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ARVO Annual Meeting Abstract June 2025

The co-transduction conundrum: Improving dual rAAV delivery through co-administration of capsid serotypes with complementary tropism

Rachel L Fehrman; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5960.

ARVO Annual Meeting Abstract June 2025

Development of a retinal tissue equivalent (RTE) model system as an alternative to iPSC derived organoids

Ramesh Periasamy; Allison Hall; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5277.

ARVO Annual Meeting Abstract June 2025

Arterial cannulation corroborates diastolic timing in a three-peak laser speckle contrast imaging waveform in mice

Alexander Joseph Tate; Gary C Mouradian; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4922.

ARVO Annual Meeting Abstract June 2025

Early detection of vascular dysfunction in diabetic retinopathy using Laser Speckle Contrast Imaging

Elizabeth J Alessio; Alexander Joseph Tate; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4833.

ARVO Annual Meeting Abstract June 2025

Characterization of a primary porcine “drusen in a dish” model system demonstrates accumulation of sub-RPE deposits closely mimicking the composition of human AMD druse.

Daniel M Lipinski; Erika Shaw

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3244.

Retinal Cell Biology March 2025

Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen

PDF

Erika M. Shaw; David M. Anderson; Ramesh Periasamy; Kevin L. Schey; Christine A. Curcio; Daniel M. Lipinski
TAGS: drusen, suidae, age-related macular degeneration, pigment
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):18. https://doi.org/10.1167/iovs.66.3.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Generation of a ‘minimal’ recombinant adeno-associated virus (rAAV) virion for use as a universal injection control

Samiah Ziadeh; Ramesh Periasamy; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2225.

ARVO Annual Meeting Abstract June 2024

Evaluation of rAAV Serotype tropism in the murine anterior chamber for the treatment of glaucoma.

Ramesh Periasamy; Kristina J Chern; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3545.

ARVO Annual Meeting Abstract June 2024

Laser speckle contrast imaging detects retinal hemodynamic alterations in the 5xFAD model of Alzheimer’s disease

Alexander Joseph Tate; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4931.

ARVO Annual Meeting Abstract June 2024

Lipid Nanoparticle mediated dsDNA delivery to the neural retina

Rachel Fehrman; Milan Gautam; Gaurav Sahay; Renee Christine Ryals; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5302.

ARVO Annual Meeting Abstract June 2023

Modification of rAAV capsid to improve retinal vascular endothelial tropism

Ramesh Periasamy; Dwani Patel; Sanford L Boye; Shannon E Boye; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):768.

ARVO Annual Meeting Abstract June 2023

Effects of a prostaglandin-based rAAV gene therapy for the treatment of glaucoma in DBA/2J mice

Kristina J Chern; Samiah J Ziadeh; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1917.

ARVO Annual Meeting Abstract June 2023

Development of an automated pipeline for laser speckle contrast imaging analysis reveals novel retinal pulseform features

Alexander J Tate; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2383.

ARVO Annual Meeting Abstract June 2023

Feasibility of multiple rAAV vector approaches for large gene delivery in the murine retina

Rachel Fehrman; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3847.

Retina August 2022

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution

PDF

Dwani D. Patel; Damien Marsic; Ramesh Periasamy; Sergei Zolotukhin; Daniel M. Lipinski
TAGS: capsid, pericytes, spatial vectors, libraries
Trans. Vis. Sci. Tech.. 2022; 11(8):28. https://doi.org/10.1167/tvst.11.8.28

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Determining the cellular transduction efficacy of multiple rAAV vectors in the murine retina

Rachel Fehrman; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):70 – A0043.

ARVO Annual Meeting Abstract June 2022

Improving retinal vascular endothelial cell tropism through rational rAAV capsid design.

Ramesh Periasamy; Dwani D Patel; Sanford L Boye; Shannon E Boye; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):66 – A0039.

ARVO Annual Meeting Abstract June 2022

Safety and efficacy of recombinant adeno-associated virus (rAAV) mediated transduction in the anterior chamber of the African Green Monkey ( Chlorocebus sabaeus )

Kristina J Chern; Gavin J Marcoe; Kimica Isaac; Zendorf Gumbs; Dexter Fahie; Melissa O'Conner; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):59 – A0032.

ARVO Annual Meeting Abstract June 2022

Exploring the survival of transplanted hiPSC-derived photoreceptors in the 13-lined ground squirrel

Ching Tzu Yu; Sangeetha Kandoi; Ramesh Periasamy; Hannah M Follett; Phyllis Summerfelt; Chloe Guillaume; Owen Bowie; Nicole Manfredonia; Dana Merriman; Thomas B Connor; Daniel M Lipinski; Joseph Carroll; Deepak A Lamba

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1113.

ARVO Annual Meeting Abstract June 2022

Characterization of a primary porcine RPE ‘drusen in a dish’ cell culture model

Erika Shaw; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3160 – F0434.

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The co-transduction conundrum: Improving dual rAAV delivery through co-administration of capsid serotypes with complementary tropism

Development of a retinal tissue equivalent (RTE) model system as an alternative to iPSC derived organoids

Arterial cannulation corroborates diastolic timing in a three-peak laser speckle contrast imaging waveform in mice

Early detection of vascular dysfunction in diabetic retinopathy using Laser Speckle Contrast Imaging

Characterization of a primary porcine “drusen in a dish” model system demonstrates accumulation of sub-RPE deposits closely mimicking the composition of human AMD druse.

Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen

Generation of a ‘minimal’ recombinant adeno-associated virus (rAAV) virion for use as a universal injection control

Evaluation of rAAV Serotype tropism in the murine anterior chamber for the treatment of glaucoma.

Laser speckle contrast imaging detects retinal hemodynamic alterations in the 5xFAD model of Alzheimer’s disease

Lipid Nanoparticle mediated dsDNA delivery to the neural retina

Modification of rAAV capsid to improve retinal vascular endothelial tropism

Effects of a prostaglandin-based rAAV gene therapy for the treatment of glaucoma in DBA/2J mice

Development of an automated pipeline for laser speckle contrast imaging analysis reveals novel retinal pulseform features

Feasibility of multiple rAAV vector approaches for large gene delivery in the murine retina

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution

Determining the cellular transduction efficacy of multiple rAAV vectors in the murine retina

Improving retinal vascular endothelial cell tropism through rational rAAV capsid design.

Safety and efficacy of recombinant adeno-associated virus (rAAV) mediated transduction in the anterior chamber of the African Green Monkey ( Chlorocebus sabaeus )

Exploring the survival of transplanted hiPSC-derived photoreceptors in the 13-lined ground squirrel

Characterization of a primary porcine RPE ‘drusen in a dish’ cell culture model

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