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Glaucoma January 2025

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

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Daniel Kim; Raymond Fang; Pengpeng Zhang; Zihang Yan; Cheng Sun; Guorong Li; Christa Montgomery; Simon W. M. John; W. Daniel Stamer; Hao F. Zhang; C. Ross Ethier
TAGS: anterior chamber of eye, aqueous humor, diagnostic imaging, eye, mice, vaccine information sheets, volume, x-ray microtomography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):18. https://doi.org/10.1167/iovs.66.1.18

Includes: Supplemental Content

Perspective December 2024

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

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Ted S. Acott; Michael P. Fautsch; Weiming Mao; C. Ross Ethier; Alex S. Huang; Mary J. Kelley; Mini Aga; Sanjoy K. Bhattacharya; Terete Borras; Diane Bovenkamp; Uttio Roy Chowdhury; Abbot F. Clark; Mohammed I. Dibas; Yiqin Du; Michael H. Elliott; Jennifer A. Faralli; Haiyan Gong; Samuel Herberg; Murray A. Johnstone; Paul L. Kaufman; Kate E. Keller; Ruth A. Kelly; David Krizaj; Markus H. Kuehn; Hoi Lam Li; Raquel Lieberman; Shan C. Lin; Yutao Liu; Fiona S. McDonnell; Colleen M. McDowell; Gillian J. McLellan; Philip Mzyk; Kayarat Saidas Nair; Darryl R. Overby; Donna M. Peters; VijayKrishna Raghunathan; Ponugoti Vasantha Rao; Gavin W. Roddy; Najam A. Sharif; Myoung Sup Shim; Yang Sun; Benjamin R. Thomson; Carol B. Toris; Colin E. Willoughby; Hao F. Zhang; Thomas F. Freddo; Rudolf Fuchshofer; Kamisha R. Hill; Alireza Karimi; Krishnakumar Kizhatil; Casey C. Kopcyznski; Paloma Liton; Gaurang Patel; Michael Peng; Padmanabhan P. Pattabiraman; Ganesh Prasanna; Ester Reina-Torres; E. Griffen Samples; John R. Samples; Cynthia L. Steel; Clemens A. Strohmaier; Preeti Subramanian; Chenna Kesavulu Sugali; Joseph van Batenburg-Sherwood; Cydney Wong; Hannah Youngblood; Gulab S. Zode; Elizabeth White; W. Daniel Stamer
TAGS: body tissue, eye, fluid flow, intraocular pressure, perfusion, regulation, organ culture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):32. https://doi.org/10.1167/iovs.65.14.32

Glaucoma October 2024

IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

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Yooree G. Chung; Shan Fan; Vikas Gulati; Hoi-Lam Li; Haiyan Gong; Carol B. Toris; Mark R. Prausnitz; C. Ross Ethier
TAGS: hydrogel, injections, intraocular pressure, eye, hypertension
Trans. Vis. Sci. Tech.. 2024; 13(10):14. https://doi.org/10.1167/tvst.13.10.14

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Magnetically-steered Human Mesenchymal Stem Cells Lower Intraocular Pressure (IOP) for 9 Months in Mice

C Ross Ethier; M. Reza Bahrani Fard; Jessica T. Chan; A. Thomas Read; Guorong Li; Lin Cheng; Anamik Jhunjhunwala; Babak N. Safa; Seyed Mohammad Siadat; Hans E Grossniklaus; Stanislav Y. Emelianov; W Daniel Stamer; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6460.

ARVO Annual Meeting Abstract June 2024

Hydrogel Expansion of the Suprachoroidal Space Lowers IOP by Increasing Unconventional Outflow

Yooree Grace Chung; Mark R Prausnitz; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3501.

ARVO Annual Meeting Abstract June 2024

Investigating the Dynamic Behavior of Murine Pectinate Ligaments in Response to Intraocular Pressure Changes

babak safa; Nina Sara Fraticelli-Guzman; W Daniel Stamer; Andrew J. Feola; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2490.

ARVO Annual Meeting Abstract June 2024

Extracellular Calcium Entry via Mechanosensitive Ion Channels is Necessary for Transcellular Pore Formation in Schlemm’s Canal Endothelial Cells

Jacques A Bertrand; C Ross Ethier; W Daniel Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5155.

ARVO Annual Meeting Abstract June 2024

TRPV4 integrates matrix mechanosensing with Ca 2+ signaling to modulate Schlemm’s canal cell mechanobiology

Haiyan Li; Seyed Mohammad Siadat; Kristin Marie Perkumas; Jacques A Bertrand; Darryl R Overby; Todd Sulchek; Dan W Stamer; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4264.

ARVO Annual Meeting Abstract June 2024

Mouse Trabecular Meshwork Stiffness in High and Low Flow Regions

Cydney A Wong; A. Thomas Read; Guorong Li; Amia Loveless; Todd Sulchek; W Daniel Stamer; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2489.

