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ARVO Annual Meeting Abstract June 2020

Longitudinal Analysis of Murine Visual Function in Experimental Autoimmune Uveitis (EAU)

Kristin Hösel; Jan Tode; Markus Stöcker; Elisabeth Richert; Alexa Klettner; Stefan Rose-John; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3680. doi:

ARVO Annual Meeting Abstract June 2020

Inflammatory Processes Following Thermal Stimulation of the Retina (TSR) and Selective Retina Therapy (SRT) in AMD Mouse Models

Jan Tode; Elisabeth Richert; Claus von der Burchard; Ralf Brinkmann; Alexa Klettner; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1352. doi:

Articles November 2019

Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models

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Jan Tode; Elisabeth Richert; Stefan Koinzer; Alexa Klettner; Claus von der Burchard; Ralf Brinkmann; Ralph Lucius; Johann Roider
TAGS: age-related macular degeneration, biological response modifiers, eye, mice, retina, bruch's basal membrane, retinal pigment epithelium, pathology, apolipoprotein e
Trans. Vis. Sci. Tech.. 2019; 8(6):11. doi: https://doi.org/10.1167/tvst.8.6.11

ARVO Annual Meeting Abstract July 2019

Unexplained visual loss under silicone oil tamponade: Absorption of silicone oil droplets and proinflammatory response in retinal microglia cells

Johann Roider; Antonia Harms; Vicki Waetzig; Jan Tode; Konstantine Purtskhvanidze; Alexa Klettner

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6610. doi:

ARVO Annual Meeting Abstract July 2019

Drusen-like Retinal Spots in NRF2-/- AMD Mouse Model correlate either to epi-RPE or sub BrM localization

Kristin Hösel; Jan Tode; Elisabeth Richert; Claus von der Burchard; Alexa Klettner; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2992. doi:

ARVO Annual Meeting Abstract July 2018

Effect of two Laser Treatments on Bruchs Membrane Thickness in a Mouse Model of Age-related Macular Degeneration

Elisabeth Richert; Jan Tode; Katharina Vinh; Alexa Karina Klettner; Stefan Otto Johannes Koinzer; Ralph Lucius; Ralf Brinkmann; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):66. doi:

Articles May 2018

Thermal Stimulation of the Retina Reduces Bruch's Membrane Thickness in Age Related Macular Degeneration Mouse Models

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Jan Tode; Elisabeth Richert; Stefan Koinzer; Alexa Klettner; Claus von der Burchard; Ralf Brinkmann; Ralph Lucius; Johann Roider
TAGS: age-related macular degeneration, biological response modifiers, bruch's basal membrane, mice, retina, eye, lasers, laser therapy
Trans. Vis. Sci. Tech.. 2018; 7(3):2. doi: https://doi.org/10.1167/tvst.7.3.2

Retinal Cell Biology March 2018

Release of Different Cell Mediators During Retinal Pigment Epithelium Regeneration Following Selective Retina Therapy

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Elisabeth Richert; Stefan Koinzer; Jan Tode; Kerstin Schlott; Ralf Brinkmann; Jost Hillenkamp; Alexa Klettner; Johann Roider
TAGS: biological response modifiers, bodily secretions, choroid, did not receive therapy or drug, fluorescent antibody technique, gelatinase a, lasers, matrix metalloproteinases, retina, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1323-1331. doi: https://doi.org/10.1167/iovs.17-23163

ARVO Annual Meeting Abstract June 2017

Long term effects of repetitive administration of VEGF-antagonists on primary RPE cells – comparison between Ranibizumab, Bevacizumab and Aflibercept

Alexa Klettner; Johann Schottler; Niklas Randoll; Amke Caliebe; Ralph Lucius; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):873. doi:

ARVO Annual Meeting Abstract June 2017

Reduction of Bruchs Membrane (BrM) Thickness after Pulsed Laser Irradiation in Apolipoprotein (Apo) E Knock Out Mice

Elisabeth Richert; Jan Tode; Alexa Klettner; Stefan Otto Johannes Koinzer; Ralf Brinkmann; Jost Hillenkamp; Ralph Lucius; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1938. doi:

ARVO Annual Meeting Abstract June 2017

CRB-1 rd8 Mutation Influences the Extent of AMD-like Retinal Alterations in NRF2 Knock Out Mice and Favors CNV Formation

Jan Tode; Elisabeth Richert; Alexa Klettner; Claus Christian von der Burchard; Stefan Otto Johannes Koinzer; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1989. doi:

ARVO Annual Meeting Abstract June 2017

The barrier function, autophagy and inflammatory responses are similar under diabetic stimuli in retinal pigment epithelial cells derived from human induced pluripotent stem cells from the diabetic patients and the normal controls

Kati M Juuti-Uusitalo; Alexa Klettner; Elisabeth Richert; Mostafa Kiamehr; Arto Koistinen; Katriina Aalto-Setälä; Kai Kaarniranta; Heli Skottman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2518. doi:

ARVO Annual Meeting Abstract June 2017

Semaphorin 3F expression pattern in outer retina and RPE

Bertan Cakir; Johanna Walz; Anima D Buehler; Hansjuergen Agostini; Gunther R Schlunck; Alexa Klettner; Andreas Stahl

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):233. doi:

