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ARVO Annual Meeting Abstract June 2024

Developing Cathepsin L inhibitors as novel treatments for recurrent ocular toxoplasmosis

Eric Weh; Pariyamon Thaprawat; Tracey L Schultz; Amanda Flora; Shubha Subramanya; Heather Hager; Martin Clasby; Vern B Carruthers; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5607.

ARVO Annual Meeting Abstract June 2023

Metabolic reprogramming of myeloid cells with small molecule PKM2 activator MCTI-566 in the rd10 mouse

Warren Wang Pan; Eric Weh; Roshini Fernando; Sraboni Chaudhury; Shubha Subramanya; Nick Miller; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4880.

ARVO Annual Meeting Abstract June 2023

Attitudes towards telemedicine for screening of retinopathy of prematurity amongst NICU directors

Emily Cole; Emily Ann Eton; Cagri G Besirli; Thomas J Wubben; Yannis Mantas Paulus; Robison Vernon Paul Chan; J. Peter Campbell; Chris A. Andrews; David C Musch; Rebecca Vartanian

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4932.

ARVO Annual Meeting Abstract June 2023

Retinal metabolic and immunological changes in the TSC1 photoreceptor knockout mouse model of AMD

Eric Weh; Roshini Fernando; Moloy Goswami; Sraboni Chaudhury; Shubha Subramanya; Yousef Abdeh; Heather Hager; Anthony Andren; Costas Lyssiotis; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5088.

ARVO Annual Meeting Abstract June 2022

Flow cytometry methods to detect markers of outer retinal stress and cell death in a model of acute nutrient stress

Shubha Subramaya; Roshini Fernando; Moloy Goswami; Eric Weh; HEATHER HAGER; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):792 – F0351.

ARVO Annual Meeting Abstract June 2022

Novel PKM2 activators for photoreceptor neuroprotection: identifying potential clinical candidates

Sraboni Chaudhury; JASON RECH; BRENNAN WATCH; Eric Weh; HEATHER HAGER; Thomas J Wubben; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):670 – F0124.

ARVO Annual Meeting Abstract June 2022

Small molecule PKM2 activators in the treatment of rd10 photoreceptor degeneration

Warren Pan; Eric Weh; Roshini Fernando; Sraboni Chaudhury; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1779 – F0328.

ARVO Annual Meeting Abstract June 2022

Promoting PKM2 tetramerization to treat RPE epithelial-to-mesenchymal transition in proliferative vitreoretinopathy

Vikram Sharma; Moloy Goswami; Qitao Zhang; Sraboni Chaudhury; Katie Li; Hima Bindu Durumulta; Anthony Andren; Costas A Lyssiotis; Cagri G Besirli; Jason Matthew Lewis Miller; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3051 – F0422.

ARVO Annual Meeting Abstract June 2022

Trends in retinopathy of prematurity training and future practice intentions among retina and pediatric ophthalmology fellows

Emily Eton; Benjamin Young; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4173 – F0233.

ARVO Annual Meeting Abstract June 2022

Classification and growth rate of retinal atrophy after voretigene neparvovec-rzyl for RPE65-mediated retinal dystrophy

Nikhil Bommakanti; Benjamin Young; Robert Sisk; Audina M. Berrocal; Jacque L Duncan; Benjamin Bakall; Marc Mathias; Aaron Nagiel; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):456.

ARVO Annual Meeting Abstract June 2021

Modulation of pyruvate kinase M2 activity as a therapy in a primary RPE cell culture model of proliferative vitreoretinopathy

Katie Xiaoou Li; Moloy T. Goswami; Qitao Zhang; Hima Bindu Durumutla; Sraboni Chaudhury; Cagri G Besirli; Jason Miller; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2213.

ARVO Annual Meeting Abstract June 2021

HK2 and PKM2 deletion leads to outer segment shortening and photoreceptor degeneration

Eric Weh; Katie Xiaoou Li; Heather Hager; Sarah Sheskey; Thomas J Wubben; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2985.

ARVO Annual Meeting Abstract June 2021

Quantitative Analysis of VEGF in Infant Tears as a Biomarker for ROP

Omar Moinuddin; Jessie Magnani; Sanjana Sathrasala; Mercy Pawar; Rebecca Vartanian; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3257.

ARVO Annual Meeting Abstract June 2021

Glutaminase deficiency disrupts the bioenergetic and antioxidant fidelity of photoreceptors to induce rapid degeneration

Moloy Goswami; Eric Weh; Hima Bindu Durmutla; Heather Hager; Sraboni Chaudhury; costas lyssiotis; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3075.

ARVO Annual Meeting Abstract June 2021

Perifoveal Chorioretinal Atrophy Following Subretinal Injection of Voretigene Neparvovec-rzyl for RPE65-mediated Leber Congenital Amaurosis

William S Gange; Robert A Sisk; Cagri G Besirli; Thomas C Lee; Mark Borchert; Jesse Sengillo; Carlos Mendoza; Audina M Berrocal; Aaron Nagiel

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3292.

