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ARVO Annual Meeting Abstract June 2024

A metabolome-wide analysis of Intraocular pressure suggests neuroinflammatory mechanisms as possible mechanisms involved in glaucoma

Pirro G Hysi; Ajda Pristavec; Anthony P Khawaja; Jospeh Bastasic; David A Mackey; Janey L Wiggs; Jamie E Craig; Louis R Pasquale; Christopher J Hammond; Marie-Hélène Roy-Gagnon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):997.

ARVO Annual Meeting Abstract June 2024

Are we amid a dry eye epidemic? - The increasing prevalence of dry eye disease in Europe

Morten S Magno; Leif Hynnekleiv; Christopher J Hammond; Tor Utheim; Jelle Vehof

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2855.

ARVO Annual Meeting Abstract June 2024

Exploring kinetics of the ganglion cell contribution to standard light-adapted flash electroretinograms by interocular comparison in patients with unilateral ganglion cell loss

Ahmed Ellabban; Harry Frederick Arbuthnott; Charlie Bosshard; Gordon Plant; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1534.

ARVO Annual Meeting Abstract June 2024

Enhanced deep metagenomic sequencing of ocular microbes using saponification with the Nanopore platform

Jeremy Mirza; Michael Tsun Lau; Graham R Wallace; Philip Ian Murray; Christopher J Hammond; Russell N Van Gelder; Saaeha Rauz; Liying Low

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3183.

ARVO Annual Meeting Abstract June 2024

Epigenetic modifiers and their interactions with genetic polymorphisms in Intraocular Pressure and glaucoma

Xiaofan Jiang; Omar Abdul Rahman Mahroo; Dorota Skowronska-Krawczyk; Christopher J Hammond; Chris G Bell; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4626.

ARVO Annual Meeting Abstract June 2024

Modelling the rod-driven electroretinogram a-wave elicited by strong flashes: insights from patients with selected post-phototransduction impairments

Omar Abdul Rahman Mahroo; Xiaofan Jiang; Shaun Leo; Pirro G Hysi; Thales A C De Guimarães; Anthony G Robson; Christopher J Hammond; Michel Michaelides; Andrew Webster; John Robson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5854.

ARVO Annual Meeting Abstract June 2024

Metabolome-wide analysis identifies two plasma metabolites associated with age-related macular degeneration

Ajda Pristavec; Zakariya Jarrar; Pirro G Hysi; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6513.

Retina February 2024

Temporal-to-Nasal Macular Ganglion Cell and Inner Plexiform Layer Ratios in a Large Adult Twin Cohort: Correlations With Age and Heritability

PDF

Zakariya A. Jarrar; Khaldoon O. Al-Nosairy; Xiaofan Jiang; Ali Lamin; Dominic Wong; Abdus S. Ansari; Katie M. Williams; Sobha Sivaprasad; Michael B. Hoffmann; Pirro G. Hysi; Christopher J. Hammond; Omar A. Mahroo
TAGS: adult, cohort studies, ganglia, nose, twins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):26. https://doi.org/10.1167/iovs.65.2.26

Clinical and Epidemiologic Research November 2023

Changes in Refractive Error During Young Adulthood: The Effects of Longitudinal Screen Time, Ocular Sun Exposure, and Genetic Predisposition

PDF

Samantha Sze-Yee Lee; Gareth Lingham; Carol A. Wang; Santiago Diaz Torres; Craig E. Pennell; Pirro G. Hysi; Christopher J. Hammond; Puya Gharahkhani; Rosie Clark; Jeremy A. Guggenheim; David A. Mackey
TAGS: adult, genetic predisposition to disease, myopia, refractive errors, screen time, sun exposure
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):28. https://doi.org/10.1167/iovs.64.14.28

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2023

Prevalence, Concordance, and Heritability of Vitreomacular Interface Abnormalities in a Twin Study

PDF

Zakariya A. Jarrar; Abdus Samad Ansari; Katie M. Williams; Dominic S. Wong; Pirro G. Hysi; Omar A. Mahroo; Christopher J. Hammond
TAGS: prevalence, spectral domain-optical coherence tomography, twin studies
Invest. Ophthalmol. Vis. Sci.. 2023; 64(10):9. https://doi.org/10.1167/iovs.64.10.9

Includes: Supplemental Content

Retina June 2023

An Analysis of the Effect of ABCA4 p.Asn1868Ile Genotypes on Retinal Structure in 26,558 Participants in the UK Biobank

PDF

Mark J. Simcoe; Gavin Arno; Pirro G. Hysi; Tony Ko; Michel Michaelides; Christopher J. Hammond; Praveen J. Patel; Omar A. Mahroo; Andrew R. Webster; for the UK Biobank Eye and Vision Consortium*
TAGS: abca4 gene, biobanks, genotype, mutation, retina, retinal diseases, alleles, cohort studies, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):31. https://doi.org/10.1167/iovs.64.7.31

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Refractive error following endoscopic vitrectomy for stage 4 retinopathy of prematurity

Katie Williams; James Wawrzynski; Elisabeth De Smit; Christopher J Hammond; Chetan Kantibhai Patel; Robert Henderson; Sui Chien Wong

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4931.

