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Editorial

A Catalog of Patent Applications Published in 2024 Related to Ophthalmology and Vision Science Open Access
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Guillaume Stern; Benjamin Stern; Jonathan J. Mallett; Roy S. Chuck
Tags: ophthalmology, patents, vision
Translational Vision Science & Technology May 2025, Vol.14, 16. doi:https://doi.org/10.1167/tvst.14.5.16

Artificial Intelligence

PhacoTrainer: Automatic Artificial Intelligence-Generated Performance Ratings for Cataract Surgery Open Access
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Hsu-Hang Yeh; Simmi Sen; Jonathan C. Chou; Karen L. Christopher; Sophia Y. Wang
Tags: cataract, cataract surgery, intelligence, surgeons, surgical procedures, operative
Translational Vision Science & Technology May 2025, Vol.14, 2. doi:https://doi.org/10.1167/tvst.14.5.2
High-Accuracy Digitization of Humphrey Visual Field Reports Using Convolutional Neural Networks Open Access
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Shian-Sen Shie; Wei-Wen Su
Tags: convolutional neural networks, humphrey visual field plot, metadata, training, visual fields
Translational Vision Science & Technology May 2025, Vol.14, 6. doi:https://doi.org/10.1167/tvst.14.5.6
Grading of Foveal Hypoplasia Using Deep Learning on Retinal Fundus Images Open Access
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Tsung-Ying Tsai; Ying-Feng Chang; Eugene Yu-Chuan Kang; Kuan-Jen Chen; Nan-Kai Wang; Laura Liu; Yih-Shiou Hwang; Chi-Chun Lai; Sin-You Chen; Jenhui Chen; Chao-Sung Lai; Wei-Chi Wu
Tags: deep learning, foveal hypoplasia, datasets, clinicians
Translational Vision Science & Technology May 2025, Vol.14, 18. doi:https://doi.org/10.1167/tvst.14.5.18
Using Artificial Intelligence for an Efficient Prediction of Outcomes of Deep Anterior Lamellar Keratoplasty (DALK) in Advanced Keratoconus Open Access
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Gairik Kundu; Sharon D'Souza; Durgalaxmi Modak; Srihari Balaraj; Rohit Shetty; Rudy M. M. A. Nuijts; Raghav Narasimhan; Abhijit Sinha Roy
Tags: artificial intelligence, eye, keratoconus, keratoplasty, tomography
Translational Vision Science & Technology May 2025, Vol.14, 30. doi:https://doi.org/10.1167/tvst.14.5.30

Cornea & External Disease

Unraveling the Link Between Obesity and Keratoconus Risk Based on Genetic Evidence Open Access
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Yuke Huang; Jiejie Zhuang; Chang Liu; Shiji Liu; Huanhuan Ren; Qitong Zhang; Yan Li; Jin Qiu; Na Yu; Keming Yu; Xi Chen; Jing Zhuang
Tags: genetics, keratoconus, obesity
Translational Vision Science & Technology May 2025, Vol.14, 20. doi:https://doi.org/10.1167/tvst.14.5.20
The Efficacy and Safety of Oxygen-Enriched Rose Bengal and Green Light Corneal Crosslinking Open Access
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Rongrong Gao; Ming Chen; Wenqian Xing; Qingqing Jiang; Keith M. Meek; Qinmei Wang; A-Yong Yu; Jinhai Huang
Tags: cornea, corneal collagen cross-linking, eye, green light, mass or substance concentration per volume
Translational Vision Science & Technology May 2025, Vol.14, 22. doi:https://doi.org/10.1167/tvst.14.5.22

