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Letters to the Editor March 2024

Concerns About a Dog Model of Dry Eye Disease

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Ron Ofri; Nicholas J. Millichamp; Charlotte Keller; Gillian J. McLellan; András M. Komáromy; David Morton; Màrian Matas; Tammy M. Michau; Sarah Coall; Jane Sansom; Brian C Leonard
TAGS: dog, domestic, dry eye syndromes
Trans. Vis. Sci. Tech.. 2024; 13(3):28. https://doi.org/10.1167/tvst.13.3.28

Retina November 2023

Safety and Efficacy of Adeno-Associated Viral Gene Therapy in Patients With Retinal Degeneration: A Systematic Review and Meta-Analysis

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Mohamad Sobh; Pamela S. Lagali; Maryam Ghiasi; Joshua Montroy; Michael Dollin; Bernard Hurley; Brian C. Leonard; Ioannis Dimopoulos; Mackenzie Lafreniere; Dean A. Fergusson; Manoj M. Lalu; Catherine Tsilfidis

Trans. Vis. Sci. Tech.. 2023; 12(11):24. https://doi.org/10.1167/tvst.12.11.24

Includes: Supplemental Content

Cornea April 2023

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

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Brian C. Leonard; Sangwan Park; Soohyun Kim; Laura J. Young; Iman Jalilian; Krista Cosert; Xunzhi Zhang; Jessica M. Skeie; Hanna Shevalye; Nayeli Echeverria; Vanessa Rozo; Xin Gong; Chao Xing; Christopher J. Murphy; Mark A. Greiner; V. Vinod Mootha; Vijay Krishna Raghunathan; Sara M. Thomasy
TAGS: cornea, endothelium, hereditary corneal dystrophy, mice, signs and symptoms, proteins
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):22. https://doi.org/10.1167/iovs.64.4.22

Includes: Supplemental Content

Cornea & External Disease September 2022

Normal Corneal Thickness and Endothelial Cell Density in Rhesus Macaques ( Macaca mulatta )

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M. Isabel Casanova; Laura J. Young; Sangwan Park; Soohyun Kim; Karolina Roszak; Brian C. Leonard; Andrew Blandino; Monica J. Motta; Glenn Yiu; Jennifer Y. Li; Ala Moshiri; Sara M. Thomasy
TAGS: cornea, endothelial cells, macaca mulatta, body weight
Trans. Vis. Sci. Tech.. 2022; 11(9):23. https://doi.org/10.1167/tvst.11.9.23

Cornea & External Disease September 2022

Topical Ripasudil for the Treatment of Primary Corneal Endothelial Degeneration in Dogs

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Sarah R. Michalak; Soohyun Kim; Sangwan Park; M. Isabel Casanova; Morgan A. W. Bowman; Michelle Ferneding; Brian C. Leonard; Kathryn L. Good; Jennifer Y. Li; Sara M. Thomasy
TAGS: cornea, dog, domestic, endothelium, eye, tissue degeneration, corneal edema, edema
Trans. Vis. Sci. Tech.. 2022; 11(9):2. https://doi.org/10.1167/tvst.11.9.2

ARVO Annual Meeting Abstract June 2022

Antimicrobial Peptide Expression of the Equine Ocular Surface and Amniotic Membrane

Erin A Hisey; Bianca Da Costa Martins; Christopher J Murphy; Sara M Thomasy; Brian C Leonard

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):889 – A0253.

ARVO Annual Meeting Abstract June 2022

Role of TgWIP on the migration of Toxoplasma gondii into the eye

Vanessa Rozo; Sangwan Park; Lamba O Sangare; David Arranz Solis; Sara M Thomasy; Jeroen Saeij; Brian C Leonard

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1681 – A0511.

ARVO Annual Meeting Abstract June 2022

Effects of long-term application of topical ROCK inhibitor on corneal endothelium and Descemet’s membrane of TAZ deficient mice

Sara M Thomasy; Sangwan Park; Krista Cosert; Michelle Mccorkell; Nayeli Echeverria; Sophie M Le; Christopher J Murphy; Vijaykrishna Raghunathan; Brian C Leonard

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2280.

