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ARVO Annual Meeting Abstract June 2024

Genetic model for cell-fate tracking and ablation of CCR2-expressing infiltrating monocytes in retinal degeneration: Implications for inhibition of monocyte infiltration as a therapeutic strategy

Wenxin Ma; Pinghu Liu; Yichao Li; Jingqi Lei; Carl Haugen; Lijin Dong; Haohua Qian; Rafeal Villasmil; Robert N Fariss; Wai Wong; Wei Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1675.

ARVO Annual Meeting Abstract June 2024

Molecular and functional characterization of the Epha10 receptor in the mouse central nervous system

Sophia Isabella Ibargüen; Laura Campello; Jacob Nellissery; Haohua Qian; Anand Swaroop

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4761.

ARVO Annual Meeting Abstract June 2024

Optical coherence tomography reveals distinct retinal layer thickness changes for mouse model of retinal degeneration

Haohua Qian; Yong Zeng; Yichao Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5581.

ARVO Annual Meeting Abstract June 2023

Cobalt causes rapid changes in the photoreceptor outer segment structure in optical coherence tomography images of the rabbit retina.

Ethan D Cohen; Steve Wood; Joseph Hanig; Haohua Qian

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2596.

Retina December 2022

Transducin-Deficient Rod Photoreceptors Evaluated With Optical Coherence Tomography and Oxygen Consumption Rate Energy Biomarkers

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Bruce A. Berkowitz; Robert H. Podolsky; Karen Lins Childers; Robin Roberts; Ryan Katz; Rida Waseem; Brian M. Robbings; Daniel T. Hass; James B. Hurley; Ian R. Sweet; Cole Goodman; Haohua Qian; Bruno Alvisio; Sam Heaps
TAGS: biological markers, mice, mitochondria, rod photoreceptors, transducin, optical coherence tomography, oxygen consumption, retina
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):22. https://doi.org/10.1167/iovs.63.13.22

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2022

Functional Changes Within the Rod Inner Segment Ellipsoid in Wildtype Mice: An Optical Coherence Tomography and Electron Microscopy Study

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Bruce A. Berkowitz; Robert H. Podolsky; Karen Lins Childers; Tom Burgoyne; Giulia De Rossi; Haohua Qian; Robin Roberts; Ryan Katz; Rida Waseem; Cole Goodman
TAGS: mice, mitochondria, optical coherence tomography, rod photoreceptors, shape, signal intensity, embryonic lethal mutation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):8. https://doi.org/10.1167/iovs.63.8.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Cobalt causes a rapid long lasting swelling of neurons in the mouse retina using confocal and optical coherence microscopy.

Ethan D Cohen; Roslyn Brehl; Steven C Wood; Haohua Qian; Joseph Hanig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):984 – F0381.

Retinal Cell Biology November 2020

Rod Photoreceptor Neuroprotection in Dark-Reared Pde6brd10 Mice

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Bruce A. Berkowitz; Robert H. Podolsky; Karen Lins Childers; Sarah L. Roche; Thomas G. Cotter; Emma Graffice; Lamis Harp; Kenan Sinan; Ali M. Berri; Michael Schneider; Haohua Qian; Shasha Gao; Robin Roberts

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):14. https://doi.org/10.1167/iovs.61.13.14

Articles June 2020

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

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Hongman Song; Yong Zeng; Sheik Pran Babu Sardar Pasha; Ronald A. Bush; Camasamudram Vijayasarathy; Haohua Qian; Lisa Wei; Henry E. Wiley; Zhijian Wu; Paul A. Sieving
TAGS: eye, retina, spatial vectors, transfer technique, oryctolagus cuniculus, mice, fibroblast growth factor 2, intravitreal injections
Trans. Vis. Sci. Tech.. 2020; 9(7):28. https://doi.org/10.1167/tvst.9.7.28

ARVO Annual Meeting Abstract June 2020

Expansion of the subretinal space and the hyporeflective band reflect two linked aspects of light-induced OCT responses in the outer retina: pH and metabolic activity

Shasha Gao; Yichao Li; Ethan D Cohen; Gregory Vernon; Sonia Chen; Bruce A Berkowitz; Haohua Qian

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2523.

ARVO Annual Meeting Abstract June 2020

Novel Imaging Biomarkers for Mapping the Impact of Mild Mitochondrial Uncoupling in the Outer Retina In Vivo

Yichao Li; Shasha Gao; Bruce A Berkowitz; Hailey Olds; Collin Richards; Joydip Joy; Tilman Rosales; Robin Roberts; Robert Podolsky; Karen Childers; Brad Hubbard; Patrick Sullivan; Haohua Qian

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2524.

ARVO Annual Meeting Abstract July 2019

Outer Retinal Oxidative Stress Measured In Vivo using QUEnch-assiSTed (QUEST) OCT

Haohua Qian; Robert H Podolsky; Karen M Lins-Childers; Yichao Li; Bruce A Berkowitz

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):184.

ARVO Annual Meeting Abstract July 2019

Effects of the Na-K ATPase blocker digoxin on microglia structure and function in real time in the mouse retina.

