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Journal Articles (7)
Meeting Abstract (6)

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Investigative Ophthalmology & Visual Science (9)
Translational Vision Science & Technology (4)

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ARVO Annual Meeting Abstract (6)
Retina (2)
Retinal Cell Biology (2)
Articles (1)
Perspective (1)
Research Opportunities (1)

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Genetics (7)
Eye Anatomy and Disorders (5)
Retina (4)
Translational Research (4)
Retinal Cell Biology (2)
Biochemistry and Molecular Biology (1)
Low Vision (1)
Nanotechnology and Regenerative Medicine (1)
Pharmacology (1)

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blindness (3)
genes (3)
vision (3)
eye (2)
fgfr2 gene (2)
fibroblast growth factor receptors (2)
gene therapy (2)
genetics (2)
mice (2)
retina (2)

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Perspective December 2024

Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs

PDF

Jacque L. Duncan; Angela Bowman; Amy Laster; Claire Gelfman; David G. Birch; Shannon E. Boye; Stephen P. Daiger; Lucian del Priore; Donald J. Zack; James T. Handa; the Foundation Fighting Blindness Scientific Advisory Board
TAGS: age-related macular degeneration, genes, genetics, retinal degeneration, disease progression, gene therapy, vision, medical management, blindness
Trans. Vis. Sci. Tech.. 2024; 13(12):28. https://doi.org/10.1167/tvst.13.12.28

Research Opportunities October 2024

Current and Future Directions in Developing Effective Treatments for PRPH2- Associated Retinal Diseases: A Workshop Report

PDF

Radha Ayyagari; Shyamanga Borooah; Todd Durham; Claire Gelfman; Angela Bowman
TAGS: genes, mutation, retinal diseases, blindness, vision
Trans. Vis. Sci. Tech.. 2024; 13(10):16. https://doi.org/10.1167/tvst.13.10.16

Retina February 2023

Identifying and Overcoming Challenges in Developing Effective Treatments for Usher 1B: A Workshop Report

PDF

Shannon E. Boye; Todd Durham; Amy Laster; Claire M. Gelfman; José-Alain Sahel
TAGS: blindness, genes, genetics, myosin viia, natural history, outcome measures, pathology, research personnel, retina, vision
Trans. Vis. Sci. Tech.. 2023; 12(2):2. https://doi.org/10.1167/tvst.12.2.2

ARVO Annual Meeting Abstract June 2021

Preclinical Evaluation of ADVM-062, a Novel Intravitreal Gene Therapy for the Treatment of Blue Cone Monochromacy

Ruslan Grishanin; Diana Cepeda; Julio Nieves; Christine Dowd; Pallavi Sharma; Alexa Levinson; Kelly Hanna; Kristina Oresic Bender; Baljit Singh; Dawn Duffield; Rathna Veeramachaneni; Mark Renz; Judith Greengard; James Ver Hoeve; Mehdi Gasmi; Claire Gelfman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1191.

Articles January 2021

Long-Term Safety Evaluation of Continuous Intraocular Delivery of Aflibercept by the Intravitreal Gene Therapy Candidate ADVM-022 in Nonhuman Primates

PDF

Szilárd Kiss; Kristina Oresic Bender; Ruslan N. Grishanin; Kelly M. Hanna; Julio D. Nieves; Pallavi Sharma; Aivan T. Nguyen; Romeo J. Rosario; Judith S. Greengard; Claire M. Gelfman; Mehdi Gasmi
TAGS: aflibercept, anti-vascular endothelial growth factor therapy, gene therapy, safety, eye, primates, retina, vascular endothelial growth factor a
Trans. Vis. Sci. Tech.. 2021; 10(1):34. https://doi.org/10.1167/tvst.10.1.34

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Intravitreal delivery of AAV2.7m8.ranibizumab suppresses exudative lesions in the NHP laser induced model of nAMD

Kristina Bender; Ruslan Grishanin; Aivan Nguyen; Pallavi Sharma; Judith Greengard; Szilard Kiss; Claire Gelfman; Mehdi Gasmi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4492.

ARVO Annual Meeting Abstract June 2020

Mouse Studies Support Intravitreal Gene Therapy for Blue Cone Monochromacy

Ruslan Grishanin; Diana Cepeda; James Ver Hoeve; Christine Dowd; Kristina Bender; Kelly Hanna; Julio Nieves; Edward Yeh; Pallavi Sharma; Claire Gelfman; Mehdi Gasmi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4499.

ARVO Annual Meeting Abstract July 2019

Immunological response and durability of expression following sequential intravitreal administration of AAV2.7m8 gene therapy to the contralateral eye in non-human primates

Diana Cepeda; Edward Yeh; Julio Nieves; Carolina Ceballos Diaz; Awilda Rosario; Judith Greengard; Claire Gelfman; Mehdi Gasmi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2910.

ARVO Annual Meeting Abstract July 2018

Delay of oscillatory potentials links animal models to diabetes in the human eye

Zsolt Ablonczy; Cristiana Giancarlo; Christopher Schillo; Kortni Violette; Dennis Guberski; Barak Yahalom; Laura Belen; Claire Gelfman; April Hall; David Hollander; Andy Whitlock

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4445.

ARVO Annual Meeting Abstract June 2015

Evaluation of a Novel PI3-kinase Inhibitor in a Murine Model of Allergic Conjunctivitis: Treatment of Chronic Inflammation in Ocular Surface Disease

Andy Whitlock; Zhenhua Huang; Yanli Wang; Laura Belen; Claire Mazow Gelfman

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4886.

Retina November 2007

Mice Lacking α/β Subunits of GlcNAc-1-Phosphotransferase Exhibit Growth Retardation, Retinal Degeneration, and Secretory Cell Lesions

PDF

Claire M. Gelfman; Peter Vogel; Tawfik M. Issa; C. Alexander Turner; Wang-Sik Lee; Stuart Kornfeld; Dennis S. Rice
TAGS: gnptab gene, growth retardation, mice, phosphotransferases, retinal degeneration, homozygote, enzymes
Invest. Ophthalmol. Vis. Sci.. 2007; 48(11):5221-5228. https://doi.org/10.1167/iovs.07-0452

Retinal Cell Biology October 2001

Downregulation of Differentiation Specific Gene Expression by Oxidative Stress in ARPE-19 Cells

PDF

Mitra Alizadeh; Mitsumasa Wada; Claire M. Gelfman; James T. Handa; Leonard M. Hjelmeland
TAGS: down-regulation, fgfr2 gene, gene expression, oxidative stress, rna, messenger, fibroblast growth factor receptors, cell survival
Invest. Ophthalmol. Vis. Sci.. 2001; 42(11):2706-2713.

Retinal Cell Biology July 2000

Expression and Splicing of FGF Receptor mRNAs during ARPE-19 Cell Differentiation In Vitro

PDF

Mitra Alizadeh; Claire M. Gelfman; Shellie R. Bench; Leonard M. Hjelmeland
TAGS: cell differentiation, fibroblast growth factor receptors, protein isoforms, rna splicing, rna, messenger, fgfr2 gene, fibroblast growth factor 2, retinal pigment cell, growth factor, reverse transcriptase polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2000; 41(8):2357-2362.

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