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Genetics July 2025

Genetic Associations of Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration

PDF

Christine A. Curcio; Robert F. Mullins; Edwin M. Stone; Lukas Goerdt; Deepayan Kar; Liyan Gao; Gerald McGwin, Jr.; Cynthia Owsley
TAGS: age-related macular degeneration, aging, eye, genetics, retinal cone, rod photoreceptors, vision, digestive tract decontamination, alleles
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):50. https://doi.org/10.1167/iovs.66.9.50

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

Hypertransmission defects, related features, and their association with vision at the aging-age-related macular degeneration (AMD) transition

Will Johnston; Sarah Kim; Deepayan Kar; Liyan Gao; Mark E. Clark; Gerald McGwin; Kenneth R Sloan; Cynthia Owsley; Christine A Curcio; Lukas Goerdt

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3469.

ARVO Annual Meeting Abstract June 2025

Lifetimes in fluorescence lifetime imaging ophthalmoscopy (FLIO) lengthen as rod mediated dark adaptation (RMDA) slows in aging and age-related macular degeneration (AMD): ALSTAR2

Lukas Goerdt; Mark E. Clark; Tracy Thomas; Liyan Gao; Gerald McGwin; Martin Hammer; Kenneth R Sloan; Cynthia Owsley; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1335.

ARVO Annual Meeting Abstract June 2025

Lower contrast sensitivity and lower visual acuity are associated with cognitive impairment: Analyses of Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI)

Aya Motoyoshi; Yu Jiang; Sally Baxter; Linda M Zangwill; Gerald McGwin; Cynthia Owsley; Cecilia S Lee; Aaron Y Lee

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2012.

ARVO Annual Meeting Abstract June 2025

Delayed Rod-Mediated Dark Adaptation in Normal Older Eyes is associated with Incident AMD and in Early AMD Eyes with AMD Progression: ALSTAR2

Cynthia Owsley; Gerald McGwin; Mark E. Clark; Liyan Gao; Lindsay Gooden; Tracy Thomas; Lukas Goerdt; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):672.

ARVO Annual Meeting Abstract June 2025

Quantitative Analysis of Deposit-Driven Age-Related Macular Degeneration: ALSTAR2 Follow-up

Nhuan Vu; Ibrahim Abboud; Aya Alhasany; Peter Racioppo; Ziyuan Chris Wang; Sohaib Fasih-Ahmad; Mark E. Clark; Christine A Curcio; Cynthia Owsley; SriniVas R Sadda; Zhihong Jewel Hu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6378.

ARVO Annual Meeting Abstract June 2025

At the beginnings of age-related macular degeneration (AMD) rod-mediated dark adaptation (RMDA), and no other visual tests, is worse at baseline in eyes that progress at 3 years: prospective data from ALSTAR2

Christine A Curcio; Gerald McGwin; Mark E. Clark; Liyan Gao; Lindsay Gooden; Tracy Thomas; Lukas Goerdt; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3619.

ARVO Annual Meeting Abstract June 2025

qAF8 is not associated with early stages of AMD: ALSTAR2 follow-up cohort

Andreas Berlin; Lukas Goerdt; Sarah Kim; Liyan Gao; Mark E. Clark; Tracy Thomas; Gerald McGwin; Jason Neal Crosson; Kenneth R Sloan; Cynthia Owsley; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3499.

Retina April 2025

Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

PDF

Lukas Goerdt; Mark E. Clark; Tracy N. Thomas; Liyan Gao; Gerald McGwin, Jr.; Martin Hammer; Jason N. Crosson; Kenneth R. Sloan; Cynthia Owsley; Christine A. Curcio
TAGS: age-related macular degeneration, aging, diagnostic imaging, eye, fluorescence, ophthalmoscopy, vision, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):56. https://doi.org/10.1167/iovs.66.4.56

Includes: Supplemental Content

Retina March 2025

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

PDF

Lukas Goerdt; Andreas Berlin; Liyan Gao; Thomas A. Swain; Sarah S. Kim; Gerald McGwin; Mark E. Clark; Deepayan Kar; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: aging, autofluorescence, eye, lutein, pigment, maps, meridians, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):61. https://doi.org/10.1167/iovs.66.3.61

