiation of L-DOPA Treatment After Detection of Diabetes-Induced Retinal Dysfunction Reverses Retinopathy and Provides Neuroprotection in Rats Open Access

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Kyle Chesler; Cara Motz; Harrison Vo; Amber Douglass; Rachael S. Allen; Andrew J. Feola; Machelle T. Pardue

Tags: diabetes mellitus, levodopa, rats, diabetes mellitus, type 2, dopamine

Translational Vision Science & Technology April 2021, Vol.10, 8. doi:https://doi.org/10.1167/tvst.10.4.8

Durability of VEGF Suppression With Intravitreal Aflibercept and Brolucizumab: Using Pharmacokinetic Modeling to Understand Clinical Outcomes Open Access

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Thomas Eissing; Michael W. Stewart; Cynthia X. Qian; Kay D. Rittenhouse

Tags: aflibercept, anti-vascular endothelial growth factor therapy, brolucizumab, vascular endothelial growth factor a, treatment outcome

Translational Vision Science & Technology April 2021, Vol.10, 9. doi:https://doi.org/10.1167/tvst.10.4.9

Effect of CPAP Therapy on 24-Hour Intraocular Pressure-Related Pattern From Contact Lens Sensors in Obstructive Sleep Apnea Syndrome Open Access

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María Jesús Muniesa; Iván Benítez; Juan Ezpeleta; Manuel Sánchez de la Torre; Marta Pazos; Elena Millà; Ferrán Barbé

Tags: contact lenses, continuous positive airway pressure, intraocular pressure, obstructive sleep apnea, sensor

Translational Vision Science & Technology April 2021, Vol.10, 10. doi:https://doi.org/10.1167/tvst.10.4.10

Validation of a Novel Automated Algorithm to Measure Drusen Volume and Area Using Swept Source Optical Coherence Tomography Angiography Open Access

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Xiaoshuang Jiang; Mengxi Shen; Liang Wang; Luis de Sisternes; Mary K. Durbin; William Feuer; Philip J. Rosenfeld; Giovanni Gregori

Tags: angiogram, drusen, optical coherence tomography, volume, spectral domain-optical coherence tomography

Translational Vision Science & Technology April 2021, Vol.10, 11. doi:https://doi.org/10.1167/tvst.10.4.11

Evaluating Contrast Sensitivity in Asian Indian Pre-Term Infants With and Without Retinopathy of Prematurity Open Access

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Rwituja Thomas; Anand Vinekar; Shwetha Mangalesh; Thirumalesh Basavaraj Mochi; Puja Sarbajna; Bhujang Shetty

Tags: asian indians, contrast sensitivity, infant, infant, premature, retinopathy of prematurity

Translational Vision Science & Technology April 2021, Vol.10, 12. doi:https://doi.org/10.1167/tvst.10.4.12

Can the Macula be Attached if View Is Obscured by a Bullous Retinal Detachment? A Mathematical Consideration Open Access

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William E. Smiddy; Lev Kapitanski; Harry W. Flynn

Tags: macula lutea, mathematics, retina, retinal detachment, fovea centralis

Translational Vision Science & Technology April 2021, Vol.10, 13. doi:https://doi.org/10.1167/tvst.10.4.13

Longitudinal Development of Refractive Error in Children Treated With Intravitreal Bevacizumab or Laser for Retinopathy of Prematurity Open Access

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Michael Simmons; Jingyun Wang; Joel N. Leffler; Shanshan Li; Sarah E. Morale; Angie de la Cruz; Eileen E. Birch

Tags: anisometropia, bevacizumab, child, lasers, refractive errors

Translational Vision Science & Technology April 2021, Vol.10, 14. doi:https://doi.org/10.1167/tvst.10.4.14

Estimating Ganglion Cell Complex Rates of Change With Bayesian Hierarchical Models Open Access

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Vahid Mohammadzadeh; Erica Su; Sepideh Heydar Zadeh; Simon K. Law; Anne L. Coleman; Joseph Caprioli; Robert E. Weiss; Kouros Nouri-Mahdavi

Tags: eye, ganglia, glaucoma, heterogeneity of variance, trend

Translational Vision Science & Technology April 2021, Vol.10, 15. doi:https://doi.org/10.1167/tvst.10.4.15

Strategies to Improve Convolutional Neural Network Generalizability and Reference Standards for Glaucoma Detection From OCT Scans Open Access

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Kaveri A. Thakoor; Xinhui Li; Emmanouil Tsamis; Zane Z. Zemborain; Carlos Gustavo De Moraes; Paul Sajda; Donald C. Hood

