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Biochemistry and Molecular Biology May 2025

Distinct Transcriptomic Profiles of Cultured Anterior and Posterior Populations of Human Infant Scleral Fibroblasts: Including Dopamine Receptors

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Jiali Guan; Guangliang Hong; Zhong Liu; Yingfeng Zheng; Jiangping He; Dajiang Qin; He Li
TAGS: fibroblasts, sclera, infant, single-cell rna-seq, dopamine receptors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):29. https://doi.org/10.1167/iovs.66.5.29

Includes: Supplemental Content

Retina May 2025

Complement C3/C3aR Signaling Pathway Inhibition Ameliorates Retinal Damage in Experimental Retinal Vein Occlusion

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Yanying Zhao; Zhengwei Ge; Tingting Guo; Hengwei Liu; Yufan Zhou; Juan Chen; Heping Xu; Zhongping Chen
TAGS: complement 3, lasers, mice, retinal vein occlusion, signal pathway, signal transduction pathways, complement system proteins, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):2. https://doi.org/10.1167/iovs.66.5.2

Includes: Supplemental Content

Retina April 2025

Use of SGLT2 Inhibitors Versus DPP-4 Inhibitors and Age-Related Macular Degeneration in Patients WithType 2 Diabetes: A Multinational Cohort Study

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Ssu-Yu Pan; Chien-Hsiang Weng; Shang-Feng Tsai; Hui-Ju Lin; Jun-Fu Lin; Ching-Heng Lin; I-Jong Wang; Chien-Chih Chou
TAGS: age-related macular degeneration, diabetes mellitus, type 2, dipeptidyl-peptidase iv inhibitors, sodium-glucose transporter 2 inhibitors, diabetes mellitus, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):58. https://doi.org/10.1167/iovs.66.4.58

Includes: Supplemental Content

Cornea March 2025

Single-Cell Multiomics Analysis of Early Wound Response Programs in the Mouse Corneal Epithelium

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Zhao-Jing Lu; Jin-Guo Ye; Jing-Ni Li; Jiang-Bo Liang; Ming Zhou; Qiu-Ling Hu; Qi-Kai Zhang; Yu-Heng Lin; Ying-Feng Zheng
TAGS: corneal epithelium, genes, mice, wounds and injuries, chromatin, cornea, wound healing, multiomics
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):9. https://doi.org/10.1167/iovs.66.3.9

Includes: Supplemental Content

Immunology and Microbiology December 2024

Itaconate Ameliorates Experimental Autoimmune Uveitis by Modulating Teff/Treg Cell Imbalance Via the DNAJA1/CDC45 Axis

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Qi Jiang; Zhaohuai Li; Yao Huang; Zhaohao Huang; Junjie Chen; Xiuxing Liu; Chun Zhang; Chenyang Gu; Tianfu Wang; He Li; Yingqi Li; Wenru Su
TAGS: autoimmunity, flow cytometry, imbalance, itaconate, mice, regulatory t-lymphocytes, t-lymphocytes, uveitis, inflammation, th17 cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):23. https://doi.org/10.1167/iovs.65.14.23

Includes: Supplemental Content

Genetics December 2024

Linking Iris Cis -Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics

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Jiaying Li; Yun Chen; Wenbin Wang; Ye Zhang; Guangsong Su; Sean K. Wang; Yuanyuan Zhang; Yilong Yao; Shen Wu; Wange Lu; Kunlin Zhang; Chunyan Qiao; Shuning Li; Hengtong Li; Ching-Yu Cheng; Yuwen Liu; Ningli Wang
TAGS: angle closure glaucoma, iris, pathogenesis, enhancer of transcription, diagnostic imaging, chromatin, alleles, multiomics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):18. https://doi.org/10.1167/iovs.65.14.18

Includes: Supplemental Content

Cornea September 2024

Single-Cell Transcriptomic Analysis Reveals Dynamic Cellular Processes in Corneal Epithelium During Wound Healing in Cynomolgus Monkeys

