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Special Issue September 2017

Metrics and Acquisition Modes for Fixation Stability as a Visual Function Biomarker

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Etienne M. Schönbach; Mohamed A. Ibrahim; Xiangrong Kong; Rupert W. Strauss; Beatriz Muñoz; David G. Birch; Janet S. Sunness; Sheila K. West; Hendrik P. N. Scholl
TAGS: biological markers, vision, visual acuity, eye, stargardt's disease
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO268-BIO276. doi: 10.1167/iovs.17-21710

Retina June 2015

Progression of Vision Loss in Macular Telangiectasia Type 2

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Tjebo F. C. Heeren; Traci Clemons; Hendrik P. N. Scholl; Alan C. Bird; Frank G. Holz; Peter Charbel Issa
TAGS: blindness, scotoma, telangiectasis, eye
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):3905-3912. doi: 10.1167/iovs.15-16915

Includes: Supplemental Content

Articles March 2015

Fixation Stability Measurement Using Two Types of Microperimetry Devices

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Hongting Liu; Millena G. Bittencourt; Raafay Sophie; Yasir J. Sepah; Mostafa Hanout; Zubir Rentiya; Rachel Annam; Hendrik P. N. Scholl; Quan Dong Nguyen
TAGS: sample size, eye, macular disorders, significance
Trans. Vis. Sci. Tech.. 2015; 4(2):3. doi: 10.1167/tvst.4.2.3

Articles September 2014

Assessment of Central Retinal Sensitivity Employing Two Types of Microperimetry Devices

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Hongting Liu; Millena G. Bittencourt; Jiangxia Wang; Raafay Sophie; Rachel Annam; Mohamed A. Ibrahim; Yasir J. Sepah; Ahmadreza Moradi; Hendrik P. N. Scholl; Quan Dong Nguyen
TAGS: mathematics, eye, microbiology procedure, macular disorders, significance, attenuation, luminance, ceiling effect, dynamic range
Trans. Vis. Sci. Tech.. 2014; 3(5):3. doi: 10.1167/tvst.3.5.3

Biochemistry and Molecular Biology April 2012

A Subgroup of Age-Related Macular Degeneration is Associated With Mono-Allelic Sequence Variants in the ABCA4 Gene

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Lars G. Fritsche; Monika Fleckenstein; Britta S. Fiebig; Steffen Schmitz-Valckenberg; Almut Bindewald-Wittich; Claudia N. Keilhauer; Agnes B. Renner; Friederike Mackensen; Andreas Mößner; Daniel Pauleikhoff; Christine Adrion; Ulrich Mansmann; Hendrik P. N. Scholl; Frank G. Holz; Bernhard H. F. Weber
TAGS: alleles, phenotype, atrophy, genes, age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2112-2118. doi: 10.1167/iovs.11-8785

Includes: Supplemental Content

Clinical and Epidemiologic Research June 2011

Incidence of Blindness and Severe Visual Impairment in Germany: Projections for 2030

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Robert P. Finger; Rolf Fimmers; Frank G. Holz; Hendrik P. N. Scholl
TAGS: blindness, germany, visual impairment, incidence
Invest. Ophthalmol. Vis. Sci.. 2011; 52(7):4381-4389. doi: 10.1167/iovs.10-6987

Includes: Supplemental Content

Clinical Trials February 2010

Concordance of Disease Progression in Bilateral Geographic Atrophy Due to AMD

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Monika Fleckenstein; Christine Adrion; Steffen Schmitz-Valckenberg; Arno P. Göbel; Almut Bindewald-Wittich; Hendrik P. N. Scholl; Ulrich Mansmann; Frank G. Holz; for the FAM Study Group
TAGS: atrophy, disease progression, visual acuity, eye, atrophic condition of skin, bland-altman plot
Invest. Ophthalmol. Vis. Sci.. 2010; 51(2):637-642. doi: 10.1167/iovs.09-3547

Retina December 2009

Multimodal Imaging Including Spectral Domain OCT and Confocal Near Infrared Reflectance for Characterization of Outer Retinal Pathology in Pseudoxanthoma Elasticum

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Peter Charbel Issa; Robert P. Finger; Frank G. Holz; Hendrik P. N. Scholl
TAGS: angioid streaks, bruch's basal membrane, pseudoxanthoma elasticum, diagnostic imaging, pathology, peau d'orange surface of breast
Invest. Ophthalmol. Vis. Sci.. 2009; 50(12):5913-5918. doi: 10.1167/iovs.09-3541

