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Cornea & External Disease August 2024

Multimodal Approach in Dry Eye Disease Combining In Vivo Confocal Microscopy and HLA-DR Expression

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Benjamin Blautain; Ghislaine Rabut; Bénédicte Dupas; Luisa Riancho; Hong Liang; Jade Luzu; Antoine Labbé; Jean-Sébastien Garrigue; Françoise Brignole-Baudouin; Christophe Baudouin; Karima Kessal
TAGS: dry eye syndromes, hla-dr antigens, microscopy, confocal, conjunctiva, signs and symptoms
Trans. Vis. Sci. Tech.. 2024; 13(8):39. https://doi.org/10.1167/tvst.13.8.39

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Identification and Characterization of Novel NLRP3 Inflammasome Inhibitors for the Potential Treatment of Retinal Disease

Mirna Rodriguez; Frank Meng; Michael Bishop; D. Victor Perlroth; Hong Liang; Bernd Jandeleit; Kim Williams

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2208.

ARVO Annual Meeting Abstract June 2024

Development of Anti-inflammatory Bispecific Trap-antibodies

Kiho Song; Fernando Correa; Yimeng Shen; Alice Gerchanovsky; Lili Liu; Jason Lin; Anatolii Purchel; Hong Liang; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4599.

ARVO Annual Meeting Abstract June 2024

An Embryo-Fetal Development Study of Tarcocimab after Intravenous Injection in Rabbits

John Sinclair; Janine Lu; Hong Liang; Elise Lewis; Rachel Babineau; Alan Hoberman; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5100.

ARVO Annual Meeting Abstract June 2024

Ocular and Systemic Toxicity Study of KSI-501 Demonstrates Tolerability after Intravitreal and Intravenous Administration in Cynomolgus Monkeys

Hong Liang; John Sinclair; andrew lickteig; Bradley Saville; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5094.

ARVO Annual Meeting Abstract June 2024

Internalization of antibody biopolymer conjugate via receptor-mediated mechanism

Lili Liu; Fernando Correa; Namrata Prasad; Yimeng Shen; Kiho Song; Michael Ngo; Kim Williams; Hong Liang; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6120.

ARVO Annual Meeting Abstract June 2024

Development of enhanced complement regulators for the treatment of Geographic atrophy

Catherine Cho; Fernando Correa; Yimeng Shen; Kiho Song; Lili Liu; Namrata Prasad; Jason Lin; Anatolii Purchel; Rachel Jacobson; Hong Liang; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6119.

ARVO Annual Meeting Abstract June 2024

Simultaneous Assessment of Vascular Responses and Oxygen Saturation Changes to Hypercapnia in Diabetic Mouse Retinas Using Dual-Color Optical Coherence Tomography

Chao Ren; Marcello Magri Amaral; Sheng Zhang; Aaron Adkins; Senyue Hao; Hongwu Liang; Rithwick Rajagopal; Chao Zhou

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5577.

ARVO Annual Meeting Abstract June 2023

KSI-501 is a novel anti-VEGF and anti-IL-6 bispecific biopolymer conjugate to simultaneously address neovascularization and inflammation in retinal diseases

Jason Lin; Fernando Correa; Namrata Prasad; Lili Liu; Mirna Rodriguez; Michael Ngo; Kim Williams; Janine Lu; Rachel Jacobson; William Ngo; Carrie Lin; Xiaojian Huang; Long Pham; Kiho Song; Hong Liang; Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1153.

ARVO Annual Meeting Abstract June 2023

Development of a modular IL-1 trap and anti-HTRA1 bispecific for the treatment of dry AMD

Kiho Song; Fernando Correa; Yimeng Shen; Lili Liu; Namrata Prasad; Jason Lin; Long Pham; Carrie Su; Carrie Lin; William Ngo; Xiaojian Huang; Hong Liang; Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1152.

ARVO Annual Meeting Abstract June 2023

Development and characterization of an anti-HTRA1 antibody for dry AMD treatment

lili liu; Fernando Correa; Namrata Prasad; Rachel Jacobson; Kiho Song; Jason Lin; Carrie Lin; William Ngo; Xiaojian Huang; Long Pham; Carrie Su; Hong Liang; Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1151.

ARVO Annual Meeting Abstract June 2023

Biological Benefits of KSI-501: Novel Bispecific Anti-Inflammatory and Anti-Angiogenic Therapy for the Treatment of both Retinal Vascular and Inflammatory Diseases

Kim Williams; Mirna Rodriguez; Wolf-Nicolas Fischer; Rachel Jacobson; Michael Ngo; Namrata Prasad; Lili Liu; Janine Lu; Fernando Correa; Victor Perlroth; Hong Liang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2215.

ARVO Annual Meeting Abstract June 2023

Nonclinical Pharmacokinetics, Distribution and Excretion of 125 I-KSI-301 after Intravenous Administration in Rats

Hong Liang; John Sinclair; Elizabeth Spencer; Matthew Parloto; Craig Struble; Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2606.