ARVO Annual Meeting Abstract June 2023

Determinants of retinal nerve fibre loss in an aging cohort

Ammar Alhadi; Zakariya Jarrar; Christopher J Hammond; Abdus Samad Ansari

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):96.

ARVO Annual Meeting Abstract June 2023

Prevalence, concordance, and heritability of posterior vitreous detachment (PVD) in a twin population

Dominic Shou Huang Wong; Zakariya Jarrar; Abdus Samad Ansari; Katie Williams; Pirro G Hysi; Omar Abdul Rahman Mahroo; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):540.

ARVO Annual Meeting Abstract June 2023

Mendelian Randomization analyses identify environmental factors that influence keratoconus risk

Pirro G Hysi; Alice E Davidson; Petra Liskova; Paul N Baird; Kathryn P Burdon; Christopher J Hammond; Alison J Hardcastle; Stephen J Tuft

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1178.

ARVO Annual Meeting Abstract June 2023

A genome wide association study of electroretinogram oscillatory potentials

ZIHE XU; Xiaofan Jiang; Alex M Tanner; Talha Soorma; Christopher J Hammond; Omar Abdul Rahman Mahroo; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1663.

ARVO Annual Meeting Abstract June 2023

Systemic mitochondrial function tests as a biomarker for susceptibility to glaucoma and neurodegeneration in an unselected ageing twin population

Abdus Samad Ansari; Zakariya Jarrar; Claire Steves; Tor Paaske Utheim; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2905.

ARVO Annual Meeting Abstract June 2023

A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease

Jelle Vehof; Amber Rhee; Mario Falchi; Frances M.K. Williams; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2876.

ARVO Annual Meeting Abstract June 2023

Ratio of temporal to nasal macular ganglion cell layer thicknesses in a twin study: correlations with age and within monozygotic and dizygotic twin pairs

Khaldoon O. Al-Nosairy; Zakariya Jarrar; Ali Lamin; Katie Williams; Sobha Sivaprasad; Michael B Hoffmann; Pirro G Hysi; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3433.

ARVO Annual Meeting Abstract June 2023

Novel genetic enrichment analyses of single cell RNA sequencing datasets identifies important cell types influencing primary open angle glaucoma and refractive error.

Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3271.

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A metabolome-wide analysis of Intraocular pressure suggests neuroinflammatory mechanisms as possible mechanisms involved in glaucoma

Are we amid a dry eye epidemic? - The increasing prevalence of dry eye disease in Europe

Exploring kinetics of the ganglion cell contribution to standard light-adapted flash electroretinograms by interocular comparison in patients with unilateral ganglion cell loss

Enhanced deep metagenomic sequencing of ocular microbes using saponification with the Nanopore platform

Epigenetic modifiers and their interactions with genetic polymorphisms in Intraocular Pressure and glaucoma

Modelling the rod-driven electroretinogram a-wave elicited by strong flashes: insights from patients with selected post-phototransduction impairments

Metabolome-wide analysis identifies two plasma metabolites associated with age-related macular degeneration

Temporal-to-Nasal Macular Ganglion Cell and Inner Plexiform Layer Ratios in a Large Adult Twin Cohort: Correlations With Age and Heritability

Changes in Refractive Error During Young Adulthood: The Effects of Longitudinal Screen Time, Ocular Sun Exposure, and Genetic Predisposition

Prevalence, Concordance, and Heritability of Vitreomacular Interface Abnormalities in a Twin Study

An Analysis of the Effect of ABCA4 p.Asn1868Ile Genotypes on Retinal Structure in 26,558 Participants in the UK Biobank

Refractive error following endoscopic vitrectomy for stage 4 retinopathy of prematurity

Determinants of retinal nerve fibre loss in an aging cohort

Prevalence, concordance, and heritability of posterior vitreous detachment (PVD) in a twin population

Mendelian Randomization analyses identify environmental factors that influence keratoconus risk

A genome wide association study of electroretinogram oscillatory potentials

Systemic mitochondrial function tests as a biomarker for susceptibility to glaucoma and neurodegeneration in an unselected ageing twin population

A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease

Ratio of temporal to nasal macular ganglion cell layer thicknesses in a twin study: correlations with age and within monozygotic and dizygotic twin pairs

Novel genetic enrichment analyses of single cell RNA sequencing datasets identifies important cell types influencing primary open angle glaucoma and refractive error.

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