Retina August 2009

In Vivo Imaging of Foveal Sparing in Geographic Atrophy Secondary to Age-Related Macular Degeneration

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Steffen Schmitz-Valckenberg; Monika Fleckenstein; Hans-Martin Helb; Peter Charbel Issa; Hendrik P. N. Scholl; Frank G. Holz
TAGS: atrophy, diagnostic imaging, age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2009; 50(8):3915-3921. doi: 10.1167/iovs.08-2484

Retina March 2009

Reading Performance Is Reduced by Parafoveal Scotomas in Patients with Macular Telangiectasia Type 2

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Robert P. Finger; Peter Charbel Issa; Rolf Fimmers; Frank G. Holz; Gary S. Rubin; Hendrik P. N. Scholl
TAGS: reading (activity), scotoma, telangiectasis, eye, parafoveal region
Invest. Ophthalmol. Vis. Sci.. 2009; 50(3):1366-1370. doi: 10.1167/iovs.08-2032

Retina September 2008

High-Resolution Spectral Domain-OCT Imaging in Geographic Atrophy Associated with Age-Related Macular Degeneration

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Monika Fleckenstein; Peter Charbel Issa; Hans-Martin Helb; Steffen Schmitz-Valckenberg; Robert P. Finger; Hendrik P. N. Scholl; Karin U. Loeffler; Frank G. Holz
TAGS: atrophy, diagnostic imaging, eye, age-related macular degeneration, retina, atrophic condition of skin
Invest. Ophthalmol. Vis. Sci.. 2008; 49(9):4137-4144. doi: 10.1167/iovs.08-1967

Retina March 2008

Confocal Blue Reflectance Imaging in Type 2 Idiopathic Macular Telangiectasia

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Peter Charbel Issa; Tos T. J. M. Berendschot; Giovanni Staurenghi; Frank G. Holz; Hendrik P. N. Scholl
TAGS: fluorescein angiography, pigment, telangiectasis, diagnostic imaging, eye, parafoveal region
Invest. Ophthalmol. Vis. Sci.. 2008; 49(3):1172-1177. doi: 10.1167/iovs.07-0636

Retina August 2007

Microperimetric Assessment of Patients with Type 2 Idiopathic Macular Telangiectasia

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Peter Charbel Issa; Hans-Martin Helb; Klaus Rohrschneider; Frank G. Holz; Hendrik P. N. Scholl
TAGS: angiogram, patient evaluation, color, fluorescein angiography, fovea centralis, pigment, scotoma, telangiectasis, visual acuity, eye, parafoveal region
Invest. Ophthalmol. Vis. Sci.. 2007; 48(8):3788-3795. doi: 10.1167/iovs.06-1272

Retina June 2006

Correlation between the Area of Increased Autofluorescence Surrounding Geographic Atrophy and Disease Progression in Patients with AMD

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Steffen Schmitz-Valckenberg; Almut Bindewald-Wittich; Joanna Dolar-Szczasny; Jens Dreyhaupt; Sebastian Wolf; Hendrik P. N. Scholl; Frank G. Holz
TAGS: atrophy, disease progression, eye, atrophic condition of skin, autofluorescence
Invest. Ophthalmol. Vis. Sci.. 2006; 47(6):2648-2654. doi: 10.1167/iovs.05-0892

Retina August 2004

Fundus Autofluorescence in Patients with Leber Congenital Amaurosis

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Hendrik P. N. Scholl; N. H. Victor Chong; Anthony G. Robson; Graham E. Holder; Anthony T. Moore; Alan C. Bird
TAGS: photoreceptors, leber's amaurosis, fundus autofluorescence imaging
Invest. Ophthalmol. Vis. Sci.. 2004; 45(8):2747-2752. doi: 10.1167/iovs.03-1208

Retina July 2004

Localized Retinal Electrophysiological and Fundus Autofluorescence Imaging Abnormalities in Maternal Inherited Diabetes and Deafness

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Caren Bellmann; Magella M. Neveu; Hendrik P. N. Scholl; Chris R. Hogg; Pamela P. Rath; Sharon Jenkins; Alan C. Bird; Graham E. Holder
TAGS: diabetes mellitus, diabetes mellitus, type 2, atrophy, electroretinography, mothers, eye, hearing impairment, fundus autofluorescence imaging
Invest. Ophthalmol. Vis. Sci.. 2004; 45(7):2355-2360. doi: 10.1167/iovs.03-1090