ARVO Annual Meeting Abstract June 2023

Evaluation of retinal vascular responses to hypercapnia using optical coherence tomography angiography

Marcello Magri Magri Amaral; Yilin Li; Sheng Zhang; Chao Ren; Senyue Hao; Aaron J Adkins; Hongwu Liang; Rithwick Rajagopal; Chao Zhou

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2551.

ARVO Annual Meeting Abstract June 2021

Biophysical Characterization of Antibody Biopolymer Conjugate (ABC) Platform for Improved Therapy of Retinal Vascular Diseases

Fernando Correa; Carrie Su; Long Pham; Namrata Prasad; Chandrani Chakraborty; Janine Lu; Rachel Jacobson; Bernd Jandeleit; Didier Benoit; Xiaojian Huang; Ashwath Jayagopal; Hong Liang; Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):561.

ARVO Annual Meeting Abstract June 2020

Characterization of Antibody Biopolymer Conjugate reveals superior biophysical properties compared to naked antibodies

Carrie Su; Fernando Correa; Hong Liang; Rachel Jacobson; Victor Perlroth; Long Pham

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4237.

Articles November 2019

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases

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Mathieu Robin; Hong Liang; Ghislaine Rabut; Edouard Augstburger; Christophe Baudouin; Antoine Labbé
TAGS: meibomian gland, pathophysiology, hypersensitivity, schirmer tear test procedure, signs and symptoms
Trans. Vis. Sci. Tech.. 2019; 8(6):6. https://doi.org/10.1167/tvst.8.6.6

ARVO Annual Meeting Abstract July 2019

Phase 1 first-in-human study of KSI-301: a novel anti-VEGF antibody biopolymer conjugate with extended durability

Sunil S Patel; Joel Naor; Almas Qudrat; Diana V Do; Desiree Buetelspacher; hong liang; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3670.

ARVO Annual Meeting Abstract July 2019

Development of Novel Bispecific Anti-Inflammatory and Anti-Angiogenic Therapy for the Treatment of both Retinal Vascular and Inflammatory Diseases

Fernando Correa; Rachel Jacobson; Namrata Prasad; William Ngo; Janine Lu; Carrie Su; Xiaojian Huang; hong liang; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5396.

ARVO Annual Meeting Abstract July 2019

Chronic Nonclinical Ocular Toxicity Study of KSI-301 Demonstrates Tolerability after Intravitreal Administration in Cynomolgus Monkeys

John Sinclair; hong liang; zachary antonio; paul miller; avery tolosa; joel naor; leah quarberg; alok sharma; Xiaojian Huang; Janine Lu; William Ngo; dan dang; frances clemo; James N Ver Hoeve; T. Michael Nork; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):126.

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Multimodal Approach in Dry Eye Disease Combining In Vivo Confocal Microscopy and HLA-DR Expression

Identification and Characterization of Novel NLRP3 Inflammasome Inhibitors for the Potential Treatment of Retinal Disease

Development of Anti-inflammatory Bispecific Trap-antibodies

An Embryo-Fetal Development Study of Tarcocimab after Intravenous Injection in Rabbits

Ocular and Systemic Toxicity Study of KSI-501 Demonstrates Tolerability after Intravitreal and Intravenous Administration in Cynomolgus Monkeys

Internalization of antibody biopolymer conjugate via receptor-mediated mechanism

Development of enhanced complement regulators for the treatment of Geographic atrophy

Simultaneous Assessment of Vascular Responses and Oxygen Saturation Changes to Hypercapnia in Diabetic Mouse Retinas Using Dual-Color Optical Coherence Tomography

KSI-501 is a novel anti-VEGF and anti-IL-6 bispecific biopolymer conjugate to simultaneously address neovascularization and inflammation in retinal diseases

Development of a modular IL-1 trap and anti-HTRA1 bispecific for the treatment of dry AMD

Development and characterization of an anti-HTRA1 antibody for dry AMD treatment

Biological Benefits of KSI-501: Novel Bispecific Anti-Inflammatory and Anti-Angiogenic Therapy for the Treatment of both Retinal Vascular and Inflammatory Diseases

Nonclinical Pharmacokinetics, Distribution and Excretion of 125 I-KSI-301 after Intravenous Administration in Rats

Evaluation of retinal vascular responses to hypercapnia using optical coherence tomography angiography

Biophysical Characterization of Antibody Biopolymer Conjugate (ABC) Platform for Improved Therapy of Retinal Vascular Diseases

Characterization of Antibody Biopolymer Conjugate reveals superior biophysical properties compared to naked antibodies

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases

Phase 1 first-in-human study of KSI-301: a novel anti-VEGF antibody biopolymer conjugate with extended durability

Development of Novel Bispecific Anti-Inflammatory and Anti-Angiogenic Therapy for the Treatment of both Retinal Vascular and Inflammatory Diseases

Chronic Nonclinical Ocular Toxicity Study of KSI-301 Demonstrates Tolerability after Intravitreal Administration in Cynomolgus Monkeys

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