Volume 10 Issue 6 | TVST

Automatic Recording of the Target Location During Smooth Pursuit Eye Movement Testing Using Video-Oculography and Deep Learning-Based Object Detection Open Access

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Masakazu Hirota; Takao Hayashi; Emiko Watanabe; Yuji Inoue; Atsushi Mizota

Tags: eye, eye movement, learning, pursuit, smooth, strabismus

Translational Vision Science & Technology May 2021, Vol.10, 1. doi:https://doi.org/10.1167/tvst.10.6.1

Model Structure Uncertainty in the Characterization and Growth of Geographic Atrophy Open Access

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Janan Arslan; Kurt K. Benke; Gihan Samarasinghe; Arcot Sowmya; Robyn H. Guymer; Paul N. Baird

Tags: atrophy, regression analysis, eye, surgical instruments

Translational Vision Science & Technology May 2021, Vol.10, 2. doi:https://doi.org/10.1167/tvst.10.6.2

Comprehensive Proteomic Profiling of Aqueous Humor Proteins in Proliferative Diabetic Retinopathy Open Access

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Hu Xiao; Wen Xin; Li Mei Sun; Song Shan Li; Ting Zhang; Xiao Yan Ding

Tags: hypertension, proliferative diabetic retinopathy, proteins, aqueous humor

Translational Vision Science & Technology May 2021, Vol.10, 3. doi:https://doi.org/10.1167/tvst.10.6.3

Relating Retinal Vascular Oxygen Saturation and Microvasculature Morphology at Progressive Stages of Diabetic Retinopathy Open Access

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Selin L. Auvazian; Jennifer Cano; Sophie Leahy; Preny Karamian; Amir Kashani; Andrew Moshfeghi; Hossein Ameri; Norman P. Blair; Mahnaz Shahidi

Tags: diabetic retinopathy, language morphology, microvascular network, morphology, oxygen saturation measurement

Translational Vision Science & Technology May 2021, Vol.10, 4. doi:https://doi.org/10.1167/tvst.10.6.4

Development of a Web-Based Ensemble Machine Learning Application to Select the Optimal Size of Posterior Chamber Phakic Intraocular Lens Open Access

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Eun Min Kang; Ik Hee Ryu; Geunyoung Lee; Jin Kuk Kim; In Sik Lee; Ga Hee Jeon; Hojin Song; Kazutaka Kamiya; Tae Keun Yoo

Tags: datasets, internet, intraocular lens implant device, machine learning, postoperative care

Translational Vision Science & Technology May 2021, Vol.10, 5. doi:https://doi.org/10.1167/tvst.10.6.5

Longitudinal Study of Retinal Structure, Vascular, and Neuronal Function in Patients With Relapsing-Remitting Multiple Sclerosis: 1-Year Follow-Up Open Access

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Qi Chen; Hong Jiang; Silvia Delgado; Jeffrey Hernandez; Diego Eduardo Alba; Giovanni Gregori; Kottil W. Rammohan; Vittorio Porciatti; Jianhua Wang

Tags: follow-up, longitudinal studies, multiple sclerosis, relapsing-remitting, retina, eye

Translational Vision Science & Technology May 2021, Vol.10, 6. doi:https://doi.org/10.1167/tvst.10.6.6

Advanced Retinal Imaging and Ocular Parameters of the Rhesus Macaque Eye Open Access

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Kira H. Lin; Tu Tran; Soohyun Kim; Sangwan Park; J. Timothy Stout; Rui Chen; Jeffrey Rogers; Glenn Yiu; Sara Thomasy; Ala Moshiri

Tags: eye, macaca mulatta, retinal imaging, electroretinography

Translational Vision Science & Technology May 2021, Vol.10, 7. doi:https://doi.org/10.1167/tvst.10.6.7

Lactobacillus sakei Pro-Bio65 Reduces TNF-α Expression and Upregulates GSH Content and Antioxidant Enzymatic Activities in Human Conjunctival Cells Open Access

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Roberto Iorio; Sabrina Petricca; Carla Luzi; Pierangelo Bellio; Loredana Cristiano; Claudio Festuccia; Gianfranco Amicosante; Giuseppe Celenza

Tags: antioxidants, conjunctiva, lactobacillus sakei, tumor necrosis factors, mitochondria

