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Retina March 2023

Homozygous Knockout of Cep250 Leads to a Relatively Late-Onset Retinal Degeneration and Sensorineural Hearing Loss in Mice

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Alaa Abu-Diab; Prakadeeswari Gopalakrishnan; Chen Matsevich; Marije de Jong; Alexey Obolensky; Ayat Khalaileh; Manar Salameh; Ayala Ejzenberg; Menachem Gross; Eyal Banin; Dror Sharon; Samer Khateb
TAGS: homozygote, mice, retinal degeneration, sensorineural hearing loss, mice, knockout, retina
Trans. Vis. Sci. Tech.. 2023; 12(3):3. https://doi.org/10.1167/tvst.12.3.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Identification of autosomal recessive novel genes and retinal phenotypes in members of the solute carrier (SLC) superfamily

Dror Sharon; Talya Millo; Jose Antonio Rivera; Alexey Obolensky; Dvorah Marks-Ohana; Enosh Wilhelm; Prakadee Gopalakrish; Menachem Gross; Boris Rosin; Mor Hanany; Anna Maria Tracewska; Ora Schueler-Furman; Susanne Roosing; Eyal Banin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2623.

ARVO Annual Meeting Abstract June 2022

Relatively Slow Retinal Degeneration Process in a Fam161a Knock-in (KI) Mouse Model for the Human Nonsense Mutation p.Arg 523 *

Prakadeeswari Gopalakrishnan; Chen Matsevich; Eyal Banin; Dror Sharon; Avigail Beryozkin; Alexey Obolensky

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2588 – F0471.

ARVO Annual Meeting Abstract July 2019

Subretinal survival of retinal progenitors (RPs) derived from human embryonic stem cells (hESCs) in different animal models

Hamzah Aweidah; Alexey Obolensky; Ayala Ejzenberg; Chen Matsevich; Masha Idelson; Hanita Khaner; Benjamin Reubinoff; Eyal Banin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2891.

ARVO Annual Meeting Abstract July 2019

Novel recombinant Adeno-Associated Virus transfects photoreceptor cells following intravitreal injection in sheep.

Maya Ross; Eyal Banin; Edward Averbukh; Melissa Desrosiers; Alexey Obolensky; Raaya Ezra-Elia; Hen Honig; Esther Yamin; Alexasnder Rosov; Hay Dvir; Elisha Gootwine; Deniz Dalkara; Ron Ofri

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2897.

ARVO Annual Meeting Abstract July 2019

Subretinal and Intravitreal Delivery of the Photoreceptor-Specific AAV2-7m8-hGRK1-GFP Viral Vector in Mice

Chen Matsevich; Deniz Dalkara; Alexey Obolensky; Melissa Desrosiers; Ayala Ejzenberg; Dror Sharon; Eyal Banin; Avigail Beryozkin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2924.

ARVO Annual Meeting Abstract June 2017

Phase I/IIa clinical trial of human embryonic stem cell (hESC)-derived retinal pigmented epithelium (RPE, OpRegen ® ) transplantation in advanced dry form age-related macular degeneration (AMD): interim results

Eyal Banin; Yitzchak Hemo; Tareq Jaouni; Devora Marks-Ohana; Shelly Stika; Svetlana Zheleznykov; Alexey Obolensky; Maria Gurevich; Charles S/ Irving; Benjamin Reubinoff

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2320.

ARVO Annual Meeting Abstract June 2017

Clinical Characteristics of a Large Cohort of Patients with Retinitis Pigmentosa due to Biallelic FAM161A Mutations

Avigail Beryozkin; Samer Khateb; Carlos Idrobo; Mor Hanany; Alexey Obolensky; Dror Sharon; Eyal Banin

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3219.

Retina April 2017

Course of Sodium Iodate–Induced Retinal Degeneration in Albino and Pigmented Mice

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Guy Chowers; Matan Cohen; Devora Marks-Ohana; Shelly Stika; Ayala Eijzenberg; Eyal Banin; Alexey Obolensky
TAGS: albinism, iodates, mice, retinal degeneration, sodium, photoreceptors, injections, electroretinography, mice, inbred c57bl, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2239-2249. https://doi.org/10.1167/iovs.16-21255

Includes: Supplemental Content

Genetics March 2017

Gene Augmentation Therapy for a Missense Substitution in the cGMP-Binding Domain of Ovine CNGA3 Gene Restores Vision in Day-Blind Sheep

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Elisha Gootwine; Mazen Abu-Siam; Alexey Obolensky; Alex Rosov; Hen Honig; Tali Nitzan; Andrey Shirak; Raaya Ezra-Elia; Esther Yamin; Eyal Banin; Edward Averbukh; William W. Hauswirth; Ron Ofri; Eyal Seroussi
TAGS: blindness, cyclic gmp, genes, mutation, sheep, vision, erg protein, human, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1577-1584. https://doi.org/10.1167/iovs.16-20986

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract September 2016

Generation and characterization of Fam161a Conditional Knockout mice

Avigail Beryozkin; Alexey Obolensky; Segev Meyer; Ayala Ejzenberg; Chen Matsevich; Yvan Arsenijevic; Carlo Rivolta; Eyal Banin; Dror Sharon

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3151.

ARVO Annual Meeting Abstract September 2016

Whole exome sequencing reveals a homozygous splicing mutation in CEP78 as the cause of atypical Usher syndrome in Eastern Jewish patients

Dror Sharon; Prasanthi Namburi; Rinki Ratnapriya; Csilla Lazar; Alexey Obolensky; Tamar Ben-Yosef; Eran Pras; Menachem Gross; Eyal Banin; Anand Swaroop

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3153.