Glaucoma

Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use—A Prospective Study Open Access
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Yu-Ting Tsao; Hung-Chi Chen; Yi-Jen Hsueh; Yu-Chun Cheng; Eugene Yu-Chuan Kang; Chu-Yen Huang; Yung-Sung Lee
Tags: antioxidants, aqueous humor, glaucoma, intraocular pressure, teller acuity cards
Translational Vision Science & Technology May 2025, Vol.14, 7. doi:https://doi.org/10.1167/tvst.14.5.7
Normative Variability in Retinal Nerve Fiber Layer Thickness: Does It Matter Where the Peaks Are? Open Access
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Sowjanya Gowrisankaran; Ashkan Abbasi; Xubo Song; Joel S. Schuman; Gadi Wollstein; Bhavna J. Antony; Hiroshi Ishikawa
Tags: glaucoma, optic disk, retinal nerve fiber layer, retinal vessels
Translational Vision Science & Technology May 2025, Vol.14, 13. doi:https://doi.org/10.1167/tvst.14.5.13
Usefulness of Measuring Corneal Stiffness in Predicting the Reduction of Intraocular Pressure With Microhook Ab Interno Trabeculotomy Open Access
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Kei Asaoka; Yuri Fujino; Honami Fukuyo; Hiroshi Murata; Shuichiro Aoki; Kaori Ishii; Yoshiaki Kiuchi; Ryo Asaoka
Tags: cornea, intraocular pressure, trabeculotomy, postoperative care, glaucoma
Translational Vision Science & Technology May 2025, Vol.14, 19. doi:https://doi.org/10.1167/tvst.14.5.19
Presbyopia Progression From the Age of 40 to 79 Years in Glaucoma Patients Treated With Prostaglandin F Receptor Agonists Open Access
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Masahiko Ayaki; Akiko Hanyuda; Kazuno Negishi
Tags: agonists, glaucoma, presbyopia, prostaglandins f
Translational Vision Science & Technology May 2025, Vol.14, 25. doi:https://doi.org/10.1167/tvst.14.5.25

Low Vision Rehabilitation

Using ChatGPT To Generate Walking Directions—Could It Potentially Help Visually Impaired With Micronavigation? Open Access
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Junxian He; Shrinivas Pundlik; Gang Luo
Tags: chatgpt, datasets, gait, walking (activity)
Translational Vision Science & Technology May 2025, Vol.14, 28. doi:https://doi.org/10.1167/tvst.14.5.28

Pediatric Ophthalmology & Strabismus

Association Between Optic Nerve Morphology by Handheld Spectral Domain Optical Coherence Tomography and Intracranial Pathology in Preterm Infants Open Access
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Hyeshin Jeon; Jason Bunk; Claire Park; Krystle M. Perez; Manjiri Dighe; Leona Ding; Laura E. Grant; Ayesha Shariff; Thomas B. Gillette; Kristina Tarczy-Hornoch; Michelle T. Cabrera
Tags: brain pathology, infant, premature, language morphology, mobile devices, morphology
Translational Vision Science & Technology May 2025, Vol.14, 17. doi:https://doi.org/10.1167/tvst.14.5.17

Refractive Intervention

Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study Open Access
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Yue Xu; Xing-Xuan Dong; Yun Wang; Xin-Yu Zhuang; Ying-Jie Chen; Xiao-Feng Zhang; Chen-Wei Pan
Tags: cytokine, mendelian randomization analysis, refractive errors, ciliary motility disorders
Translational Vision Science & Technology May 2025, Vol.14, 1. doi:https://doi.org/10.1167/tvst.14.5.1
Distance of Corneal Vertex and Effective Optical Zone Margin Following Keratorefractive Lenticule Extraction in Myopic Astigmatism Open Access
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Xuyun Meng; Hui Ding; Hong He; Zhenduo Yang; Xiaodan Chen; Shisi Hu; Anzhen Li; Xingxing Wang; Yuhan Luo; Xingwu Zhong
Tags: astigmatism, cornea, crown of head, optics, postoperative care
Translational Vision Science & Technology May 2025, Vol.14, 21. doi:https://doi.org/10.1167/tvst.14.5.21
Significant Loss of Coordination Among Astigmatism Components in Young Chinese Adults With High Myopia Open Access
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Wenzai An; Shifei Wei; Shi-Ming Li; Kai Cao; Jianping Hu; Caixia Lin; Weiling Bai; Jing Fu; Yunyun Sun; Ningli Wang
Tags: astigmatism, myopia, refractive errors, adult, chinese (other dialects)
Translational Vision Science & Technology May 2025, Vol.14, 26. doi:https://doi.org/10.1167/tvst.14.5.26