Translational Vision Science & Technology May 2021, Vol.10, 8. doi:https://doi.org/10.1167/tvst.10.6.8

Focal Loss Analysis of Nerve Fiber Layer Reflectance for Glaucoma Diagnosis Open Access

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Ou Tan; Liang Liu; Qisheng You; Jie Wang; Aiyin Chen; Eliesa Ing; John C. Morrison; Yali Jia; David Huang

Tags: glaucoma, nerve fibers, eye

Translational Vision Science & Technology May 2021, Vol.10, 9. doi:https://doi.org/10.1167/tvst.10.6.9

Optogenetic Modulation of Intraocular Pressure in a Glucocorticoid-Induced Ocular Hypertension Mouse Model Open Access

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Tia J. Kowal; Philipp P. Prosseda; Ke Ning; Biao Wang; Jorge Alvarado; Brent E. Sendayen; Sayena Jabbehdari; W. Daniel Stamer; Yang Hu; Yang Sun

Tags: dexamethasone, glucocorticoids, intraocular pressure, mice, ocular hypertension

Translational Vision Science & Technology May 2021, Vol.10, 10. doi:https://doi.org/10.1167/tvst.10.6.10

A Baseline Score to Predict Response to Ranibizumab Treatment in Neovascular Age-Related Macular Degeneration Open Access

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Cheikh Diack; Dietmar Schwab; Valerie Cosson; Vincent Buchheit; Norman Mazer; Nicolas Frey

Tags: ranibizumab, exudative age-related macular degeneration

Translational Vision Science & Technology May 2021, Vol.10, 11. doi:https://doi.org/10.1167/tvst.10.6.11

Calibration of the Activity Inventory Item Bank: A Patient-Reported Outcome Measurement Instrument for Low Vision Rehabilitation Open Access

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Micaela Gobeille; Chris Bradley; Judith E. Goldstein; Robert Massof

Tags: blind rehabilitation therapy, calibration, patient self-report, mobility, reading (activity)

Translational Vision Science & Technology May 2021, Vol.10, 12. doi:https://doi.org/10.1167/tvst.10.6.12

Anterior Chamber Measurements in Healthy Children: A Cross-Sectional Study Using Optical Coherence Tomography Open Access

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Budor S. A. Edawaji; Irene Gottlob; Frank A. Proudlock

Tags: anterior chamber of eye, optical coherence tomography, well child, nose

Translational Vision Science & Technology May 2021, Vol.10, 13. doi:https://doi.org/10.1167/tvst.10.6.13

Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates Open Access

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Eduardo Rodríguez-Bocanegra; Fabian Wozar; Immanuel P. Seitz; Felix F. L. Reichel; Alex Ochakovski; Kirsten Bucher; Barbara Wilhelm; K. Ulrich Bartz-Schmidt; Tobias Peters; M. Dominik Fischer; for the RD-CURE Consortium

Tags: adeno-associated virus, eye, gene therapy, injections, primates

Translational Vision Science & Technology May 2021, Vol.10, 15. doi:https://doi.org/10.1167/tvst.10.6.15

Retinal Differential Light Sensitivity Variation Across the Macula in Healthy Subjects: Importance of Cone Separation and Loci Eccentricity Open Access

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Danuta M. Sampson; Danial Roshandel; Avenell L. Chew; Yufei Wang; Paul G. Stevenson; Matthew N. Cooper; Elaine Ong; Lawrence Wong; Jonathan La; David Alonso-Caneiro; Enid Chelva; Jane C. Khan; David D. Sampson; Fred K. Chen

Tags: macula lutea, photophobia, retinal cone, photon correlation spectroscopy

Translational Vision Science & Technology May 2021, Vol.10, 16. doi:https://doi.org/10.1167/tvst.10.6.16

Validating Ellipsoid Zone Area Measurement With Multimodal Imaging in Choroideremia Open Access

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Yi Zhai; Sarah Oke; Ian M. MacDonald

Tags: choroideremia, eye, face, multimodal imaging, photoreceptors

Translational Vision Science & Technology May 2021, Vol.10, 17. doi:https://doi.org/10.1167/tvst.10.6.17

Imaging Biomarkers of 1-Year Activity in Type 1 Macular Neovascularization Open Access

