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ARVO Annual Meeting Abstract June 2023

Minimally invasive keratoprosthesis (mi-KPro) for vision restoration after severe chemical injury.

Jyoti Sharma; Thomas H Dohlman; Chengxin Zhou; Peter York; Fengyang Lei; Jie Liu; Robert Woods; Claes Dohlman; James Chodosh; Roberto Pineda; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5136.

ARVO Annual Meeting Abstract June 2022

Compensatory expression of Crystallin γS in retinal microglia neutralizes endotoxin-induced neuroinflammation

Fengyang Lei; Naiwen Cui; Chengxin Zhou; Yamei Cai; Nikolaos Efstathiou; James Chodosh; Demetrios G. Vavvas; Huidan Zhang; David Weitz; Graeme J. Wistow; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3517.

ARVO Annual Meeting Abstract June 2021

Manipulation of Gut Microbiota Affects Diet- and Age-Related Retinal Degeneration

Sheldon Rowan; Sarah G Francisco; Chia-Fang Tsai; Kathryn Barger; Donald Smith; Chengxin Zhou; Eleftherios I Paschalis; Allen Taylor; Kelsey M Smith

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2238.

ARVO Annual Meeting Abstract June 2021

Single-cell RNA-seq reveals a dynamic shift of engrafted peripheral macrophages in the CNS towards a microglia signature.

Fengyang Lei; Naiwen Cui; Chengxin Zhou; Yamei Cai; Claes H Dohlman; James Chodosh; Demetrios G. Vavvas; Huidan Zhang; David A Weitz; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):918.

ARVO Annual Meeting Abstract June 2021

Anti-inflammatory medication after corneal trauma or surgery to prevent subsequent late glaucoma.

Eleftherios I Paschalis; Chengxin Zhou; Fengyang Lei; Sarah Kim; Demetrios G. Vavvas; James Chodosh; Arto Urtti; George Papaliodis; Claes H Dohlman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):891.

ARVO Annual Meeting Abstract June 2021

Safety and efficacy of a novel injectable anti-TNF-α/anti-VEGF drug delivery system for corneal and retinal protection after injury.

Chengxin Zhou; Pui-Chuen Hui; Natalie Wolkow; Claes H Dohlman; Demetrios G. Vavvas; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1206.

Articles July 2020

Microporous Drug Delivery System for Sustained Anti-VEGF Delivery to the Eye

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Chengxin Zhou; Arushi Singh; Grace Qian; Natalie Wolkow; Claes H. Dohlman; Demetrios G. Vavvas; James Chodosh; Eleftherios I. Paschalis
TAGS: anti-vascular endothelial growth factor therapy, cornea, eye, drug delivery systems
Trans. Vis. Sci. Tech.. 2020; 9(8):5. https://doi.org/10.1167/tvst.9.8.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Inflammatory damage to the limbal stem cells after acute ocular injury: Protection with TNF-α inhibition

Chengxin Zhou; Fengyang Lei; Bruce Ksander; Claes H Dohlman; James Chodosh; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):371.

ARVO Annual Meeting Abstract July 2019

Peripheral monocyte are involved in permanent retinal neuroglia remodeling after injury.

Eleftherios I Paschalis; Fengyang Lei; Chengxin Zhou; Claes H Dohlman; Reza Dana; James Chodosh; Demetrios Vavvas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2799.

ARVO Annual Meeting Abstract July 2019

Retinal inflammation after penetrating corneal surgery: the role of TNF-α and IL-1β inhibition.

XIAONIAO CHEN; Fengyang Lei; Chengxin Zhou; Eleftherios I Paschalis; James Chodosh; Claes H Dohlman; Liqiang Wang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):893.

ARVO Annual Meeting Abstract July 2019

Permanent neuroglial remodeling after acute ocular injury

Fengyang Lei; Chengxin Zhou; Claes H Dohlman; Reza Dana; James Chodosh; Demetrios Vavvas; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3992.

ARVO Annual Meeting Abstract July 2018

Evaluation of a sustained drug delivery system for anti-VEGF antibody after alkali burns to the eye

Chengxin Zhou; Vassiliki Kapoulea; James Chodosh; Claes H Dohlman; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2579.

ARVO Annual Meeting Abstract July 2018

Anti-TNF-α treatment in skin burns

Vassiliki Kapoulea; Chengxin Zhou; Fengyang Lei; Natalie Wolkow; Lina Ma; Thaddeus P Dryja; James Chodosh; Claes H Dohlman; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2664.

