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Glaucoma April 2025

Longitudinal Change in Retinal Nerve Fiber Layer Thickness and Intraocular Pressure in Young Adults

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Samantha Sze-Yee Lee; Gareth Lingham; Alex W. Hewitt; David A. Mackey
TAGS: intraocular pressure, retinal nerve fiber layer, young adult, eye, ophthalmic examination and evaluation
Trans. Vis. Sci. Tech.. 2025; 14(4):3. https://doi.org/10.1167/tvst.14.4.3

Includes: Supplemental Content

Retina March 2025

Genome-Wide Association Study to Identify Genetic Variants Associated With Diabetic Maculopathy

PDF

Rajya L. Gurung; Charvi Nangia; Tengda Cai; Liesel M. FitzGerald; Bennet J. McComish; Ebony Liu; Georgia Kaidonis; Bronwyn Ridge; Alex W. Hewitt; Brendan Vote; Nitin Verma; Jamie E. Craig; Colin N. A. Palmer; Kathryn P. Burdon; Weihua Meng
TAGS: cohort studies, diabetes mellitus, genetics, genome-wide association study, macular disorders, meta-analysis, single nucleotide polymorphism, genotype determination, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):55. https://doi.org/10.1167/iovs.66.3.55

Includes: Supplemental Content

Retinal Cell Biology November 2024

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

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Jimin Han; Sueanne Chear; Jana Talbot; Vicki Swier; Clarissa Booth; Cheyenne Reuben-Thomas; Sonal Dalvi; Jill M. Weimer; Alex W. Hewitt; Anthony L. Cook; Ruchira Singh
TAGS: autofluorescence, phagocytosis, photoreceptors, platypnea orthodeoxia syndrome, retinal pigment cell, tissue degeneration, genetics, lipofuscin, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):23. https://doi.org/10.1167/iovs.65.13.23

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Polygenic risk is associated with differential treatment response to SLT and medical therapy in treatment-naive glaucoma

Jamie E Craig; Antonia Kolovos; Thi Thi Nguyen; Joshua Schmidt; Stuart L Graham; Alex W Hewitt; Owen Siggs; Stuart MacGregor; Mark Hassall

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1012.

ARVO Annual Meeting Abstract June 2024

Sleep Apnoea Syndrome Correlated with Progression of Normal Tension Glaucoma

Ella Claire Berry; Henry Marshall; Mark Hassall; Antonia Kolovos; Joshua Schmidt; Sean Mullany; Stewart Lake; Anna Galanopoulos; John Landers; Paul Healey; Stuart L Graham; Alex W Hewitt; Stuart MacGregor; Robert Casson; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2766.

ARVO Annual Meeting Abstract June 2024

Iso-seq enables discovery of novel isoform variants in human retina at single cell resolution

Raymond Wong; Luozixian Wang; Daniel Urrutia-Cabrera; Sandy Shen-Chi Hung; Alex W Hewitt; Sam Lukowski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4694.

ARVO Annual Meeting Abstract June 2024

High glaucoma polygenic risk is strongly associated with development of glaucoma in patients with pseudoexfoliation syndrome

Antonia Kolovos; Ayub Qassim; Mark Hassall; Weixiong He; Henry Marshall; Stuart L Graham; Robert James Casson; Richard A Mills; Stewart Lake; Alex W Hewitt; Kathryn Burdon; Joshua Schmidt; Stuart MacGregor; Emmanuelle Souzeau; Owen Siggs; Jamie Craig

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4058.

Glaucoma June 2024

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

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Abadh K. Chaurasia; Stuart MacGregor; Jamie E. Craig; David A. Mackey; Alex W. Hewitt
TAGS: datasets, glaucoma, optic disk, optic nerve disorders, deep learning, training
Trans. Vis. Sci. Tech.. 2024; 13(6):1. https://doi.org/10.1167/tvst.13.6.1

Includes: Supplemental Content

Refractive Intervention August 2023

Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors

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Vinay Kumar Nilagiri; Samantha Sze-Yee Lee; Gareth Lingham; Jason Charng; Seyhan Yazar; Alex W. Hewitt; Lyn R. Griffiths; Paul G. Sanfilippo; Tzu-Hsun Tsai; David A. Mackey
TAGS: ethnic group, refractive errors, myopia, eye
Trans. Vis. Sci. Tech.. 2023; 12(8):14. https://doi.org/10.1167/tvst.12.8.14

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Distribution of axial length in Australians of different age groups, ethnicities, and refractive errors

Vinay Kumar Nilagiri; Samantha Sze-Yee Lee; Gareth Lingham; Jason Charng; Seyhan Yazar; Alex W Hewitt; Lyn Griffiths; Paul Sanfilippo; Tzu-Hsun Tsai; David Mackey

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):831.

