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Biochemistry and Molecular Biology May 2025

Regulatory Effects of the Wnt7b/β-Catenin/MMP-2 Signaling Pathway on Scleral Stiffness in Guinea Pigs With Form-Deprivation Myopia

PDF

Binyu Wen; Hangyu Li; Hui Tao; Hong Ren; Bosheng Ma; Mengdi Shi; Shen Chen; Jiaqi Du; Ziyi Cai; Jing Zhang; Dongshi Guan; Zhihong Deng
TAGS: caviidae, collagen, gelatinase a, myopia, sclera, signal pathway, signal transduction pathways
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):19. https://doi.org/10.1167/iovs.66.5.19

Includes: Supplemental Content

Cornea February 2025

Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway

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Chao Wang; Yu-Zhi Li; Huan Guo; Shi-Rui Zhou; Xi Peng; Jia-Song Wang; Hua-Tao Xie; Ming-Chang Zhang
TAGS: lacrimal gland, nlr family, pyrin domain-containing 3 protein, sirt1 gene, melatonin, pathophysiology, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):51. https://doi.org/10.1167/iovs.66.2.51

Includes: Supplemental Content

Retina May 2024

Reduced Retinal Vascular Density and Skeleton Length in Amblyopia

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Wenxin Su; Li Ma; Kexin Li; Yiqun Hu; Yanqing Mao; Wenbin Xie; Xinya Hu; Tao Huang; Junfeng Lv; Mingxuan Wang; Biao Yan; Xue Yao; Xiaohe Yan; Jiayi Zhang
TAGS: amblyopia, vascular density, eye
Trans. Vis. Sci. Tech.. 2024; 13(5):21. https://doi.org/10.1167/tvst.13.5.21

Cornea December 2023

Isolation and Culture of Human Meibomian Gland Ductal Cells

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Xi Peng; Ya-Li Du; Shu-Ting Liu; Hua Chen; Jia-Song Wang; Chao Wang; Hua-Tao Xie; Ming-Chang Zhang
TAGS: body tissue, meibomian gland, patient isolation, rosiglitazone, social isolation, lipids, fluorescent antibody technique
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):29. https://doi.org/10.1167/iovs.64.15.29

ARVO Annual Meeting Abstract June 2023

New insights into endolysosome genesis and trafficking and phagosome maturation in mammalian photoreceptors

Sriganesh Ramachandra Rao; Jesse Slone; Jimmy Vu; Taosheng Huang; Steven Jay Fliesler

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3884.

Biochemistry and Molecular Biology July 2022

Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice

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Wenjing Wu; Yongchao Su; Changxi Hu; Huixin Tao; Ying Jiang; Guandong Zhu; Jiadi Zhu; Ying Zhai; Jia Qu; Xiangtian Zhou; Fei Zhao
TAGS: gelatinase a, hypoxia, mice, myopia, sclera, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):2. https://doi.org/10.1167/iovs.63.8.2

Articles December 2021

Changes in Meibum Lipid Composition With Ocular Demodex Infestation

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Hui Gao; Hua Chen; Hua-Tao Xie; Kang-Kang Xu; Bing-Jie Shi; Yu-Kan Huang
TAGS: demodex infestations, lipids
Trans. Vis. Sci. Tech.. 2021; 10(14):6. https://doi.org/10.1167/tvst.10.14.6

Includes: Supplemental Content

Cornea October 2021

Hyperkeratinization and Proinflammatory Cytokine Expression in Meibomian Glands Induced by Staphylococcus aureus

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Hua Chen; Hui Gao; Hua-Tao Xie; Shu-Ting Liu; Yu-Kan Huang; Ming-Chang Zhang
TAGS: cytokine, meibomian gland, mice, staphylococcus aureus, proteins
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):11. https://doi.org/10.1167/iovs.62.13.11

Cornea February 2021

Hedgehog Signaling Pathway Regulates the Proliferation and Differentiation of Rat Meibomian Gland Epithelial Cells

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Jing-Yu Qu; Yu-Ting Xiao; Ying-Ying Zhang; Hua-Tao Xie; Ming-Chang Zhang
TAGS: epithelial cells, erinaceidae, hedgehog signaling pathway, meibomian gland, regulation, zinc finger protein gli1, molecule, cell proliferation, fluorescent antibody technique
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):33. https://doi.org/10.1167/iovs.62.2.33

Includes: Supplemental Content

Cornea December 2020

A Comparison of Methods for Isolation of Limbal Niche Cells: Maintenance of Limbal Epithelial Stem/Progenitor Cells

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Yu-Ting Xiao; Jing-Yu Qu; Hua-Tao Xie; Ming-Chang Zhang; Xin-Yue Zhao

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):16. https://doi.org/10.1167/iovs.61.14.16

Includes: Multimedia, Supplemental Content

Cornea April 2020

Organotypic Culture of Mouse Meibomian Gland: A Novel Model to Study Meibomian Gland Dysfunction In Vitro