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Ming Zhou; Zhuo-Xing Shi; Zhong Liu; Shu-Rui Ke; Chao-Yang Wang; Xiao-Lin Liang; Qiu-Ling Hu; Qi-Kai Zhang; Dong-Liang Wang; Li Sun; Yu-Heng Lin; Qi Dai; Ying-Feng Zheng
TAGS: cornea, corneal epithelium, genes, macaca fascicularis, wound healing, epithelium, transcription, genetic, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):43. https://doi.org/10.1167/iovs.65.11.43

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Assessing Visuomotor Abilities in Cerebral Visual Impairment with Eye and Hand Tracking

Lotfi Merabet; Madeleine Heynen; Claire Manley; John Ross Rizzo; Helen Lindner

Journal of Vision. 2024; 24(10):387. https://doi.org/10.1167/jov.24.10.387

Retina July 2024

Optimization-Based Pairwise Interaction Point Process (O-PIPP): A Precise and Universal Retinal Mosaic Modeling Approach

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Liuyuan He; Wenyao Wang; Lei Ma; Tiejun Huang
TAGS: mosaicism
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):39. https://doi.org/10.1167/iovs.65.8.39

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Clinical and imaging characteristics of central serous chorioretinopathy with subfoveal leak

Rajan Alagar; Selina Chang; Arman Zarnegar; Ashika Patil; Niroj Sahoo; Rubble Mangla; Ramesh Venkatesh; Federico Ricardi; Michele Reibaldi; Enrico Borrelli; Lucas Zago Ribeiro; Luiz Henrique Lima; Antonio M B Casella; Dmitrii S Maltsev; Jose Fernandez-Vigo; Jay Chhablani

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4833.

ARVO Annual Meeting Abstract June 2024

Patient reported outcomes of satisfaction by severity of glaucoma

Helen Liu; Jihwan Albert Hwang; Rachel H. Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1894.

ARVO Annual Meeting Abstract June 2024

Association of Myopia with Higher Risk of Incident Visual Impairment in a Multi-ethnic Asian Population: the Singapore Epidemiology of Eye Diseases Study

Faye Yu Ci Ng; Zhi Wei Lim; Miao Li Chee; Hengtong Li; Charumathi Sabanayagam; Ching-Yu Cheng; Yih Chung Tham

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):423.

ARVO Annual Meeting Abstract June 2024

Choroidal vascularity index at baseline and follow-up of active uveitic eyes: a systematic review and meta-analysis

Nicholas Chieh LOH; Valeria Villabona-Martinez; Yuan Heng Lim; Jo Earn Bong; Carlos Cifuentes González; William Rojas-Carabali; Rupesh Vijay Agrawal

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1399.

ARVO Annual Meeting Abstract June 2024

Proliferative diabetic retinopathy and center-involving diabetic macular edema display strong genetic associations with common variants in Asian populations

Renee Liu; Penny Benchek; A Rizza; Ricky Chan; Rehana Khan Khan; Ashley Li; Gayatri Susarla; Hengtong Li; Charumathi Sabanayagam; Ching-Yu Cheng; Kim Brustoski; Rajiv Raman; Lucia Sobrin; Mathavan Sinnakaruppan; Sudha K Iyengar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1800.

ARVO Annual Meeting Abstract June 2024

A novel retinal-derived deep learning marker enhances morbidity and mortality prediction

Ching-Yu Cheng; Tyler Hyungtaek RIM; Hengtong Li; Marco Yu; Cheer Quek Ten; Geunyoung Lee; Qingsheng Peng; Can Can Xue; Zhuoting Zhu; Charumathi Sabanayagam; Tien Y Wong; Yih Chung Tham; Simon Nusinovici

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1506.

