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Retina October 2024

Multi-Characteristic Opsin Therapy to Functionalize Retina, Attenuate Retinal Degeneration, and Restore Vision in Mouse Models of Retinitis Pigmentosa

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Subrata Batabyal; Sanghoon Kim; Michael Carlson; Darryl Narcisse; Kissaou Tchedre; Adnan Dibas; Najam A. Sharif; Samarendra Mohanty
TAGS: intravitreal injections, mice, retina, retinal degeneration, vision, injections, tissue degeneration
Trans. Vis. Sci. Tech.. 2024; 13(10):25. https://doi.org/10.1167/tvst.13.10.25

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Laser Delivery of PEDF Gene into Retina Led to Neuroprotection and Anti-angiogenesis in mice

Sanghoon kim; Subrata Batabyal; Michael Carlson; Adnan Dibas; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1249.

ARVO Annual Meeting Abstract June 2024

Multi-characteristic opsin gene therapy attenuates retinal degeneration and restore vision in mouse models of retinitis pigmentosa

Subrata Batabyal; Sanghoon Kim; Michael Carlson; Darryl Narcisse; Kissaou Tchedre; Adnan Dibas; Najam (Naj) Sharif; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5356.

ARVO Annual Meeting Abstract June 2024

Trabecular Meshwork Targeting Engineered Microbial Mechanosensitive Channel for Enhancing Outflow Facility in TGFb Animal Model of Glaucoma

Adnan Dibas; Lucero Garcia; Megan Aldape; Sanghoon Kim; Subrata Batabyal; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5129.

ARVO Annual Meeting Abstract June 2024

In vivo efficacy of a novel multi-characteristic opsin (MCO-010) in a mouse model of Leber congenital amaurosis

Najam (Naj) Sharif; Subrata Batabyal; Adnan Dibas; Michael Carlson; Sanghoon Kim; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6096.

ARVO Annual Meeting Abstract June 2023

Sonogenetic Vision Restoration for Inherited Retinal Disorders

Subrata Batabyal; Gengxi Lu; Adnan Dibas; Michael Carlson; Sanghoon Kim; Houssam Al Saad; Darryl Narcisse; Mark S. Humayun; Qifa Zhou; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):783.

ARVO Annual Meeting Abstract June 2023

Non-viral Targeted Laser Delivery of Multi-Characteristic Opsin Genes for Treatment of Geographic Atrophy

Samarendra Mohanty; Sanghoon Kim; Subrata Batabyal; Michael Carlson; Houssam Al Saad; Benjamin Ferguson; Adnan Dibas

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3861.

ARVO Annual Meeting Abstract June 2023

Engineered Mechanosensitive Channel as Outflow Actuator for Gene Agnostic Gene Therapy of Glaucoma

Adnan Dibas; Subrata Batabyal; Houssam Al Saad; Darryl Narcisse; Sanghoon Kim; Michael Carlson; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3790.

ARVO Annual Meeting Abstract June 2023

Novel small molecules with anti-inflammatory and anti-angiogenic activity in mouse model of retinopathy.

Adam Dayoub; Suchismita Acharya; Sumita Behera; Adnan Dibas

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3501.

ARVO Annual Meeting Abstract June 2022

AAV-carried MCO Optogenetic Therapy for the Treatment of Inherited Retinal Disorders

Subrata Batabyal; Adnan Dibas; Houssam Al-Saad; Sanghoon Kim; Michael Carlson; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):74 – A0047.

ARVO Annual Meeting Abstract June 2021

The anti-inflammatory and neuroprotective activity of novel hybrid molecule SA-10 in in vitro ischemic models

Suchismita Acharya; Lorea Gamboa Acha; Sudershan Gondi; Adnan Dibas; Charles Amankwa; Steven Roth; Biji Mathew

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):538.

ARVO Annual Meeting Abstract June 2020

Novel small hybrid molecule with cytoprotective and IOP lowering activity

Suchismita Acharya; Courtney Weston; Dorette Z Ellis; Adnan Dibas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2721.

ARVO Annual Meeting Abstract June 2020

Safe non-viral light-based spatially targeted delivery of therapeutic opsin-encoding genes into specific cell types

Subrata Batabyal; Sanghoon Kim; Michael Carlson; Darryl Narcisse; Kissaou Tchedre; Adnan Dibas; Melissa Galicia; Weldon Wright; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4502.

