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ARVO Annual Meeting Abstract July 2018

Improvement and stabilization of vision for 18 months after Human Embryonic Stem-cell (hESC) derived, RPE-sheet transplantation on a synthetic basement membrane for trestment of severe, wet Age-Related Macular Degeneration

Lyndon daCruz; Kate Fynes; Odysseas Georgiadis; Britta Nommiste; Amanda-Jayne Francis Carr; Conor Ramsden; Anthony Vugler; Paul Whiting; Peter Loudon; Peter J Coffey

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2985.

ARVO Annual Meeting Abstract June 2017

QRX-411, an Antisense Oligonucleotide (AON) Directing Splice Correction in USH2A mRNA Caused by the Frequent Deep-Intronic c.7595-2144A>G Mutation Associated with Retinitis Pigmentosa in Usher Syndrome Type 2

Hester van Diepen; Heelam Chan; Janne Turunen; Ma'ayan Semo; Anthony Vugler; Ralph Slijkerman; Erwin van Wijk; Peter Adamson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1203.

ARVO Annual Meeting Abstract September 2016

QR-110, an RNA oligonucleotide (AON) directing skipping of the cryptic exon in p.Cys998X CEP290 associated with Leber’s congenital amaurosis, shows increase in wild-type mRNA and an ability to reach the outer nuclear layer (ONL) in mice following intravitreal administration

Patricia Biasutto; Hee Lam Chan; Hester Boersma; Thomas Hoogenboezem; Jim Swildens; Kalyan Dulla; Ma'ayan Mary Semo; Anthony Alexander Vugler; Rob Collin; Peter Adamson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1123.

Articles July 2016

Efficacy and Safety of Human Retinal Progenitor Cells

PDF

Ma'ayan Semo; Nasrin Haamedi; Lara Stevanato; David Carter; Gary Brooke; Michael Young; Peter Coffey; John Sinden; Sara Patel; Anthony Vugler
TAGS: dexamethasone, eye, prostate cancer, hormone-refractory, rats, safety, transplantation, vision, stem cells, injections
Trans. Vis. Sci. Tech.. 2016; 5(4):6. https://doi.org/10.1167/tvst.5.4.6

Includes: Supplemental Content

Visual Neuroscience January 2016

Retrograde Melanopsin Signaling Increases With Age in Retinal Degenerate Mice Lacking Rods and the Majority of Cones

PDF

Ma'ayan Semo; Peter Coffey; Carlos Gias; Anthony Vugler
TAGS: melanopsin, mice, retinal cone, signal transduction, retina, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2016; 57(1):115-125. https://doi.org/10.1167/iovs.15-17609

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

RPE65 Fuels the intrinsic pupillary light reflex in mice

Aisling Lynch; Lina Sprogyte; Ma'ayan Semo; Amanda-Jayne Francis Carr; Anthony Vugler

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1710.

ARVO Annual Meeting Abstract June 2015

Transplantation of human retinal progenitor cells into the P23H rat improves the scotopic ERG.

Ma'ayan Semo; Aisling Lynch; Nasrin Haamedi; David Carter; John Sinden; Michael Young; Lara Stevanato; Sara Patel; Anthony Vugler

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1821.

ARVO Annual Meeting Abstract June 2013

Differentiation of iPS-RPE cells from a patient with clinical anophthalmia

Amanda-Jayne Carr; Lena Ho; Li Li Chen; Grace Selva Raj; Anthony Vugler; Mohammad Shboul; Alan Colman; Bruno Reversade; Peter Coffey

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4055.

ARVO Annual Meeting Abstract March 2012

Light Responsiveness Of RPE Derived From Human Embryonic Stem Cells

Lei Zheng; Amanda-Jayne F. Carr; Ma'ayan Semo; Li Li Chen; Mark Hankins; Pete J. Coffey; Anthony A. Vugler

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2696.

Retinal Cell Biology September 2011

Induction of Differentiation by Pyruvate and DMEM in the Human Retinal Pigment Epithelium Cell Line ARPE-19

PDF

Ahmad Ahmado; Amanda-Jayne Carr; Anthony A. Vugler; Ma'ayan Semo; Carlos Gias; Jean M. Lawrence; Li Li Chen; Fred K. Chen; Patric Turowski; Lyndon da Cruz; Peter J. Coffey
TAGS: pyruvates, glucose, cell lines, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2011; 52(10):7148-7159. https://doi.org/10.1167/iovs.10-6374

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

Neural Progenitor Cells Differentiate Into A Glial Lineage After Intravitreal And Subretinal Transplantation In A Degenerating Retinal Environment

Peter Lundh von Leithner; Jean Lawrence; Anthony Vugler; Peter J. Coffey

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2256.

