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ARVO Annual Meeting Abstract June 2024

Rho-kinase pathway inhibition for proliferative vitreoretinopathy: assessing the therapeutic potential of netarsudil

Jeysson Fabian Sanchez-Suarez; Said Arevalo-Alquichire; William Phillip Miller; Dhanesh Amarnani; Karim W. Barake; Max Semegran; Michael O'Hare; Leo A Kim

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6060.

ARVO Annual Meeting Abstract June 2021

Identification of Drug Candidates using a Patient-Derived Model of Proliferative Vitreoretinopathy

Dhanesh Amarnani; Santiago Delgado-Tirado; Lucia Gonzalez-Buendia; Michael O'Hare; Whitney A Greene; Heuy-Ching Hetty Wang; Joseph Arboleda-Velasquez; Leo A Kim

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3643.

ARVO Annual Meeting Abstract June 2021

Effect of Rho-kinase Inhibition on a Patient-Derived Model of Proliferative Vitreoretinopathy

Leslie Ramos; Dhanesh Amarnani; Nakul Singh; Leo A Kim

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3641.

Articles July 2020

Characterization of a Murine Model of Oxazolone-Induced Orbital Inflammation

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Dhanesh Amarnani; Angie V. Sanchez; Lindsay L. Wong; Brandon V. Duffy; Leslie Ramos; Suzanne K. Freitag; Diane R. Bielenberg; Leo A. Kim; Nahyoung Grace Lee
TAGS: mice, orbital infections, inflammations and irritations, oxazolone, cytokine
Trans. Vis. Sci. Tech.. 2020; 9(8):26. https://doi.org/10.1167/tvst.9.8.26

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Single-cell RNA-seq Analysis of Membranes in Proliferative Vitreoretinopathy Reveals RUNX1 Regulation of Epithelial-Mesenchymal Transition

Leo A Kim; Santiago Delgado-Tirado; Lucia Gonzalez-Buendia; Dhanesh Amarnani; Elizabeth Rossin; John B Miller; Dean Eliott; Joseph Arboleda-Velasquez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3057.

ARVO Annual Meeting Abstract July 2019

Topical application of a Runx1 inhibiting nanoemulsion curbs choroidal neovascularization in a laser injury model.

Santiago Delgado-Tirado; Dhanesh Amarnani; Joseph Arboleda-Velasquez; Leo A. Kim

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3271.

ARVO Annual Meeting Abstract July 2019

PCL Nanoparticles for Retinal Drug Delivery of a Small Molecule Inhibitor of RUNX1

Daniela Isaacs-Bernal; Dhanesh Amarnani; Santiago Delgado-Tirado; Hannah Whitmore; Leo A. Kim; Joseph Arboleda-Velasquez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3355.

ARVO Annual Meeting Abstract July 2019

An Explant Model of Human Proliferative Vitreoretinopathy Uncovers Synergistic Effects of Methotrexate and RUNX1 inhibition

Joseph Arboleda-Velasquez; Dhanesh Amarnani; Leslie Ramos; Santiago Delgado-Tirado; Leo A. Kim

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6419.

ARVO Annual Meeting Abstract July 2019

In vitro analysis of RUNX1 and VEGF pathway interactions

Hannah Whitmore; Dhanesh Amarnani; Santiago Delgado-Tirado; Joseph Arboleda-Velasquez; Leo A. Kim

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2687.

ARVO Annual Meeting Abstract July 2019

RUNX1 Regulation of Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy

Dhanesh Amarnani; Leslie Ramos; Santiago Delgado-Tirado; Whitney Greene; Heuy-Ching Hetty Wang; Leo A. Kim; Joseph Arboleda-Velasquez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5811.

ARVO Annual Meeting Abstract July 2018

An in-vivo model of proliferative vitreoretinopathy by intravitreal injection of cells from human-derived PVR membranes in rabbits.

Santiago Delgado-Tirado; Dhanesh Amarnani; Leo A Kim; Joseph F. Arboleda-Velasquez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4219.

Retina August 2017

Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy

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Dhanesh Amarnani; Arturo Israel Machuca-Parra; Lindsay L. Wong; Christina K. Marko; James A. Stefater; Tomasz P. Stryjewski; Dean Eliott; Joseph F. Arboleda-Velasquez; Leo A. Kim
TAGS: methotrexate, tissue membrane, vitreoretinopathy, proliferative, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):3940-3949. https://doi.org/10.1167/iovs.16-20912

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Chloroquine-induced Retinal Toxicity In Vitro and In Vivo

Dhanesh Amarnani; Eric Kim; Patricia A D'Amore; Leo A Kim

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1608.