ARVO Annual Meeting Abstract June 2017

Evaluation of intraocular pressure and inflammation after Boston K-Pro implantation in Rabbits.

Vassiliki Kapoulea; Elise Taniguchi; Yingqian Li; Chengxin Zhou; Fengyang Lei; James Chodosh; Dong Feng Chen; Claes H Dohlman; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2561.

ARVO Annual Meeting Abstract June 2017

Corneal alkali injury induces retinopathy via inflammation that is preventable with anti-TNF-α treatment

Fengyang Lei; Chengxin Zhou; Vassiliki Kapoulea; James Chodosh; Claes H Dohlman; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5730.

ARVO Annual Meeting Abstract June 2017

The Mechanism of Retinal Damage Following Ocular Surface Burn with Alkali

Chengxin Zhou; Fengyang Lei; Nathan Scott; Vassiliki Kapoulea; Marie-Claude Robert; James Chodosh; Claes H Dohlman; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5892.

Cornea January 2017

Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye

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Chengxin Zhou; Marie-Claude Robert; Vassiliki Kapoulea; Fengyang Lei; Anna M. Stagner; Frederick A. Jakobiec; Claes H. Dohlman; Eleftherios I. Paschalis
TAGS: alkalies, burns, cornea, eye, infliximab, tumor necrosis factors, subconjunctival route, retina, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):96-105. https://doi.org/10.1167/iovs.16-20339

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Evaluation of a therapeutic anti-TNF-α drug delivery system for ocular alkali burns

Chengxin Zhou; Marie-Claude Robert; Fengyang Lei; Vassiliki Kapoulea; James Chodosh; Claes H Dohlman; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1271.

ARVO Annual Meeting Abstract September 2016

Acute ocular surface injury causes prompt infiltration of circulating monocytes into the retina

Fengyang Lei; Chengxin Zhou; Vassiliki Kapoulea; James Chodosh; Claes H Dohlman; Eleftherios I Paschalis

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4492.

Cornea April 2016

The Role of Titanium Surface Microtopography on Adhesion, Proliferation, Transformation, and Matrix Deposition of Corneal Cells

PDF

Chengxin Zhou; Fengyang Lei; James Chodosh; Eleftherios I. Paschalis
TAGS: adhesions, cornea, titanium, collagen, fibroblasts, cytotoxicity
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1927-1938. https://doi.org/10.1167/iovs.15-18406

Includes: Supplemental Content

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Minimally invasive keratoprosthesis (mi-KPro) for vision restoration after severe chemical injury.

Compensatory expression of Crystallin γS in retinal microglia neutralizes endotoxin-induced neuroinflammation

Manipulation of Gut Microbiota Affects Diet- and Age-Related Retinal Degeneration

Single-cell RNA-seq reveals a dynamic shift of engrafted peripheral macrophages in the CNS towards a microglia signature.

Anti-inflammatory medication after corneal trauma or surgery to prevent subsequent late glaucoma.

Safety and efficacy of a novel injectable anti-TNF-α/anti-VEGF drug delivery system for corneal and retinal protection after injury.

Microporous Drug Delivery System for Sustained Anti-VEGF Delivery to the Eye

Inflammatory damage to the limbal stem cells after acute ocular injury: Protection with TNF-α inhibition

Peripheral monocyte are involved in permanent retinal neuroglia remodeling after injury.

Retinal inflammation after penetrating corneal surgery: the role of TNF-α and IL-1β inhibition.

Permanent neuroglial remodeling after acute ocular injury

Evaluation of a sustained drug delivery system for anti-VEGF antibody after alkali burns to the eye

Anti-TNF-α treatment in skin burns

Evaluation of intraocular pressure and inflammation after Boston K-Pro implantation in Rabbits.

Corneal alkali injury induces retinopathy via inflammation that is preventable with anti-TNF-α treatment

The Mechanism of Retinal Damage Following Ocular Surface Burn with Alkali

Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye

Evaluation of a therapeutic anti-TNF-α drug delivery system for ocular alkali burns

Acute ocular surface injury causes prompt infiltration of circulating monocytes into the retina

The Role of Titanium Surface Microtopography on Adhesion, Proliferation, Transformation, and Matrix Deposition of Corneal Cells

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