ARVO Annual Meeting Abstract September 2016

Gene Augmentation Therapy Restores Retinal Function and Visual Behavior in a Sheep Model of CNGA3 Achromatopsia – Long Term Follow-up

Raaya Ezra-Elia; Elisha Gootwine; Edward Averbukh; Alexey Obolensky; Alexander Rosov; Hen Honig; Shai Sandalon; William Hauswirth; Eyal Banin; Ron Ofri

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5149.

ARVO Annual Meeting Abstract April 2014

GENE THERAPY IN A SHEEP MODEL OF CNGA3 ACHROMATOPSIA

Eyal Banin; Alexey Obolensky; Ayala Ejzenberg; Lina Zelinger; Raaya Ezra-Elia; Alexander Rosov; Edward Averbukh; Elisha Gootwine; Ron Ofri; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4566.

ARVO Annual Meeting Abstract June 2013

RECOVERY OF VISUAL FUNCTION FOLLOWING GENE THERAPY IN A LARGE ANIMAL MODEL OF CNGA3 ACHROMATOPSIA

Edward Averbukh; Ron Ofri; Elisha Gootwine; Raaya Ezra-Elia; Hen Honig; Alexander Rosov; Esther Yamin; Alexey Obolensky; William Hauswirth; Eyal Banin

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2708.

ARVO Annual Meeting Abstract June 2013

Phase I Gene Therapy Trial in Israeli Patients with Leber Congenital Amaurosis Caused by a Founder RPE65 Mutation: Safety and Efficacy Update with Up to Two Years of Follow-up

Eyal Banin; Alexey Obolensky; Yitzhak Hemo; Devora Marks-Ohana; Malka Sela; Esther Yamin; William Hauswirth; Samuel Jacobson; Dror Sharon

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2709.

ARVO Annual Meeting Abstract June 2013

Age-Dependent Ocular Changes in Sirt6 Knockout Mice

Alexey Obolensky; Victoria Peshti; Yariv Kanfi; Haim Cohen; Eyal Banin

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6078.

ARVO Annual Meeting Abstract March 2012

FAM161A Produces Two Protein Isoforms with a Differential Retinal Expression Pattern

Dror Sharon; Alexey Obolensky; Elia Shevach; Eyal Banin; Shahar Frenkel; Adi Inbal; Dikla Bandah-Rozenfeld

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1618.

Retina February 2012

Retinal Function and Structure in the Hypotransferrinemic Mouse

PDF

Michal Lederman; Alexey Obolensky; Michelle Grunin; Eyal Banin; Itay Chowers
TAGS: iron, mice, proteins, retina, rna, messenger, transferrin, ophthalmoscopy, genes
Invest. Ophthalmol. Vis. Sci.. 2012; 53(2):605-612. https://doi.org/10.1167/iovs.11-7436

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

Mutation Survey of FAM161A in Patients with Retinitis Pigmentosa and Analysis of Protein Localization in the Human Retina

Dror Sharon; Dikla Bandah-Rozenfeld; Alexey Obolensky; Liliana Mizrahi-Meissonnier; Tamar Ben-Yosef; Sharon B. Schwartz; Artur V. Cideciyan; Samuel G. Jacobson; Eyal Banin

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5388.

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Homozygous Knockout of Cep250 Leads to a Relatively Late-Onset Retinal Degeneration and Sensorineural Hearing Loss in Mice

Identification of autosomal recessive novel genes and retinal phenotypes in members of the solute carrier (SLC) superfamily

Relatively Slow Retinal Degeneration Process in a Fam161a Knock-in (KI) Mouse Model for the Human Nonsense Mutation p.Arg 523 *

Subretinal survival of retinal progenitors (RPs) derived from human embryonic stem cells (hESCs) in different animal models

Novel recombinant Adeno-Associated Virus transfects photoreceptor cells following intravitreal injection in sheep.

Subretinal and Intravitreal Delivery of the Photoreceptor-Specific AAV2-7m8-hGRK1-GFP Viral Vector in Mice

Phase I/IIa clinical trial of human embryonic stem cell (hESC)-derived retinal pigmented epithelium (RPE, OpRegen ® ) transplantation in advanced dry form age-related macular degeneration (AMD): interim results

Clinical Characteristics of a Large Cohort of Patients with Retinitis Pigmentosa due to Biallelic FAM161A Mutations

Course of Sodium Iodate–Induced Retinal Degeneration in Albino and Pigmented Mice

Gene Augmentation Therapy for a Missense Substitution in the cGMP-Binding Domain of Ovine CNGA3 Gene Restores Vision in Day-Blind Sheep

Generation and characterization of Fam161a Conditional Knockout mice

Whole exome sequencing reveals a homozygous splicing mutation in CEP78 as the cause of atypical Usher syndrome in Eastern Jewish patients

Gene Augmentation Therapy Restores Retinal Function and Visual Behavior in a Sheep Model of CNGA3 Achromatopsia – Long Term Follow-up

GENE THERAPY IN A SHEEP MODEL OF CNGA3 ACHROMATOPSIA

RECOVERY OF VISUAL FUNCTION FOLLOWING GENE THERAPY IN A LARGE ANIMAL MODEL OF CNGA3 ACHROMATOPSIA

Phase I Gene Therapy Trial in Israeli Patients with Leber Congenital Amaurosis Caused by a Founder RPE65 Mutation: Safety and Efficacy Update with Up to Two Years of Follow-up

Age-Dependent Ocular Changes in Sirt6 Knockout Mice

FAM161A Produces Two Protein Isoforms with a Differential Retinal Expression Pattern

Retinal Function and Structure in the Hypotransferrinemic Mouse

Mutation Survey of FAM161A in Patients with Retinitis Pigmentosa and Analysis of Protein Localization in the Human Retina

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