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Retina December 2024

Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

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Yuhui Pang; Chaokun Luo; Qingruo Zhang; Xiongze Zhang; Nanying Liao; Yuying Ji; Lan Mi; Yuhong Gan; Yongyue Su; Feng Wen; Hui Chen
TAGS: anti-vascular endothelial growth factor therapy, diabetes mellitus, diabetic retinopathy, edema, machine learning, multiomics, macula lutea, hypertension, nonproliferative diabetic retinopathy, metabolomics
Trans. Vis. Sci. Tech.. 2024; 13(12):23. https://doi.org/10.1167/tvst.13.12.23

Includes: Supplemental Content

Retina August 2024

Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging

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Xuenan Zhuang; Miaoling Li; Lan Mi; Xiongze Zhang; Jiaxin Pu; Guiqin He; Liang Zhang; Honghua Yu; Liwei Yao; Hui Chen; Yuying Ji; Chengguo Zuo; Yongyue Su; Yuhong Gan; Xinlei Hao; Yining Zhang; Xuelin Chen; Feng Wen
TAGS: anti-vascular endothelial growth factor therapy, exudative age-related macular degeneration, molecule, diagnostic imaging, hypertension, metabolites, metabolomics, multiomics, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):24. https://doi.org/10.1167/iovs.65.10.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

PDLIM1 Suppresses Retinal Neovascularization by Regulating β-catenin Pathway

Xinxiao Gao; Wen Feng; Pinxue Xie

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):835.

Retina May 2024

Diurnal Variation in Choroidal Parameters Among Healthy Subjects Using Wide-Field Swept-Source Optical Coherence Tomography Angiography

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Guiqin He; Xiongze Zhang; Xuenan Zhuang; Yunkao Zeng; Xuelin Chen; Yuhong Gan; Yongyue Su; Yining Zhang; Feng Wen
TAGS: angiogram, circadian rhythms, optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(5):16. https://doi.org/10.1167/tvst.13.5.16

Retina February 2024

A Novel Exploration of the Choroidal Vortex Vein System: Incidence and Characteristics of Posterior Vortex Veins in Healthy Eyes

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Guiqin He; Xiongze Zhang; Xuenan Zhuang; Yunkao Zeng; Yuhong Gan; Yongyue Su; Miaoling Li; Yuying Ji; Lan Mi; Xuelin Chen; Feng Wen
TAGS: eye, incidence
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):21. https://doi.org/10.1167/iovs.65.2.21

Includes: Supplemental Content

Retina August 2023

Choroidal Vein Alterations in Pachychoroid Disease With Choroidal Vascular Hyperpermeability: Evaluated by Wide-Field Indocyanine Green Angiography

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Guiqin He; Xiongze Zhang; Yuhong Gan; Miaoling Li; Xuenan Zhuang; Yunkao Zeng; Yongyue Su; Xuelin Chen; Feng Wen
TAGS: central serous chorioretinopathy, eye, indocyanine green angiography, anastomosis, surgical
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):25. https://doi.org/10.1167/iovs.64.11.25

Retina June 2023

Detection of Choroidal Neovascularization Using Optical Tissue Transparency

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Xiao-Hong Ma; Wen-Yang Feng; Ke Xiao; Zheng Zhong; Peng Fei; Yin Zhao; Xu-Fang Sun
TAGS: body tissue, choroidal neovascularization, optics, transparency, lasers, fluorescent antibody technique, eye
Trans. Vis. Sci. Tech.. 2023; 12(6):10. https://doi.org/10.1167/tvst.12.6.10

Includes: Multimedia, Supplemental Content

Retina November 2020

Identification of NLRP3 Inflammation-Related Gene Promoter Hypomethylation in Diabetic Retinopathy

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Hui Chen; Xiongze Zhang; Nanying Liao; Yuying Ji; Lan Mi; Yuhong Gan; Yongyue Su; Feng Wen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):12. https://doi.org/10.1167/iovs.61.13.12

Includes: Supplemental Content

Retina May 2019

Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography as Precursor Lesions of Polypoidal Choroidal Vasculopathy

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Ling Chen; Xiongze Zhang; Miaoling Li; Nanying Liao; Feng Wen
TAGS: eye, indocyanine green angiography, polypoidal choroidal vasculopathy, spectral domain-optical coherence tomography, pathogenesis, choroid, lipids, color, blinded, multimodal imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2102-2109. https://doi.org/10.1167/iovs.19-26968

Retina October 2018

Drusen and Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography, a Candidate Correlate of Lipid Accumulation

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Ling Chen; Xiongze Zhang; Miaoling Li; Yuhong Gan; Feng Wen
TAGS: drusen, indocyanine green angiography, lipids
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5237-5245. https://doi.org/10.1167/iovs.18-25124

ARVO Annual Meeting Abstract July 2018

A generalizable destabilized domain-based approach to quickly and reversibly control gene therapies in the eye

John D Hulleman; Shyamtanu Datta; Fang Zhang; Wenzhi Feng

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4547.

