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Cornea & External Disease May 2024

Design and Biocompatibility of a Novel, Flexible Artificial Cornea

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Gavin Li; Anthony J. Aldave; Guillermo Amescua; Kathryn A. Colby; Maria S. Cortina; Jose de la Cruz; Jean-Marie A. Parel; Thomas B. Schmiedel; Esen Karamursel Akpek
TAGS: biocompatibility, cornea, optics, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2024; 13(5):19. https://doi.org/10.1167/tvst.13.5.19

Cornea & External Disease August 2023

Twelve-Month Clinical and Histopathological Performance of a Novel Synthetic Cornea Device in Rabbit Model

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Esen Karamursel Akpek; Anthony J. Aldave; Guillermo Amescua; Kathryn A. Colby; Maria S. Cortina; Jose de la Cruz; Jean-Marie A. Parel; Gavin Li
TAGS: cornea, histopathology tests, oryctolagus cuniculus, eye, optics
Trans. Vis. Sci. Tech.. 2023; 12(8):9. https://doi.org/10.1167/tvst.12.8.9

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2022

Novel DCN mutation in Armenian family with Congenital Stromal Corneal Dystrophy

Dominic Williams; Doug Chung; Anna Hovakimyan; Araks Davtyan; Ben Glasgow; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):103 – A0201.

ARVO Annual Meeting Abstract June 2022

Sex Difference in Congenital Hereditary Endothelial Dystrophy and a Slc4a11 -/- mouse model

Wenlin Zhang; Dominic Williams; Onyinye Onyia; Marco Morselli; Matteo Pellegrini; Arthur Arnold; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2283.

ARVO Annual Meeting Abstract June 2022

Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells

Doug Chung; Angela Chen; Charlene Choo; Wenlin Zhang; Christopher Griffis; Paul Bonezzi; Alapakkam P Sampath; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3624 – A0189.

ARVO Annual Meeting Abstract June 2021

Investigation of Oxidative Stress in Ex Vivo Corneal Endothelial Cells During Cell Culture and Expansion

Charlene Choo; Doug Chung; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):814.

Cornea July 2020

Energy Shortage in Human and Mouse Models of SLC4A11 -Associated Corneal Endothelial Dystrophies

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Wenlin Zhang; Ricardo Frausto; Doug D. Chung; Christopher G. Griffis; Liyo Kao; Angela Chen; Rustam Azimov; Alapakkam P. Sampath; Ira Kurtz; Anthony J. Aldave
TAGS: cornea, endothelium, mice, corneal endothelium, rna, endothelial cells
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):39. https://doi.org/10.1167/iovs.61.8.39

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Posterior polymorphous corneal dystrophy: Transcriptomic impact of OVOL2 and GRHL2 overexpression on corneal endothelial cells

Doug Chung; JooYeon Jung; Marco Morselli; Matteo Pellegrini; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1450.

ARVO Annual Meeting Abstract June 2020

The generation of a human corneal endothelial cell model of congenital hereditary endothelial dystrophy using CRISPR-Cas9 gene editing

Kavya Jatavallabhula; Angela Chen; Doug Chung; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4695.

ARVO Annual Meeting Abstract June 2020

Genetic Analysis of a Rare Phenotype Characterized by Corneal Ectasia associated with Posterior Stromal Opacification

Angela Chen; Madeline Yung; Doug Chung; Alice Barrington; Junwei Zhang; Ricardo F Frausto; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2433.

ARVO Annual Meeting Abstract July 2019

Transcriptomic analysis of PPCD and the generation of a cell-based model of PPCD using CRISPR-Cas9 gene editing

Doug Chung; Ricardo F Frausto; Vinay Swamy; Liam Carrigan; Davey Wong; Marco Morselli; Matteo Pellegrini; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2161.

ARVO Annual Meeting Abstract July 2019

Metabolic Reprogramming in Human and Mouse Corneal Endothelial Cells with Reduced Expression of SLC4A11

Wenlin Zhang; Ricardo F Frausto; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3873.