ARVO Annual Meeting Abstract June 2017

The PPAR-γ Agonist Troglitazone Protects RPE Cells from Oxidized LDL Induced NLRP3-inflammasome–Mediated Cell Death

Ashley Mackey; Gopalan Gnanaguru; Eun Young Choi; Dhanesh Amarnani; Patricia A D'Amore; Yin Shan Eric Ng

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2288.

ARVO Annual Meeting Abstract June 2017

Inhibition of Runx1 by the Ro5-3335 benzodiazepine derivative reduces aberrant retinal angiogenesis

Leo A Kim; Jonathan D. Lam; Angie Sanchez; Dhanesh Amarnani; Jonathan Cardona-Velez; Joseph Arboleda-Velasquez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4029.

ARVO Annual Meeting Abstract September 2016

Chloroquine toxicity of the retinal pigment epithelium and retina in vitro and a mouse model of retinal toxicity

Dhanesh Amarnani; Leo A Kim; Patricia A D'Amore; Lindsay Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6040.

ARVO Annual Meeting Abstract September 2016

CD36-mediated uptake of oxidized LDL induces retinal pigment epithelial cell death through NLRP3 inflammasome activation

Gopalan Gnanaguru; Ariel Choi; Dhanesh Amarnani; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6556.

Retinal Cell Biology September 2016

Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

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Gopalan Gnanaguru; Ariel R. Choi; Dhanesh Amarnani; Patricia A. D'Amore
TAGS: cd36 antigens, lipoproteins, low-density lipoproteins, retinal pigment cell, inflammasomes
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4704-4712. https://doi.org/10.1167/iovs.15-18663

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

A Novel Murine Model of Orbital Inflammation

N. Grace Lee; Lindsay L. Wong; Dhanesh Amarnani; Suzanne K Freitag; Diane Bielenberg; Patricia A D'Amore; Leo A Kim

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3426.

ARVO Annual Meeting Abstract June 2015

Analysis and culture of cells from patient-derived membranes in proliferative diabetic retinopathy

Leo A Kim; Lindsay L. Wong; Dhanesh Amarnani; Alex A. Bigger-Allen; Yang Hu; Christina Marko; Vinay Shah; Dean Eliott; Joseph F Arboleda-Velasquez; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4683.

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Rho-kinase pathway inhibition for proliferative vitreoretinopathy: assessing the therapeutic potential of netarsudil

Identification of Drug Candidates using a Patient-Derived Model of Proliferative Vitreoretinopathy

Effect of Rho-kinase Inhibition on a Patient-Derived Model of Proliferative Vitreoretinopathy

Characterization of a Murine Model of Oxazolone-Induced Orbital Inflammation

Single-cell RNA-seq Analysis of Membranes in Proliferative Vitreoretinopathy Reveals RUNX1 Regulation of Epithelial-Mesenchymal Transition

Topical application of a Runx1 inhibiting nanoemulsion curbs choroidal neovascularization in a laser injury model.

PCL Nanoparticles for Retinal Drug Delivery of a Small Molecule Inhibitor of RUNX1

An Explant Model of Human Proliferative Vitreoretinopathy Uncovers Synergistic Effects of Methotrexate and RUNX1 inhibition

In vitro analysis of RUNX1 and VEGF pathway interactions

RUNX1 Regulation of Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy

An in-vivo model of proliferative vitreoretinopathy by intravitreal injection of cells from human-derived PVR membranes in rabbits.

Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy

Chloroquine-induced Retinal Toxicity In Vitro and In Vivo

The PPAR-γ Agonist Troglitazone Protects RPE Cells from Oxidized LDL Induced NLRP3-inflammasome–Mediated Cell Death

Inhibition of Runx1 by the Ro5-3335 benzodiazepine derivative reduces aberrant retinal angiogenesis

Chloroquine toxicity of the retinal pigment epithelium and retina in vitro and a mouse model of retinal toxicity

CD36-mediated uptake of oxidized LDL induces retinal pigment epithelial cell death through NLRP3 inflammasome activation

Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

A Novel Murine Model of Orbital Inflammation

Analysis and culture of cells from patient-derived membranes in proliferative diabetic retinopathy

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