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Meeting Abstract (7)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (8)
Translational Vision Science & Technology (1)

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ARVO Annual Meeting Abstract (7)
Methods (1)
Retina (1)

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Eye Anatomy and Disorders (2)
Pharmacology (1)
Retina (1)
Translational Research (1)

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choroidal neovascularization (2)
mice (2)
animal model (1)
laser therapy (1)
lasers (1)
metformin (1)
retina (1)

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ARVO Annual Meeting Abstract June 2024

Western diets and gut dysbiosis are implicated in choroidal transcriptional dysregulation and neovascularization

Rohan Nishant Shah; Bingqing Xie; Hugo Barba; Jason Xiao; Jason Yang Zhang; Betty Theriault; Eugene B Chang; Dimitra Skondra

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4987.

Retina December 2023

Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis

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Jason Y. Zhang; Jason Xiao; Bingqing Xie; Hugo Barba; Michael Boachie-Mensah; Rohan N. Shah; Urooba Nadeem; Melanie Spedale; Nicholas Dylla; Huaiying Lin; Ashley M. Sidebottom; Mark D'Souza; Betty Theriault; Dinanath Sulakhe; Eugene B. Chang; Dimitra Skondra
TAGS: choroidal neovascularization, metformin, retina, mice
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):21. https://doi.org/10.1167/iovs.64.15.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Effects of Oral Metformin on Choroidal Neovascularization, RPE/Choroidal Transcriptome, and Gut Microbiota

Jason Yang Zhang; Jason Xiao; Bingqing Xie; Hugo Barba; Michael Boachie-Mensah; Urooba Nadeem; Melanie Spedale; Nicholas Dylla; Huaiying Lin; Mark D'Souza; Betty Theriault; Dinanath Sulakhe; Eugene B Chang; Dimitra Skondra

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2825.

ARVO Annual Meeting Abstract June 2023

Gut Microbiome Mediates Metformin’s Effects on Choroidal Neovascularization

Hugo Barba; Jason Yang Zhang; Jason Xiao; Bingqing Xie; Michael Boachie-Mensah; Urooba Nadeem; Melanie Spedale; Huaiying Lin; Mark D’Souza; Betty Theriault; Dinanath Sulakhe; Eugene B Chang; Dimitra Skondra

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3242.

ARVO Annual Meeting Abstract June 2023

Oral Metformin Reduces Choroidal Neoangiogenesis and Alters Microbiota-Derived Fecal Metabolites

Jason Xiao; Jason Yang Zhang; Bingqing Xie; Hugo Barba; Michael Boachie-Mensah; Urooba Nadeem; Melanie Spedale; Nicholas Dylla; Huaiying Lin; Ashley Sidebottom; Mark D’Souza; Betty Theriault; Dinanath Sulakhe; Eugene B Chang; Dimitra Skondra

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3021.

ARVO Annual Meeting Abstract June 2022

High-fat diet modulates the retinal pigment epithelium and choroid transcriptome in the absence of gut microbiota

Jason Xiao; Bingqing Xie; David Dao; Asadolah Movahedan; Mark D'Souza; Hugo Adrian Barba; Betty Theriault; Melanie Spedale; Eugene Chang; Dinanath Sulakhe; Dimitra Skondra

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):282 – F0327.

ARVO Annual Meeting Abstract June 2022

Germ-Free Laser-Induced Murine Model Shows The Effect Of The Microbial Organ On Choroidal Neovascularization.

Hugo Adrian Barba; Melanie Spedale; Jason Zhang; Asadolah Movahedan; Urooba Nadeem; Nini Deng; Eugene Chang; Betty Theriault; Dimitra Skondra

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):959 – A0428.

Methods August 2021

Gnotobiotic Operations and Assembly for Development of Germ-Free Animal Model of Laser-Induced Choroidal Neovascularization

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Asadolah Movahedan; Hugo Barba; Melanie Spedale; Nini Deng; Donna Arvans; Urooba Nadeem; Vanessa Leone; Eugene B. Chang; Betty Theriault; Dimitra Skondra
TAGS: animal model, choroidal neovascularization, lasers, mice, laser therapy
Trans. Vis. Sci. Tech.. 2021; 10(9):14. https://doi.org/10.1167/tvst.10.9.14

ARVO Annual Meeting Abstract July 2019

Gnotobiotic Animal Model of Laser-Induced Choroidal Neovascularization in Germ-Free Mice

Dimitra Skondra MD,PhD; Asadolah Movahedan; Melanie Spedale; Nini Deng; Vanessa Leone; Eugene Chang; Betty Theriault

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3273.

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Online ISSN: 2164-2591

Investigative Ophthalmology & Visual Science
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