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Article May 2019

Habitual higher order aberrations affect Landolt but not Vernier acuity

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Jenny L. Reiniger; Anne C. Lobecke; Ramkumar Sabesan; Michael Bach; Frenne Verbakel; John de Brabander; Frank G. Holz; Tos T. J. M. Berendschot; Wolf M. Harmening
TAGS: optics, pupil, visual acuity, eye, quality, image quality, visual thresholds
Journal of Vision. 2019; 19(5):11. doi: 10.1167/19.5.11

Includes: Supplemental Content

Retina April 2019

Dark-Adapted Two-Color Fundus-Controlled Perimetry in Macular Telangiectasia Type 2

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Tjebo F. C. Heeren; Simone Tzaridis; Roberto Bonelli; Maximilian Pfau; Marcus Fruttiger; Mali Okada; Catherine Egan; Peter Charbel Issa; Frank G. Holz
TAGS: color, perimetry, rod photoreceptors, telangiectasis, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1760-1767. doi: 10.1167/iovs.18-25360

Multidisciplinary Ophthalmic Imaging January 2019

Spectrally Resolved Fundus Autofluorescence in ABCA4 -Related Retinopathy

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Chantal Dysli; Philipp L. Müller; Johannes Birtel; Frank G. Holz; Philipp Herrmann
TAGS: color, retinal diseases, diagnostic imaging, fundus autofluorescence imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):274-281. doi: 10.1167/iovs.18-25755

Articles January 2019

Mesopic and Dark-Adapted Two-Color Fundus-Controlled Perimetry in Choroidal Neovascularization Secondary to Age-Related Macular Degeneration

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Leon von der Emde; Maximilian Pfau; Sarah Thiele; Philipp T. Möller; Ruth Hassenrik; Monika Fleckenstein; Frank G. Holz; Steffen Schmitz-Valckenberg
TAGS: color, perimetry, age-related macular degeneration, reliability, rod photoreceptors, retinal cone, choroidal neovascularization
Trans. Vis. Sci. Tech.. 2019; 8(1):7. doi: 10.1167/tvst.8.1.7

Articles October 2018

Comparison of Green Versus Blue Fundus Autofluorescence in ABCA4 -Related Retinopathy

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Philipp L. Müller; Maximilian Pfau; Matthias M. Mauschitz; Philipp T. Möller; Johannes Birtel; Petrus Chang; Martin Gliem; Steffen Schmitz-Valckenberg; Monika Fleckenstein; Frank G. Holz; Philipp Herrmann
TAGS: atrophy, retinal diseases, diagnostic imaging, eye, global assessment of functioning, fundus autofluorescence imaging, shape
Trans. Vis. Sci. Tech.. 2018; 7(5):13. doi: 10.1167/tvst.7.5.13

Includes: Supplemental Content

Special Issue September 2018

Retest Reliability of Mesopic and Dark-Adapted Microperimetry in Patients With Intermediate Age-Related Macular Degeneration and Age-Matched Controls

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Susanne G. Welker; Maximilian Pfau; Manuel Heinemann; Steffen Schmitz-Valckenberg; Frank G. Holz; Robert P. Finger
TAGS: age-related macular degeneration, reliability
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD152-AMD159. doi: 10.1167/iovs.18-23878

Special Issue August 2018

Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study

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Philipp L. Müller; Maximilian Pfau; Philipp T. Möller; Jennifer Nadal; Matthias Schmid; Moritz Lindner; Luis de Sisternes; Heidi Stöhr; Bernhard H. F. Weber; Christine Neuhaus; Philipp Herrmann; Steffen Schmitz-Valckenberg; Frank G. Holz; Monika Fleckenstein
TAGS: angiogram, atrophy, age-related macular degeneration, stargardt's disease, chief complaint, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD122-AMD131. doi: 10.1167/iovs.18-23819

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Phase III studies of brolucizumab versus aflibercept in nAMD: 48-week primary and key secondary outcomes from HAWK/HARRIER