Tags: convolutional neural networks, datasets, glaucoma, reference standards, retinal nerve fiber layer

Translational Vision Science & Technology April 2021, Vol.10, 16. doi:https://doi.org/10.1167/tvst.10.4.16

Automated Quantification of Pathological Fluids in Neovascular Age-Related Macular Degeneration, and Its Repeatability Using Deep Learning Open Access

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Irmela Mantel; Agata Mosinska; Ciara Bergin; Maria Sole Polito; Jacopo Guidotti; Stefanos Apostolopoulos; Carlos Ciller; Sandro De Zanet

Tags: body fluid, datasets, deep learning, exudative age-related macular degeneration, volume

Translational Vision Science & Technology April 2021, Vol.10, 17. doi:https://doi.org/10.1167/tvst.10.4.17

The ROCK Inhibitor Ripasudil Shows an Endothelial Protective Effect in Patients With Low Corneal Endothelial Cell Density After Cataract Surgery Open Access

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Hisataka Fujimoto; Yoshinao Setoguchi; Junichi Kiryu

Tags: cataract surgery, cornea, endothelial cells, endothelium, surgical procedures, operative

Translational Vision Science & Technology April 2021, Vol.10, 18. doi:https://doi.org/10.1167/tvst.10.4.18

Corneal Immune Cells Are Increased in Patients With Multiple Sclerosis Open Access

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Adnan Khan; Yi Li; Georgios Ponirakis; Naveed Akhtar; Hoda Gad; Pooja George; Faiza M. Ibrahim; Ioannis N. Petropoulos; Beatriz G. Canibano; Dirk Deleu; Ashfaq Shuaib; Saadat Kamran; Rayaz A. Malik

Tags: cornea, multiple sclerosis, neurons, ciliary motility disorders, multiple sclerosis, relapsing-remitting

Translational Vision Science & Technology April 2021, Vol.10, 19. doi:https://doi.org/10.1167/tvst.10.4.19

Spleen Tyrosine Kinase Mediates Microglial Activation in Mice With Diabetic Retinopathy Open Access

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Xiaozhe Liu; Bing Xu; Shihao Gao

Tags: diabetes mellitus, mice, microglia, retina, streptozocin

Translational Vision Science & Technology April 2021, Vol.10, 20. doi:https://doi.org/10.1167/tvst.10.4.20

Improvement of Evaporative Dry Eye With Meibomian Gland Dysfunction in Model Mice by Treatment With Ophthalmic Solution Containing Mineral Oil Open Access

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Keisuke Watanabe; Masataka Yoshida; Takashi Okumura; Takayuki Sassa; Akio Kihara; Akira Uchiyama

Tags: dry eye syndromes, meibomian gland dysfunction, mice, mineral oil, ophthalmic solutions

Translational Vision Science & Technology April 2021, Vol.10, 21. doi:https://doi.org/10.1167/tvst.10.4.21

A Deep Learning Model for Screening Multiple Abnormal Findings in Ophthalmic Ultrasonography (With Video) Open Access

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Di Chen; Yi Yu; Yiwen Zhou; Bin Peng; Yujing Wang; Shan Hu; Miao Tian; Shanshan Wan; Yuelan Gao; Ying Wang; Yulin Yan; Lianlian Wu; LiWen Yao; Biqing Zheng; Yang Wang; Yuqing Huang; Xi Chen; Honggang Yu; Yanning Yang

Tags: datasets, deep learning, ophthalmic ultrasonography, ophthalmologists, screening

Translational Vision Science & Technology April 2021, Vol.10, 22. doi:https://doi.org/10.1167/tvst.10.4.22

Automatic Segmentation in Multiple OCT Layers For Stargardt Disease Characterization Via Deep Learning Open Access

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Zubin Mishra; Ziyuan Wang; SriniVas R. Sadda; Zhihong Hu

Tags: deep learning, stargardt's disease, eye

Translational Vision Science & Technology April 2021, Vol.10, 24. doi:https://doi.org/10.1167/tvst.10.4.24

Computational Model-Based Estimation of Mouse Eyeball Structure From Two-Dimensional Flatmount Microscopy Images Open Access

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Hongxiao Li; Hanyi Yu; Yong-Kyu Kim; Fusheng Wang; George Teodoro; Yi Jiang; John M. Nickerson; Jun Kong

Tags: body tissue, eye, mice, cornea

Translational Vision Science & Technology April 2021, Vol.10, 25. doi:https://doi.org/10.1167/tvst.10.4.25

