Volume 11 Issue 10 | TVST

Artificial Intelligence

Deep Learning Segmentation, Visualization, and Automated 3D Assessment of Ciliary Body in 3D Ultrasound Biomicroscopy Images Open Access

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Ahmed Tahseen Minhaz; Duriye Damla Sevgi; Sunwoo Kwak; Alvin Kim; Hao Wu; Richard W. Helms; Mahdi Bayat; David L. Wilson; Faruk H. Orge

Tags: ciliary body, deep learning, 3d ultrasound, ultrasound biomicroscopy, ciliary muscle

Translational Vision Science & Technology October 2022, Vol.11, 3. doi:https://doi.org/10.1167/tvst.11.10.3

A Framework for Automating Psychiatric Distress Screening in Ophthalmology Clinics Using an EHR-Derived AI Algorithm Open Access

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Samuel I. Berchuck; Alessandro A. Jammal; David Page; Tamara J. Somers; Felipe A. Medeiros

Tags: electronic medical records, ophthalmology, psychiatry, screening

Translational Vision Science & Technology October 2022, Vol.11, 6. doi:https://doi.org/10.1167/tvst.11.10.6

Synthetic OCT Data Generation to Enhance the Performance of Diagnostic Models for Neurodegenerative Diseases Open Access

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Hajar Danesh; David H. Steel; Jeffry Hogg; Fereshteh Ashtari; Will Innes; Jaume Bacardit; Anya Hurlbert; Jenny C. A. Read; Rahele Kafieh

Tags: maps, neurodegenerative disorders, neuromyelitis optica, training, histogram

Translational Vision Science & Technology October 2022, Vol.11, 10. doi:https://doi.org/10.1167/tvst.11.10.10

Application of Deep Learning for Automated Detection of Polypoidal Choroidal Vasculopathy in Spectral Domain Optical Coherence Tomography Open Access

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Papis Wongchaisuwat; Ranida Thamphithak; Peerakarn Jitpukdee; Nida Wongchaisuwat

Tags: deep learning, polypoidal choroidal vasculopathy, spectral domain-optical coherence tomography

Translational Vision Science & Technology October 2022, Vol.11, 16. doi:https://doi.org/10.1167/tvst.11.10.16

Characterization of the Retinal Microvasculature and FAZ Changes in Ischemic Stroke and Its Different Types Open Access

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Hongyu Duan; Jianyang Xie; Yifan Zhou; Hui Zhang; Yiyun Liu; Chuhao Tang; Yitian Zhao; Hong Qi

Tags: ischemic stroke, retinal vasculature

Translational Vision Science & Technology October 2022, Vol.11, 21. doi:https://doi.org/10.1167/tvst.11.10.21

Predictive Modeling of Long-Term Glaucoma Progression Based on Initial Ophthalmic Data and Optic Nerve Head Characteristics Open Access

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Eun Ji Lee; Tae-Woo Kim; Jeong-Ah Kim; Seung Hyen Lee; Hyunjoong Kim

Tags: eye, glaucoma, optic disk, retinal nerve fiber layer, intraocular pressure

Translational Vision Science & Technology October 2022, Vol.11, 24. doi:https://doi.org/10.1167/tvst.11.10.24

Deep Ensemble Learning for Retinal Image Classification Open Access

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Edward Ho; Edward Wang; Saerom Youn; Asaanth Sivajohan; Kevin Lane; Jin Chun; Cindy M. L. Hutnik

Tags: area under the roc curve, datasets, learning, screening, training

Translational Vision Science & Technology October 2022, Vol.11, 39. doi:https://doi.org/10.1167/tvst.11.10.39

Deep Learning-Based Modeling of the Dark Adaptation Curve for Robust Parameter Estimation Open Access

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Tharindu De Silva; Kristina Hess; Peyton Grisso; Alisa T. Thavikulwat; Henry Wiley; Tiarnan D. L. Keenan; Emily Y. Chew; Brett G. Jeffrey; Catherine A. Cukras

Tags: dark adaptation, fitting curve to data, learning, neutrophil/lymphocyte ratio, retinal cone

