Volume 14 Issue 4 | TVST

Cornea & External Disease

Characterization of Directional Reflectance in Corneal Tissue: A Comprehensive Optical Coherence Tomography Analysis Open Access

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Jad F. Assaf; Jiachi Hong; Yan Li; David Huang

Tags: cornea, incidence, optical coherence tomography, body tissue

Translational Vision Science & Technology April 2025, Vol.14, 7. doi:https://doi.org/10.1167/tvst.14.4.7

Metabolic Biomarkers Mediate Allergic Conjunctivitis via Circulating Inflammatory Proteins: Evidence From a Mendelian Randomization Study Open Access

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Xiang Cao; Zijiao Xu; Boyang Zhang; Qingyu Li; Zhixin Jiang; Xiaoyong Yuan

Tags: allergic conjunctivitis, biological markers, mendelian randomization analysis, modified barium swallow, proteins

Translational Vision Science & Technology April 2025, Vol.14, 12. doi:https://doi.org/10.1167/tvst.14.4.12

Hyperbaric Oxygenation Increases Available Oxygen and Resistance to Enzymatic Digestion in Accelerated Corneal Collagen Crosslinking Open Access

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Johannes Menzel-Severing; Theresa Streit; Jule Schmiedel; Sven Dreyer; Theo G. Seiler; Joana Witt; Gerd Geerling

Tags: corneal collagen cross-linking, digestion, hyperbaric oxygenation, oxygen, cornea

Translational Vision Science & Technology April 2025, Vol.14, 13. doi:https://doi.org/10.1167/tvst.14.4.13

Causal Relationship Between Common Allergic Diseases and Keratoconus: A Two-Sample Mendelian Randomization Study Open Access

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Xiru Yang; Xinyao Yu; Shan Gao; Pinghui Wei; Guoge Han

Tags: extrinsic asthma, hypersensitivity, keratoconus, mendelian randomization analysis, atopic dermatitis

Translational Vision Science & Technology April 2025, Vol.14, 14. doi:https://doi.org/10.1167/tvst.14.4.14

An Improved Monte Carlo Method for Quantitative Analysis of Transparency Degradation Caused by Corneal Edema Open Access

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Shuaiyi Li; Yiping Liu; Bao Yang; Sulei Lv; Xiulan Zou; Liqun Tang; Licheng Zhou; Zhenyu Jiang; Zejia Liu

Tags: catabolism, cornea, corneal edema, monte carlo method, transparency

Translational Vision Science & Technology April 2025, Vol.14, 15. doi:https://doi.org/10.1167/tvst.14.4.15

A Novel Approach to Fabricate Early Keratoconus Phantom Models Open Access

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Hui Tong; Mingjue Wu; Jianqiang Han; Lin Li; Haixia Zhang

Tags: cornea, keratoconus, phantoms, imaging, silicones

Translational Vision Science & Technology April 2025, Vol.14, 18. doi:https://doi.org/10.1167/tvst.14.4.18

A Tear-Based Approach for Rapid Identification of Bacterial Pathogens in Corneal Ulcers Using Nanopore Sequencing Open Access

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Mark Dibbs; Mitchelle Matesva; Despoina Theotoka; Christina Jayaraj; Beruk Metiku; Patrick Demkowicz; Jacob S. Heng; Yvonne Wang; Christine Y. Bakhoum; Jessica Chow; Mathieu F. Bakhoum

Tags: bacteria, corneal ulcer, nanopore sequencing, pathogenic organism, ulcer

Translational Vision Science & Technology April 2025, Vol.14, 19. doi:https://doi.org/10.1167/tvst.14.4.19

Glaucoma

Longitudinal Change in Retinal Nerve Fiber Layer Thickness and Intraocular Pressure in Young Adults Open Access

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Samantha Sze-Yee Lee; Gareth Lingham; Alex W. Hewitt; David A. Mackey

Tags: intraocular pressure, retinal nerve fiber layer, young adult, eye, ophthalmic examination and evaluation

Translational Vision Science & Technology April 2025, Vol.14, 3. doi:https://doi.org/10.1167/tvst.14.4.3