Clinical and Epidemiologic Research March 2023

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

PDF

Ella C. Berry; Henry N. Marshall; Sean Mullany; Santiago Diaz Torres; Joshua Schmidt; Daniel Thomson; Lachlan S. W. Knight; Georgina L. Hollitt; Ayub Qassim; Bronwyn Ridge; Angela Schulz; Mark M. Hassall; Thi Thi Nguyen; Stewart Lake; Richard A. Mills; Ashish Agar; Anna Galanopoulos; John Landers; Paul R. Healey; Stuart L. Graham; Alex W. Hewitt; Stuart MacGregor; Robert J. Casson; Owen M. Siggs; Jamie E. Craig
TAGS: cohort studies, physical activity, biobanks
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):11. https://doi.org/10.1167/iovs.64.3.11

Includes: Supplemental Content

Glaucoma October 2022

Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals

PDF

Georgina L. Hollitt; Owen M. Siggs; Bronwyn Ridge; Miriam C. Keane; David A. Mackey; Stuart MacGregor; Alex W. Hewitt; Jamie E. Craig; Emmanuelle Souzeau
TAGS: genetic risk, glaucoma, attitude
Trans. Vis. Sci. Tech.. 2022; 11(10):38. https://doi.org/10.1167/tvst.11.10.38

Includes: Supplemental Content

Retina July 2022

The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

PDF

Kathleen I. C. Dyer; Paul G. Sanfilippo; Seyhan Yazar; Jamie E. Craig; Alex W. Hewitt; John P. Newnham; David A. Mackey; Samantha S. Y. Lee
TAGS: cohort studies, fetal growth, retinal nerve fiber layer, young adult, pregnancy, birth weight, fetus
Trans. Vis. Sci. Tech.. 2022; 11(7):8. https://doi.org/10.1167/tvst.11.7.8

Includes: Supplemental Content

Genetics June 2022

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

PDF

Terri L. Young; Kristina N. Whisenhunt; Sarah M. LaMartina; Alex W. Hewitt; David A. Mackey; Stuart W. Tompson
TAGS: cataract, childhood, cortical cataract, introns, pediatrics, shh gene, enhancer of transcription, genes, genetic pedigree
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):25. https://doi.org/10.1167/iovs.63.6.25

ARVO Annual Meeting Abstract June 2022

The APOE E4 allele is associated with faster rates of mGCIPL thinning in the PROGRESSA cohort

Sean Mullany; Henry Marshall; Emmanuelle Souzeau; Mark Hassall; Ashish Agar; Anna Galanopoulos; John Landers; Paul Mitchell; Paul Healey; Stuart L Graham; Alex W Hewitt; Stuart MacGregor; Puya Gharahkhani; Robert Casson; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1658 – A0153.

ARVO Annual Meeting Abstract June 2022

Change in peripapillary retinal nerve fibre layer thickness from 20 to 28 years old

Samantha Sze-Yee Lee; Alex W Hewitt; David A Mackey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1629 – A0124.

ARVO Annual Meeting Abstract June 2022

Investigating photoreceptor outer segment phagocytosis by retinal pigment epithelium in CLN3-Batten

Jimin Han; Katherine A White; Sueanne Chear; Jana Talbot; Whitney Spencer; Cheyenne I Thomas; Vicki Swier Mosher; Tyler B Johnson; Alex W Hewitt; Anthony L Cook; Jill M Weimer; Ruchira Singh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2442 – F0386.

ARVO Annual Meeting Abstract June 2022

High polygenic risk is associated with earlier treatment initiation and escalation in glaucoma suspects

Henry Marshall; Xikun Han; Sean Mullany; Georgie Hollitt; Ella Claire Berry; Lachlan Knight; Richard A Mills; John Landers; Paul Healey; Alex W Hewitt; Stuart L Graham; Robert Casson; Stuart MacGregor; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4018 – A0360.

ARVO Annual Meeting Abstract June 2022

A polygenic risk score predicts functional progression in early primary open-angle glaucoma

Owen Siggs; Ayub Qassim; Xikun Han; Henry Marshall; Sean Mullany; Emmanuelle Souzeau; Anna Galanopoulos; Ashish Agar; John Landers; Robert Casson; Alex W Hewitt; Paul Healey; Stuart L Graham; Stuart MacGregor; Jamie Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4011 – A0353.

ARVO Annual Meeting Abstract June 2022

Generation of a CRISPRi RPE model to study age-related macular degeneration genetics

Raymond Wong; Jiang Hui Wang; Daniel Urrutia-Cabrera; Jarmon Lees; Santiago Mesa Mora; Tu Nguyen; Sandy Shen-Chi Hung; Alex W Hewitt; Thomas Edwards

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4607 – F0399.

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Longitudinal Change in Retinal Nerve Fiber Layer Thickness and Intraocular Pressure in Young Adults

Genome-Wide Association Study to Identify Genetic Variants Associated With Diabetic Maculopathy

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

Polygenic risk is associated with differential treatment response to SLT and medical therapy in treatment-naive glaucoma

Sleep Apnoea Syndrome Correlated with Progression of Normal Tension Glaucoma

Iso-seq enables discovery of novel isoform variants in human retina at single cell resolution

High glaucoma polygenic risk is strongly associated with development of glaucoma in patients with pseudoexfoliation syndrome

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors

Distribution of axial length in Australians of different age groups, ethnicities, and refractive errors

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals

The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

The APOE E4 allele is associated with faster rates of mGCIPL thinning in the PROGRESSA cohort

Change in peripapillary retinal nerve fibre layer thickness from 20 to 28 years old

Investigating photoreceptor outer segment phagocytosis by retinal pigment epithelium in CLN3-Batten

High polygenic risk is associated with earlier treatment initiation and escalation in glaucoma suspects

A polygenic risk score predicts functional progression in early primary open-angle glaucoma

Generation of a CRISPRi RPE model to study age-related macular degeneration genetics

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