Translational Vision Science & Technology October 2022, Vol.11, 40. doi:https://doi.org/10.1167/tvst.11.10.40

Cornea & External Disease

The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation Open Access

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Tsung-Chuan Ho; Nai-Wen Fan; Shu-I Yeh; Show-Li Chen; Yeou-Ping Tsao

Tags: dry eye syndromes, gelatinase b, inflammation, mice, peptides

Translational Vision Science & Technology October 2022, Vol.11, 12. doi:https://doi.org/10.1167/tvst.11.10.12

Corneal Neuro-Regenerative Effect of Transcutaneous Electrical Stimulation in Rabbit Lamellar Keratectomy Model Open Access

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Young-Sik Yoo; Sera Park; Pyeonghwa Eun; Young Min Park; Dong Hui Lim; Tae-Young Chung

Tags: cornea, electric stimulation, keratectomy, oryctolagus cuniculus, superior limbic keratoconjunctivitis

Translational Vision Science & Technology October 2022, Vol.11, 17. doi:https://doi.org/10.1167/tvst.11.10.17

In Situ-Forming Collagen-Hyaluronate Semi-Interpenetrating Network Hydrogel Enhances Corneal Defect Repair Open Access

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Fang Chen; David C. Mundy; Peter Le; Youngyoon Amy Seo; Caitlin M. Logan; Gabriella Maria Fernandes-Cunha; Chris A. Basco; David Myung

Tags: collagen, cornea, hydrogel, hydrogels, gel

Translational Vision Science & Technology October 2022, Vol.11, 22. doi:https://doi.org/10.1167/tvst.11.10.22

Feasibility of Magnetic Levator Prosthesis Frame Customization Using Craniofacial Scans and 3-D Printing Open Access

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Kevin E. Houston; Eleftherios I. Paschalis

Tags: benchmarking, eye, magnets, printing, three-dimensional, prostheses

Translational Vision Science & Technology October 2022, Vol.11, 34. doi:https://doi.org/10.1167/tvst.11.10.34

Glaucoma

Aqueous Humor Growth Factor Levels and Trabeculectomy Outcomes in Primary Open-Angle Glaucoma Patients: A 2-Year Prospective Study Open Access

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Tianwei Qian; Mingshui Fu; Luyao Ye; Jingxiao Du; Xun Xu; Zhihua Zhang

Tags: aqueous humor, fibroblast growth factor 1, growth factor, open-angle glaucoma, prospective studies

Translational Vision Science & Technology October 2022, Vol.11, 2. doi:https://doi.org/10.1167/tvst.11.10.2

Relationship Between Deep Retinal Macular Vessel Density and Bipolar Cell Function in Glaucomatous Eyes Open Access

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Yuji Yoshikawa; Takuhei Shoji; Junji Kanno; Hirokazu Ishii; Minami Chino; Yuro Igawa; Kei Shinoda; Yozo Miyake

Tags: eye, glaucoma, macular vasculature, retinal bipolar cells

Translational Vision Science & Technology October 2022, Vol.11, 4. doi:https://doi.org/10.1167/tvst.11.10.4

Corvis Biomechanical Factor Facilitates the Detection of Primary Angle Closure Glaucoma Open Access

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Chien-Chih Chou; Po-Jen Shih; Chun-Yuan Wang; Tzuu-Shuh Jou; Jun-Peng Chen; I-Jong Wang

Tags: angle closure glaucoma, cornea

Translational Vision Science & Technology October 2022, Vol.11, 7. doi:https://doi.org/10.1167/tvst.11.10.7

Moving Stimulus Perimetry: A New Functional Test for Glaucoma Open Access

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Stuart K. Gardiner; Steven L. Mansberger

Tags: dynamic range, glaucoma screening, perimetry, glaucoma, visual fields

Translational Vision Science & Technology October 2022, Vol.11, 9. doi:https://doi.org/10.1167/tvst.11.10.9

Glaucoma Diagnostic Performance of Retinal Blood Flow Measurement With Doppler Optical Coherence Tomography Open Access