Glenn J Jaffe; Adrian H C Koh; Yuichiro Ogura; Andreas Weichselberger; Frank G. Holz; Pravin U Dugel

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1624. doi:

ARVO Annual Meeting Abstract July 2018

In vivo imaging of therapeutic response in the rat retina by anti-vascular growth factor inhibitors using optical coherence tomography angiography (OCT-A)

Johanna Meyer; Janine Groß; Frank G. Holz; Steffen Schmitz-Valckenberg

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5818. doi:

ARVO Annual Meeting Abstract July 2018

The Natural History of the Progression of Choroideremia (NIGHT) Study: Longitudinal Changes in Visual Acuity over 12 Months

Mark E Pennesi; Byron L Lam; M Dominik Fischer; Eeva-Marja Kaarina Sankila; Frank G. Holz; Robert E MacLaren; David G Birch; Ian M MacDonald; Graeme Black; Carel C B Hoyng; Neil M Bressler; Stephen H. Tsang; Kimberly E Stepien; Michael S Ip; Vedran Pavlovic; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3898. doi:

ARVO Annual Meeting Abstract July 2018

Spatial distribution of preserved autofluorescence in patients with choroideremia

Amir H Hariri; Aniz Girach; Michael S Ip; Byron L Lam; M Dominik Fischer; Eeva-Marja Kaarina Sankila; Mark E Pennesi; Frank G. Holz; David G Birch; Robert E MacLaren; Ian M MacDonald; Carel C B Hoyng; Graeme Black; Neil M Bressler; Stephen H. Tsang; Srinivas R. Sadda

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4991. doi:

ARVO Annual Meeting Abstract July 2018

Natural History of Progression of Choroideremia (NIGHT) Study: Cross-Sectional Analysis of Baseline Characteristics

Byron L Lam; M Dominik Fischer; Mark E Pennesi; Eeva-Marja Kaarina Sankila; Frank G. Holz; Robert E MacLaren; David G Birch; Ian M MacDonald; Carel C B Hoyng; Graeme Black; Neil M Bressler; Stephen H. Tsang; Kimberly E Stepien; Michael S Ip; Vedran Pavlovic; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3899. doi:

ARVO Annual Meeting Abstract July 2018

UVR-B-induced NKR-1 expression in ocular tissues is blocked by spantide I in exposed and partner eye

Janine Groß; Alfred R Wegener; Frank G. Holz; Martin Kronschlaeger; Carl-Ludwig Schoenfeld; Linda Meyer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3036. doi:

ARVO Annual Meeting Abstract July 2018

Multimodal retinal image analysis of de novo geographic atrophy development secondary to age-related macular degeneration

Sarah Thiele; Maximilian Pfau; Jennifer Nadal; Monika Fleckenstein; Matthias Schmid; Frank G. Holz; Steffen Schmitz-Valckenberg

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3221. doi:

Retina March 2018

Structure-Function Analysis in Patients With Intermediate Age-Related Macular Degeneration

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Marlene Saßmannshausen; Julia S. Steinberg; Rolf Fimmers; Maximilian Pfau; Sarah Thiele; Monika Fleckenstein; Frank G. Holz; Steffen Schmitz-Valckenberg
TAGS: drusen, perimetry, diagnostic imaging, eye, age-related macular degeneration, retina, pathophysiology, diagnostic imaging of retina, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1599-1608. doi: 10.1167/iovs.17-22712

Includes: Supplemental Content

Special Issue March 2018

Multimodal Imaging Patterns for Development of Central Atrophy Secondary to Age-Related Macular Degeneration

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Sarah Thiele; Maximilian Pfau; Petra P. Larsen; Monika Fleckenstein; Frank G. Holz; Steffen Schmitz-Valckenberg
TAGS: drusen, atrophy, age-related macular degeneration, multimodal imaging
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD1-AMD11. doi: 10.1167/iovs.17-23315

Special Issue March 2018

Local Progression Kinetics of Geographic Atrophy in Age-Related Macular Degeneration Are Associated With Atrophy Border Morphology