Comparison of the Humphrey Field Analyzer and MP-3 Microperimeter in Patients With Glaucoma, Classified by Severity and Misalignment of Test Points Open Access

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Taiga Inooka; Ryo Tomita; Taro Kominami; Marie Mochizuki; Koji M. Nishiguchi; Kenya Yuki

Tags: glaucoma, open-angle glaucoma, eye, reliability

Translational Vision Science & Technology April 2025, Vol.14, 6. doi:https://doi.org/10.1167/tvst.14.4.6

Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition Open Access

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Nana Takahashi; Yukihiro Shiga; Naoki Kiyota; Masayuki Yasuda; Naoki Takahashi; Kota Sato; Ryutaro Arita; Akiko Kikuchi; Shin Takayama; Tadashi Ishii; Toru Nakazawa

Tags: common cold, open-angle glaucoma, optic disk, vascular flow, cold sensation

Translational Vision Science & Technology April 2025, Vol.14, 9. doi:https://doi.org/10.1167/tvst.14.4.9

Association Between Cup-to-Disc Ratio and Structural and Functional Damage Parameters in Glaucoma: Insights From Multiparametric Modeling Open Access

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Aliah McCalla; Mengyu Wang; Mohammad Eslami; Saber Kazeminasab; Yan Luo; Hannah Rana; Sajib Saha; Min Shi; Yu Tian; Nazlee Zebardast; Tobias Elze

Tags: glaucoma, clinicians, optic disk

Translational Vision Science & Technology April 2025, Vol.14, 17. doi:https://doi.org/10.1167/tvst.14.4.17

Longitudinal Simulated Driving Performance and Rates of Progressive Visual Field Loss in Glaucoma Open Access

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Davina A. Malek; Alberto Diniz-Filho; Erwin R. Boer; Felipe A. Medeiros

Tags: blindness, glaucoma, reaction time, divided attention, visual fields

Translational Vision Science & Technology April 2025, Vol.14, 21. doi:https://doi.org/10.1167/tvst.14.4.21

New Threshold for Large Optic Discs in Children Using Bruch's Membrane Opening Area Open Access

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Julia V. Stingl; Cordula Braun; Sara Walter; Jasmin Rezapour; Felix M. Wagner; Lucy Shen; Alicja Strzalkowska; Irene Schmidtmann; Alexander K. Schuster; Esther M. Hoffmann

Tags: bruch's basal membrane, child, optics, glaucoma, optic disk

Translational Vision Science & Technology April 2025, Vol.14, 24. doi:https://doi.org/10.1167/tvst.14.4.24

Lens

Association of Per- and Polyfluoroalkyl Substance Exposure With Cataract Prevalence Among U.S. Adults: A NHANES Analysis (2005–2008) Open Access

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Yuti Liu; Jiazhen Yao; Mingxue Ren; Lingxia Ye; An-Peng Pan; Xu Xu

Tags: cataract, fluorocarbons, prevalence, national health and nutrition examination survey, adult

Translational Vision Science & Technology April 2025, Vol.14, 1. doi:https://doi.org/10.1167/tvst.14.4.1

Refractive Intervention

Assessment of Corneal Biomechanical Changes After Discontinuation of Long-Term Orthokeratology: A 2-Year Prospective Study Open Access

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Hou-Ren Tsai; Jeng-Hung Wang; Cheng-Jen Chiu

Tags: cornea, orthokeratology, prospective studies, lens (device), lens, crystalline

Translational Vision Science & Technology April 2025, Vol.14, 5. doi:https://doi.org/10.1167/tvst.14.4.5

Retina

Structural Updates to the Implant and Refill Needle of the Port Delivery Platform Open Access

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Dante J. Pieramici; Peter A. Campochiaro; Margaret Chang; Ian Pearce; Carl D. Regillo; Shamika Gune; Nancy Holekamp; Carlos Quezada-Ruiz; Shrirang V. Ranade; Natasha Singh; Geoffrey Wise; Joshua Horvath

Tags: implants, needles

Translational Vision Science & Technology April 2025, Vol.14, 8. doi:https://doi.org/10.1167/tvst.14.4.8

Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment Open Access

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Kao-Jung Chang; Ching-Yun Wang; Hsin-Yu Wu; Pei-Yu Weng; Chia-Hsin Lu; Wei Chiu; Wei-Chieh Fang; Chong-En Kao; Cheng-Yi Li; Yi-Ting Chung; Yu-Chun Chen; Ai-Ru Hsieh; Shih-Hwa Chiou; Chih-Chien Hsu; Tai-Chi Lin; Shih-Jen Chen; De-Kuang Hwang

Tags: biological markers, polygenic risk score, retinal detachment, screening, ultrasonography

Translational Vision Science & Technology April 2025, Vol.14, 16. doi:https://doi.org/10.1167/tvst.14.4.16

Characterizing the Field of Fluidic Effect Around Vitrectomy Probes Using Particle Image Velocimetry Open Access

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Dhamotharan Veerasamy; Daria Vedeniapina; Michael Wilkes; David H. Steel; Richard D. Whalley

Tags: fluid flow, particle image velocimetry, pulmonary aspiration, velocity, vitrectomy

Translational Vision Science & Technology April 2025, Vol.14, 20. doi:https://doi.org/10.1167/tvst.14.4.20

Radiomics-Based OCT Analysis of Choroid Reveals Biomarkers of Central Serous Chorioretinopathy Open Access

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Ryan Chace Williamson; Kiran Kumar Vupparaboina; Sandeep Chandra Bollepalli; Mohammed Nasar Ibrahim; Nicola Valsecchi; Arman Zarnegar; José-Alain Sahel; Jay Chhablani

Tags: biological markers, central serous chorioretinopathy, choroid, eye, radiomics

Translational Vision Science & Technology April 2025, Vol.14, 23. doi:https://doi.org/10.1167/tvst.14.4.23

Uveitis

Identification of Subtypes of Herpetic Anterior Uveitis and Characterization of Their Clinical Features and Visual Outcome in a Chinese Population Open Access

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Hui Liu; Suo Guo; Yaning Liu; Guannan Su; Peizeng Yang

Tags: chinese (other dialects), signs and symptoms, uveitis, anterior, chinese people, cytomegalovirus

Translational Vision Science & Technology April 2025, Vol.14, 2. doi:https://doi.org/10.1167/tvst.14.4.2

Clinical Trials

Effect of Repeated Low-Level Red Light Versus 0.01% Topical Atropine on Myopia Progression: A Randomized Crossover-Controlled Trial Open Access

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Xuena Pang; Xuemin Jin; Aicun Fu; Weiqun Wang; Bingxin Zhao; Lili Shang; Minghang Chang; Nana Ma; Guangying Zheng

Tags: atropine, myopia, child, red light

Translational Vision Science & Technology April 2025, Vol.14, 22. doi:https://doi.org/10.1167/tvst.14.4.22

Review

An Emerging Global Threat of Mycotic Keratitis Caused by Uncommon Fungal Species: A Systematic Review and Meta-Analysis Open Access

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Megha Gautam; Babu Lal; Smita Patel; Rajiv R. Mohan; Arivarasan Barathi; Nikita Yadav; Sunil Kumar Verma; Richa Nyodu; Ananyan Sampath; Darshna Koshti; Bhavana Sharma

Tags: fungal keratitis, meta-analysis, prevalence, systematic reviews, atypical

Translational Vision Science & Technology April 2025, Vol.14, 4. doi:https://doi.org/10.1167/tvst.14.4.4

Letters to the Editor

The Future of Retinitis Pigmentosa Research: Unlocking the Potential of Branched-Chain Amino Acid Therapy Open Access

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Qinling Jiang; Lin Mou

Tags: amino acids, branched-chain, retinitis pigmentosa

Translational Vision Science & Technology April 2025, Vol.14, 10. doi:https://doi.org/10.1167/tvst.14.4.10

Comments on Xie et al.’s Study on Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy Open Access

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James Lin; Ting-Wan Kao

Tags: artificial intelligence, biological markers, diabetic nephropathy, perfusion, screening

Translational Vision Science & Technology April 2025, Vol.14, 11. doi:https://doi.org/10.1167/tvst.14.4.11

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