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Tsubasa Abe; Takafumi Yoshioka; Youngseok Song; Tomofumi Tani; Motofumi Kawai; Tsuneaki Omae; Kengo Takahashi; Yoshitaka Takizawa; Tomoko Ro-Mase; Satoshi Ishiko; Kana Minamide; Jun Sakai; Masahiro Akiba; Yohei Hashimoto; Akitoshi Yoshida

Tags: glaucoma, optical coherence tomography, vascular flow, eye

Translational Vision Science & Technology October 2022, Vol.11, 11. doi:https://doi.org/10.1167/tvst.11.10.11

Association of Ambulatory Blood Pressure and Other Factors With Intraocular Pressure–Related 24-Hour Contact Lens Sensor Profile in Untreated Glaucoma Open Access

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Kazuki Nakazawa; Tomomi Higashide; Shunsuke Tsuchiya; Satomi Shioya; Masahiko Okayama; Kazuhisa Sugiyama

Tags: ambulatory blood pressure monitoring, blood pressure, contact lenses, did not receive therapy or drug, glaucoma

Translational Vision Science & Technology October 2022, Vol.11, 18. doi:https://doi.org/10.1167/tvst.11.10.18

Time–Frequency Analysis of ERG With Discrete Wavelet Transform and Matching Pursuits for Glaucoma Open Access

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Marc Sarossy; Jonathan Crowston; Dinesh Kumar; Anne Weymouth; Zhichao Wu

Tags: electroretinography, erg protein, human, glaucoma, pursuit eye movement

Translational Vision Science & Technology October 2022, Vol.11, 19. doi:https://doi.org/10.1167/tvst.11.10.19

The Topographic Relationship Between Choroidal Microvascular Dropout and Glaucomatous Damage in Primary Angle-Closure Glaucoma Open Access

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Li Tan; Di Ma; Junren He; Hongxi Wang; Shirong Chen; Yongdong Lin

Tags: angle closure glaucoma, glaucoma, retinal nerve fiber layer, eye

Translational Vision Science & Technology October 2022, Vol.11, 20. doi:https://doi.org/10.1167/tvst.11.10.20

Repurposing Antihypertensive Drugs for the Prevention of Glaucoma: A Mendelian Randomization Study Open Access

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Jingjing Liu; Shuang Li; Yang Hu; Shizheng Qiu

Tags: antihypertensive agents, glaucoma, mendelian randomization analysis, prevention, intraocular pressure

Translational Vision Science & Technology October 2022, Vol.11, 32. doi:https://doi.org/10.1167/tvst.11.10.32

Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals Open Access

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Georgina L. Hollitt; Owen M. Siggs; Bronwyn Ridge; Miriam C. Keane; David A. Mackey; Stuart MacGregor; Alex W. Hewitt; Jamie E. Craig; Emmanuelle Souzeau

Tags: genetic risk, glaucoma, attitude

Translational Vision Science & Technology October 2022, Vol.11, 38. doi:https://doi.org/10.1167/tvst.11.10.38

Low Vision Rehabilitation

Using Electronic Clinical Decision Support to Examine Vision Rehabilitation Referrals and Practice Guidelines in Ophthalmology Open Access

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Judith E. Goldstein; Xinxing Guo; Bonnielin K. Swenor; Michael V. Boland; Kerry Smith

Tags: blind rehabilitation therapy, ophthalmologists, ophthalmology, patient referral, practice guidelines

Translational Vision Science & Technology October 2022, Vol.11, 8. doi:https://doi.org/10.1167/tvst.11.10.8

Pediatric Ophthalmology & Strabismus

Validation of the PowerRef 3 for Measuring Accommodation: Comparison With the Grand Seiko WAM-5500A Autorefractor Open Access

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Alyssa M. Gehring; Jennifer X. Haensel; Molly K. Curtiss; Tawna L. Roberts

Tags: visual accommodation, eye, meridians

Translational Vision Science & Technology October 2022, Vol.11, 25. doi:https://doi.org/10.1167/tvst.11.10.25

Ocular Perfusion Pressure in 7- and 12-Year-Old Chinese Children: The Anyang Childhood Eye Study Open Access