High-Pass Visual Acuity Loss and Macular Structure-Function Relationship in Patients With Primary Open-Angle Glaucoma Open Access

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Yun Wen; Zidong Chen; Chengguo Zuo; Yangfan Yang; Jiangang Xu; Yang Kong; Hui Cheng; Minbin Yu

Tags: glaucoma, open-angle glaucoma, reduced visual acuity, eye, visual acuity

Translational Vision Science & Technology April 2021, Vol.10, 26. doi:https://doi.org/10.1167/tvst.10.4.26

Determining the Theoretical Effective Lens Position of Thick Intraocular Lenses for Machine Learning–Based IOL Power Calculation and Simulation Open Access

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Damien Gatinel; Guillaume Debellemanière; Alain Saad; Mathieu Dubois; Radhika Rampat

Tags: cornea, eye, intraocular lens implant device, lens (device), lens, crystalline

Translational Vision Science & Technology April 2021, Vol.10, 27. doi:https://doi.org/10.1167/tvst.10.4.27

Smart Eye Camera: A Validation Study for Evaluating the Tear Film Breakup Time in Human Subjects Open Access

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Eisuke Shimizu; Hiroyuki Yazu; Naohiko Aketa; Ryota Yokoiwa; Shinri Sato; Taiichiro Katayama; Akiko Hanyuda; Yasunori Sato; Yoko Ogawa; Kazuo Tsubota

Tags: dry eye syndromes, eye, microscopes, slit lamps, tear film finding

Translational Vision Science & Technology April 2021, Vol.10, 28. doi:https://doi.org/10.1167/tvst.10.4.28

Neuroretinal Biomarkers for Schizophrenia Spectrum Disorders Open Access

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Samuel Asanad; Hugh O'Neill; Hampton Addis; Shuo Chen; Jingtao Wang; Eric Goldwaser; Peter Kochunov; L. Elliot Hong; Osamah J. Saeedi

Tags: biological markers, retina, retinal nerve fiber layer, schizophrenia, intraocular pressure

Translational Vision Science & Technology April 2021, Vol.10, 29. doi:https://doi.org/10.1167/tvst.10.4.29

Abnormal Dynamic Pupillometry Relates to Neurologic Disability and Retinal Axonal Loss in Patients With Multiple Sclerosis Open Access

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Gulfidan Bitirgen; Zehra Akpinar; Huseyin B. Turk; Rayaz A. Malik

Tags: disability, multiple sclerosis, pupil reaction, pupillometry, medical history

Translational Vision Science & Technology April 2021, Vol.10, 30. doi:https://doi.org/10.1167/tvst.10.4.30

Intravital Imaging of Circulating Red Blood Cells in the Retinal Vasculature of Growing Mice Open Access

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Jehwi Jeon; Yoonha Hwang; Jingu Lee; Eunji Kong; Jieun Moon; Sujung Hong; Pilhan Kim

Tags: diagnostic imaging, erythrocytes, fluid flow, mice, retinal vasculature

Translational Vision Science & Technology April 2021, Vol.10, 31. doi:https://doi.org/10.1167/tvst.10.4.31

A Novel Rabbit Dry Eye Model Induced by a Controlled Drying System Open Access

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Xiao-Min Chen; Jian-Biao Kuang; Hui-Yin Yu; Zhen-Ning Wu; Shu-Yi Wang; Shi-You Zhou

Tags: conjunctiva, cornea, desiccation, dry eye syndromes, eye

Translational Vision Science & Technology April 2021, Vol.10, 32. doi:https://doi.org/10.1167/tvst.10.4.32

The Influence of Cataract on Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) Open Access

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Joel-Benjamin Lincke; Chantal Dysli; Damian Jaggi; Rahel Fink; Sebastian Wolf; Martin S. Zinkernagel

Tags: cataract, diagnostic imaging, fluorescence, lens, crystalline, ophthalmoscopy

Translational Vision Science & Technology April 2021, Vol.10, 33. doi:https://doi.org/10.1167/tvst.10.4.33

Assessment of Generative Adversarial Networks for Synthetic Anterior Segment Optical Coherence Tomography Images in Closed-Angle Detection Open Access

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Ce Zheng; Fang Bian; Luo Li; Xiaolin Xie; Hui Liu; Jianheng Liang; Xu Chen; Zilei Wang; Tong Qiao; Jianlong Yang; Mingzhi Zhang

Tags: datasets, optical coherence tomography, training, glaucoma, specialism

Translational Vision Science & Technology April 2021, Vol.10, 34. doi:https://doi.org/10.1167/tvst.10.4.34

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