ARVO Annual Meeting Abstract April 2011

Patterns Of Light-mediated C-fos Activity In The Medial Visual Cortex Of Mice Lacking Both Rods And Cones

F Javier Valiente-Soriano; Diego García-Ayuso; Arturo Ortín-Martínez; Ma'ayan Semo; Manuel Jiménez-López; Carlos Gias; Maria Paz Villegas-Pérez; Peter Coffey; Manuel Vidal-Sanz; Anthony A. Vugler

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3464.

ARVO Annual Meeting Abstract April 2011

Population Of Melanopsin-expressing Retinal Ganglion Cells In Aging Wildtype And Rodless/coneless Mice: A Detailed Quantitative And Topographical Analysis

Arturo Ortin-Martinez; Diego García-Ayuso; F Javier Valiente-Soriano; Manuel Jímenez-López; María P. Villegas-Pérez; Marta Agudo-Barriuso; Pete Coffey; Anthony A. Vugler; Manuel Vidal-Sanz; Ma'ayam Semo

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3466.

ARVO Annual Meeting Abstract April 2011

Retinal Markers In The Developing Human Fetal Retinal Pigment Epithelium

Matthew J. Smart; Michael B. Powner; Marcus Fruttiger; Peter J. Coffey; Anthony A. Vugler

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4104.

ARVO Annual Meeting Abstract April 2011

Changes in Extracellular Matrix Components of ARPE-19 Cells by Fenretinide

Amanda-Jayne F. Carr; Anthony A. Vugler; Stephen E. Moss; John Greenwood; Pete Coffey

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):870.

Visual Psychophysics and Physiological Optics June 2008

Real-Time In Vivo Imaging of Retinal Cell Apoptosis after Laser Exposure

PDF

Steffen Schmitz-Valckenberg; Li Guo; Annelie Maass; William Cheung; Anthony Vugler; Stephen E. Moss; Peter M. G. Munro; Frederick W. Fitzke; M. Francesca Cordeiro
TAGS: apoptosis, diagnostic imaging, lasers, retina
Invest. Ophthalmol. Vis. Sci.. 2008; 49(6):2773-2780. https://doi.org/10.1167/iovs.07-1335

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Improvement and stabilization of vision for 18 months after Human Embryonic Stem-cell (hESC) derived, RPE-sheet transplantation on a synthetic basement membrane for trestment of severe, wet Age-Related Macular Degeneration

QRX-411, an Antisense Oligonucleotide (AON) Directing Splice Correction in USH2A mRNA Caused by the Frequent Deep-Intronic c.7595-2144A>G Mutation Associated with Retinitis Pigmentosa in Usher Syndrome Type 2

QR-110, an RNA oligonucleotide (AON) directing skipping of the cryptic exon in p.Cys998X CEP290 associated with Leber’s congenital amaurosis, shows increase in wild-type mRNA and an ability to reach the outer nuclear layer (ONL) in mice following intravitreal administration

Efficacy and Safety of Human Retinal Progenitor Cells

Retrograde Melanopsin Signaling Increases With Age in Retinal Degenerate Mice Lacking Rods and the Majority of Cones

RPE65 Fuels the intrinsic pupillary light reflex in mice

Transplantation of human retinal progenitor cells into the P23H rat improves the scotopic ERG.

Differentiation of iPS-RPE cells from a patient with clinical anophthalmia

Light Responsiveness Of RPE Derived From Human Embryonic Stem Cells

Induction of Differentiation by Pyruvate and DMEM in the Human Retinal Pigment Epithelium Cell Line ARPE-19

Neural Progenitor Cells Differentiate Into A Glial Lineage After Intravitreal And Subretinal Transplantation In A Degenerating Retinal Environment

Patterns Of Light-mediated C-fos Activity In The Medial Visual Cortex Of Mice Lacking Both Rods And Cones

Population Of Melanopsin-expressing Retinal Ganglion Cells In Aging Wildtype And Rodless/coneless Mice: A Detailed Quantitative And Topographical Analysis

Retinal Markers In The Developing Human Fetal Retinal Pigment Epithelium

Changes in Extracellular Matrix Components of ARPE-19 Cells by Fenretinide

Real-Time In Vivo Imaging of Retinal Cell Apoptosis after Laser Exposure

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