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Glaucoma November 2024

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

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Sarah E. Quillen; Elizabeth C. Kimball; Kelsey A. Ritter-Gordy; Liya Du; Zhuochen Yuan; Mary E. Pease; Salaheddine Madhoun; Thao D. Nguyen; Thomas V. Johnson; Harry A. Quigley; Ian F. Pitha
TAGS: astrocytes, did not receive therapy or drug, eye, glaucoma, mice, neuroprotection, optic nerve disorders, phosphotransferases, proteins, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):43. https://doi.org/10.1167/iovs.65.13.43

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

A novel glaucoma model using explanted porcine eyes capable of assessing axonal transport block and lamina cribrosa cellular responses

Elizabeth Cone Cone Kimball; Sarah Quillen; Mary Ellen Pease; Kelsey Ritter-Gordy; Thomas Vincent Johnson; Ian Pitha; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6136.

ARVO Annual Meeting Abstract June 2024

Effects of topical Rho kinase inhibitor, ripasudil, on murine optic nerve astrocytes in a glaucoma model

Kelsey Ritter-Gordy; Elizabeth Cone Cone Kimball; Sarah Quillen; Cameron A Czerpak; Zhuochen Yuan; Mary Ellen Pease; Thao D Nguyen; Thomas Vincent Johnson; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6774.

ARVO Annual Meeting Abstract June 2024

Effects of topical ripasudil on response of mouse optic nerve to experimental glaucoma and nerve crush

Sarah Quillen; Elizabeth Cone Cone Kimball; Kelsey Ritter-Gordy; Mary Ellen Pease; Ian Pitha; Thomas Vincent Johnson; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):703.

Glaucoma December 2023

Comparison of the Biomechanics of the Mouse Astrocytic Lamina Cribrosa Between Glaucoma and Optic Nerve Crush Models

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Arina Korneva; Elizabeth C. Kimball; Thomas V. Johnson; Sarah E. Quillen; Mary E. Pease; Harry A. Quigley; Thao D. Nguyen
TAGS: eye, glaucoma, intraocular pressure, mice, optic nerve, biomechanics, cribriform plate, axon
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):14. https://doi.org/10.1167/iovs.64.15.14

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Dissociation enzyme treatment alters strain response of astrocytic lamina in explanted mouse optic nerve head

Arina Korneva; Elizabeth Cone-Kimball; Thao D. Nguyen; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2375.

Glaucoma September 2020

Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve

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Yik Tung Tracy Ling; Mary E. Pease; Joan L. Jefferys; Elizabeth C. Kimball; Harry A. Quigley; Thao D. Nguyen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):14. https://doi.org/10.1167/iovs.61.11.14

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

The Role of Aquaporins in the Optic Nerve Head Astrocytes in Experimental Glaucoma

Elizabeth Cone Cone-Kimball; Julie Schaub; Sarah Quillen; Mary Ellen Pease; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2004.

ARVO Annual Meeting Abstract June 2020

Amyloid precursor protein transport block evaluation as a biomarker for experimental mouse glaucoma

Julie Schaub; Arina Korneva; Elizabeth Cone Cone-Kimball; Mary Ellen Pease; Sarah Quillen; Ian F Pitha; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2001.

ARVO Annual Meeting Abstract June 2020

Changes in Astrocyte Morphology in the Mouse Optic Nerve Head with Experimental Glaucoma

Sarah Quillen; Julie Schaub; Mary Ellen Pease; Elizabeth Cone Cone-Kimball; Arina Korneva; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2003.

ARVO Annual Meeting Abstract June 2020

Regional Mechanical Strains in Mouse Astrocytic Lamina and Peripapillary Sclera after Chronic IOP Elevation

Arina Korneva; Elizabeth Cone Cone-Kimball; Thao D Nguyen; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):996.

ARVO Annual Meeting Abstract July 2018

RHO-kinase-mediated regulation of myofibroblast differentiation in scleral fibroblasts during experimental glaucoma

Ian F Pitha; Ericka Oglesby; Elizabeth Cone-Kimball; Julie Schaub; Mary Pease; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6038.

ARVO Annual Meeting Abstract July 2018

Structural Characterization of Human Lamina Cribrosa and Its Correlation to IOP-induced Strain

Yik Tung Tracy Ling; Ran shi; Dan Midgett; Cathy Nguyen; Elizabeth Cone-Kimball; Mary Pease; Harry A Quigley; Thao D Nguyen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1219.

