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Articles February 2021

Multimodal Retinal Imaging and Microperimetry Reveal a Novel Phenotype and Potential Trial End Points in CRB1 -Associated Retinopathies

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Danial Roshandel; Jennifer A. Thompson; Rachael C. Heath Jeffery; Danuta M. Sampson; Enid Chelva; Terri L. McLaren; Tina M. Lamey; John N. De Roach; Shane R. Durkin; Fred K. Chen
TAGS: diagnostic imaging of retina, macular disorders, phenotype, retinal diseases, surrogate endpoints, volume, spectral domain-optical coherence tomography, fenestration
Trans. Vis. Sci. Tech.. 2021; 10(2):38. doi: https://doi.org/10.1167/tvst.10.2.38

Includes: Supplemental Content

Articles October 2020

Retinal Boundary Segmentation in Stargardt Disease Optical Coherence Tomography Images Using Automated Deep Learning

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Jason Kugelman; David Alonso-Caneiro; Yi Chen; Sukanya Arunachalam; Di Huang; Natasha Vallis; Michael J. Collins; Fred K. Chen
TAGS: deep learning, optical coherence tomography, stargardt's disease, training, volume, pixel
Trans. Vis. Sci. Tech.. 2020; 9(11):12. doi: https://doi.org/10.1167/tvst.9.11.12

Includes: Supplemental Content

Articles September 2020

Edge of Scotoma Sensitivity as a Microperimetry Clinical Trial End Point in USH2A Retinopathy

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Jason Charng; Tina M. Lamey; Jennifer A. Thompson; Terri L. McLaren; Mary S. Attia; Ian L. McAllister; Ian J. Constable; David A. Mackey; John N. De Roach; Fred K. Chen
TAGS: eye, retinal diseases, scotoma
Trans. Vis. Sci. Tech.. 2020; 9(10):9. doi: https://doi.org/10.1167/tvst.9.10.9

Includes: Supplemental Content

Articles June 2020

Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds

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Jason Charng; Paul G. Sanfilippo; Mary S. Attia; Monika Dolliver; Sukanya Arunachalam; Avenell L. Chew; Evan N. Wong; David A. Mackey; Fred K. Chen
TAGS: eye, scotoma
Trans. Vis. Sci. Tech.. 2020; 9(7):19. doi: https://doi.org/10.1167/tvst.9.7.19

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Cross-sectional and longitudinal analyses of microperimetry in USH2A -related retinitis pigmentosa

Jason Charng; Tina Lamey; Jen Thompson; Terri Mclaren; Mary Attia; John De Roach; David A Mackey; Fred Kuanfu Chen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3384. doi:

Articles February 2020

RTVue XR AngioVue Optical Coherence Tomography Angiography Software Upgrade Impacts on Retinal Thickness and Vessel Density Measurements

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Danuta M. Sampson; Noha Ali; Alex Au Yong; Rumaanah Jeewa; Saumya Rajgopal; Deepaysh D. C. S. Dutt; Sharaf Mohamed; Shehata Mohamed; Alex Hansen; Moreno Menghini; Fred K. Chen
TAGS: angiogram, optical coherence tomography, software, retina
Trans. Vis. Sci. Tech.. 2020; 9(3):10. doi: https://doi.org/10.1167/tvst.9.3.10

Includes: Supplemental Content

Articles November 2019

A Panel of Circulating MicroRNAs Detects Uveal Melanoma With High Precision

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Mitchell S. Stark; Elin S. Gray; Timothy Isaacs; Fred K. Chen; Michael Millward; Ashleigh McEvoy; Pauline Zaenker; Melanie Ziman; H. Peter Soyer; William J. Glasson; Sunil K. Warrier; Andrew L. Stark; Olivia J. Rolfe; Jane M. Palmer; Nicholas K. Hayward
TAGS: intraocular melanoma, micrornas, precision
Trans. Vis. Sci. Tech.. 2019; 8(6):12. doi: https://doi.org/10.1167/tvst.8.6.12