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Wei-Ling Bai; Yu-Ting Kang; Shi-Ming Li; Jia-He Gan; Shi-Fei Wei; Meng-Tian Kang; Yun-Yun Sun; Ming-Hao Sun; He Li; Feng-Ju Zhang; Ning-Li Wang

Tags: child, chinese (other dialects), chinese people, eye, mopp protocol

Translational Vision Science & Technology October 2022, Vol.11, 26. doi:https://doi.org/10.1167/tvst.11.10.26

Retina

A Long-Term Safety and Efficacy Report on Intravitreal Delivery of Adipose Stem Cells and Secretome on Visual Deficits After Traumatic Brain Injury Open Access

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Pratheepa Kumari Rasiah; Kumar Abhiram Jha; Jordy Gentry; Nobel A. Del Mar; Tanisha Townsend; Kwame E. Torgbe; Anton Reiner; Rajashekhar Gangaraju

Tags: ambulatory surgery center, blast injuries, eye, intravitreal injections, mice

Translational Vision Science & Technology October 2022, Vol.11, 1. doi:https://doi.org/10.1167/tvst.11.10.1

Hemodynamic Effects of Anti-Vascular Endothelial Growth Factor Injections on Optical Coherence Tomography Angiography in Diabetic Macular Edema Eyes Open Access

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Jessica Song; Bonnie B. Huang; Janice X. Ong; Nicholas Konopek; Amani A. Fawzi

Tags: angiogram, anti-vascular endothelial growth factor therapy, diabetic macular edema, endothelial growth factors, eye

Translational Vision Science & Technology October 2022, Vol.11, 5. doi:https://doi.org/10.1167/tvst.11.10.5

Measurement of the Macular Hole Diameter by En Face Slab Optical Coherence Tomography Reflectance Imaging Open Access

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Yuna Uechi; Kentaro Nakamura; Masato Shinozuka; Shohei Kawasaki; Kazuyoshi Okawa; Tatsuya Inoue; Ryo Asaoka; Maiko Maruyama-Inoue; Yasuo Yanagi; Kazuaki Kadonosono

Tags: diagnostic imaging, face, macular holes, optical coherence tomography, postoperative care

Translational Vision Science & Technology October 2022, Vol.11, 13. doi:https://doi.org/10.1167/tvst.11.10.13

Impact of the Aging Lens and Posterior Capsular Opacification on Quantitative Autofluorescence Imaging in Age-Related Macular Degeneration Open Access

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Andreas Berlin; Mark E. Clark; Thomas A. Swain; Nathan A. Fischer; Gerald McGwin, Jr; Kenneth R. Sloan; Cynthia Owsley; Christine A. Curcio

Tags: age-related macular degeneration, aging, autofluorescence, diagnostic imaging, eye

Translational Vision Science & Technology October 2022, Vol.11, 23. doi:https://doi.org/10.1167/tvst.11.10.23

Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema Open Access

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Nicholas J. Agard; Gu Zhang; John Ridgeway; Danielle M. Dicara; Phillip Y. Chu; Rachana Ohri; Sarah Sanowar; Jean-Michel Vernes; Hannah Chi; Jiameng Zhang; Emily Holz; Maciej Paluch; Guannan He; Yingjia Benson; Jianhuan Zhang; Pamela Chan; Nga Tang; Prachi Javale; Blair Wilson; Kathy Barrett; Rebecca K. Rowntree; Julie Hang; Y. Gloria Meng; Phil Hass; Germaine Fuh; Robert Piskol; Vladimir Bantseev; Kelly M. Loyet; John C. Tran; Cong Wu; Vahan B. Indjeian; Vittal Shivva; Minhong Yan

Tags: agonists, diabetic macular edema, vasculature, antibodies

Translational Vision Science & Technology October 2022, Vol.11, 27. doi:https://doi.org/10.1167/tvst.11.10.27

Degeneration of Melanin-Containing Structures Observed Longitudinally in the Eyes of SOD1^−/− Mice Using Intensity, Polarization, and Spectroscopic OCT Open Access

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Conrad W. Merkle; Marco Augustin; Danielle J. Harper; Martin Glösmann; Bernhard Baumann

