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ARVO Annual Meeting Abstract June 2024

Patient-tailored Microperimetry Grids for Focal Lesions in Intermediate AMD: A PINNACLE Study Report

Stefan Futterknecht; Maximilian Pfau; Philipp Anders; Julia Mai; Ursula Hall; Hrvoje Bogunovic; Lars Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4386.

ARVO Annual Meeting Abstract June 2024

A clinical study evaluating biomarkers of immunosenescence in the progression of Age-Related Macular Degeneration (The Immuno AMD Study)

Adnan Khan; Andrew Shapanis; Paul Skipp; Andrew Lotery

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):940.

ARVO Annual Meeting Abstract June 2024

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Sophie Riedl; Julia Mai; Simon Schürer-Waldheim; Georg Faustmann; Hrvoje Bogunovic; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hendrik P Scholl; Sobha Sivaprasad; Andrew Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):980.

ARVO Annual Meeting Abstract June 2024

Evaluating the distribution of fundus autofluorescence phenotypes in a large, European intermediate AMD cohort and describing a novel phenotype (A PINNACLE Study Report)

Tom Taylor; Rebecca Anne Kaye; Julia Mai; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2266.

ARVO Annual Meeting Abstract June 2024

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

Christopher Holmes; Naomi Wijesingha; Syed Ahmer Raza; Tom Taylor; Ahmed Hagag; Sophie Riedl; Julia Mai; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars Fritsche; Andrew Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3264.

ARVO Annual Meeting Abstract June 2024

Molecular and Cellular Mechanisms of Levodopa-Mediated Visual Function Rescue in Albinism

Sarah Macdonald; Eloise Keeling; Jennifer A Scott; Helen Griffiths; Andrew Lotery; J. Arjuna Ratnayaka; James Edward Self; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):821.

ARVO Annual Meeting Abstract June 2024

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Tobias Peters; Katarina Stingl; Wolfgang Klein; Mario G Fsadni; Nils Meland; Patty P.A. Dhooge; Camiel Boon; Andrew Lotery; Maurizio Battaglia Parodi; Philipp Herrmann; Frank G Holz; Steffen Schmitz-Valckenberg; Philipp Möller; Carel C B Hoyng

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2205.

ARVO Annual Meeting Abstract June 2024

Real world treatment intervals in eyes with nAMD treated with Aflibercept. Retrospective UK multicentre study.

Peter Henry Scanlon; Marta Gruszka-Goh; Sharam Kashani; Martin McKibbin; Andrew Lotery; Romi Chhabra; James Talks; Quresh Mohamed

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2117.

Telemedicine March 2024

Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

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Ruth E. Hogg; Robin Wickens; Sean O'Connor; Eleanor Gidman; Elizabeth Ward; Tunde Peto; Benjamen J. L. Burton; Paul Knox; Andrew J. Lotery; Sobha Sivaprasad; Michael Donnelly; Chris A. Rogers; Barnaby C. Reeves
TAGS: exudative age-related macular degeneration, older adult, technology, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(3):2. https://doi.org/10.1167/tvst.13.3.2

Retina August 2023

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

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Philipp Anders; Ghislaine L. Traber; Maximilian Pfau; Sophie Riedl; Ahmed M. Hagag; Hanna Camenzind; Julia Mai; Rebecca Kaye; Hrvoje Bogunović; Lars G. Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J. Lotery; Hendrik P. N. Scholl
TAGS: age-related macular degeneration, study report, visual acuity, software
Trans. Vis. Sci. Tech.. 2023; 12(8):21. https://doi.org/10.1167/tvst.12.8.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

MacuSIM: An in-vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

J. Arjuna Ratnayaka; David A Johnston; Ben Mills; Andrew J Lotery; Tracey A Newman; Savannah Amy Lynn

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4743.

ARVO Annual Meeting Abstract June 2023

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

Robbie Holland; Oliver Leingang; Ahmed M Hagag; Christopher Holmes; Philipp Anders; Johannes C. C. Paetzold; Rebecca Kaye; Sophie Riedl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Hendrik P Scholl; Daniel Rueckert; Andrew J Lotery; Sobha Sivaprasad; Martin Joseph Menten

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1283.

ARVO Annual Meeting Abstract June 2023

IMPG2 -related maculopathy

Johannes Birtel; Richard Caswell; Samantha R De Silva; Philipp Herrmann; Salwah Rehman; Andrew J Lotery; Omar Abdul Rahman Mahroo; Michel Michaelides; Andrew R Webster; Robert E MacLaren; Peter Charbel Issa

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4643.

ARVO Annual Meeting Abstract June 2023

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Philipp Anders; Ghislaine L Traber; Maximilian Pfau; Sophie Riedl; Julia Mai; Hanna Camenzind; Chrysoula Gabrani; Rebecca Kaye; Toby Prevost; Hrvoje Bogunovic; Lars G Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4328.

ARVO Annual Meeting Abstract June 2023

Intraluminal acidity plays a key role in the function of lysosomes in RPE cells

Rebecca Denise Miller; Savannah Amy Lynn; Eloise Keeling; Charles Ellis; David Chatelet; David A Johnston; David A Tumbarello; Andrew J Lotery; Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3891.

ARVO Annual Meeting Abstract June 2023

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Arunava Chakravarty; Taha Emre; Oliver Leingang; Sophie Riedl; Julia Mai; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Daniel Rueckert; Andrew J Lotery; Ursula Schmidt-Erfurth; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):545.

ARVO Annual Meeting Abstract June 2023

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Oliver Leingang; Hrvoje Bogunovic; Gregor Sebastian Reiter; Arunava Chakravarty; Martin Joseph Menten; Robert Holland; Lars G Fritsche; Hendrik P Scholl; Daniel Rueckert; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):544.

ARVO Annual Meeting Abstract June 2023

Geometric deep learning for disease classification in OCTA images

Johannes C. C. Paetzold; Laurin Lux; Linus Kreitner; Ivan Ezhov; Suprosanna Shit; Andrew J Lotery; Martin Joseph Menten; Daniel Rueckert

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1098.

ARVO Annual Meeting Abstract June 2023

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

Christopher Holmes; Syed Ahmer Raza; Ahmed M Hagag; Thomas Taylor; Sophie Riedl; Julia Mai; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars G Fritsche; Andrew J Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2171.

ARVO Annual Meeting Abstract June 2023

6-year outcomes of the United Kingdom Medisoft® audit study following treatment with the ILUVIEN® (fluocinolone acetonide) implant in patients with diabetic macular edema.

Bushra Mushtaq; Clare C Bailey; Usha Chakravarthy; Andrew J Lotery; James Talks; Geeta Menon

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2651.

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Patient-tailored Microperimetry Grids for Focal Lesions in Intermediate AMD: A PINNACLE Study Report

A clinical study evaluating biomarkers of immunosenescence in the progression of Age-Related Macular Degeneration (The Immuno AMD Study)

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Evaluating the distribution of fundus autofluorescence phenotypes in a large, European intermediate AMD cohort and describing a novel phenotype (A PINNACLE Study Report)

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

Molecular and Cellular Mechanisms of Levodopa-Mediated Visual Function Rescue in Albinism

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Real world treatment intervals in eyes with nAMD treated with Aflibercept. Retrospective UK multicentre study.

Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

MacuSIM: An in-vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

IMPG2 -related maculopathy

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Intraluminal acidity plays a key role in the function of lysosomes in RPE cells

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Geometric deep learning for disease classification in OCTA images

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

6-year outcomes of the United Kingdom Medisoft® audit study following treatment with the ILUVIEN® (fluocinolone acetonide) implant in patients with diabetic macular edema.

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