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ARVO Annual Meeting Abstract June 2025

Specializing vision-language models for the clinical management of age-related macular degeneration

Martin Menten; Robbie Holland; Tom Taylor; Christopher Holmes; Sophie Riedl; Julia Mai; Maria Patsiamanidi; Dimitra Mitsopoulou; Paul Hager; Philip Müller; Johannes Paetzold; Hendrik P Scholl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Daniel Rückert; Sobha Sivaprasad; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):863.

ARVO Annual Meeting Abstract June 2025

Investigating the role of GNGT2-mediated GPCR signalling in cone development

Catherine Robertson; Delphine Boche; Andrew J Lotery; Jörn Lakowski

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5317.

ARVO Annual Meeting Abstract June 2025

Early life pre-disposition to diet-induced retinal pathology

Anna-Marie Muir; Savannah A Lynn; Eloise Keeling; Helen Griffiths; Sandrine Willaime-Morawek; Neil R Smyth; Helena Lee; Andrew J Lotery; J. Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4823.

ARVO Annual Meeting Abstract June 2025

Functional outcomes across high-risk OCT-based phenotypes in intermediate age-related macular degeneration in the prospective PINNACLE study

Marie Louise Enzendorfer; Julia Mai; Sophie Riedl; Hrvoje Bogunovic; Martin Menten; Daniel Rueckert; Lars G Fritsche; A Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1334.

ARVO Annual Meeting Abstract June 2025

Prototypical Machine Learning for Individual Prediction of Conversion to Atrophic AMD in the PINNACLE Study

Arunava Chakravarty; Julia Mai; Taha Emre; Marie Louise Enzendorfer; Sophie Riedl; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Toby Prevost; Martin Menten; Daniel Rueckert; Andrew J Lotery; Hrvoje Bogunovic; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4086.

ARVO Annual Meeting Abstract June 2025

Pointwise structure-function correlation between focal event-targeted microperimetry and the first sign of conversion to advanced AMD in the PINNACLE study

Sophie Frank; Klaudia Birner; Julia Mai; Sophie Riedl; Magdalena Baratsits; Simon Schürer-Waldheim; Markus Gumpinger; Hrvoje Bogunovic; Manjula Nugawela; Martin Menten; Daniel Rueckert; Lars G Fritsche; Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1340.

ARVO Annual Meeting Abstract June 2025

Studies in the 5xFAD mouse retina reveal chronic Amyloid-beta mediated effects, providing new insights into complex retinopathies

J. Arjuna Ratnayaka; Savannah A Lynn; Sudha Priya Soundara Pandi; Aida Sanchez-Bretano; Anna-Marie Muir; Lidia Parker; David S Chatelet; Tutte Newall; Jenny A Scott; Eloise Keeling; Neil R Smyth; James E Self; Helena Lee; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1180.

ARVO Annual Meeting Abstract June 2025

Pointwise correlation of deep learning-based quantified features of intermediate AMD on OCT and standardized retinal sensitivity in the prospective PINNACLE study

Julia Mai; Sophie Riedl; Louise Enzendorfer; Hrvoje Bogunovic; Martin Menten; Daniel Rueckert; Lars G Fritsche; A Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1075.

Telemedicine March 2024

Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

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Ruth E. Hogg; Robin Wickens; Sean O'Connor; Eleanor Gidman; Elizabeth Ward; Tunde Peto; Benjamen J. L. Burton; Paul Knox; Andrew J. Lotery; Sobha Sivaprasad; Michael Donnelly; Chris A. Rogers; Barnaby C. Reeves
TAGS: exudative age-related macular degeneration, older adult, technology, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(3):2. https://doi.org/10.1167/tvst.13.3.2

Retina August 2023

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

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Philipp Anders; Ghislaine L. Traber; Maximilian Pfau; Sophie Riedl; Ahmed M. Hagag; Hanna Camenzind; Julia Mai; Rebecca Kaye; Hrvoje Bogunović; Lars G. Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J. Lotery; Hendrik P. N. Scholl
TAGS: age-related macular degeneration, study report, visual acuity, software
Trans. Vis. Sci. Tech.. 2023; 12(8):21. https://doi.org/10.1167/tvst.12.8.21

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ARVO Annual Meeting Abstract June 2023

MacuSIM: An in-vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

J. Arjuna Ratnayaka; David A Johnston; Ben Mills; Andrew J Lotery; Tracey A Newman; Savannah Amy Lynn

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4743.

