Volume 11 Issue 2 | TVST

Comparative Assessment of Retinal Blood Flow Velocity Changes Following Brimonidine and Brinzolamide Administration Using Retinal Function Imaging Open Access

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Tim J. Enz; Mario Bittner; James R. Tribble; Pete A. Williams; Michael A. Thiel; Martin K. Schmid; Lucas M. Bachmann; Frank Bochmann

Tags: blood flow velocity, brimonidine, brinzolamide ophthalmic suspension, diagnostic imaging, intraocular pressure

Translational Vision Science & Technology February 2022, Vol.11, 1. doi:https://doi.org/10.1167/tvst.11.2.1

Hydrodynamic Interaction Between Tear Film and Air Puff From Noncontact Tonometry Open Access

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Atieh Yousefi; Yanhui Ma; Cynthia J. Roberts; Sayoko E. Moroi; Matthew A. Reilly

Tags: eyedrops, non-contact tonometry, tear film finding

Translational Vision Science & Technology February 2022, Vol.11, 2. doi:https://doi.org/10.1167/tvst.11.2.2

Physicochemical Properties of Explanted Silicone Oil After Use as an Intraocular Tamponade Open Access

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Maximilian Hammer; Sonja Schickhardt; Donald J. Munro; Alexander Scheuerle; Christian S. Mayer; Gerd U. Auffarth

Tags: emulsions, silicone oils, viscosity, surface tension

Translational Vision Science & Technology February 2022, Vol.11, 3. doi:https://doi.org/10.1167/tvst.11.2.3

A Blood Protein Signature Stratifies Clinical Response to csDMARD Therapy in Pediatric Uveitis Open Access

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Roos A. W. Wennink; Viera Kalinina Ayuso; Weiyang Tao; Eveline M. Delemarre; Joke H. de Boer; Jonas J. W. Kuiper

Tags: blood proteins, child, proteins, uveitis, uveitis, pediatric

Translational Vision Science & Technology February 2022, Vol.11, 4. doi:https://doi.org/10.1167/tvst.11.2.4

Clustered Volleys Stimulus Presentation for Multifocal Objective Perimetry Open Access

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Corinne F. Carle; Andrew C. James; Faran Sabeti; Maria Kolic; Rohan W. Essex; Chris Shean; Rhiannon Jeans; Aiasha Saikal; Alice Licinio; Ted Maddess

Tags: cerebral vasospasm, chorionic villi sampling, cyclical vomiting syndrome, perimetry, pupil

Translational Vision Science & Technology February 2022, Vol.11, 5. doi:https://doi.org/10.1167/tvst.11.2.5

Diagnosis of Polypoidal Choroidal Vasculopathy From Fluorescein Angiography Using Deep Learning Open Access

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Yu-Yeh Tsai; Wei-Yang Lin; Shih-Jen Chen; Paisan Ruamviboonsuk; Cheng-Ho King; Chia-Ling Tsai

Tags: attention, choroidal neovascularization, deep learning, fluorescein angiography, polypoidal choroidal vasculopathy

Translational Vision Science & Technology February 2022, Vol.11, 6. doi:https://doi.org/10.1167/tvst.11.2.6

Validation of the Symptom Questionnaire for Visual Dysfunctions (SQVD): A Questionnaire to Evaluate Symptoms of any Type of Visual Dysfunctions Open Access

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Pilar Cacho-Martínez; Mario Cantó-Cerdán; Francisco Lara-Lacárcel; Ángel García-Muñoz

Tags: questionnaires, reliability, signs and symptoms, vision disorders

Translational Vision Science & Technology February 2022, Vol.11, 7. doi:https://doi.org/10.1167/tvst.11.2.7

Targeting NECTIN-1 Based on CRISPR/Cas9 System Attenuated the Herpes Simplex Virus Infection in Human Corneal Epithelial Cells In Vitro Open Access

