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Retina June 2024

Multicentric Longitudinal Prospective Study in a European Cohort of MYO7A Patients: Disease Course and Implications for Gene Therapy

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Francesco Testa; Ester Carreño; L. Ingeborgh van den Born; Paolo Melillo; Irene Perea-Romero; Valentina Di Iorio; Giulia Risca; Clemente Maria Iodice; Ronald J. E. Pennings; Marianthi Karali; Sandro Banfi; Alberto Auricchio; Stefania Galimberti; Carmen Ayuso; Francesca Simonelli
TAGS: cohort studies, disease progression, european continental ancestry group, gene therapy, prospective studies, usher syndrome, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):25. https://doi.org/10.1167/iovs.65.6.25

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Chorioretinal atrophy after treatment with Voretigene Neparvovec in clinical practice

Michele Della Corte; Paolo Melillo; Clemente Maria Iodice; Valentina Di Iorio; Danila Pisani; Amelia Citro; Settimio Rossi; Marianthi Karali; Francesco Testa; Sandro Banfi; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):910.

ARVO Annual Meeting Abstract June 2024

Role of circulating acylated ghrelin in diabetic retinopathy

Ernesto Marano; Maria Consiglia Trotta; Carlo Gesualdo; Francesco Petrillo; Anca Hermenean; Settimio Rossi; Michele D'Amico; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):873.

ARVO Annual Meeting Abstract June 2024

Multicentric longitudinal prospective study in Usher Syndrome due to MYO7A mutations: disease course and implications for gene therapy

Clemente Maria Iodice; Ester Carreño; L. Ingeborgh van den Born; Paolo Melillo; Irene Perea-Romero; Valentina Di Iorio; Giulia Risca; Ronald J.E. Pennings; Marianthi Karali; Sandro Banfi; Alberto Auricchio; Stefania Galimberti; Francesco Testa; Carmen Ayuso; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2136.

ARVO Annual Meeting Abstract June 2024

Real-world safety and effectiveness of voretigene neparvovec: Year 3 interim results from the PERCEIVE study

M Dominik Fischer; Francesca Simonelli; Isabelle S Audo; Bart Peter Leroy; Line Kessel; Joao Pedro Marques; Mirjana Bjelos; James Bainbridge; Manar Aoun; Rainer Maier; Rehna Khan; Andreas Clemens; Frank G Holz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3290.

ARVO Annual Meeting Abstract June 2024

Cystoid Macular Edema in Patients with Retinitis Pigmentosa and its Genetic Association

Danila Pisani; Marianthi Karali; Valentina Di Iorio; Lorenzo Cantile; Emanuele Madonna; Antonio Niccolò; Raffaella Colucci; Antonella De Benedictis; Paolo Melillo; Francesco Testa; Sandro Banfi; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3116.

ARVO Annual Meeting Abstract June 2024

Early Onset Macular Drusen associated to rare variants in CFH-gene

Luciana Damiano; Marianthi Karali; Clemente Maria Iodice; Danila Pisani; Valentina Di Iorio; Anna Nesti; Paolo Melillo; Francesco Testa; Sandro Banfi; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4436.

ARVO Annual Meeting Abstract June 2024

Predictive factors of treatment response for navigated yellow subthreshold micropulse laser in chronic central serous chorioretinopathy

CLAUDIO IOVINO; Clemente Maria Iodice; Luciana Damiano; Danila Pisani; Settimio Rossi; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6301.

ARVO Annual Meeting Abstract June 2023

Role of 6-tioguanine in a mouse model of diabetic retinopathy

Marina Russo; Carlo Gesualdo; Maria Consiglia Trotta; Caterina Claudia Lepre; Filomena De Nigris; Claudio Bucolo; Michele D'Amico; Francesca Simonelli; Settimio Rossi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):217.

ARVO Annual Meeting Abstract June 2023

Curcuma Longa and Boswellia Serrata Oral Administration in patients with Treatment-Naïve Diabetic Macular Edema

CLAUDIO IOVINO; Valentina Di Iorio; Andrea Attilio Rosolia; Irene Schiavetti; Michele Lanza; Francesco Testa; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2686.

ARVO Annual Meeting Abstract June 2023

Analysis of choriocapillaris vascular density changes in patients with retinitis pigmentosa caused by RPGR gene mutations

Ernesto Marano; Carlo Gesualdo; Antonio Del Giudice; Francesco Guarino; Paolo Melillo; Settimio Rossi; Francesco Testa; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4650.

ARVO Annual Meeting Abstract June 2023

Anatomic and functional retinal changes in female carriers of pathogenic variants in RPGR gene

Valentina Di Iorio; Luciana Damiano; Raffaella Colucci; Antonio Del Giudice; Carlo Gesualdo; Paolo Melillo; Francesco Testa; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4666.

ARVO Annual Meeting Abstract June 2023

Clinical findings in Retinitis Pigmentosa related to CNGB1 variants

Andrea Attilio Rosolia; Valentina Di Iorio; Marianthi Karali; Anna Nesti; Paolo Melillo; Francesco Testa; Sandro Banfi; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4665.

ARVO Annual Meeting Abstract June 2023

Longitudinal natural history study of dominant retinitis pigmentosa due to RHO gene mutations

Clemente Maria Iodice; Valentina Di Iorio; Antonella De Benedictis; Gabriella Esposito; Marianthi Karali; Paolo Melillo; Francesco Testa; Sandro Banfi; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4652.

ARVO Annual Meeting Abstract June 2023

Chromatic pupillometry as an objective outcome to evaluate effects of Voretigene Neparvovec treatment in patients with RPE65 -related inherited retinal dystrophies

Francesco Testa; Paolo Melillo; Valentina Di Iorio; Amelia Citro; Settimio Rossi; MIchele Della Corte; Francesca Simonelli

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5445.