ARVO Annual Meeting Abstract June 2022

Topical netarsudil for the treatment of canine corneal endothelial degeneration

M Isabel Casanova; Nayeli Echeverria; Morgan AW Bowman; Melaney Annette Mayes; Kathryn L Good; Brian C Leonard; Christopher J Murphy; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2748 – A0237.

ARVO Annual Meeting Abstract June 2022

Single cell-RNA sequencing analysis of corneal endothelial cells in TAZ deficient mice

Sangwan Park; Brian C Leonard; Michelle Ferneding; Sophie M Le; Monica Ardon; Christopher J Murphy; Vijaykrishna Raghunathan; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2746 – A0235.

ARVO Annual Meeting Abstract June 2022

Topical application of a novel Harderian-derived nonpolar lipid prolongs tear film break up time in normal Beagle dogs

Brian C Leonard; Sangwan Park; Daniel M Albert; Charles A. O’Neill; Thomas R. Gadek; Atul N. Parikh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3986 – A0266.

Perspective February 2022

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

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Colleen M. McDowell; Krishnakumar Kizhatil; Michael H. Elliott; Darryl R. Overby; Joseph van Batenburg-Sherwood; J. Cameron Millar; Markus H. Kuehn; Gulab Zode; Ted S. Acott; Michael G. Anderson; Sanjoy K. Bhattacharya; Jacques A. Bertrand; Terete Borras; Diane E. Bovenkamp; Lin Cheng; John Danias; Michael Lucio De Ieso; Yiqin Du; Jennifer A. Faralli; Rudolf Fuchshofer; Preethi S. Ganapathy; Haiyan Gong; Samuel Herberg; Humberto Hernandez; Peter Humphries; Simon W. M. John; Paul L. Kaufman; Kate E. Keller; Mary J. Kelley; Ruth A. Kelly; David Krizaj; Ajay Kumar; Brian C. Leonard; Raquel L. Lieberman; Paloma Liton; Yutao Liu; Katy C. Liu; Navita N. Lopez; Weiming Mao; Timur Mavlyutov; Fiona McDonnell; Gillian J. McLellan; Philip Mzyk; Andrews Nartey; Louis R. Pasquale; Gaurang C. Patel; Padmanabhan P. Pattabiraman; Donna M. Peters; Vijaykrishna Raghunathan; Ponugoti Vasantha Rao; Naga Rayana; Urmimala Raychaudhuri; Ester Reina-Torres; Ruiyi Ren; Douglas Rhee; Uttio Roy Chowdhury; John R. Samples; E. Griffen Samples; Najam Sharif; Joel S. Schuman; Val C. Sheffield; Cooper H. Stevenson; Avinash Soundararajan; Preeti Subramanian; Chenna Kesavulu Sugali; Yang Sun; Carol B. Toris; Karen Y. Torrejon; Amir Vahabikashi; Janice A. Vranka; Ting Wang; Colin E. Willoughby; Chen Xin; Hongmin Yun; Hao F. Zhang; Michael P. Fautsch; Ernst R. Tamm; Abbot F. Clark; C. Ross Ethier; W. Daniel Stamer
TAGS: eye, mice, ocular hypertension, intraocular pressure, perfusion
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):12. https://doi.org/10.1167/iovs.63.2.12

Articles October 2021

Metal Oxide Engineered Nanomaterials Modulate Rabbit Corneal Fibroblast to Myofibroblast Transformation

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Atsuhiko Fukuto; Soohyun Kim; Jennifer Kang; Brooke L. Gates; Maggie W. Chang; Kent E. Pinkerton; Laura S. Van Winkle; Yoshiaki Kiuchi; Christopher J. Murphy; Brian C. Leonard; Sara M. Thomasy
TAGS: cornea, fibroblasts, metals, myofibroblasts, nanostructures, oryctolagus cuniculus, oxides, proteins, cell survival, rna, messenger
Trans. Vis. Sci. Tech.. 2021; 10(12):23. https://doi.org/10.1167/tvst.10.12.23

Includes: Supplemental Content

Anatomy and Pathology/Oncology May 2018

A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice

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Bret A. Moore; Michel J. Roux; Lionel Sebbag; Ann Cooper; Sydney G. Edwards; Brian C. Leonard; Denise M. Imai; Stephen Griffey; Lynette Bower; Dave Clary; K. C. Kent Lloyd; Yann Hérault; Sara M. Thomasy; Christopher J. Murphy; Ala Moshiri
TAGS: eye abnormalities, mice, mice, inbred c57bl, eye, population studies, cornea
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2252-2261. https://doi.org/10.1167/iovs.17-23513