ARVO Annual Meeting Abstract June 2024

The Nitric Oxide Concentration within Schlemm’s Canal Depends on IOP

Darryl R Overby; W Daniel Stamer; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5162.

ARVO Annual Meeting Abstract June 2024

Effects of light exposure and dopamine on all-trans retinoic acid in the murine eye

Sarah Talwar; Reece Mazade; Jianshi Yu; Nageswara Pilli; Maureen A. Kane; C Ross Ethier; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1166.

ARVO Annual Meeting Abstract June 2024

Dosage effects of oral all-trans retinoic acid on murine ocular parameters

Melissa Bentley-Ford; Linjiang Lou; Prasan K. Chari; Maureen A. Kane; C Ross Ethier; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1161.

ARVO Annual Meeting Abstract June 2024

Assessing the Stiffness of Ocular Tissues in Rodents Using Atomic Force Microscopy

Nina Sara Fraticelli-Guzman; Cydney A Wong; Todd Sulchek; A. Thomas Read; C Ross Ethier; Andrew J. Feola

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2502.

ARVO Annual Meeting Abstract June 2024

The mechanobiology of glaucoma

C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2123.

Physiology and Pharmacology June 2024

The Factors Affecting the Stability of IOP Homeostasis

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Darryl R. Overby; C. Ross Ethier; Changxu Miao; Ruth A. Kelly; Ester Reina-Torres; W. Daniel Stamer
TAGS: fluid flow, homeostasis, intraocular pressure, perfusion, perturbations, shear stress
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):4. https://doi.org/10.1167/iovs.65.6.4

Includes: Supplemental Content

Retina April 2024

Drug Distribution After Intravitreal Injection: A Mathematical Model

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Alessia Ruffini; Alessia Casalucci; Caterina Cara; C. Ross Ethier; Rodolfo Repetto
TAGS: drug distribution, eye, injections, intravitreal injections, mathematical model, vitreous body, intraocular pressure, fluid flow, biological transport
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):9. https://doi.org/10.1167/iovs.65.4.9

ARVO Annual Meeting Abstract June 2023

Aging modifies conventional outflow tissue morphology, response to pressure challenge and proteomic signature of C57BL/6 mice

Guorong Li; Andrea Wilson; Michael Lucio De Ieso; Nikolai P Skiba; Sina Farsiu; C Ross Ethier; W Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4740.

ARVO Annual Meeting Abstract June 2023

Development of a Schlemm’s Canal “Inner Wall on a Chip” for High Content Screening

Seyed Mohammad Siadat; Jacques A Bertrand; Darryl R Overby; W Daniel Stamer; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):50.

ARVO Annual Meeting Abstract June 2023

Effects of age and ovariectomy on ECM and TGF-b signaling gene sets in Brown Norway rat scleras

Cydney Wong; Gabriela Sánchez-Rodríguez; C Ross Ethier; Levi Wood; Andrew J. Feola

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):404.

ARVO Annual Meeting Abstract June 2023

Hydrogel Expansion of the Suprachoroidal Space Lowers IOP in Rabbit and Monkey Eyes

Yooree Grace Chung; Carol B Toris; Vikas Gulati; Shan Fan; Mark Prausnitz; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3475.

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In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

Magnetically-steered Human Mesenchymal Stem Cells Lower Intraocular Pressure (IOP) for 9 Months in Mice

Hydrogel Expansion of the Suprachoroidal Space Lowers IOP by Increasing Unconventional Outflow

Investigating the Dynamic Behavior of Murine Pectinate Ligaments in Response to Intraocular Pressure Changes

Extracellular Calcium Entry via Mechanosensitive Ion Channels is Necessary for Transcellular Pore Formation in Schlemm’s Canal Endothelial Cells

TRPV4 integrates matrix mechanosensing with Ca 2+ signaling to modulate Schlemm’s canal cell mechanobiology

Mouse Trabecular Meshwork Stiffness in High and Low Flow Regions

The Nitric Oxide Concentration within Schlemm’s Canal Depends on IOP

Effects of light exposure and dopamine on all-trans retinoic acid in the murine eye

Dosage effects of oral all-trans retinoic acid on murine ocular parameters

Assessing the Stiffness of Ocular Tissues in Rodents Using Atomic Force Microscopy

The mechanobiology of glaucoma

The Factors Affecting the Stability of IOP Homeostasis

Drug Distribution After Intravitreal Injection: A Mathematical Model

Aging modifies conventional outflow tissue morphology, response to pressure challenge and proteomic signature of C57BL/6 mice

Development of a Schlemm’s Canal “Inner Wall on a Chip” for High Content Screening

Effects of age and ovariectomy on ECM and TGF-b signaling gene sets in Brown Norway rat scleras

Hydrogel Expansion of the Suprachoroidal Space Lowers IOP in Rabbit and Monkey Eyes

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