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Moritz Lindner; Sebastian Kosanetzky; Maximilian Pfau; Jennifer Nadal; Lukas A. Gördt; Steffen Schmitz-Valckenberg; Matthias Schmid; Frank G. Holz; Monika Fleckenstein; for the FAM-Study Group
TAGS: atrophy, kinetics, age-related macular degeneration, morphology, language morphology, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD12-AMD18. doi: 10.1167/iovs.17-23203

Includes: Supplemental Content

Retina December 2017

Quantitative Fundus Autofluorescence in Pseudoxanthoma Elasticum

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Martin Gliem; Philipp L. Müller; Johannes Birtel; Myra B. McGuinness; Robert P. Finger; Philipp Herrmann; Doris Hendig; Frank G. Holz; Peter Charbel Issa
TAGS: atrophy, bruch's basal membrane, lipofuscin, pseudoxanthoma elasticum, calcification, fundus autofluorescence imaging
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6159-6165. doi: 10.1167/iovs.17-22007

Clinical and Epidemiologic Research August 2017

The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS)

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Matthias M. Mauschitz; Felix Roth; Frank G. Holz; Monique M. B. Breteler; Robert P. Finger
TAGS: bruch's basal membrane, cataract, cataract surgery, retinal nerve fiber layer, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2804-2809. doi: 10.1167/iovs.17-21675

Retina August 2017

Novel Insights Into the Phenotypical Spectrum of KIF11 -Associated Retinopathy, Including a New Form of Retinal Ciliopathy

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Johannes Birtel; Martin Gliem; Elisabeth Mangold; Lars Tebbe; Isabel Spier; Philipp L. Müller; Frank G. Holz; Christine Neuhaus; Uwe Wolfrum; Hanno J. Bolz; Peter Charbel Issa
TAGS: phenotype, retinal diseases, ciliopathies
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):3950-3959. doi: 10.1167/iovs.17-21679

Includes: Supplemental Content

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Habitual higher order aberrations affect Landolt but not Vernier acuity

Dark-Adapted Two-Color Fundus-Controlled Perimetry in Macular Telangiectasia Type 2

Spectrally Resolved Fundus Autofluorescence in ABCA4 -Related Retinopathy

Mesopic and Dark-Adapted Two-Color Fundus-Controlled Perimetry in Choroidal Neovascularization Secondary to Age-Related Macular Degeneration

Comparison of Green Versus Blue Fundus Autofluorescence in ABCA4 -Related Retinopathy

Retest Reliability of Mesopic and Dark-Adapted Microperimetry in Patients With Intermediate Age-Related Macular Degeneration and Age-Matched Controls

Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study

Phase III studies of brolucizumab versus aflibercept in nAMD: 48-week primary and key secondary outcomes from HAWK/HARRIER

In vivo imaging of therapeutic response in the rat retina by anti-vascular growth factor inhibitors using optical coherence tomography angiography (OCT-A)

The Natural History of the Progression of Choroideremia (NIGHT) Study: Longitudinal Changes in Visual Acuity over 12 Months

Spatial distribution of preserved autofluorescence in patients with choroideremia

Natural History of Progression of Choroideremia (NIGHT) Study: Cross-Sectional Analysis of Baseline Characteristics

UVR-B-induced NKR-1 expression in ocular tissues is blocked by spantide I in exposed and partner eye

Multimodal retinal image analysis of de novo geographic atrophy development secondary to age-related macular degeneration

Structure-Function Analysis in Patients With Intermediate Age-Related Macular Degeneration

Multimodal Imaging Patterns for Development of Central Atrophy Secondary to Age-Related Macular Degeneration

Local Progression Kinetics of Geographic Atrophy in Age-Related Macular Degeneration Are Associated With Atrophy Border Morphology

Quantitative Fundus Autofluorescence in Pseudoxanthoma Elasticum

The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS)

Novel Insights Into the Phenotypical Spectrum of KIF11 -Associated Retinopathy, Including a New Form of Retinal Ciliopathy

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