Retina February 2018

Enhanced Expression of NLRP3 Inflammasome-Related Inflammation in Diabetic Retinopathy

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Hui Chen; Xiongze Zhang; Nanying Liao; Lan Mi; Yuting Peng; Bing Liu; Shaochong Zhang; Feng Wen
TAGS: diabetic retinopathy, inflammation, interleukin-18, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):978-985. https://doi.org/10.1167/iovs.17-22816

Clinical and Epidemiologic Research June 2015

Associations Between Topical Ophthalmic Corticosteroids and Central Serous Chorioretinopathy: A Taiwanese Population-Based Study

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Yuh-Shin Chang; Shih-Feng Weng; Chun Chang; Jhi-Joung Wang; Jiu-Yao Wang; Ren-Long Jan
TAGS: adrenal corticosteroids, central serous chorioretinopathy, eye, glucocorticoids, mineralocorticoids, taiwanese
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):4083-4089. https://doi.org/10.1167/iovs.14-16360

ARVO Annual Meeting Abstract June 2015

Impact of time of day and length of wear on contact lens discomfort

Nancy J Keir; Sruthi Srinivasan; William Ngo; Paul Chamberlain; Wenjuan Feng; Lyndon William Jones; John J McNally

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):6107.

ARVO Annual Meeting Abstract April 2014

REASSESS (REtinal ASSESment Scale) - A clinical grading scale for Inherited Retinal Degenerations

Sharon M Alexander; Catherine Hutchinson; David Simpson; Vittorio Silvestri; Mike Stevenson; Rui Chen; Feng Weng; Silvestri Giuliana

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1392.

ARVO Annual Meeting Abstract March 2012

Regulation of Lens Differentiation by Sumoylation with SUMO1/2/3

David W. Li; Lili Gong; Weike Ji; Mi Deng; Jinping Liu; Peichao Chen; Wen-Feng Hu; Xiaohui Hu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1305.

Genetics October 2011

Association of Genetic Variation on Chromosome 9p21 with Polypoidal Choroidal Vasculopathy and Neovascular Age-Related Macular Degeneration

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Xiongze Zhang; Feng Wen; Chengguo Zuo; Meng Li; Hui Chen; Kunfang Wu
TAGS: 9p21 nucleotide sequence, chromosomes, exudative age-related macular degeneration, genetics, vascular diseases, coronary arteriosclerosis
Invest. Ophthalmol. Vis. Sci.. 2011; 52(11):8063-8067. https://doi.org/10.1167/iovs.11-7820

ARVO Annual Meeting Abstract April 2011

Transcriptional Regulation of PP2A-Aβ Is Mediated by Multiple Transcription Factors

Jiao Liu; Lili Gong; Mi Deng; Wei-Ke Ji; Jia-Han Lv; Shuming Sun; Lan Zhang; Pei-Qiao Chen; Wen-Feng Hu; David W. Li

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2778.

ARVO Annual Meeting Abstract April 2011

The Lens Stem Cells Appear To Be Localized In The Central Epithelium Of The Ocular Lens

Shuming Sun; Long Liu; Xiaoming Zeng; Lan Zhang; Jiao Liu; Pei-Qiao Chen; Wen-Feng Hu; Xiao-Hui Hu; David W. Li

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2787.

Immunology and Microbiology June 2010

The Role of TLR2, TRL3, TRL4, and TRL9 Signaling in the Pathogenesis of Autoimmune Disease in a Retinal Autoimmunity Model

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Jiazhu Fang; Dan Fang; Phyllis B. Silver; Feng Wen; Bing Li; Xiangrong Ren; Qing Lin; Rachel R. Caspi; Shao Bo Su
TAGS: autoimmune diseases, autoimmunity, immunization, mice, pathogenesis, signal transduction, toll-like receptor 2, toll-like receptor 4, antigens, immunologic adjuvants
Invest. Ophthalmol. Vis. Sci.. 2010; 51(6):3092-3099. https://doi.org/10.1167/iovs.09-4754

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Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging

PDLIM1 Suppresses Retinal Neovascularization by Regulating β-catenin Pathway

Diurnal Variation in Choroidal Parameters Among Healthy Subjects Using Wide-Field Swept-Source Optical Coherence Tomography Angiography

A Novel Exploration of the Choroidal Vortex Vein System: Incidence and Characteristics of Posterior Vortex Veins in Healthy Eyes

Choroidal Vein Alterations in Pachychoroid Disease With Choroidal Vascular Hyperpermeability: Evaluated by Wide-Field Indocyanine Green Angiography

Detection of Choroidal Neovascularization Using Optical Tissue Transparency

Identification of NLRP3 Inflammation-Related Gene Promoter Hypomethylation in Diabetic Retinopathy

Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography as Precursor Lesions of Polypoidal Choroidal Vasculopathy

Drusen and Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography, a Candidate Correlate of Lipid Accumulation

A generalizable destabilized domain-based approach to quickly and reversibly control gene therapies in the eye

Enhanced Expression of NLRP3 Inflammasome-Related Inflammation in Diabetic Retinopathy

Associations Between Topical Ophthalmic Corticosteroids and Central Serous Chorioretinopathy: A Taiwanese Population-Based Study

Impact of time of day and length of wear on contact lens discomfort

REASSESS (REtinal ASSESment Scale) - A clinical grading scale for Inherited Retinal Degenerations

Regulation of Lens Differentiation by Sumoylation with SUMO1/2/3

Association of Genetic Variation on Chromosome 9p21 with Polypoidal Choroidal Vasculopathy and Neovascular Age-Related Macular Degeneration

Transcriptional Regulation of PP2A-Aβ Is Mediated by Multiple Transcription Factors

The Lens Stem Cells Appear To Be Localized In The Central Epithelium Of The Ocular Lens

The Role of TLR2, TRL3, TRL4, and TRL9 Signaling in the Pathogenesis of Autoimmune Disease in a Retinal Autoimmunity Model

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