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Eliana Costanzo; Mariacristina Parravano; Daniela Giannini; Enrico Borrelli; Riccardo Sacconi; Giuseppe Querques

Tags: biological markers, diagnostic imaging, neovascularization, pathologic, spectral domain-optical coherence tomography

Translational Vision Science & Technology May 2021, Vol.10, 18. doi:https://doi.org/10.1167/tvst.10.6.18

Automatic Anterior Chamber Angle Classification Using Deep Learning System and Anterior Segment Optical Coherence Tomography Images Open Access

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Wanyue Li; Qian Chen; Chunhui Jiang; Guohua Shi; Guohua Deng; Xinghuai Sun

Tags: angle's classification, anterior chamber of eye, deep learning, optical coherence tomography, learning

Translational Vision Science & Technology May 2021, Vol.10, 19. doi:https://doi.org/10.1167/tvst.10.6.19

Feasibility Study of a Multimodal, Cloud-Based, Diabetic Retinal Screening Program in a Workplace Environment Open Access

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Jeffrey R. Willis; Ferhina S. Ali; Braelyn Argente; Amitha Domalpally; Jacqueline Gannon; Simon S. Gao; Shagun Grover; Purti Kanodia; Sparkle Russell-Puleri; Diana Sun; Cory Thrasher; Costas Tsougarakis; J. Jill Hopkins

Tags: diabetes mellitus, feasibility studies, retinal screening, workplace, vision

Translational Vision Science & Technology May 2021, Vol.10, 20. doi:https://doi.org/10.1167/tvst.10.6.20

Characterization of a Novel Caveolin Modulator That Reduces Vascular Permeability and Ocular Inflammation Open Access

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Pascal N. Bernatchez; Bo Tao; Ralph A. Bradshaw; David Eveleth; William C. Sessa

Tags: caveolins, electroconvulsive therapy, eye inflammation, inflammation, peptides

Translational Vision Science & Technology May 2021, Vol.10, 21. doi:https://doi.org/10.1167/tvst.10.6.21

Examining Whether AOSLO-Based Foveal Cone Metrics in Achromatopsia and Albinism Are Representative of Foveal Cone Structure Open Access

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Katie M. Litts; Erica N. Woertz; Niamh Wynne; Brian P. Brooks; Alicia Chacon; Thomas B. Connor, Jr.; Deborah Costakos; Alina Dumitrescu; Arlene V. Drack; Gerald A. Fishman; William W. Hauswirth; Christine N. Kay; Byron L. Lam; Michel Michaelides; Mark E. Pennesi; Kimberly E. Stepien; Sasha Strul; C. Gail Summers; Joseph Carroll

Tags: achromatopsia, albinism, retinal cone, diagnostic imaging, mosaicism

Translational Vision Science & Technology May 2021, Vol.10, 22. doi:https://doi.org/10.1167/tvst.10.6.22

Toxicity Threshold of Perfluorocarbon Liquids for Intraocular Use: Dose–Response Assessment of In Vitro Cytotoxicity of Possible Contaminants Open Access

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Mario Rosario Romano; Claudio Gatto; Laura Giurgola; Eugenio Ragazzi; Jana D'Amato Tóthová

Tags: cytotoxicity, fluorocarbons, liquids, toxic effect, patent foramen ovale

Translational Vision Science & Technology May 2021, Vol.10, 24. doi:https://doi.org/10.1167/tvst.10.6.24

Effect of High Myopia on Dynamic Changes of Anterior Angle After Pharmacologic Mydriasis in Cataract Patients: A SS-ASOCT Study Open Access

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Wei Wang; Jiaqing Zhang; Xiaoxun Gu; Xuhua Tan; Xiaoting Ruan; Guangyao Yang; Xiaoyun Chen; Guangming Jin; Lanhua Wang; Ye Dai; Zhenzhen Liu; Lixia Luo; Yizhi Liu

Tags: cataract, mydriasis, myopia, pharmacology, eye

Translational Vision Science & Technology May 2021, Vol.10, 25. doi:https://doi.org/10.1167/tvst.10.6.25

Quantification of Increased Corneal Subbasal Nerve Tortuosity in Dry Eye Disease and Its Correlation With Clinical Parameters Open Access