ARVO Annual Meeting Abstract June 2020

Association of metformin and development of dry age-related macular degeneration in a U.S. insurance claims database

Emily Ann Eton; Thomas J Wubben; Cagri G Besirli; Peiying Hua; Brendan McGeehan; Brian L VanderBeek

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2993.

ARVO Annual Meeting Abstract June 2020

Development of novel pyruvate kinase muscle isoform 2 (PKM2) activators for photoreceptor neuroprotection

Thomas J Wubben; Jason C Rech; Mercy D Pawar; Eric Weh; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4938.

Review June 2020

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

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Debra A. Thompson; Alessandro Iannaccone; Robin R. Ali; Vadim Y. Arshavsky; Isabelle Audo; James W. B. Bainbridge; Cagri G. Besirli; David G. Birch; Kari E. Branham; Artur V. Cideciyan; Steven P. Daiger; Deniz Dalkara; Jacque L. Duncan; Abigail T. Fahim; John G. Flannery; Roberto Gattegna; John R. Heckenlively; Elise Heon; K. Thiran Jayasundera; Naheed W. Khan; Henry Klassen; Bart P. Leroy; Robert S. Molday; David C. Musch; Mark E. Pennesi; Simon M. Petersen-Jones; Eric A. Pierce; Rajesh C. Rao; Thomas A. Reh; Jose A. Sahel; Dror Sharon; Paul A. Sieving; Enrica Strettoi; Paul Yang; David N. Zacks; The Monaciano Consortium
TAGS: outcome measures, retinal diseases, surrogate endpoints, genetics, vision, natural history, ethics, gene therapy
Trans. Vis. Sci. Tech.. 2020; 9(7):2. https://doi.org/10.1167/tvst.9.7.2

Articles September 2019

Magnetic Hyperthermia in Y79 Retinoblastoma and ARPE-19 Retinal Epithelial Cells: Tumor Selective Apoptotic Activity of Iron Oxide Nanoparticle

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Hakan Demirci; Naziha Slimani; Mercy Pawar; Ronald E. Kumon; Prem Vaishnava; Cagri G. Besirli
TAGS: ferumoxytol, hyperthermia, nanoparticles, neoplasms, retinoblastoma, epithelial cells
Trans. Vis. Sci. Tech.. 2019; 8(5):18. https://doi.org/10.1167/tvst.8.5.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Protective role of mesencephalic astrocyte-derived neurotrophic factor (MANF) in photoreceptor death

Mercy D Pawar; Taichi Suzuki; Kevin Toolan; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6606.

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Developing Cathepsin L inhibitors as novel treatments for recurrent ocular toxoplasmosis

Metabolic reprogramming of myeloid cells with small molecule PKM2 activator MCTI-566 in the rd10 mouse

Attitudes towards telemedicine for screening of retinopathy of prematurity amongst NICU directors

Retinal metabolic and immunological changes in the TSC1 photoreceptor knockout mouse model of AMD

Flow cytometry methods to detect markers of outer retinal stress and cell death in a model of acute nutrient stress

Novel PKM2 activators for photoreceptor neuroprotection: identifying potential clinical candidates

Small molecule PKM2 activators in the treatment of rd10 photoreceptor degeneration

Promoting PKM2 tetramerization to treat RPE epithelial-to-mesenchymal transition in proliferative vitreoretinopathy

Trends in retinopathy of prematurity training and future practice intentions among retina and pediatric ophthalmology fellows

Classification and growth rate of retinal atrophy after voretigene neparvovec-rzyl for RPE65-mediated retinal dystrophy

Modulation of pyruvate kinase M2 activity as a therapy in a primary RPE cell culture model of proliferative vitreoretinopathy

HK2 and PKM2 deletion leads to outer segment shortening and photoreceptor degeneration

Quantitative Analysis of VEGF in Infant Tears as a Biomarker for ROP

Glutaminase deficiency disrupts the bioenergetic and antioxidant fidelity of photoreceptors to induce rapid degeneration

Perifoveal Chorioretinal Atrophy Following Subretinal Injection of Voretigene Neparvovec-rzyl for RPE65-mediated Leber Congenital Amaurosis

Association of metformin and development of dry age-related macular degeneration in a U.S. insurance claims database

Development of novel pyruvate kinase muscle isoform 2 (PKM2) activators for photoreceptor neuroprotection

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

Magnetic Hyperthermia in Y79 Retinoblastoma and ARPE-19 Retinal Epithelial Cells: Tumor Selective Apoptotic Activity of Iron Oxide Nanoparticle

Protective role of mesencephalic astrocyte-derived neurotrophic factor (MANF) in photoreceptor death

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