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Yue Li; Yuda Wei; Gang Li; Shiqian Huang; Jianjiang Xu; Qiurong Ding; Jiaxu Hong

Tags: crispr, herpes simplex infection, nectins, corneal epithelial cells, attenuation

Translational Vision Science & Technology February 2022, Vol.11, 8. doi:https://doi.org/10.1167/tvst.11.2.8

Retinal Oxygen Delivery and Extraction in Ophthalmologically Healthy Subjects With Different Blood Pressure Status Open Access

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Konstantinos Pappelis; Nomdo M. Jansonius

Tags: blood pressure, did not receive therapy or drug, hypotension, oxygen delivery, eye

Translational Vision Science & Technology February 2022, Vol.11, 9. doi:https://doi.org/10.1167/tvst.11.2.9

Prevalence of Choroidal Abnormalities and Lisch Nodules in Children Meeting Clinical and Molecular Diagnosis of Neurofibromatosis Type 1 Open Access

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Mariana Flores Pimentel; Anna Heath; Michael J. Wan; Rowaida Hussein; Kate E. Leahy; Heather MacDonald; Erika Tavares; Cynthia VandenHoven; Katelyn MacNeill; Peter Kannu; Patricia C. Parkin; Elise Heon; Arun Reginald; Ajoy Vincent

Tags: child, eye manifestations, lesch-nyhan syndrome, lisch nodules, neurofibromatosis 1

Translational Vision Science & Technology February 2022, Vol.11, 10. doi:https://doi.org/10.1167/tvst.11.2.10

Development of a β-Variational Autoencoder for Disentangled Latent Space Representation of Anterior Segment Optical Coherence Tomography Images Open Access

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Kilhwan Shon; Kyung Rim Sung; Jiehoon Kwak; Joong Won Shin; Joo Yeon Lee

Tags: anterior chamber of eye, learning, optical coherence tomography, reconstructive surgical procedures, venous air embolism

Translational Vision Science & Technology February 2022, Vol.11, 11. doi:https://doi.org/10.1167/tvst.11.2.11

Sex Differences in RANTES (CCL5) in Patients With Intermediate Age-Related Macular Degeneration (AMD) and Controls With no AMD Open Access

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Cheryl N. Fonteh; Alan G. Palestine; Brandie D. Wagner; Jennifer L. Patnaik; Marc T. Mathias; Naresh Mandava; Rebecca Baldermann; Anne M. Lynch; for the University of Colorado Retina Research Group

Tags: age-related macular degeneration, rantes, sex characteristics

Translational Vision Science & Technology February 2022, Vol.11, 12. doi:https://doi.org/10.1167/tvst.11.2.12

Prospective, Randomized, Contralateral Eye Comparison of Functional Optical Zone, and Visual Quality After SMILE and FS-LASIK for High Myopia Open Access

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Shengyu He; Yiqi Luo; Pei Chen; Yiming Ye; Hua Zheng; Min Lan; Jing Zhuang; Keming Yu

Tags: eye, keratomileusis, laser in situ, myopia, optics, contrast sensitivity

Translational Vision Science & Technology February 2022, Vol.11, 13. doi:https://doi.org/10.1167/tvst.11.2.13

Measurement Properties of the Attitudes to Gene Therapy for the Eye (AGT-Eye) Instrument for People With Inherited Retinal Diseases Open Access

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Myra B. McGuinness; Alexis Ceecee Britten-Jones; Lauren N. Ayton; Robert P. Finger; Fred K. Chen; John Grigg; Heather G. Mack

Tags: attitude, eye, gene therapy, retinal diseases, perception

Translational Vision Science & Technology February 2022, Vol.11, 14. doi:https://doi.org/10.1167/tvst.11.2.14

A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers’ Serum on RPE Cells With AMD High-Risk Alleles Open Access

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Bincui Cai; Zhe Zhang; Shuo Sun; Tingting Lin; Yifeng Ke; Zhiqing Li; Jin Yang; Xiaorong Li