Articles March 2018

Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP–Glaucoma

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Ian Pitha; Elizabeth C. Kimball; Ericka N. Oglesby; Mary Ellen Pease; Jie Fu; Julie Schaub; Yoo-Chun Kim; Qi Hu; Justin Hanes; Harry A. Quigley
TAGS: cell-derived microparticles, dorzolamide, glaucoma, intraocular pressure, retinal ganglion cells, eye, eyedrops, injections
Trans. Vis. Sci. Tech.. 2018; 7(2):13. https://doi.org/10.1167/tvst.7.2.13

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Lack of regional axon loss in a murine glaucoma model

Julie Schaub; Elizabeth Cone-Kimball; Mary Ellen Pease; Ericka Oglesby; Cathy Nguyen; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2554.

ARVO Annual Meeting Abstract June 2017

Mitochondrial movement and density in mouse ocular explant model after experimental glaucoma

Elizabeth Cone-Kimball; Mary Ellen Pease; Julie Schaub; Ericka Oglesby; Ian Pitha; Cathy Nguyen; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4606.

ARVO Annual Meeting Abstract June 2017

Sustained dorzolamide release prevents axonal and retinal ganglion cell loss in a rat model of IOP-glaucoma

Ian Pitha; Elizabeth Cone-Kimball; Ericka Oglesby; Mary Ellen Pease; Jie Fu; Yoo-Chun Kim; Julie Schaub; Qi Hu; Justin Hanes; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):853.

ARVO Annual Meeting Abstract June 2017

Losartan inhibits myofibroblast transdifferentiation of human scleral fibroblasts

Ericka Oglesby; Julie Schaub; Elizabeth Cone-Kimball; Mary Ellen Pease; Ian Pitha; Harry A Quigley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4604.

ARVO Annual Meeting Abstract June 2017

Quantitative measures of alteration in the astrocytic lamina of mouse optic nerve head with experimental glaucoma

Yik Tung Tracy Ling; Cathy Nguyen; Elizabeth Cone-Kimball; Mary Ellen Pease; Harry A Quigley; Thao D Nguyen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3169.

Glaucoma May 2017

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model

PDF

Julie A. Schaub; Elizabeth C. Kimball; Matthew R. Steinhart; Cathy Nguyen; Mary E. Pease; Ericka N. Oglesby; Joan L. Jefferys; Harry A. Quigley
TAGS: axon, glaucoma, mice, eye, retinal ganglion cells, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2765-2773. https://doi.org/10.1167/iovs.17-21761

Includes: Supplemental Content

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The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

A novel glaucoma model using explanted porcine eyes capable of assessing axonal transport block and lamina cribrosa cellular responses

Effects of topical Rho kinase inhibitor, ripasudil, on murine optic nerve astrocytes in a glaucoma model

Effects of topical ripasudil on response of mouse optic nerve to experimental glaucoma and nerve crush

Comparison of the Biomechanics of the Mouse Astrocytic Lamina Cribrosa Between Glaucoma and Optic Nerve Crush Models

Dissociation enzyme treatment alters strain response of astrocytic lamina in explanted mouse optic nerve head

Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve

The Role of Aquaporins in the Optic Nerve Head Astrocytes in Experimental Glaucoma

Amyloid precursor protein transport block evaluation as a biomarker for experimental mouse glaucoma

Changes in Astrocyte Morphology in the Mouse Optic Nerve Head with Experimental Glaucoma

Regional Mechanical Strains in Mouse Astrocytic Lamina and Peripapillary Sclera after Chronic IOP Elevation

RHO-kinase-mediated regulation of myofibroblast differentiation in scleral fibroblasts during experimental glaucoma

Structural Characterization of Human Lamina Cribrosa and Its Correlation to IOP-induced Strain

Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP–Glaucoma

Lack of regional axon loss in a murine glaucoma model

Mitochondrial movement and density in mouse ocular explant model after experimental glaucoma

Sustained dorzolamide release prevents axonal and retinal ganglion cell loss in a rat model of IOP-glaucoma

Losartan inhibits myofibroblast transdifferentiation of human scleral fibroblasts

Quantitative measures of alteration in the astrocytic lamina of mouse optic nerve head with experimental glaucoma

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model

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