Includes: Supplemental Content

Retina March 2017

Arap1 Deficiency Causes Photoreceptor Degeneration in Mice

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Ala Moshiri; Devin Humpal; Brian C. Leonard; Denise M. Imai; Addy Tham; Lynette Bower; Dave Clary; Thomas M. Glaser; K. C. Kent Lloyd; Christopher J. Murphy
TAGS: mice, photoreceptors, tissue degeneration, retina, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1709-1718. https://doi.org/10.1167/iovs.16-20062

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

X-Linked Inhibitor of Apoptosis Gene Therapy Protects Retinal Structure in a Feline Model of Retinal Detachment

Sarah J Wassmer; Brian C Leonard; Stuart G Coupland; John Hamilton; Adam N Baker; Lijun Fang; Catherine Tsilfidis

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4041.

Cornea December 2015

Effect of Stratification on Surface Properties of Corneal Epithelial Cells

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Bernardo Yáñez-Soto; Brian C. Leonard; Vijay Krishna Raghunathan; Nicholas L. Abbott; Christopher J. Murphy
TAGS: cell culture techniques, corneal epithelial cells, corneal epithelium, dry eye syndromes, engineering, hysteresis, mucins, stratification, surface properties, heterogeneity
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8340-8348. https://doi.org/10.1167/iovs.15-17468

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Interfacial properties of corneal epithelial cells at different degrees of differentiation

Bernardo Yanez; Brian C Leonard; VijayKrishna Raghunathan; Nicholas L Abbott; Christopher J Murphy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1482.

ARVO Annual Meeting Abstract April 2014

Species-specific variation in mucin expression from corneal epithelium

Brian C Leonard; Bernardo Yanez; VijayKrishna Raghunathan; Nicholas L Abbott; Christopher J Murphy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1500.

ARVO Annual Meeting Abstract April 2014

Detecting Early Signs of Hydroxychloroquine and Chloroquine Retinopathy: A Meta-analysis Evaluating Multifocal Electroretinogram as a Screening Test under the 2011 Revised American Academy of Ophthalmology Guidelines

Sina Ahmadi Pirshahid; Chloe C Gottlieb; Stuart G Coupland; Adrian Tsang; Brian C Leonard; Bernard Hurley

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5116.

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Concerns About a Dog Model of Dry Eye Disease

Safety and Efficacy of Adeno-Associated Viral Gene Therapy in Patients With Retinal Degeneration: A Systematic Review and Meta-Analysis

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

Normal Corneal Thickness and Endothelial Cell Density in Rhesus Macaques ( Macaca mulatta )

Topical Ripasudil for the Treatment of Primary Corneal Endothelial Degeneration in Dogs

Antimicrobial Peptide Expression of the Equine Ocular Surface and Amniotic Membrane

Role of TgWIP on the migration of Toxoplasma gondii into the eye

Effects of long-term application of topical ROCK inhibitor on corneal endothelium and Descemet’s membrane of TAZ deficient mice

Topical netarsudil for the treatment of canine corneal endothelial degeneration

Single cell-RNA sequencing analysis of corneal endothelial cells in TAZ deficient mice

Topical application of a novel Harderian-derived nonpolar lipid prolongs tear film break up time in normal Beagle dogs

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

Metal Oxide Engineered Nanomaterials Modulate Rabbit Corneal Fibroblast to Myofibroblast Transformation

A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice

Arap1 Deficiency Causes Photoreceptor Degeneration in Mice

X-Linked Inhibitor of Apoptosis Gene Therapy Protects Retinal Structure in a Feline Model of Retinal Detachment

Effect of Stratification on Surface Properties of Corneal Epithelial Cells

Interfacial properties of corneal epithelial cells at different degrees of differentiation

Species-specific variation in mucin expression from corneal epithelium

Detecting Early Signs of Hydroxychloroquine and Chloroquine Retinopathy: A Meta-analysis Evaluating Multifocal Electroretinogram as a Screening Test under the 2011 Revised American Academy of Ophthalmology Guidelines

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