ARVO Annual Meeting Abstract July 2019

Low mitogenic conditions maintain the corneal endothelial cell phenotype in vitro

Payton Boere; Jessica Wu; Ricardo F Frausto; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5413.

ARVO Annual Meeting Abstract July 2019

Punctiform and Polychromatic Pre-Descemet Corneal Dystrophy: report of two families and the identification of a segregating intronic variant in PDZD8 using whole-exome sequencing

Alice Rose Barrington; Doug Chung; Jorge Alio del Barrio; Kavya Jatavallabhula; Vinay Swamy; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5414.

ARVO Annual Meeting Abstract July 2019

ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing

Anthony J Aldave; Ricardo F Frausto; Doug Chung; Vinay Swamy; Huong Duong; Wenlin Zhang; Payton Boere; Marina Zakharevich; Maryam Hanser; Ira Kurtz; Matteo Pellegrini

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5416.

ARVO Annual Meeting Abstract July 2018

Transcriptomic Profiling of SLC4A11 Null Murine Corneal Endothelial Cells

Vinay Swamy; Wenlin Zhang; Ricardo F Frausto; Joseph A Bonanno; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4432.

ARVO Annual Meeting Abstract July 2018

Corneal endothelial dystrophies belong to the same series of disorders connected by transcriptional factors ZEB1 and TCF4/E2-2

Wenlin Zhang; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1351.

ARVO Annual Meeting Abstract July 2018

Factors Affecting Primary Human Corneal Endothelial Cell Adhesion

Ricardo F Frausto; Vinay S Swamy; Doug D Chung; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1373.

ARVO Annual Meeting Abstract July 2018

The impact of CHED- and FECD-associated SLC4A11 mutations on protein localization in human corneal endothelial cells.

Doug D Chung; Anthony J Aldave

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2919.

Cornea June 2017

Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy

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Doug D. Chung; Ricardo F. Frausto; Benjamin R. Lin; Evelyn M. Hanser; Zack Cohen; Anthony J. Aldave
TAGS: cornea, genes, polymorphous corneal dystrophy, proteins, rna, zinc finger e-box-binding homeobox 1, endothelium
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3202-3214. https://doi.org/10.1167/iovs.17-21423

Includes: Supplemental Content

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Design and Biocompatibility of a Novel, Flexible Artificial Cornea

Twelve-Month Clinical and Histopathological Performance of a Novel Synthetic Cornea Device in Rabbit Model

Novel DCN mutation in Armenian family with Congenital Stromal Corneal Dystrophy

Sex Difference in Congenital Hereditary Endothelial Dystrophy and a Slc4a11 -/- mouse model

Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells

Investigation of Oxidative Stress in Ex Vivo Corneal Endothelial Cells During Cell Culture and Expansion

Energy Shortage in Human and Mouse Models of SLC4A11 -Associated Corneal Endothelial Dystrophies

Posterior polymorphous corneal dystrophy: Transcriptomic impact of OVOL2 and GRHL2 overexpression on corneal endothelial cells

The generation of a human corneal endothelial cell model of congenital hereditary endothelial dystrophy using CRISPR-Cas9 gene editing

Genetic Analysis of a Rare Phenotype Characterized by Corneal Ectasia associated with Posterior Stromal Opacification

Transcriptomic analysis of PPCD and the generation of a cell-based model of PPCD using CRISPR-Cas9 gene editing

Metabolic Reprogramming in Human and Mouse Corneal Endothelial Cells with Reduced Expression of SLC4A11

Low mitogenic conditions maintain the corneal endothelial cell phenotype in vitro

Punctiform and Polychromatic Pre-Descemet Corneal Dystrophy: report of two families and the identification of a segregating intronic variant in PDZD8 using whole-exome sequencing

ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing

Transcriptomic Profiling of SLC4A11 Null Murine Corneal Endothelial Cells

Corneal endothelial dystrophies belong to the same series of disorders connected by transcriptional factors ZEB1 and TCF4/E2-2

Factors Affecting Primary Human Corneal Endothelial Cell Adhesion

The impact of CHED- and FECD-associated SLC4A11 mutations on protein localization in human corneal endothelial cells.

Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy

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