Tags: alleles, caveolins, cigarettes, environmental factors, proteomics

Translational Vision Science & Technology February 2022, Vol.11, 15. doi:https://doi.org/10.1167/tvst.11.2.15

Rates of Glaucoma Progression Derived from Linear Mixed Models Using Varied Random Effect Distributions Open Access

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Swarup S. Swaminathan; Samuel I. Berchuck; Alessandro A. Jammal; J. Sunil Rao; Felipe A. Medeiros

Tags: eye, glaucoma, visual fields

Translational Vision Science & Technology February 2022, Vol.11, 16. doi:https://doi.org/10.1167/tvst.11.2.16

Prospective Pilot Clinical Study of Noninvasive Cerebrovascular Autoregulation Monitoring in Open-Angle Glaucoma Patients and Healthy Subjects Open Access

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Yasin Hamarat; Mantas Deimantavicius; Vilius Dambrauskas; Vaidas Labunskas; Vilma Putnynaite; Paulius Lucinskas; Lina Siaudvytyte; Evelina Simiene; Akvile Stoskuviene; Ingrida Januleviciene; Vytautas Petkus; Arminas Ragauskas

Tags: cerebral blood flow, glaucoma, open-angle glaucoma

Translational Vision Science & Technology February 2022, Vol.11, 17. doi:https://doi.org/10.1167/tvst.11.2.17

Change in Corneal Power Distribution in Orthokeratology: A Predictor for the Change in Axial Length Open Access

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Zhe Zhang; Zhi Chen; Zhuoyi Chen; Jiaqi Zhou; Li Zeng; Feng Xue; Xiaomei Qu; Xingtao Zhou

Tags: cornea, menopause, orthokeratology, lens (device)

Translational Vision Science & Technology February 2022, Vol.11, 18. doi:https://doi.org/10.1167/tvst.11.2.18

The Role of Survivin and Transcription Factor FOXP1 in Scarring After Glaucoma Surgery Open Access

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Xiaocong Wang; Zhihua Huang; Lan Zeng; Xin Jin; Ai Yan; Ying Zhang; Wei Tan

Tags: cicatrix, survivin, transcription factor, glaucoma surgery

Translational Vision Science & Technology February 2022, Vol.11, 19. doi:https://doi.org/10.1167/tvst.11.2.19

The Frontloading Fields Study: The Impact of False Positives and Seeding Point Errors on Visual Field Reliability When Using SITA-Faster Open Access

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Jack Phu; Michael Kalloniatis

Tags: false-positive results, reliability, visual fields

Translational Vision Science & Technology February 2022, Vol.11, 20. doi:https://doi.org/10.1167/tvst.11.2.20

Axial Stretching of Vessels in the Retinal Vascular Plexus With 3D OCT-Angiography Open Access

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Julian Johannes Kuhlmann; Kai Rothaus; Xiaoyi Jiang; Britta Heimes-Bussmann; Henrik Faatz; Marius Book; Daniel Pauleikhoff

Tags: angiogram, stretching exercises, voxel, vasculature

Translational Vision Science & Technology February 2022, Vol.11, 21. doi:https://doi.org/10.1167/tvst.11.2.21

Application of Deep Learning Methods for Binarization of the Choroid in Optical Coherence Tomography Images Open Access

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Joshua Muller; David Alonso-Caneiro; Scott A. Read; Stephen J. Vincent; Michael J. Collins

Tags: choroid, datasets, deep learning, optical coherence tomography, pixel

Translational Vision Science & Technology February 2022, Vol.11, 23. doi:https://doi.org/10.1167/tvst.11.2.23

Implementation of an Online Glaucoma-Specific Quality of Life Computerized Adaptive Test System in a US Glaucoma Hospital Open Access

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Eva K. Fenwick; Ana M. Roldan; Omar A. Halawa; Ryan S. Meshkin; Nazlee Zebardast; Vesselin Popov; Przemysław Lis; David S. Friedman; Ecosse L. Lamoureux