Includes: Supplemental Content

Articles November 2019

Automatic Detection of Cone Photoreceptors With Fully Convolutional Networks

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Jared Hamwood; David Alonso-Caneiro; Danuta M. Sampson; Michael J. Collins; Fred K. Chen
TAGS: retinal cone, datasets
Trans. Vis. Sci. Tech.. 2019; 8(6):10. doi: https://doi.org/10.1167/tvst.8.6.10

Articles September 2019

Properties of the Impact of Vision Impairment and Night Vision Questionnaires Among People With Intermediate Age-Related Macular Degeneration

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Myra B. McGuinness; Robert P. Finger; Zhichao Wu; Chi D. Luu; Fred K. Chen; Jenifer J. Arnold; Usha Chakravarthy; Wilson J. Heriot; Jim Runciman; Robyn H. Guymer; for the LEAD Study Group
TAGS: age-related macular degeneration, dark adaptation, questionnaires, vision, visual impairment, lead
Trans. Vis. Sci. Tech.. 2019; 8(5):3. doi: https://doi.org/10.1167/tvst.8.5.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Delayed differentiation of retinal organoids derived from a patient with CRB1 -associated retinitis pigmentosa.

Xiao Zhang; Samuel McLenachan; Dan Zhang; Shang-Chih Chen; Sukanya Arunachalam; Jennifer A. Thompson; Terri McLaren; Tina Lamey; John De Roach; Fred Kuanfu Chen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2866. doi:

ARVO Annual Meeting Abstract July 2019

Utilising patient-specific retinal organoids to investigate the role of SNRNP200 variants of unknown significance in severe early onset retinitis pigmentosa

Carla Bernadette Mellough; Mariska Ackerman; Jennifer A Thompson; John De Roach; Terri McLaren; Tina Lamey; Anthony Akkari; Ramesh Ram; Shay Leary; Abha Chopra; Shang-Chih Chen; Dan Zhang; Samuel McLenachan; Fred Kuanfu Chen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2868. doi:

ARVO Annual Meeting Abstract July 2019

Optical coherence tomography derived macular volume loss over 5 years in Stargardt disease

Fred Kuanfu Chen; Sukanya Arunachalam; Natasha Vallis; Di Huang; Yi Chen; Jennifer A. Thompson; Terri McLaren; Tina Lamey; John De Roach; Samuel McLenachan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4521. doi:

ARVO Annual Meeting Abstract July 2019

Phenotype characterization and transcript analysis in RCBTB1 -associated retinopathy

Zhiqin Huang; Samuel McLenachan; Dan Zhang; Jennifer A Thompson; Saumya Shekhar Jamuar; Terri McLaren; Tina Lamey; Enid Chelva; John De Roach; Choi Mun Chan; Fred Kuanfu Chen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6059. doi:

ARVO Annual Meeting Abstract July 2019

Patch-based and fully semantic deep learning methods for automatic choroidal segmentation in OCT images

David Alonso-Caneiro; Jason Kugelman; Scott A Read; Jared Hamwood; Stephen J Vincent; Fred Kuanfu Chen; Michael J Collins

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1507. doi:

ARVO Annual Meeting Abstract July 2019

Phase 2b Study of Brimonidine DDS: Potential Novel Treatment for Geographic Atrophy

William R Freeman; Francesco Bandello; Eric H Souied; Robyn H Guymer; Sunir Garg; Fred Kuanfu Chen; Ryan M Rich; Frank G Holz; Yan Li; Kevin Kerr; Francisco J. Lopez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):971. doi:

Multidisciplinary Ophthalmic Imaging September 2018

Posterior Choroidal Stroma Reduces Accuracy of Automated Segmentation of Outer Choroidal Boundary in Swept Source Optical Coherence Tomography

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Erandi Chandrasekera; Evan N. Wong; Danuta M. Sampson; David Alonso-Caneiro; Fred K. Chen
TAGS: choroid, eye, language morphology, morphology, optical coherence tomography, blood vessel wall
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4404-4412. doi: https://doi.org/10.1167/iovs.18-24665

Includes: Supplemental Content

Articles January 2018

Intrasession Repeatability and Interocular Symmetry of Foveal Avascular Zone and Retinal Vessel Density in OCT Angiography