ARVO Annual Meeting Abstract June 2023

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

Robbie Holland; Oliver Leingang; Ahmed M Hagag; Christopher Holmes; Philipp Anders; Johannes C. C. Paetzold; Rebecca Kaye; Sophie Riedl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Hendrik P Scholl; Daniel Rueckert; Andrew J Lotery; Sobha Sivaprasad; Martin Joseph Menten

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1283.

ARVO Annual Meeting Abstract June 2023

IMPG2 -related maculopathy

Johannes Birtel; Richard Caswell; Samantha R De Silva; Philipp Herrmann; Salwah Rehman; Andrew J Lotery; Omar Abdul Rahman Mahroo; Michel Michaelides; Andrew R Webster; Robert E MacLaren; Peter Charbel Issa

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4643.

ARVO Annual Meeting Abstract June 2023

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Philipp Anders; Ghislaine L Traber; Maximilian Pfau; Sophie Riedl; Julia Mai; Hanna Camenzind; Chrysoula Gabrani; Rebecca Kaye; Toby Prevost; Hrvoje Bogunovic; Lars G Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4328.

ARVO Annual Meeting Abstract June 2023

Intraluminal acidity plays a key role in the function of lysosomes in RPE cells

Rebecca Denise Miller; Savannah Amy Lynn; Eloise Keeling; Charles Ellis; David Chatelet; David A Johnston; David A Tumbarello; Andrew J Lotery; Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3891.

ARVO Annual Meeting Abstract June 2023

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Arunava Chakravarty; Taha Emre; Oliver Leingang; Sophie Riedl; Julia Mai; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Daniel Rueckert; Andrew J Lotery; Ursula Schmidt-Erfurth; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):545.

ARVO Annual Meeting Abstract June 2023

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Oliver Leingang; Hrvoje Bogunovic; Gregor Sebastian Reiter; Arunava Chakravarty; Martin Joseph Menten; Robert Holland; Lars G Fritsche; Hendrik P Scholl; Daniel Rueckert; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):544.

ARVO Annual Meeting Abstract June 2023

Geometric deep learning for disease classification in OCTA images

Johannes C. C. Paetzold; Laurin Lux; Linus Kreitner; Ivan Ezhov; Suprosanna Shit; Andrew J Lotery; Martin Joseph Menten; Daniel Rueckert

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1098.

ARVO Annual Meeting Abstract June 2023

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

Christopher Holmes; Syed Ahmer Raza; Ahmed M Hagag; Thomas Taylor; Sophie Riedl; Julia Mai; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars G Fritsche; Andrew J Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2171.

ARVO Annual Meeting Abstract June 2023

6-year outcomes of the United Kingdom Medisoft® audit study following treatment with the ILUVIEN® (fluocinolone acetonide) implant in patients with diabetic macular edema.

Bushra Mushtaq; Clare C Bailey; Usha Chakravarthy; Andrew J Lotery; James Talks; Geeta Menon

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2651.

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Specializing vision-language models for the clinical management of age-related macular degeneration

Investigating the role of GNGT2-mediated GPCR signalling in cone development

Early life pre-disposition to diet-induced retinal pathology

Functional outcomes across high-risk OCT-based phenotypes in intermediate age-related macular degeneration in the prospective PINNACLE study

Prototypical Machine Learning for Individual Prediction of Conversion to Atrophic AMD in the PINNACLE Study

Pointwise structure-function correlation between focal event-targeted microperimetry and the first sign of conversion to advanced AMD in the PINNACLE study

Studies in the 5xFAD mouse retina reveal chronic Amyloid-beta mediated effects, providing new insights into complex retinopathies

Pointwise correlation of deep learning-based quantified features of intermediate AMD on OCT and standardized retinal sensitivity in the prospective PINNACLE study

Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

MacuSIM: An in-vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

IMPG2 -related maculopathy

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Intraluminal acidity plays a key role in the function of lysosomes in RPE cells

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Geometric deep learning for disease classification in OCTA images

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

6-year outcomes of the United Kingdom Medisoft® audit study following treatment with the ILUVIEN® (fluocinolone acetonide) implant in patients with diabetic macular edema.

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