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Letters to the Editor May 2022

Re: Trivizki et al. Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization

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Maximilian Pfau; Steffen Schmitz-Valckenberg; Frank G. Holz; Monika Fleckenstein
TAGS: atrophy, growth rate, macular neovascularization
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):10. doi: https://doi.org/10.1167/iovs.63.5.10

Articles April 2022

Interviewer Administration Corresponds to Self-Administration of the Vision Impairment in Low Luminance (VILL) Questionnaire

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Jan Henrik Terheyden; Liza Mekschrat; Reglind A. D. Ost; Gamze Bildik; Moritz Berger; Maximilian W. M. Wintergerst; Frank G. Holz; Robert P. Finger
TAGS: luminance, questionnaires, self administration, visual impairment
Trans. Vis. Sci. Tech.. 2022; 11(4):21. doi: https://doi.org/10.1167/tvst.11.4.21

Includes: Supplemental Content

Articles March 2022

Intersession Repeatability of Structural Biomarkers in Early and Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report

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Marlene Saßmannshausen; Sarah Thiele; Charlotte Behning; Maximilian Pfau; Matthias Schmid; Sérgio Leal; Ulrich F. O. Luhmann; Robert P. Finger; Frank G. Holz; Steffen Schmitz-Valckenberg; on behalf of the MACUSTAR Consortium
TAGS: age-related macular degeneration, biological markers, retinal imaging, study report, diagnostic imaging, drusen, eye, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2022; 11(3):27. doi: https://doi.org/10.1167/tvst.11.3.27

Retinal Cell Biology January 2022

Autofluorescent Organelles Within the Retinal Pigment Epithelium in Human Donor Eyes With and Without Age-Related Macular Degeneration

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Katharina Bermond; Leon von der Emde; Ioana-Sandra Tarau; Leonie Bourauel; Rainer Heintzmann; Frank G. Holz; Christine A. Curcio; Kenneth R. Sloan; Thomas Ach
TAGS: age-related macular degeneration, donors, eye, granules, organelles, retinal pigment cell, retinal pigment epithelium, lipofuscin, diagnostic imaging, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):23. doi: https://doi.org/10.1167/iovs.63.1.23

Includes: Multimedia, Supplemental Content

Visual Psychophysics and Physiological Optics July 2021

The Relationship Between Visual Sensitivity and Eccentricity, Cone Density and Outer Segment Length in the Human Foveola

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Niklas Domdei; Jenny L. Reiniger; Frank G. Holz; Wolf M. Harmening
TAGS: retinal cone
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):31. doi: https://doi.org/10.1167/iovs.62.9.31

Articles June 2021

Probabilistic Forecasting of Anti-VEGF Treatment Frequency in Neovascular Age-Related Macular Degeneration

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Maximilian Pfau; Soumya Sahu; Rawan Allozi Rupnow; Kathleen Romond; Desiree Millet; Frank G. Holz; Steffen Schmitz-Valckenberg; Monika Fleckenstein; Jennifer I. Lim; Luis de Sisternes; Theodore Leng; Daniel L. Rubin; Joelle A. Hallak
TAGS: anti-vascular endothelial growth factor therapy, exudative age-related macular degeneration, injections, machine learning
Trans. Vis. Sci. Tech.. 2021; 10(7):30. doi: https://doi.org/10.1167/tvst.10.7.30

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

NIGHT study: natural progression of choroideremia

Byron L Lam; Robert E MacLaren; M. Dominik Fischer; Frank G Holz; Mark E Pennesi; David G Birch; Eeva-Marja Sankila; Isabelleanne Meunier; Kimberly E Stepien; Juliana M.F. Sallum; Cindy Lu; Jiajun Liu; Dan Yoon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):34. doi:

ARVO Annual Meeting Abstract June 2021

Optical Coherence Tomography Signs of Early Atrophy in Age-related Macular Degeneration: Inter-Reader Agreement

Steffen Schmitz-Valckenberg; Zhichao Wu; Maximilian Pfau; Barbara Blodi; Frank G Holz; Petrus Chang; Glenn J Jaffe; Sandra Liakopoulos; Srinivas R Sadda; Giovanni Staurenghi; Robyn H Guymer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1936. doi:

