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ARVO Annual Meeting Abstract June 2024

In vivo and ex vivo characterization of photoreceptor cell replacement therapy using scaffolds in a non-human primate model of vision loss

Soumaya Belhadj; Agustin Luz Madrigal; Laura Patak; Jacqueline Gayet; Hector Baez; Jennifer LaPorta; William Fischer; Nathaniel Foley; Arvydas Maminishkis; Kapil Bharti; Juan Amaral; Vamsi Gullapalli; David Allen Diloreto; Teresa Puthussery; David M Gamm; Juliette E Mcgregor

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3825.

ARVO Annual Meeting Abstract June 2024

CRISPR VISION Program: Nonviral Genome Editing to Treat Congenital Blindness

Bikash R Pattnaik; Krishanu Saha; David M Gamm; Shaoqin Sarah Saha; T Michael Nork; William L Murphy; Rina Mepani; Mary HaakFrendscho

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4266.

ARVO Annual Meeting Abstract June 2024

Proteomics discovery of putative Müller glia synaptogenic factors to develop future retinal repair strategies

Emily Welby; Linda Berg Luecke; Melinda Melinda Wojtkiewicz; Rebekah L Gundry; David M Gamm; Brian Link; Allison D Ebert

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1651.

ARVO Annual Meeting Abstract June 2024

NRL-centered Rod Gene Regulatory Network identified by gene delivery in a patient iPSC-derived retinal organoid model of NRL-retinopathy

Zepeng Qu; Carolina Beltrame Del Debbio; Kamil Kruczek; Laura Campello; Xulong Liang; Nivedita Singh; Zachary Batz; Matthew Brooks; Suja Hiriyanna; Donald J Zack; David M Gamm; Anand Swaroop

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1566.

ARVO Annual Meeting Abstract June 2024

Analyzing mRNA isoforms in human stem cell-derived retinal neurons using long-read transcriptomics

Casey J Keuthan; Sowmya Parthiban; Yen Yu Chang; Xiaoli Chang; Ethan Yan; Cynthia Berlinicke; Sheridan Cavalier; Corina Anastasaki; David Gutmann; David M Gamm; Yuan Zhu; Winston Timp; Stephanie Hicks; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4697.

ARVO Annual Meeting Abstract June 2024

Engineered tRNA to overcome nonsense mutation for the rescue of Kir7.1 physiological function

Enes AKYUZ; Pawan Shahi; Divya Sinha; Giovanni M. Hanstad; Lionel Gissot; Ahmad Al Saneh; David M Gamm; Christopher A Ahern; Bikash R Pattnaik

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6092.

ARVO Annual Meeting Abstract June 2023

Silica nanocapsules as a nonviral delivery platform for iPSC-RPE

Divya Sinha; Yao Tong; Maria A Fernandez Zepeda; Giovanni Hanstad; Emma C Nelson; Cole O Theisen; Shaoqin Gong; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):774.

ARVO Annual Meeting Abstract June 2023

Structural and functional assessment after subretinal transplantation of human iPSC-derived photoreceptor precursors in a canine model of end stage retinal degeneration

William A Beltran; Ana Ripolles-Garcia; Yu Sato; Alexandra Gray; John H Wolfe; Agustin Luz-Madrigal; Michael J Philipps; David M Gamm; Geoffrey K Aguirre; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):766.

ARVO Annual Meeting Abstract June 2023

Defining the molecular signature of red/green cone photoreceptor precursors using a novel human pluripotent stem cell (hPSC) cone-rod reporter line

Praveen Joseph Susai Manickam; Elizabeth Capowski; Michael J Philipps; Steven J Mayerl; Kimberly Lauren Edwards; Mai N Xiong; Maria A Fernandez Zepeda; Emma C Nelson; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3222.

ARVO Annual Meeting Abstract June 2023

Incorporation of hPSC-derived photoreceptors and RPE cells into microfabricated, honeycomb-patterned microscaffolds for outer retinal reconstruction

Agustin Luz Madrigal; In–Kyu Lee; Ruosen Xie; Seunghwan Min; Jingcheng Zhu; Jiahe Jin; Allison L. Ludwig; M. Joseph Phillips; Shaoqin Gong; Zhenqiang Ma; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3173.

ARVO Annual Meeting Abstract June 2023

In-depth molecular characterization of retinal organoids from pig pluripotent stem cells

Kimberly Lauren Edwards; Praveen Joseph Susai Manickam; Tyler-Serie Ganser; Michael J Philipps; Li-Fang Chu; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3167.

ARVO Annual Meeting Abstract June 2023

Surgical approach for transplantation of a photoreceptor precursors patch in a swine Commotio Retinae model

Juan Amaral; Richard J Blanch; Irina Bunea; Ruchi Sharma; Jair Montford; Agustin Luz-Madrigal; Kimberly Lauren Edwards; Francesca Barone; Michael J Phillips; Arvydas Maminishkis; David M Gamm; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3713.