ARVO Annual Meeting Abstract June 2022

Efficacy and safety of sepofarsen, an intravitreal RNA antisense oligonucleotide, for the treatment of CEP290 -associated Leber congenital amaurosis (LCA10): a randomized, double-masked, sham-controlled, Phase 3 study (ILLUMINATE)

Bart Peter Leroy; Katarina Stingl; Isabelle S Audo; Camiel J F Boon; Fernanda Belga O Porto; Michel Michaelides; Helene Dollfus; L. Ingeborgh van den Born; Lyubomyr M Lytvynchuk; Francesca Simonelli; Juliana M F Sallum; Robert K Koenekoop; Elise Heon; Stephen R Russell; Michael Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4536 – F0323.

Articles March 2022

Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study

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Maria Consiglia Trotta; Carlo Gesualdo; Francesco Petrillo; Giancuomo Cavasso; Alberto Della Corte; Giovanbattista D'Amico; Anca Hermenean; Francesca Simonelli; Settimio Rossi
TAGS: biological markers, diabetes mellitus, diabetic retinopathy, hepatorenal syndrome, hrs trial, pilot projects, cytokine, nonproliferative diabetic retinopathy, arginase, chemokines
Trans. Vis. Sci. Tech.. 2022; 11(3):16. https://doi.org/10.1167/tvst.11.3.16

Retina February 2022

RPE65 -Associated Retinopathies in the Italian Population: A Longitudinal Natural History Study

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Francesco Testa; Vittoria Murro; Sabrina Signorini; Leonardo Colombo; Giancarlo Iarossi; Francesco Parmeggiani; Benedetto Falsini; Anna Paola Salvetti; Raffaella Brunetti-Pierri; Giorgia Aprile; Chiara Bertone; Agnese Suppiej; Francesco Romano; Marianthi Karali; Simone Donati; Paolo Melillo; Andrea Sodi; Luciano Quaranta; Luca Rossetti; Luca Buzzonetti; Marzio Chizzolini; Stanislao Rizzo; Giovanni Staurenghi; Sandro Banfi; Claudio Azzolini; Francesca Simonelli
TAGS: italian, rpe65 protein, cohort studies, retinal diseases, natural history, italy
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):13. https://doi.org/10.1167/iovs.63.2.13

Special Issue September 2021

Voretigene Neparvovec Gene Therapy in Clinical Practice: Treatment of the First Two Italian Pediatric Patients

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Francesco Testa; Paolo Melillo; Michele Della Corte; Valentina Di Iorio; Raffaella Brunetti-Pierri; Amelia Citro; Maurizio Ferrara; Marianthi Karali; Rosa Annibale; Sandro Banfi; Settimio Rossi; Francesca Simonelli

Trans. Vis. Sci. Tech.. 2021; 10(10):11. https://doi.org/10.1167/tvst.10.10.11

Retina July 2021

Spectrum of Disease Severity in Nonsyndromic Patients With Mutations in the CEP290 Gene: A Multicentric Longitudinal Study

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Francesco Testa; Andrea Sodi; Sabrina Signorini; Valentina Di Iorio; Vittoria Murro; Raffaella Brunetti-Pierri; Enza Maria Valente; Marianthi Karali; Paolo Melillo; Sandro Banfi; Francesca Simonelli
TAGS: cohort studies, genes, longitudinal studies, mutation, phenotype, severity of illness, pathologic nystagmus, introns, genotype, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):1. https://doi.org/10.1167/iovs.62.9.1

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Multicentric Longitudinal Prospective Study in a European Cohort of MYO7A Patients: Disease Course and Implications for Gene Therapy

Chorioretinal atrophy after treatment with Voretigene Neparvovec in clinical practice

Role of circulating acylated ghrelin in diabetic retinopathy

Multicentric longitudinal prospective study in Usher Syndrome due to MYO7A mutations: disease course and implications for gene therapy

Real-world safety and effectiveness of voretigene neparvovec: Year 3 interim results from the PERCEIVE study

Cystoid Macular Edema in Patients with Retinitis Pigmentosa and its Genetic Association

Early Onset Macular Drusen associated to rare variants in CFH-gene

Predictive factors of treatment response for navigated yellow subthreshold micropulse laser in chronic central serous chorioretinopathy

Role of 6-tioguanine in a mouse model of diabetic retinopathy

Curcuma Longa and Boswellia Serrata Oral Administration in patients with Treatment-Naïve Diabetic Macular Edema

Analysis of choriocapillaris vascular density changes in patients with retinitis pigmentosa caused by RPGR gene mutations

Anatomic and functional retinal changes in female carriers of pathogenic variants in RPGR gene

Clinical findings in Retinitis Pigmentosa related to CNGB1 variants

Longitudinal natural history study of dominant retinitis pigmentosa due to RHO gene mutations

Chromatic pupillometry as an objective outcome to evaluate effects of Voretigene Neparvovec treatment in patients with RPE65 -related inherited retinal dystrophies

Efficacy and safety of sepofarsen, an intravitreal RNA antisense oligonucleotide, for the treatment of CEP290 -associated Leber congenital amaurosis (LCA10): a randomized, double-masked, sham-controlled, Phase 3 study (ILLUMINATE)

Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study

RPE65 -Associated Retinopathies in the Italian Population: A Longitudinal Natural History Study

Voretigene Neparvovec Gene Therapy in Clinical Practice: Treatment of the First Two Italian Pediatric Patients

Spectrum of Disease Severity in Nonsyndromic Patients With Mutations in the CEP290 Gene: A Multicentric Longitudinal Study

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