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Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

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Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Retina August 2024

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

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Lukas Goerdt; Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio; Deepayan Kar
TAGS: digestive tract decontamination, rod photoreceptors, vision, eye, aging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):25. https://doi.org/10.1167/iovs.65.10.25

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2024

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

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Deepayan Kar; Mohymina Amjad; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Kenneth R. Sloan; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, aging, fovea centralis, vision, impairment, rod photoreceptors, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):40. https://doi.org/10.1167/iovs.65.8.40

ARVO Annual Meeting Abstract June 2024

Contrast sensitivity function using a prototype gaze tracking-based virtual reality headset in age-related macular degeneration (AMD)

Deepayan Kar; Alex McKeown; Stephan Michels; Nicola Grüninger; Stephan Wyder; Matthias Pfister; Lukas Scheibler

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1483.

ARVO Annual Meeting Abstract June 2024

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Kenneth R Sloan; Cynthia Owsley; Christine A Curcio; Deepayan Kar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2295.

ARVO Annual Meeting Abstract June 2024

Volume Electron Microscopy Reconstruction of Human Subfoveal Bruch’s Membrane/Choriocapillaris Transport Complex

Maximilian Lindell; Deepayan Kar; Jeffrey Messinger; Yeon Jin Kim; Orin Packer; Ursula Schmidt-Erfurth; Michael Marsh; Dennis M Dacey; Christine A Curcio; Andreas Pollreisz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4951.

Review March 2024

Age-Related Macular Degeneration, a Mathematically Tractable Disease

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Christine A. Curcio; Deepayan Kar; Cynthia Owsley; Kenneth R. Sloan; Thomas Ach
TAGS: age-related macular degeneration, aging, drusen, eye, fovea centralis, lutein, macula lutea, photoreceptors, retina, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):4. https://doi.org/10.1167/iovs.65.3.4

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging December 2023

Volumetric Reconstruction of a Human Retinal Pigment Epithelial Cell Reveals Specialized Membranes and Polarized Distribution of Organelles

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Maximilian Lindell; Deepayan Kar; Aleksandra Sedova; Yeon Jin Kim; Orin S. Packer; Ursula Schmidt-Erfurth; Kenneth R. Sloan; Mike Marsh; Dennis M. Dacey; Christine A. Curcio; Andreas Pollreisz
TAGS: organelles, reconstructive surgical procedures, retinal pigment cell, tissue membrane, mitochondria, photoreceptors, cell body, diagnostic imaging, volume, endoplasmic reticulum
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):35. https://doi.org/10.1167/iovs.64.15.35

Multidisciplinary Ophthalmic Imaging September 2023

Choriocapillaris Impairment Is Associated With Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration

PDF

Deepayan Kar; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, dark adaptation, drusen, eye, fluid flow, impairment, rod photoreceptors, vision, visual impairment, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):41. https://doi.org/10.1167/iovs.64.12.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Deep learning assisted 3D ultrastructural reconstruction of human retinal pigment epithelium (RPE) nuclei reveals a structured pattern of nuclear pores

Maximilian Lindell; Deepayan Kar; Yeon Jin Kim; Zachary Arsenault; Orin Packer; Ursula Schmidt-Erfurth; Mike Marsh; Dennis M Dacey; Christine A. Curcio; Andreas Pollreisz

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2988.

ARVO Annual Meeting Abstract June 2023

Choriocapillaris flow impairment under the fovea is associated with delayed rod-mediated dark adaptation in the perifovea of eyes with early and intermediate age-related macular degeneration: ALSTAR2 baseline

Deepayan Kar; Giulia Corradetti; Mohymina Amjad; Thomas A. Swain; Mark E. Clark; Gerald McGwin; Cynthia Owsley; Kenneth R Sloan; SriniVas R Sadda; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):921.

Retina July 2022

How Vision Is Impaired From Aging to Early and Intermediate Age-Related Macular Degeneration: Insights From ALSTAR2 Baseline

PDF

Cynthia Owsley; Thomas A. Swain; Gerald McGwin, Jr.; Mark E. Clark; Deepayan Kar; Jason N. Crosson; Christine A. Curcio
TAGS: age-related macular degeneration, aging, eye, vision, digestive tract decontamination
Trans. Vis. Sci. Tech.. 2022; 11(7):17. https://doi.org/10.1167/tvst.11.7.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Human photoreceptor mitochondria (PR-Mit) are molecularly unique in healthy aged retina and outer retinal tubulation (ORT) of age-related macular degeneration (AMD)

Dongfeng Cao; Jeffrey D Messinger; Deepayan Kar; Thomas Ach; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2584 – F0467.