ARVO Annual Meeting Abstract June 2022

Triple drug immunosuppression for xenotransplantation of human photoreceptor precursor cells in the canine retina.

Ana Ripolles-Garcia; Natalia Dolgova; M. Joseph Phillips; Svetalana Savina; Allison Ludwig; Sara Stuedemann; John H Wolfe; Oliver Garden; David M Gamm; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):53 – A0026.

ARVO Annual Meeting Abstract June 2022

Functional development of cone photoreceptors in human stem cell derived retinal organoids

Aindrila Saha; Elizabeth Capowski; Maria A. Fernandez Zepeda; Emma Clare Finnegan C.F. Nelson; David M Gamm; Raunak Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1359 – F0290.

ARVO Annual Meeting Abstract June 2022

Robust generation of retinal organoids from porcine induced pluripotent stem cells.

Kimberly L. Edwards; Li-Fang Chu; Yolana C. Martin; James A. Thomson; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3727 – F0333.

Special Issue November 2021

Outer Retinal Cell Replacement: Putting the Pieces Together

PDF

Allison L. Ludwig; David M. Gamm
TAGS: cell therapy, donors, transplantation, transfer technique, safety, retina, cell transplantation, animal model
Trans. Vis. Sci. Tech.. 2021; 10(10):15. https://doi.org/10.1167/tvst.10.10.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Subretinal transplantation and survival of hESC-derived photoreceptor precursor cells in normal canine eyes

Ana Ripolles Garcia; Valerie Dufour; Joe Phillips; Natalia Dolgova; Allison Ludwig; Sara Stuedemann; Svetlana Savina; John H Wolfe; Karina E Guziewicz; Oliver Garden; David M Gamm; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):796.

ARVO Annual Meeting Abstract June 2020

CRISPR Base Editing; A feasible treatment for inherited retinopathy

Meha Kabra; Allison Spillane; Pawan Shahi; David M Gamm; Amr A Abdeen; Krishanu Saha; Bikash R Pattnaik

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2451.

ARVO Annual Meeting Abstract June 2020

Genome-Edited LCA16 iPSC-RPE Shows Rescue of Kir7.1 Channel

Pawan Shahi; Meha Kabra; Amr A Abdeen; Yuyuan Wang; Kim Edwards; Divya Sinha; David M Gamm; Krishanu Saha; Sarah Gong; Bikash R Pattnaik

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2453.

ARVO Annual Meeting Abstract June 2020

Assessing hPSC-derived retinal neuron synapse formation in vitro via monosynaptic retrograde tracing

Steven Mayerl; Allison Ludwig; Yu Gao; Xinyu Zhao; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2506.

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In vivo and ex vivo characterization of photoreceptor cell replacement therapy using scaffolds in a non-human primate model of vision loss

CRISPR VISION Program: Nonviral Genome Editing to Treat Congenital Blindness

Proteomics discovery of putative Müller glia synaptogenic factors to develop future retinal repair strategies

NRL-centered Rod Gene Regulatory Network identified by gene delivery in a patient iPSC-derived retinal organoid model of NRL-retinopathy

Analyzing mRNA isoforms in human stem cell-derived retinal neurons using long-read transcriptomics

Engineered tRNA to overcome nonsense mutation for the rescue of Kir7.1 physiological function

Silica nanocapsules as a nonviral delivery platform for iPSC-RPE

Structural and functional assessment after subretinal transplantation of human iPSC-derived photoreceptor precursors in a canine model of end stage retinal degeneration

Defining the molecular signature of red/green cone photoreceptor precursors using a novel human pluripotent stem cell (hPSC) cone-rod reporter line

Incorporation of hPSC-derived photoreceptors and RPE cells into microfabricated, honeycomb-patterned microscaffolds for outer retinal reconstruction

In-depth molecular characterization of retinal organoids from pig pluripotent stem cells

Surgical approach for transplantation of a photoreceptor precursors patch in a swine Commotio Retinae model

Triple drug immunosuppression for xenotransplantation of human photoreceptor precursor cells in the canine retina.

Functional development of cone photoreceptors in human stem cell derived retinal organoids

Robust generation of retinal organoids from porcine induced pluripotent stem cells.

Outer Retinal Cell Replacement: Putting the Pieces Together

Subretinal transplantation and survival of hESC-derived photoreceptor precursor cells in normal canine eyes

CRISPR Base Editing; A feasible treatment for inherited retinopathy

Genome-Edited LCA16 iPSC-RPE Shows Rescue of Kir7.1 Channel

Assessing hPSC-derived retinal neuron synapse formation in vitro via monosynaptic retrograde tracing

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