Retina

Age-Related Regional Changes in Choroidal Vascularity in Healthy Emmetropic Eyes Open Access
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Ghazal Valizadeh; Hosein Hoseini-Yazdi; Scott Read; David Alonso-Caneiro; Michael Collins
Tags: adult, cardiovascular imaging, child, cortical blindness, diagnostic imaging
Translational Vision Science & Technology May 2025, Vol.14, 3. doi:https://doi.org/10.1167/tvst.14.5.3
Genetic Evidence Supporting a Causal Association Between mTORC1-Dependent Circulating Protein Levels and Diabetic Retinopathy Open Access
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Yaqi Bai; Yujia Xi; Chenwei Gui; Guohai Huang; Guohong Zhou
Tags: diabetic retinopathy, genetics, mechanistic target of rapamycin complex 1, proteins
Translational Vision Science & Technology May 2025, Vol.14, 4. doi:https://doi.org/10.1167/tvst.14.5.4
Long-Term Natural History of Treatment-Naïve Geographic Atrophy in Age-Related Macular Degeneration Open Access
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Daniel R. Muth; Laurence Quérat; Abinaya P. Venkataraman; Alberto Dominguez-Vicent; Goran Petrovski; Pete A. Williams; Filippo Locri; Sandrine A. Zweifel; Anders Kvanta
Tags: age-related macular degeneration, age-related macular degeneration, nonexudative, follow-up, natural history, eye
Translational Vision Science & Technology May 2025, Vol.14, 5. doi:https://doi.org/10.1167/tvst.14.5.5
Exploring Therapeutic Targets for Age-Related Macular Degeneration From Circulating Proteins to Plasma Metabolites in the European Population Open Access
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Chengming Chen; Yanyan Lan; Weiming Yan; Xiaohong Zhang; Tian Li; Jing Han
Tags: age-related macular degeneration, metabolites, plasma, proteins, european continental ancestry group
Translational Vision Science & Technology May 2025, Vol.14, 8. doi:https://doi.org/10.1167/tvst.14.5.8
Comparing the Efficiency of Fluid Infusion Systems for Pars Plana Vitrectomy Open Access
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Tommaso Rossi; Giorgio Querzoli; Giov Battista Angelini; Veronica Santoro; Camilla Pellizzaro; David H. Steel; Mariacristina Parravano; Mario R. Romano
Tags: infusion procedures, infusion sets, vitrectomy, trocar, pars plana
Translational Vision Science & Technology May 2025, Vol.14, 10. doi:https://doi.org/10.1167/tvst.14.5.10
Face and Available Chair Detection and Localization With a Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis Open Access
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Lisa Lombardi; Matthew A. Petoe; Lauren Moussallem; Maria Kolic; Elizabeth K. Baglin; Samuel Stefopoulos; Xerxes Battiwalla; Janine G. Walker; Nick Barnes; Carla J. Abbott; Penelope J. Allen; for the Bionics Institute and Centre for Eye Research Australia Retinal Prosthesis Consortium
Tags: brca2 gene, congenital heart disease, coronary arteriosclerosis, coronary heart disease, face
Translational Vision Science & Technology May 2025, Vol.14, 11. doi:https://doi.org/10.1167/tvst.14.5.11
A Simple and Rapid Method for Simultaneous Isolation of Mouse Retina and RPE Wholemounts Open Access
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Jialiang Yang; Haiping Wu; Qi Li; Jiaxin Guo; Jialin Yao; Shengliu Pan; Xiawei Wu; Haotian Huang; Runfang Chen; Junnian Chen; Yubin Wang; Yue Peng; Fuhua Wu; Jing Hu
Tags: mice, patient isolation, retina, social isolation, phosphate-buffered saline
Translational Vision Science & Technology May 2025, Vol.14, 14. doi:https://doi.org/10.1167/tvst.14.5.14
Area Under the Curve Analysis in a Real-World Cohort of Finnish Patients Treated for Neovascular Age-Related Macular Degeneration Open Access
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Terhi Ollila; Ashwini Joshi; Sangita Kulathinal; Ilkka Immonen
Tags: area under curve, cohort studies, exudative age-related macular degeneration, finnish, visual acuity
Translational Vision Science & Technology May 2025, Vol.14, 23. doi:https://doi.org/10.1167/tvst.14.5.23
Discrepancies Between Autofluorescence Imaging Modalities in CNGB3-Associated Achromatopsia and Correlation With Ellipsoid Zone Continuity Open Access
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Haseeb N. Akhtar; Chun Fung Jeffrey Lam; Siying Lin; Gavin Arno; Jose S. Pulido; Andrew R. Webster; Michel Michaelides; Omar A. Mahroo
Tags: achromatopsia, autofluorescence, diagnostic imaging, eye
Translational Vision Science & Technology May 2025, Vol.14, 24. doi:https://doi.org/10.1167/tvst.14.5.24
Perifoveal Choriocapillaris Flow Deficits Associated With Cerebrospinal Fluid Aβ42/tau in Presymptomatic Alzheimer's Disease Open Access
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Jane W. Chan; Giulia Corradetti; Xiaomeng Wu; Natalie Astraea; Xianghong Arakaki; Alfred N. Fonteh; Astrid M. Suchy-Dicey; SriniVas Sadda
Tags: alzheimer's disease, biological markers, cerebrospinal fluid, fluid flow, tau proteins
Translational Vision Science & Technology May 2025, Vol.14, 27. doi:https://doi.org/10.1167/tvst.14.5.27