ARVO Annual Meeting Abstract June 2020

Monitoring Visual Cortical Activity using Functional Bioluminescence imaging

Darryl Narcisse; Sourajit Mustafi; Melissa Galicia; Michael Calrson; adnan Dibas; Subrata Batabyal; Sanghoon Kim; Benjamin Puig; Weldon Wright; Samarendra Mohanty

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):899.

ARVO Annual Meeting Abstract July 2019

The hybrid compound SA-2 is neuroprotective in a rodent model of eye stroke

Adnan Dibas; Wei Zhang; Sai Chavala; Suchismita Acharya

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5383.

ARVO Annual Meeting Abstract July 2019

Novel small molecule with neuroprotective activity

Suchismita Acharya; Adnan Dibas; Zhang Wei; Sai H Chavala

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):29.

Retina July 2019

Hybrid Compound SA-2 is Neuroprotective in Animal Models of Retinal Ganglion Cell Death

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Dorota L. Stankowska; Adnan Dibas; Linya Li; Wei Zhang; Vignesh R. Krishnamoorthy; Sai H. Chavala; Tam Phung Nguyen; Thomas Yorio; Dorette Z. Ellis; Suchismita Acharya
TAGS: animal model, electroretinography, eye, mice, neuroprotection, retina, retinal ganglion cells, wounds and injuries, hypoxia, ischemia
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3064-3073. https://doi.org/10.1167/iovs.18-25999

ARVO Annual Meeting Abstract June 2017

Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASIC) in optic nerve crush model in rodents

Adnan Dibas; Dorota Stankowska; Brett Mueller; Oku Hidehiro; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3405.

ARVO Annual Meeting Abstract September 2016

Increased expression of glucocorticoid receptor B induces a novel transforming growth factor beta-2 isoform in trabecular meshwork cells

Adnan Dibas; Abbot F Clark; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):86.

ARVO Annual Meeting Abstract June 2015

Role of Importins and Exportins in steroid-induced effects in trabecular meshwork

Adnan Dibas; Abbot F Clark; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4855.

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Multi-Characteristic Opsin Therapy to Functionalize Retina, Attenuate Retinal Degeneration, and Restore Vision in Mouse Models of Retinitis Pigmentosa

Laser Delivery of PEDF Gene into Retina Led to Neuroprotection and Anti-angiogenesis in mice

Multi-characteristic opsin gene therapy attenuates retinal degeneration and restore vision in mouse models of retinitis pigmentosa

Trabecular Meshwork Targeting Engineered Microbial Mechanosensitive Channel for Enhancing Outflow Facility in TGFb Animal Model of Glaucoma

In vivo efficacy of a novel multi-characteristic opsin (MCO-010) in a mouse model of Leber congenital amaurosis

Sonogenetic Vision Restoration for Inherited Retinal Disorders

Non-viral Targeted Laser Delivery of Multi-Characteristic Opsin Genes for Treatment of Geographic Atrophy

Engineered Mechanosensitive Channel as Outflow Actuator for Gene Agnostic Gene Therapy of Glaucoma

Novel small molecules with anti-inflammatory and anti-angiogenic activity in mouse model of retinopathy.

AAV-carried MCO Optogenetic Therapy for the Treatment of Inherited Retinal Disorders

The anti-inflammatory and neuroprotective activity of novel hybrid molecule SA-10 in in vitro ischemic models

Novel small hybrid molecule with cytoprotective and IOP lowering activity

Safe non-viral light-based spatially targeted delivery of therapeutic opsin-encoding genes into specific cell types

Monitoring Visual Cortical Activity using Functional Bioluminescence imaging

The hybrid compound SA-2 is neuroprotective in a rodent model of eye stroke

Novel small molecule with neuroprotective activity

Hybrid Compound SA-2 is Neuroprotective in Animal Models of Retinal Ganglion Cell Death

Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASIC) in optic nerve crush model in rodents

Increased expression of glucocorticoid receptor B induces a novel transforming growth factor beta-2 isoform in trabecular meshwork cells

Role of Importins and Exportins in steroid-induced effects in trabecular meshwork

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