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Baikai Ma; Jianyang Xie; Tingting Yang; Pan Su; Rongjun Liu; Tong Sun; Yifan Zhou; Haiwei Wang; Xue Feng; Siyi Ma; Yitian Zhao; Hong Qi

Tags: cornea, dry eye syndromes, neurons

Translational Vision Science & Technology May 2021, Vol.10, 26. doi:https://doi.org/10.1167/tvst.10.6.26

Xeno- and Feeder-Free Differentiation of Human iPSCs to Trabecular Meshwork-Like Cells by Recombinant Cytokines Open Access

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Wenyan Wang; Yongzhen Miao; Shangru Sui; Yanan Wang; Shen Wu; Qilong Cao; Haoyun Duan; Xia Qi; Qingjun Zhou; Xiaojing Pan; Jingxue Zhang; Xuehong Chen; Yantao Han; Ningli Wang; Markus H. Kuehn; Wei Zhu

Tags: cytokine, culture media, conditioned, reverse transcriptase polymerase chain reaction

Translational Vision Science & Technology May 2021, Vol.10, 27. doi:https://doi.org/10.1167/tvst.10.6.27

Structure-Function Mapping Using a Three-Dimensional Neuroretinal Rim Parameter Derived From Spectral Domain Optical Coherence Tomography Volume Scans Open Access

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Ali Riza Cenk Celebi; Elli A. Park; Alice Chandra Verticchio Vercellin; Edem Tsikata; Ramon Lee; Eric Shieh; Hussein Antar; Madeline Freeman; Jing Zhang; Christian Que; Huseyin Simavli; Michael McClurkin; Rong Guo; Tobias Elze; Johannes F. de Boer; Teresa C. Chen

Tags: glaucoma, neuroretinal rim, spectral domain-optical coherence tomography, volume, visual fields

Translational Vision Science & Technology May 2021, Vol.10, 28. doi:https://doi.org/10.1167/tvst.10.6.28

Axial Length Change in Pseudophakic Eyes Measured by IOLMaster 700 Open Access

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Jiaqing Zhang; Zhenzhen Liu; Xiaozhang Qiu; Ling Jin; Lanhua Wang; Guangming Jin; Wei Wang; Xuhua Tan; Lixia Luo; Yizhi Liu

Tags: eye, cataract

Translational Vision Science & Technology May 2021, Vol.10, 29. doi:https://doi.org/10.1167/tvst.10.6.29

Automated Identification of Referable Retinal Pathology in Teleophthalmology Setting Open Access

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Qitong Gao; Joshua Amason; Scott Cousins; Miroslav Pajic; Majda Hadziahmetovic

Tags: datasets, pathology, training, diagnostic imaging

Translational Vision Science & Technology May 2021, Vol.10, 30. doi:https://doi.org/10.1167/tvst.10.6.30

A Simple Subjective Evaluation of Enface OCT Reflectance Images Distinguishes Glaucoma From Healthy Eyes Open Access

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Riccardo Cheloni; Simon D. Dewsbery; Jonathan Denniss

Tags: eye, glaucoma, retinal nerve fiber layer, optic disk

Translational Vision Science & Technology May 2021, Vol.10, 31. doi:https://doi.org/10.1167/tvst.10.6.31

Assessing the Clinical Utility of Expanded Macular OCTs Using Machine Learning Open Access

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Andrew C. Lin; Cecilia S. Lee; Marian Blazes; Aaron Y. Lee; Michael B. Gorin

Tags: machine learning, open-angle glaucoma, area under the roc curve, diagnostic imaging, datasets

Translational Vision Science & Technology May 2021, Vol.10, 32. doi:https://doi.org/10.1167/tvst.10.6.32

Generative Adversarial Network Based Automatic Segmentation of Corneal Subbasal Nerves on In Vivo Confocal Microscopy Images Open Access

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Erdost Yıldız; Abdullah Taha Arslan; Ayşe Yıldız Taş; Ali Faik Acer; Sertaç Demir; Afsun Şahin; Duygun Erol Barkana

Tags: cornea, microscopy, confocal, neurons, noise, diagnostic imaging

Translational Vision Science & Technology May 2021, Vol.10, 33. doi:https://doi.org/10.1167/tvst.10.6.33

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