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics March 2025

Age-Related Changes in Mesopic Reading Vision Across Adulthood

PDF

Boris Peñaloza; Traci-Lin Goddin; David S. Friedman; Cynthia Owsley; MiYoung Kwon
TAGS: reading (activity), vision, adult
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):40. https://doi.org/10.1167/iovs.66.3.40

Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

PDF

Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Retina August 2024

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

PDF

Lukas Goerdt; Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio; Deepayan Kar
TAGS: digestive tract decontamination, rod photoreceptors, vision, eye, aging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):25. https://doi.org/10.1167/iovs.65.10.25

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2024

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

PDF

Deepayan Kar; Mohymina Amjad; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Kenneth R. Sloan; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, aging, fovea centralis, vision, impairment, rod photoreceptors, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):40. https://doi.org/10.1167/iovs.65.8.40

ARVO Annual Meeting Abstract June 2024

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Kenneth R Sloan; Cynthia Owsley; Christine A Curcio; Deepayan Kar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2295.

ARVO Annual Meeting Abstract June 2024

Evaluation of Patient Preferences for Table-mounted and Portable Visual Field Devices in Underserved Areas

Ellen Konadu Antwi-Adjei; Thomas A. Swain; Christopher A Girkin; Cynthia Owsley; Lindsay Anne Rhodes; Matthew Fifolt; Lyne Racette

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4804.

ARVO Annual Meeting Abstract June 2024

Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) study: Report on recruitment strategy and pilot data collection

Alina Ferguson; Cari Drolet; Trina Kim; Cath Ashley; Julia Owen; Missy Takahashi; Dawn Mathies; Shay Paselio; Sally Liu Baxter; Aaron Y Lee; Linda M Zangwill; Cecilia S Lee; Gerald McGwin; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3727.

ARVO Annual Meeting Abstract June 2024

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Cynthia Owsley; Gerald McGwin; Thomas A. Swain; Mark E Clark; Tracy N Thomas; Lucas Goerdt; Kenneth R Sloan; Emily Trittschuh; Yu Jiang; Julia Owen; Cecilia S Lee; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2267.

ARVO Annual Meeting Abstract June 2024

Generation of a Multimodal Atlas of Type 2 Diabetes for Artificial Intelligence (AI-READI): Purpose and Design

Dawn Matthies; Julia Owen; Gerald McGwin; Cynthia Owsley; Sally Liu Baxter; Linda M Zangwill; Cecilia S Lee; Aaron Y Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3728.

ARVO Annual Meeting Abstract June 2024

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

Yu Jiang; Thomas A. Swain; Christine Mac Donald; Ariel Rokem; Julia P Owen; Gerald McGwin; Christine A Curcio; Kenneth R Sloan; Emily H Trittschuh; Swati Rane Levendovszky; Mark E Clark; Cynthia Owsley; Cecilia S Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):446.

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Genetic Associations of Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration

Hypertransmission defects, related features, and their association with vision at the aging-age-related macular degeneration (AMD) transition

Lifetimes in fluorescence lifetime imaging ophthalmoscopy (FLIO) lengthen as rod mediated dark adaptation (RMDA) slows in aging and age-related macular degeneration (AMD): ALSTAR2

Lower contrast sensitivity and lower visual acuity are associated with cognitive impairment: Analyses of Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI)

Delayed Rod-Mediated Dark Adaptation in Normal Older Eyes is associated with Incident AMD and in Early AMD Eyes with AMD Progression: ALSTAR2

Quantitative Analysis of Deposit-Driven Age-Related Macular Degeneration: ALSTAR2 Follow-up

At the beginnings of age-related macular degeneration (AMD) rod-mediated dark adaptation (RMDA), and no other visual tests, is worse at baseline in eyes that progress at 3 years: prospective data from ALSTAR2

qAF8 is not associated with early stages of AMD: ALSTAR2 follow-up cohort

Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

Age-Related Changes in Mesopic Reading Vision Across Adulthood

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Evaluation of Patient Preferences for Table-mounted and Portable Visual Field Devices in Underserved Areas

Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) study: Report on recruitment strategy and pilot data collection

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Generation of a Multimodal Atlas of Type 2 Diabetes for Artificial Intelligence (AI-READI): Purpose and Design

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

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