Tags: depolarization, eye, melanins, mice, sod1 gene

Translational Vision Science & Technology October 2022, Vol.11, 28. doi:https://doi.org/10.1167/tvst.11.10.28

Evaluation of Molecular Properties versus In Vivo Performance of Aflibercept, Brolucizumab, and Ranibizumab in a Retinal Vascular Hyperpermeability Model Open Access

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William Schubert; Carsten Terjung; Ashique Rafique; Carmelo Romano; Philipp Ellinger; Kay D. Rittenhouse

Tags: aflibercept, brolucizumab, oryctolagus cuniculus, ranibizumab, vascular endothelial growth factor a

Translational Vision Science & Technology October 2022, Vol.11, 36. doi:https://doi.org/10.1167/tvst.11.10.36

Danicopan, an Oral Complement Factor D Inhibitor, Exhibits High and Sustained Exposure in Ocular Tissues in Preclinical Studies Open Access

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David D. Boyer; Ya-Ping Ko; Steven D. Podos; Mark E. Cartwright; Xiang Gao; Jason A. Wiles; Mingjun Huang

Tags: body tissue, complement factor d, melanins, oryctolagus cuniculus, pre-clinical research

Translational Vision Science & Technology October 2022, Vol.11, 37. doi:https://doi.org/10.1167/tvst.11.10.37

Clinical Trials

Efficacy Comparison of Repeated Low-Level Red Light and Low-Dose Atropine for Myopia Control: A Randomized Controlled Trial Open Access

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Yanxian Chen; Ruilin Xiong; Xu Chen; Jian Zhang; Gabriella Bulloch; Xiaoxuan Lin; Xiaoman Wu; Jinying Li

Tags: atropine, myopia, randomized controlled trial

Translational Vision Science & Technology October 2022, Vol.11, 33. doi:https://doi.org/10.1167/tvst.11.10.33

Virtual Reality Hemifield Measurements for Corrective Surgery Eligibility in Ptosis Patients: A Pilot Clinical Trial Open Access

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Margarita Labkovich; Andrew J. Warburton; Stephanie Ying; Aly A. Valliani; Nicholas Kissel; Randal A. Serafini; Raj Mathew; Megan Paul; S. Malin Hovstadius; Vicente N. Navarro; Aashay Patel; Harsha Reddy; James G. Chelnis

Tags: surgical procedures, operative, visual fields, virtual reality, eye, perimetry

Translational Vision Science & Technology October 2022, Vol.11, 35. doi:https://doi.org/10.1167/tvst.11.10.35

Letters to the Editor

Letter to the Editor: Expected Improvement in Structure–Function Agreement With Macular Displacement Models Open Access

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Giovanni Montesano; David F. Garway-Heath; David P. Crabb

Tags: eye, face, glaucoma, maps, optic disk

Translational Vision Science & Technology October 2022, Vol.11, 14. doi:https://doi.org/10.1167/tvst.11.10.14

Author Response: Expected Improvement in Structure-Function Agreement With Macular Displacement Models Open Access

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Janelle Tong; Jack Phu; David Alonso-Caneiro; Sieu K. Khuu; Michael Kalloniatis

Tags: exercise, retinal ganglion cells, visual fields, myopia, glaucoma

Translational Vision Science & Technology October 2022, Vol.11, 15. doi:https://doi.org/10.1167/tvst.11.10.15

Erratum

Erratum in: A New Method for Visualizing Drusen and Their Progression in Flood-Illumination Adaptive Optics Ophthalmoscopy Open Access

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Translational Vision Science & Technology October 2022, Vol.11, 29. doi:https://doi.org/10.1167/tvst.11.10.29

Erratum in: Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury Open Access

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Translational Vision Science & Technology October 2022, Vol.11, 30. doi:https://doi.org/10.1167/tvst.11.10.30

Erratum in: SZN-413, a FZD4 Agonist, as a Potential Novel Therapeutic for the Treatment of Diabetic Retinopathy Open Access

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Translational Vision Science & Technology October 2022, Vol.11, 31. doi:https://doi.org/10.1167/tvst.11.10.31

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