Uveitis

Associations Between the Gut Microbiota and Its Related Metabolic Pathways and Uveitis: A Bidirectional Two-Sample Mendelian Randomization Study Open Access
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Maomei Luo; Zhen Xing; Yanhao Gou; Xianlin Yang; Xinran Zhang; Wei Yu; Hongbin Lv
Tags: gastrointestinal microbiome, uveitis, mendelian randomization analysis
Translational Vision Science & Technology May 2025, Vol.14, 15. doi:https://doi.org/10.1167/tvst.14.5.15
Novel Artificial Intelligence–Based Quantification of Anterior Chamber Inflammation Using Vision Transformers Open Access
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Carlos Cifuentes-González; Laura Gutiérrez-Sinisterra; William Rojas-Carabali; Joewee Boon; Atharva Hudlikar; Xin Wei; Leonid Shchurov; Hnin Hnin Oo; Nicholas Chieh Loh; Choo Sheriel Shannon; Laura Daniela Rodríguez-Camelo; Bernett Lee; Alejandra de-la-Torre; Rupesh Agrawal
Tags: cardiac ct, inflammation, uveitis, vision, anterior chamber of eye
Translational Vision Science & Technology May 2025, Vol.14, 31. doi:https://doi.org/10.1167/tvst.14.5.31

Clinical Trials

Polydioxanone Membrane for Guided Conjunctival Tissue Reconstruction: An Experimental Model in Rabbits Open Access
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Daniel Diniz da Gama; Gabriela Martines; Moacyr Rigueiro; Matheus Cruz; Paulo Schor
Tags: body tissue, conjunctiva, oryctolagus cuniculus, polydioxanone, reconstructive surgical procedures
Translational Vision Science & Technology May 2025, Vol.14, 29. doi:https://doi.org/10.1167/tvst.14.5.29

Methods

Distance From the Foveal Center: A Method for the Calculation of Eccentric Fixation Open Access
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Thales A. C. de Guimaraes; Angelos Kalitzeos; James Bainbridge; Michel Michaelides
Tags: eccentric fixation, eye
Translational Vision Science & Technology May 2025, Vol.14, 9. doi:https://doi.org/10.1167/tvst.14.5.9

Research Opportunities

Advancing Toward a World Without Vision Loss From Diabetes: Insights From The Mary Tyler Moore Vision Initiative Symposium 2024 on Curing Vision Loss From Diabetes Open Access
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Ward Fickweiler; Konstantina Sampani; Dorene S. Markel; S. Robert Levine; Jennifer K. Sun; Thomas W. Gardner
Tags: blindness, diabetes mellitus, myopic foveoschisis, vision, medication therapy management
Translational Vision Science & Technology May 2025, Vol.14, 12. doi:https://doi.org/10.1167/tvst.14.5.12
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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