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Fred K. Chen; Moreno Menghini; Alex Hansen; David A. Mackey; Ian J. Constable; Danuta M. Sampson
TAGS: angiogram, eye, retinal vessels, angiosarcoma associated with lymphedema, ligamentous articular strain technique, lung allocation score
Trans. Vis. Sci. Tech.. 2018; 7(1):6. doi: https://doi.org/10.1167/tvst.7.1.6

Includes: Supplemental Content

Articles December 2017

Agreement in Cone Density Derived from Gaze-Directed Single Images Versus Wide-Field Montage Using Adaptive Optics Flood Illumination Ophthalmoscopy

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Avenell L. Chew; Danuta M. Sampson; Irwin Kashani; Fred K. Chen
TAGS: gaze, retinal cone, optics, ophthalmoscopy, floods, light, lighting, chewing
Trans. Vis. Sci. Tech.. 2017; 6(6):9. doi: https://doi.org/10.1167/tvst.6.6.9

Includes: Supplemental Content

Articles December 2017

Intersession Test–Retest Variability of Microperimetry in Type 2 Macular Telangiectasia

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Evan N. Wong; Jehan D. A. De Soyza; David A. Mackey; Ian J. Constable; Fred K. Chen
TAGS: telangiectasis, eye, scotoma
Trans. Vis. Sci. Tech.. 2017; 6(6):7. doi: https://doi.org/10.1167/tvst.6.6.7

Includes: Supplemental Content

Retina June 2017

Axial Length Variation Impacts on Superficial Retinal Vessel Density and Foveal Avascular Zone Area Measurements Using Optical Coherence Tomography Angiography

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Danuta M. Sampson; Peijun Gong; Di An; Moreno Menghini; Alex Hansen; David A. Mackey; David D. Sampson; Fred K. Chen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3065-3072. doi: https://doi.org/10.1167/iovs.17-21551

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Multimodal Retinal Imaging and Microperimetry Reveal a Novel Phenotype and Potential Trial End Points in CRB1 -Associated Retinopathies

Retinal Boundary Segmentation in Stargardt Disease Optical Coherence Tomography Images Using Automated Deep Learning

Edge of Scotoma Sensitivity as a Microperimetry Clinical Trial End Point in USH2A Retinopathy

Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds

Cross-sectional and longitudinal analyses of microperimetry in USH2A -related retinitis pigmentosa

RTVue XR AngioVue Optical Coherence Tomography Angiography Software Upgrade Impacts on Retinal Thickness and Vessel Density Measurements

A Panel of Circulating MicroRNAs Detects Uveal Melanoma With High Precision

Automatic Detection of Cone Photoreceptors With Fully Convolutional Networks

Properties of the Impact of Vision Impairment and Night Vision Questionnaires Among People With Intermediate Age-Related Macular Degeneration

Delayed differentiation of retinal organoids derived from a patient with CRB1 -associated retinitis pigmentosa.

Utilising patient-specific retinal organoids to investigate the role of SNRNP200 variants of unknown significance in severe early onset retinitis pigmentosa

Optical coherence tomography derived macular volume loss over 5 years in Stargardt disease

Phenotype characterization and transcript analysis in RCBTB1 -associated retinopathy

Patch-based and fully semantic deep learning methods for automatic choroidal segmentation in OCT images

Phase 2b Study of Brimonidine DDS: Potential Novel Treatment for Geographic Atrophy

Posterior Choroidal Stroma Reduces Accuracy of Automated Segmentation of Outer Choroidal Boundary in Swept Source Optical Coherence Tomography

Intrasession Repeatability and Interocular Symmetry of Foveal Avascular Zone and Retinal Vessel Density in OCT Angiography

Agreement in Cone Density Derived from Gaze-Directed Single Images Versus Wide-Field Montage Using Adaptive Optics Flood Illumination Ophthalmoscopy

Intersession Test–Retest Variability of Microperimetry in Type 2 Macular Telangiectasia

Axial Length Variation Impacts on Superficial Retinal Vessel Density and Foveal Avascular Zone Area Measurements Using Optical Coherence Tomography Angiography

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