ARVO Annual Meeting Abstract June 2021

Postreceptor Neuronal Degeneration in Pseudoxanthoma Elasticum

Kristina Hess; Kristin Raming; Peter Charbel Issa; Philipp Herrmann; Frank G Holz; Maximilian Pfau

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2181. doi:

ARVO Annual Meeting Abstract June 2021

Psychometric properties of the Vision Impairment in Low Luminance (VILL) questionnaire in age-related macular degeneration in the MACUSTAR study

Jan Henrik Terheyden; Susanne Gunda Pondorfer; Charlotte Behning; Moritz Berger; Donna Rowen; Jill Carlton; Frank G Holz; Thomas Butt; John E. Brazier; Robert Patrick Finger

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3500. doi:

ARVO Annual Meeting Abstract June 2021

Organelle distribution of the human retinal pigment epithelium (RPE) in age-related macular degeneration (AMD)

Leon von der Emde; Katharina Bermond; Iona-Sandra Tarau; Leonie Bourauel; Rainer Heintzmann; Frank G Holz; Christine A Curcio; Kenneth R Sloan; Thomas Ach

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3279. doi:

ARVO Annual Meeting Abstract June 2021

Neovascular age-related macular degeneration (nAMD) treated with intravitreal aflibercept (IVT-AFL) treat-and-extend (T&E): post-hoc analysis of injection intensive (I-I) requirement for patients in the ARIES study

Sebastian Wolf; Frank G Holz; Philip Hykin; Edoardo Midena; Eric H Souied; George Lambrou; Tobias Machewitz; Helmut Allmeier; Paul Mitchell

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):423. doi:

ARVO Annual Meeting Abstract June 2021

Association between visual acuity and intraretinal (IRF) or subretinal (SRF) fluid in patients with neovascular age-related macular degeneration (nAMD) treated with intravitreal aflibercept (IVT-AFL) treat-and-extend (T&E): a post-hoc analysis of the ARIES study

Varun Chaudhary; Frank G Holz; Philip Hykin; Edoardo Midena; Eric H Souied; Sebastian Wolf; Tobias Machewitz; George Lambrou; Paul Mitchell

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):341. doi:

ARVO Annual Meeting Abstract June 2021

Inter-reader repeatability of structural biomarkers in age-related macular degeneration in the multi-center MACUSTAR study

Marlene Sassmannshausen; Maximilian Pfau; Sarah Thiele; Charlotte Behning; Matthias Schmid; Frank G Holz; Steffen Schmitz-Valckenberg

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):276. doi:

ARVO Annual Meeting Abstract June 2021

HAWK and HARRIER 48-week data: potential for treatment interval extension in patients with nAMD disease activity at Week 16

Ramin Tadayoni; Glenn J Jaffe; Frank G Holz; Ursula Schmidt-Erfurth; Kanji Takahashi; Gemmy Chui Ming Cheung; Seenu Hariprasad; Kinfemichael Gedif; Rasmus Olsen; Catherine Best; Peter K Kaiser

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):426. doi:

Articles January 2021

Development of the Vision Impairment in Low Luminance Questionnaire

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Susanne G. Pondorfer; Jan H. Terheyden; Helen Overhoff; Jana Stasch-Bouws; Frank G. Holz; Robert P. Finger
TAGS: luminance, questionnaires, visual impairment, psychometrics
Trans. Vis. Sci. Tech.. 2021; 10(1):5. doi: https://doi.org/10.1167/tvst.10.1.5

Includes: Supplemental Content

Articles October 2020

Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images

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Sarah Thiele; Ben Isselmann; Maximilian Pfau; Frank G. Holz; Steffen Schmitz-Valckenberg; Zhichao Wu; Robyn H. Guymer; Chi D. Luu
TAGS: eye, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2020; 9(11):17. doi: https://doi.org/10.1167/tvst.9.11.17