Tags: glaucoma, hospitals, quality of life, physicians

Translational Vision Science & Technology February 2022, Vol.11, 24. doi:https://doi.org/10.1167/tvst.11.2.24

Bleb Analysis Using Anterior Segment Optical Coherence Tomography and Surgical Predictors of XEN Gel Stent Open Access

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Yuri Kim; Su-Ho Lim; Seungsoo Rho

Tags: blister, gel, surgical procedures, operative, stents, optical coherence tomography

Translational Vision Science & Technology February 2022, Vol.11, 26. doi:https://doi.org/10.1167/tvst.11.2.26

Validation of the Modified Schein Dry Eye Symptom Questionnaire and Comparison With the Ocular Surface Disease Index Open Access

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Jerry R. Paugh; Elaine Chen; Justin Kwan; Tiffany Nguyen; Alan Sasai; Melinda Thomas De Jesus; Andrew Loc Nguyen; Michael T. Christensen; David Meadows

Tags: dry eye syndromes, questionnaires, signs and symptoms, ocular surfaces

Translational Vision Science & Technology February 2022, Vol.11, 27. doi:https://doi.org/10.1167/tvst.11.2.27

Thickness of the Protective Layers of Different Ophthalmic Viscosurgical Devices During Lens Surgery in a Porcine Model Open Access

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Melanie Wüst; Philipp Matten; Magdalena Nenning; Oliver Findl

Tags: eye, lens (device), lens, crystalline, suidae, surgical procedures, operative

Translational Vision Science & Technology February 2022, Vol.11, 28. doi:https://doi.org/10.1167/tvst.11.2.28

Comparison of 16S rDNA Amplicon Sequencing With the Culture Method for Diagnosing Causative Pathogens in Bacterial Corneal Infections Open Access

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Na An; Changhao Wang; Xiuhong Dou; Xianning Liu; Jie Wu; Yan Cheng

Tags: corneal infections, dna, ribosomal, pathogenic organism, recombinant dna

Translational Vision Science & Technology February 2022, Vol.11, 29. doi:https://doi.org/10.1167/tvst.11.2.29

HL3501, a Novel Selective A3 Adenosine Receptor Antagonist, Lowers Intraocular Pressure (IOP) in Animal Glaucoma Models Open Access

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Yunhee Kim; Jaewook Yang; Jee Young Kim; Jang Mi Lee; Woo Chan Son; Byoung-Gon Moon

Tags: adenosine receptor antagonists, glaucoma, intraocular pressure, mice, oryctolagus cuniculus

Translational Vision Science & Technology February 2022, Vol.11, 30. doi:https://doi.org/10.1167/tvst.11.2.30

PNP Hydrogel Prevents Formation of Symblephara in Mice After Ocular Alkali Injury Open Access

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Aditi Swarup; Abigail K. Grosskopf; Lindsay M. Stapleton; Varun R. Subramaniam; BaoXiang Li; Irving L. Weissman; Eric A. Appel; Albert Y. Wu

Tags: alkalies, hydrogel, mice, wounds and injuries

Translational Vision Science & Technology February 2022, Vol.11, 31. doi:https://doi.org/10.1167/tvst.11.2.31

Early Three-Dimensional Intrableb Structural Changes in Primary-Open Angle Glaucoma and Exfoliation Glaucoma After Ex-PRESS Surgery Open Access

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Ikki Sugimoto; Shinichi Usui; Tomoyuki Okazaki; Rumi Kawashima; Atsuya Miki; Ryo Kawasaki; Kenji Matsushita; Kohji Nishida

Tags: blister, glaucoma, intraocular pressure, surgical procedures, operative, exfoliation syndrome

Translational Vision Science & Technology February 2022, Vol.11, 32. doi:https://doi.org/10.1167/tvst.11.2.32

Effect of Physiological Oxygen on Primary Human Corneal Endothelial Cell Cultures Open Access