ARVO Annual Meeting Abstract June 2024

Monounsaturated fatty acids and the risk of age-related macular degeneration: a Mendelian Randomization Study

Cancan Xue; Hengtong Li; Qiao Fan; Gemmy Cheung; Yih-Chung Tham; Ching-Yu Cheng

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3793.

ARVO Annual Meeting Abstract June 2024

Exploring Meridian Breaks, Choroidal Vascular Density, Vasodilation, and C Thickness as Potential Biomarkers of Disease Activity in Central Serous Chorioretinopathy: A Retrospective Study

Raphaela Masetto Cadide Fuganti; Fernando Campiolo; Ana P M T Oguido; Luiz Henrique Lima; Antonio M B Casella

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4403.

ARVO Annual Meeting Abstract June 2024

SKG0106, an AAV vector delivered intravitreally, for effective, safe and durable treatment of nAMD

Heping Li; Yanqun Shu; Daping Xu; Jay Hou

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5338.

ARVO Annual Meeting Abstract June 2024

Ocular Post-Mortem Analyses with Histopathological and Molecular Assessments in LHON Following AAV2 Gene Therapy

Valerio Carelli; Nancy J. Newman; Leonardo Caporali; Fred Ross-Cisneros; Elisa Boschetti; Valerie Biousse; Lindreth DuBois; Henry Liu; Philippe Ancian; Magali Taiel; Alfredo A Sadun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6083.

ARVO Annual Meeting Abstract June 2024

Characterization of transient intracranial pressure fluctuations

Christina M Nicou; Marshall Holland; Sonia Kuhn Asif; Lisa Hethcox; Chester Calvert; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1210.

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Distinct Transcriptomic Profiles of Cultured Anterior and Posterior Populations of Human Infant Scleral Fibroblasts: Including Dopamine Receptors

Complement C3/C3aR Signaling Pathway Inhibition Ameliorates Retinal Damage in Experimental Retinal Vein Occlusion

Use of SGLT2 Inhibitors Versus DPP-4 Inhibitors and Age-Related Macular Degeneration in Patients WithType 2 Diabetes: A Multinational Cohort Study

Single-Cell Multiomics Analysis of Early Wound Response Programs in the Mouse Corneal Epithelium

Itaconate Ameliorates Experimental Autoimmune Uveitis by Modulating Teff/Treg Cell Imbalance Via the DNAJA1/CDC45 Axis

Linking Iris Cis -Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics

Single-Cell Transcriptomic Analysis Reveals Dynamic Cellular Processes in Corneal Epithelium During Wound Healing in Cynomolgus Monkeys

Assessing Visuomotor Abilities in Cerebral Visual Impairment with Eye and Hand Tracking

Optimization-Based Pairwise Interaction Point Process (O-PIPP): A Precise and Universal Retinal Mosaic Modeling Approach

Clinical and imaging characteristics of central serous chorioretinopathy with subfoveal leak

Patient reported outcomes of satisfaction by severity of glaucoma

Association of Myopia with Higher Risk of Incident Visual Impairment in a Multi-ethnic Asian Population: the Singapore Epidemiology of Eye Diseases Study

Choroidal vascularity index at baseline and follow-up of active uveitic eyes: a systematic review and meta-analysis

Proliferative diabetic retinopathy and center-involving diabetic macular edema display strong genetic associations with common variants in Asian populations

A novel retinal-derived deep learning marker enhances morbidity and mortality prediction

Monounsaturated fatty acids and the risk of age-related macular degeneration: a Mendelian Randomization Study

Exploring Meridian Breaks, Choroidal Vascular Density, Vasodilation, and C Thickness as Potential Biomarkers of Disease Activity in Central Serous Chorioretinopathy: A Retrospective Study

SKG0106, an AAV vector delivered intravitreally, for effective, safe and durable treatment of nAMD

Ocular Post-Mortem Analyses with Histopathological and Molecular Assessments in LHON Following AAV2 Gene Therapy

Characterization of transient intracranial pressure fluctuations

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