Retina August 2020

Longitudinal Analysis of Structural and Functional Changes in Presence of Reticular Pseudodrusen Associated With Age-Related Macular Degeneration

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Marlene Sassmannshausen; Maximilian Pfau; Sarah Thiele; Rolf Fimmers; Julia S. Steinberg; Monika Fleckenstein; Frank G. Holz; Steffen Schmitz-Valckenberg
TAGS: age-related macular degeneration, eye, reticular pseudodrusen, retina, follow-up
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):19. doi: https://doi.org/10.1167/iovs.61.10.19

Includes: Supplemental Content

Articles July 2020

Retinal and Choroidal Capillary Perfusion Are Reduced in Hypertensive Crisis Irrespective of Retinopathy

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Jan Henrik Terheyden; Maximilian W. M. Wintergerst; Carmen Pizarro; Maximilian Pfau; Gabrielle N. Turski; Frank G. Holz; Robert P. Finger
TAGS: blood capillaries, eye, hypertensive crisis, perfusion, retinal diseases
Trans. Vis. Sci. Tech.. 2020; 9(8):42. doi: https://doi.org/10.1167/tvst.9.8.42

Includes: Supplemental Content

Articles June 2020

Imaging of Therapeutic Effects of Anti-Vascular Endothelial Growth Factor Inhibitors by Optical Coherence Tomography Angiography in a Rat Model

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Johanna H. Meyer; Janine Marx; Claudine Strack; Frank G. Holz; Steffen Schmitz-Valckenberg
TAGS: aflibercept, angiogram, animal model, choroidal neovascularization, diagnostic imaging, endothelial growth factors, lasers, optical coherence tomography, sodium chloride, laser therapy
Trans. Vis. Sci. Tech.. 2020; 9(7):29. doi: https://doi.org/10.1167/tvst.9.7.29

Includes: Supplemental Content

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Re: Trivizki et al. Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization

Interviewer Administration Corresponds to Self-Administration of the Vision Impairment in Low Luminance (VILL) Questionnaire

Intersession Repeatability of Structural Biomarkers in Early and Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report

Autofluorescent Organelles Within the Retinal Pigment Epithelium in Human Donor Eyes With and Without Age-Related Macular Degeneration

The Relationship Between Visual Sensitivity and Eccentricity, Cone Density and Outer Segment Length in the Human Foveola

Probabilistic Forecasting of Anti-VEGF Treatment Frequency in Neovascular Age-Related Macular Degeneration

NIGHT study: natural progression of choroideremia

Optical Coherence Tomography Signs of Early Atrophy in Age-related Macular Degeneration: Inter-Reader Agreement

Postreceptor Neuronal Degeneration in Pseudoxanthoma Elasticum

Psychometric properties of the Vision Impairment in Low Luminance (VILL) questionnaire in age-related macular degeneration in the MACUSTAR study

Organelle distribution of the human retinal pigment epithelium (RPE) in age-related macular degeneration (AMD)

Neovascular age-related macular degeneration (nAMD) treated with intravitreal aflibercept (IVT-AFL) treat-and-extend (T&E): post-hoc analysis of injection intensive (I-I) requirement for patients in the ARIES study

Association between visual acuity and intraretinal (IRF) or subretinal (SRF) fluid in patients with neovascular age-related macular degeneration (nAMD) treated with intravitreal aflibercept (IVT-AFL) treat-and-extend (T&E): a post-hoc analysis of the ARIES study

Inter-reader repeatability of structural biomarkers in age-related macular degeneration in the multi-center MACUSTAR study

HAWK and HARRIER 48-week data: potential for treatment interval extension in patients with nAMD disease activity at Week 16

Development of the Vision Impairment in Low Luminance Questionnaire

Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images

Longitudinal Analysis of Structural and Functional Changes in Presence of Reticular Pseudodrusen Associated With Age-Related Macular Degeneration

Retinal and Choroidal Capillary Perfusion Are Reduced in Hypertensive Crisis Irrespective of Retinopathy

Imaging of Therapeutic Effects of Anti-Vascular Endothelial Growth Factor Inhibitors by Optical Coherence Tomography Angiography in a Rat Model

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