Retina February 2004

Photopic and Scotopic Fine Matrix Mapping of Retinal Areas of Increased Fundus Autofluorescence in Patients with Age-Related Maculopathy

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Hendrik P. N. Scholl; Caren Bellmann; Samantha S. Dandekar; Alan C. Bird; Frederick W. Fitzke
TAGS: drusen, choroidal neovascularization, eye, age-related macular degeneration, fundus autofluorescence imaging
Invest. Ophthalmol. Vis. Sci.. 2004; 45(2):574-583. doi: 10.1167/iovs.03-0495

Research Article March 2003

Cone selective adaptation influences L- and M-cone driven signals in electroretinography and psychophysics, by Kremers, Stepien, Scholl & Saito

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Jan Kremers; Maciej W. Stepien; Hendrik P. N. Scholl; Cézar Saito
TAGS: retinal cone, electroretinography, psychophysics
Journal of Vision. 2003; 3(2):3. doi: 10.1167/3.2.3

Visual Neuroscience April 2002

Alterations of Slow and Fast Rod ERG Signals in Patients with Molecularly Confirmed Stargardt Disease Type 1

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Hendrik P. N. Scholl; Dorothea Besch; Reinhard Vonthein; Bernhard H. F. Weber; Eckart Apfelstedt-Sylla
TAGS: electroretinography, rod photoreceptors, stargardt's disease
Invest. Ophthalmol. Vis. Sci.. 2002; 43(4):1248-1256. doi:

Visual Neuroscience October 2001

Slow and Fast Rod ERG Pathways in Patients with X-Linked Complete Stationary Night Blindness Carrying Mutations in the NYX Gene

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Hendrik P. N. Scholl; Hana Langrová; Carsten M. Pusch; Bernd Wissinger; Eberhart Zrenner; Eckart Apfelstedt-Sylla
TAGS: mutation, electroretinography, genes, night blindness, rod photoreceptors, photopsia
Invest. Ophthalmol. Vis. Sci.. 2001; 42(11):2728-2736. doi:

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Metrics and Acquisition Modes for Fixation Stability as a Visual Function Biomarker

Progression of Vision Loss in Macular Telangiectasia Type 2

Fixation Stability Measurement Using Two Types of Microperimetry Devices

Assessment of Central Retinal Sensitivity Employing Two Types of Microperimetry Devices

A Subgroup of Age-Related Macular Degeneration is Associated With Mono-Allelic Sequence Variants in the ABCA4 Gene

Incidence of Blindness and Severe Visual Impairment in Germany: Projections for 2030

Concordance of Disease Progression in Bilateral Geographic Atrophy Due to AMD

Multimodal Imaging Including Spectral Domain OCT and Confocal Near Infrared Reflectance for Characterization of Outer Retinal Pathology in Pseudoxanthoma Elasticum

In Vivo Imaging of Foveal Sparing in Geographic Atrophy Secondary to Age-Related Macular Degeneration

Reading Performance Is Reduced by Parafoveal Scotomas in Patients with Macular Telangiectasia Type 2

High-Resolution Spectral Domain-OCT Imaging in Geographic Atrophy Associated with Age-Related Macular Degeneration

Confocal Blue Reflectance Imaging in Type 2 Idiopathic Macular Telangiectasia

Microperimetric Assessment of Patients with Type 2 Idiopathic Macular Telangiectasia

Correlation between the Area of Increased Autofluorescence Surrounding Geographic Atrophy and Disease Progression in Patients with AMD

Fundus Autofluorescence in Patients with Leber Congenital Amaurosis

Localized Retinal Electrophysiological and Fundus Autofluorescence Imaging Abnormalities in Maternal Inherited Diabetes and Deafness

Photopic and Scotopic Fine Matrix Mapping of Retinal Areas of Increased Fundus Autofluorescence in Patients with Age-Related Maculopathy

Cone selective adaptation influences L- and M-cone driven signals in electroretinography and psychophysics, by Kremers, Stepien, Scholl & Saito

Alterations of Slow and Fast Rod ERG Signals in Patients with Molecularly Confirmed Stargardt Disease Type 1

Slow and Fast Rod ERG Pathways in Patients with X-Linked Complete Stationary Night Blindness Carrying Mutations in the NYX Gene

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