Ethan D Cohen; Roslyn J Brehl; Haohua Qian; Lin Xu; Nikita Kedia; Huy Vo; Zhuolin Liu; Katherine Shea; Daniel Hammer; Joseph Hanig

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4015.

Retina April 2019

Outer Retinal Oxidative Stress Measured In Vivo Using QUEnch-assiSTed (QUEST) OCT

PDF

Bruce A. Berkowitz; Robert H. Podolsky; Karen M. Lins-Childers; Yichao Li; Haohua Qian
TAGS: aneurysms-osteoarthritis syndrome, apraxia of speech, diltiazem, mice, oxidative stress, saline solutions
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1566-1570. https://doi.org/10.1167/iovs.18-26164

Retinal Cell Biology December 2018

Mitochondrial Respiration in Outer Retina Contributes to Light-Evoked Increase in Hydration In Vivo

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Bruce A. Berkowitz; Robert H. Podolsky; Haohua Qian; Yichao Li; Ke Jiang; Jacob Nellissery; Anand Swaroop; Robin Roberts
TAGS: diagnostic imaging, magnetic resonance imaging, mice, mitochondria, respiration, retina, water, diffusion magnetic resonance imaging, mice, inbred c57bl, magnetic resonance cholangiography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5957-5964. https://doi.org/10.1167/iovs.18-25682

ARVO Annual Meeting Abstract July 2018

Efficacy of clinical-grade iPSC-RPE cells and patch in rodent and swine models of retinal degeneration

Aaron Rising; Vladimir Khristov; Yichao Li; Maria M Campos; Haohua Qian; Jonathan Stoddard; Arvydas Maminishkis; Juan Amaral; Trevor J McGill; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):546.

Multidisciplinary Ophthalmic Imaging February 2018

Light-Dependent OCT Structure Changes in Photoreceptor Degenerative rd 10 Mouse Retina

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Yichao Li; Yikui Zhang; Sonia Chen; Gregory Vernon; Wai T. Wong; Haohua Qian
TAGS: mice, photoreceptors, retina, dark adaptation, eye, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1084-1094. https://doi.org/10.1167/iovs.17-23011

ARVO Annual Meeting Abstract June 2017

Microglia homeostasis in the adult mouse retina: restoration of microglial distribution, morphology, and function following acute depletion

Yikui Zhang; Lian Zhao; Xu Wang; Wenxin Ma; Adam Lazere; Haohua Qian; Robert N Fariss; Jun Zhang; Mones S Abu-Asab; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):806.

ARVO Annual Meeting Abstract June 2017

Human iPSC-RPE cell transplant in a swine laser-injury model mitigates progressive visual functionality decline.

Aaron Rising; Yichao Li; Vladimir Khristov; Balendu Jha; Haohua Qian; Maria M Campos; Arvydas Maminishkis; Juan Amaral; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1992.

ARVO Annual Meeting Abstract June 2017

Effect of retinal degeneration on light-dependent OCT responses in rd10 mouse

Yichao Li; Sonia Chen; Greg Vernon; Haohua Qian

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4862.

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Genetic model for cell-fate tracking and ablation of CCR2-expressing infiltrating monocytes in retinal degeneration: Implications for inhibition of monocyte infiltration as a therapeutic strategy

Molecular and functional characterization of the Epha10 receptor in the mouse central nervous system

Optical coherence tomography reveals distinct retinal layer thickness changes for mouse model of retinal degeneration

Cobalt causes rapid changes in the photoreceptor outer segment structure in optical coherence tomography images of the rabbit retina.

Transducin-Deficient Rod Photoreceptors Evaluated With Optical Coherence Tomography and Oxygen Consumption Rate Energy Biomarkers

Functional Changes Within the Rod Inner Segment Ellipsoid in Wildtype Mice: An Optical Coherence Tomography and Electron Microscopy Study

Cobalt causes a rapid long lasting swelling of neurons in the mouse retina using confocal and optical coherence microscopy.

Rod Photoreceptor Neuroprotection in Dark-Reared Pde6brd10 Mice

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

Expansion of the subretinal space and the hyporeflective band reflect two linked aspects of light-induced OCT responses in the outer retina: pH and metabolic activity

Novel Imaging Biomarkers for Mapping the Impact of Mild Mitochondrial Uncoupling in the Outer Retina In Vivo

Outer Retinal Oxidative Stress Measured In Vivo using QUEnch-assiSTed (QUEST) OCT

Effects of the Na-K ATPase blocker digoxin on microglia structure and function in real time in the mouse retina.

Outer Retinal Oxidative Stress Measured In Vivo Using QUEnch-assiSTed (QUEST) OCT

Mitochondrial Respiration in Outer Retina Contributes to Light-Evoked Increase in Hydration In Vivo

Efficacy of clinical-grade iPSC-RPE cells and patch in rodent and swine models of retinal degeneration

Light-Dependent OCT Structure Changes in Photoreceptor Degenerative rd 10 Mouse Retina

Microglia homeostasis in the adult mouse retina: restoration of microglial distribution, morphology, and function following acute depletion

Human iPSC-RPE cell transplant in a swine laser-injury model mitigates progressive visual functionality decline.

Effect of retinal degeneration on light-dependent OCT responses in rd10 mouse

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