ARVO Annual Meeting Abstract September 2016

Laser Thermal Stimulation of the Retina (TS-R) reduces Thickness of Bruch’s Membrane (BrM) in Apolipoprotein (Apo) E knock out Mice

Jan Tode; Elisabeth Richert; Alexa Karina Klettner; Ralf Brinkmann; Stefan Koinzer; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4424. doi:

ARVO Annual Meeting Abstract September 2016

Response of RPE-Choroid Explants to Thermal Stimulation Therapy of the Retinal Pigment Epithelium (TS-R)

Elisabeth Richert; Stefan Koinzer; Alexa Karina Klettner; Ralf Brinkmann; Jost Hillenkamp; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4442. doi:

Biochemistry and Molecular Biology September 2016

The Antiproliferative Effect of Bevacizumab on Human Tenon Fibroblasts Is Not Mediated by Vascular Endothelial Growth Factor Inhibition

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Charlotte V. Fischer; Viktoria Mans; Maren Horn; Sabine Naxer; Alexa Klettner; Christian van Oterendorp
TAGS: bevacizumab, fibroblasts, vascular endothelial growth factor a, antibodies, cell culture techniques, immunoglobulin g, mass or substance concentration per volume
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4970-4977. doi: https://doi.org/10.1167/iovs.16-19938

Retinal Cell Biology October 2015

Effects of Cytokine Activation and Oxidative Stress on the Function of the Human Embryonic Stem Cell–Derived Retinal Pigment Epithelial Cells

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Kati Juuti-Uusitalo; Monica Nieminen; Felix Treumer; Minna Ampuja; Anne Kallioniemi; Alexa Klettner; Heli Skottman
TAGS: cell lines, cytokine, embryonic stem cells, gelatinase a, genes, oxidative stress, proteins, retinal pigment cell, tumor necrosis factors, stromelysin 1
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6265-6274. doi: https://doi.org/10.1167/iovs.15-17333

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Pre-analytical parameters have significant impacts on VEGF levels measured from human plasma

Johanna Madeleine Walz; Daniel Boehringer; Heidrun L Deissler; Peter Heiduschka; Alexa Klettner; Tim U. Krohne; Focke Ziemssen; Andreas Stahl

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):235. doi:

ARVO Annual Meeting Abstract June 2015

Influence of VEGF isoforms and VEGF inhibition on uveal melanoma cell lines - implications for therapeutic VEGF inhibition

Alexa Karina Klettner; Michaela Dithmer; Anna Maria Kirsch; Lidia Graefenstein; Sarah E Coupland; Johann Roider

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5315. doi:

ARVO Annual Meeting Abstract June 2015

Intracellular uptake of therapeutic immunoglobulins and fusion proteins: Comparison between Aflibercept, Bevacizumab and Rituximab

Michaela Dithmer; Johann Roider; Alexa Karina Klettner

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):835. doi:

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Longitudinal Analysis of Murine Visual Function in Experimental Autoimmune Uveitis (EAU)

Inflammatory Processes Following Thermal Stimulation of the Retina (TSR) and Selective Retina Therapy (SRT) in AMD Mouse Models

Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models

Unexplained visual loss under silicone oil tamponade: Absorption of silicone oil droplets and proinflammatory response in retinal microglia cells

Drusen-like Retinal Spots in NRF2-/- AMD Mouse Model correlate either to epi-RPE or sub BrM localization

Effect of two Laser Treatments on Bruchs Membrane Thickness in a Mouse Model of Age-related Macular Degeneration

Thermal Stimulation of the Retina Reduces Bruch's Membrane Thickness in Age Related Macular Degeneration Mouse Models

Release of Different Cell Mediators During Retinal Pigment Epithelium Regeneration Following Selective Retina Therapy

Long term effects of repetitive administration of VEGF-antagonists on primary RPE cells – comparison between Ranibizumab, Bevacizumab and Aflibercept

Reduction of Bruchs Membrane (BrM) Thickness after Pulsed Laser Irradiation in Apolipoprotein (Apo) E Knock Out Mice

CRB-1 rd8 Mutation Influences the Extent of AMD-like Retinal Alterations in NRF2 Knock Out Mice and Favors CNV Formation

The barrier function, autophagy and inflammatory responses are similar under diabetic stimuli in retinal pigment epithelial cells derived from human induced pluripotent stem cells from the diabetic patients and the normal controls

Semaphorin 3F expression pattern in outer retina and RPE

Laser Thermal Stimulation of the Retina (TS-R) reduces Thickness of Bruch’s Membrane (BrM) in Apolipoprotein (Apo) E knock out Mice

Response of RPE-Choroid Explants to Thermal Stimulation Therapy of the Retinal Pigment Epithelium (TS-R)

The Antiproliferative Effect of Bevacizumab on Human Tenon Fibroblasts Is Not Mediated by Vascular Endothelial Growth Factor Inhibition

Effects of Cytokine Activation and Oxidative Stress on the Function of the Human Embryonic Stem Cell–Derived Retinal Pigment Epithelial Cells

Pre-analytical parameters have significant impacts on VEGF levels measured from human plasma

Influence of VEGF isoforms and VEGF inhibition on uveal melanoma cell lines - implications for therapeutic VEGF inhibition

Intracellular uptake of therapeutic immunoglobulins and fusion proteins: Comparison between Aflibercept, Bevacizumab and Rituximab

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