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Sangita P. Patel; Brayan Calle Gonzalez; Nataliia Paone; Christian Mueller; Jamie C. Floss; Maria E. Sousa; Michael Y. Shi

Tags: cornea, endothelial cells, oxygen, donors

Translational Vision Science & Technology February 2022, Vol.11, 33. doi:https://doi.org/10.1167/tvst.11.2.33

Developing a Screening Tool for Areas of Abnormal Central Vision Using Visual Stimuli With Natural Scene Statistics Open Access

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Rekha Srinivasan; Andrew Turpin; Allison M. McKendrick

Tags: glaucoma, natural scenes, photic stimulation, screening, vision

Translational Vision Science & Technology February 2022, Vol.11, 34. doi:https://doi.org/10.1167/tvst.11.2.34

Characterizing Fixational Eye Motion Variance Over Time as Recorded by the Tracking Scanning Laser Ophthalmoscope Open Access

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Shivany Y. Condor Montes; Daniel Bennett; Ethan Bensinger; Lakshmisahithi Rani; Younes Sherkat; Chao Zhao; Zachary Helft; Austin Roorda; Ari J. Green; Christy K. Sheehy

Tags: eye, heterogeneity of variance, lasers, motion, ophthalmoscopes

Translational Vision Science & Technology February 2022, Vol.11, 35. doi:https://doi.org/10.1167/tvst.11.2.35

Abnormal Appearance of the Area Centralis in Labrador Retrievers With an ABCA4 Loss-of-function Mutation Open Access

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Björn Ekesten; Suvi Mäkeläinen; Stuart Ellis; Ulrika Kjellström; Tomas F. Bergström

Tags: abca4 gene, dog, domestic, fovea centralis, likelihood ratio, loss of function mutation

Translational Vision Science & Technology February 2022, Vol.11, 36. doi:https://doi.org/10.1167/tvst.11.2.36

Choriocapillaris Changes in Myopic Macular Degeneration Open Access

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Jonathan Li; Hao Zhou; Max Feinstein; Jessica Wong; Ruikang K. Wang; Lawrence Chan; Yining Dai; Travis Porco; Jacque L. Duncan; Daniel M. Schwartz

Tags: chief complaint, fluid flow, myopic macular degeneration, eye, chorioretinal atrophy

Translational Vision Science & Technology February 2022, Vol.11, 37. doi:https://doi.org/10.1167/tvst.11.2.37

Application of Artificial Intelligence and Deep Learning for Choroid Segmentation in Myopia Open Access

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Hung-Ju Chen; Yu-Len Huang; Siu-Lun Tse; Wei-Ping Hsia; Chung-Hao Hsiao; Yang Wang; Chia-Jen Chang

Tags: artificial intelligence, choroid, deep learning, myopia, datasets

Translational Vision Science & Technology February 2022, Vol.11, 38. doi:https://doi.org/10.1167/tvst.11.2.38

A Deep Learning Algorithm for Classifying Diabetic Retinopathy Using Optical Coherence Tomography Angiography Open Access

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Gahyung Ryu; Kyungmin Lee; Donggeun Park; Inhye Kim; Sang Hyun Park; Min Sagong

Tags: angiogram, deep learning, diabetic retinopathy, machine learning, optical coherence tomography

Translational Vision Science & Technology February 2022, Vol.11, 39. doi:https://doi.org/10.1167/tvst.11.2.39

Preliminary Evaluation of a Smartphone App for Refractive Error Measurement Open Access

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Gang Luo; Chen-Yuan Lee; Prerana Shivshanker; Wenbo Cheng; Jamie Wang; Sophia Marusic; Aparna Raghuram; Yan Jiang; Rui Liu

Tags: cell phones, mobile applications, refractive errors, refraction, eye

Translational Vision Science & Technology February 2022, Vol.11, 40. doi:https://doi.org/10.1167/tvst.11.2.40

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