ARVO Annual Meeting Abstract June 2022

Morphology of the human retinal pigment epithelium (RPE) basal transport complex in fovea and parafovea revealed by volume electron microscopy

Deepayan Kar; Orin Packer; Yeon Jin Kim; Andreas Pollreisz; Dennis M Dacey; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4626 – F0418.

ARVO Annual Meeting Abstract June 2022

Three-dimensional reconstruction of human retinal pigment epithelium (RPE) permits a novel view of the RPE – photoreceptor outer segment (OS) interface

Andreas Pollreisz; Aleksandra Sedova; Maximilian Lindell; Zachary Arsenault; Orin Packer; Deepayan Kar; Yeon Jin Kim; Kenneth R Sloan; Ursula Schmidt-Erfurth; Mike Marsh; Christine A Curcio; Dennis M Dacey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):871.

Optica Fall Vision Meeting Abstract February 2022

Contributed Session I: Mitochondrial distribution in the outer plexiform layer of human retina - Does it correlate with reflectivity in OCT?

Deepayan Kar; Yeon Jin Kim; Orin Packer; Dennis M Dacey; Christine A Curcio
TAGS: mitochondria, retina
Journal of Vision. 2022; 22(3):2. https://doi.org/10.1167/jov.22.3.2

Retina August 2021

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

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Dongfeng Cao; Belinda Leong; Jeffrey D. Messinger; Deepayan Kar; Thomas Ach; Lawrence A. Yannuzzi; K. Bailey Freund; Christine A. Curcio
TAGS: age-related macular degeneration, atrophic condition of skin, atrophy, cell transdifferentiation, diagnostic imaging, donors, eye, immunohistochemistry, optical coherence tomography, phenotype
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):34. https://doi.org/10.1167/iovs.62.10.34

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Morphological variants of mitochondria in neurons surrounding the deep capillary plexus in human retina

Deepayan Kar; Yeon Jin Kim; Orin Packer; Dennis M Dacey; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2220.

ARVO Annual Meeting Abstract June 2021

Reconstruction of apical processes (AP) originating from human retinal pigment epithelium (RPE) cell bodies by 3D connectomics technology

Aleksandra Sedova; Maximilian Lindell; Kenneth R Sloan; Deepayan Kar; Orin Packer; Yeon Jin Kim; Ursula Schmidt-Erfurth; Dennis M Dacey; Christine A Curcio; Andreas Pollreisz

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3022.

ARVO Annual Meeting Abstract June 2021

Multiscale clinicopathologic correlation of canonical and non-canonical intraretinal neovascularization in age-related macular degeneration (AMD)

Jeffrey D. Messinger; Ling Chen; Andreas Berlin; Deepayan Kar; Tommaso Bacci; Chandrakumar Balaratnasingham; Randev Mendes; Daniela Ferrara; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):654.

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Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

Contrast sensitivity function using a prototype gaze tracking-based virtual reality headset in age-related macular degeneration (AMD)

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Volume Electron Microscopy Reconstruction of Human Subfoveal Bruch’s Membrane/Choriocapillaris Transport Complex

Age-Related Macular Degeneration, a Mathematically Tractable Disease

Volumetric Reconstruction of a Human Retinal Pigment Epithelial Cell Reveals Specialized Membranes and Polarized Distribution of Organelles

Choriocapillaris Impairment Is Associated With Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration

Deep learning assisted 3D ultrastructural reconstruction of human retinal pigment epithelium (RPE) nuclei reveals a structured pattern of nuclear pores

Choriocapillaris flow impairment under the fovea is associated with delayed rod-mediated dark adaptation in the perifovea of eyes with early and intermediate age-related macular degeneration: ALSTAR2 baseline

How Vision Is Impaired From Aging to Early and Intermediate Age-Related Macular Degeneration: Insights From ALSTAR2 Baseline

Human photoreceptor mitochondria (PR-Mit) are molecularly unique in healthy aged retina and outer retinal tubulation (ORT) of age-related macular degeneration (AMD)

Morphology of the human retinal pigment epithelium (RPE) basal transport complex in fovea and parafovea revealed by volume electron microscopy

Three-dimensional reconstruction of human retinal pigment epithelium (RPE) permits a novel view of the RPE – photoreceptor outer segment (OS) interface

Contributed Session I: Mitochondrial distribution in the outer plexiform layer of human retina - Does it correlate with reflectivity in OCT?

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

Morphological variants of mitochondria in neurons surrounding the deep capillary plexus in human retina

Reconstruction of apical processes (AP) originating from human retinal pigment epithelium (RPE) cell bodies by 3D connectomics technology

Multiscale clinicopathologic correlation of canonical and non-canonical intraretinal neovascularization in age-related macular degeneration (AMD)

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