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Kang-Kang Xu; Yu-Kan Huang; Xin Liu; Ming-Chang Zhang; Hua-Tao Xie
TAGS: meibomian gland, meibomian gland dysfunction, mice, lipids
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):30. https://doi.org/10.1167/iovs.61.4.30

Cornea June 2017

Rat Limbal Niche Cells Prevent Epithelial Stem/Progenitor Cells From Differentiation and Proliferation by Inhibiting Notch Signaling Pathway In Vitro

PDF

Jing Li; Szu-Yu Chen; Xin-Yue Zhao; Ming-Chang Zhang; Hua-Tao Xie
TAGS: cornea, epithelium, notch signaling pathway, signal transduction, stem cells, ligands, western blotting
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2968-2976. https://doi.org/10.1167/iovs.16-20642

Includes: Supplemental Content

Genetics July 2015

Prevalence of Mitochondrial ND4 Mutations in 1281 Han Chinese Subjects With Leber's Hereditary Optic Neuropathy

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Pingping Jiang; Min Liang; Juanjuan Zhang; Yinglong Gao; Zheyun He; Han Yu; Fuxin Zhao; Yanchun Ji; Xiaoling Liu; Minglian Zhang; Qun Fu; Yi Tong; Yanhong Sun; Xiangtian Zhou; Taosheng Huang; Jia Qu; Min-Xin Guan
TAGS: chinese people, mutation, optic atrophy, hereditary, leber, proband, mitochondria, dna, mitochondrial, prevalence
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4778-4788. https://doi.org/10.1167/iovs.14-16158

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Anti-Ras Molecule Inactivates Experimental Retinal Neovascularization After Intravitreal Non-Biodegradable VEGF/bFGF Implant in the Rabbit Model

Corinne G Wong; Kathryn Osann; Hung Tao Hsu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1965.

ARVO Annual Meeting Abstract April 2014

Application of stable isotope-assisted metabolomics in neovascular (wet) age-related macular degeneration (AMD)

Ioannis Dimopoulos; Tao Huan; Liang Li; Yves Sauve

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1336.

Articles June 2013

Accelerated In Vitro Degradation of Optically Clear Low β -Sheet Silk Films by Enzyme-Mediated Pretreatment

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Ke Shang; Jelena Rnjak-Kovacina; Yinan Lin; Rebecca S. Hayden; Hu Tao; David L. Kaplan
TAGS: catabolism, enzymes, water, cornea
Trans. Vis. Sci. Tech.. 2013; 2(3):2. https://doi.org/10.1167/tvst.2.3.2

Cornea August 2012

Mesenchymal Stem Cells Derived from Human Limbal Niche Cells

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Gui-Gang Li; Ying-Ting Zhu; Hua-Tao Xie; Szu-Yu Chen; Scheffer C. G. Tseng
TAGS: angiogenesis, fibroblasts, stem cell, mesenchymal, stromal cells, collagenase, epithelial cells, epithelium, stem cells, cornea, pericytes
Invest. Ophthalmol. Vis. Sci.. 2012; 53(9):5686-5697. https://doi.org/10.1167/iovs.12-10300

Includes: Supplemental Content

Cornea June 2012

Angiogenesis Potential of Human Limbal Stromal Niche Cells

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Gui-Gang Li; Szu-Yu Chen; Hua-Tao Xie; Ying-Ting Zhu; Scheffer C. G. Tseng
TAGS: angiogenesis, endothelial cells, epithelium, serial passage, pericytes, zinostatin
Invest. Ophthalmol. Vis. Sci.. 2012; 53(7):3357-3367. https://doi.org/10.1167/iovs.11-9414

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Angiogenesis Progenitors in the Human Limbal Niche

Gui-Gang Li; Szu-Yu Chen; Hua-Tao Xie; Scheffer C. Tseng

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3497.

ARVO Annual Meeting Abstract March 2012

Isolation and Expansion of Human Limbal Stromal Niche Cells

Szu-Yu Chen; Hua-Tao Xie; Gui-Gang` Li

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3499.

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Regulatory Effects of the Wnt7b/β-Catenin/MMP-2 Signaling Pathway on Scleral Stiffness in Guinea Pigs With Form-Deprivation Myopia

Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway

Reduced Retinal Vascular Density and Skeleton Length in Amblyopia

Isolation and Culture of Human Meibomian Gland Ductal Cells

New insights into endolysosome genesis and trafficking and phagosome maturation in mammalian photoreceptors

Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice

Changes in Meibum Lipid Composition With Ocular Demodex Infestation

Hyperkeratinization and Proinflammatory Cytokine Expression in Meibomian Glands Induced by Staphylococcus aureus

Hedgehog Signaling Pathway Regulates the Proliferation and Differentiation of Rat Meibomian Gland Epithelial Cells

A Comparison of Methods for Isolation of Limbal Niche Cells: Maintenance of Limbal Epithelial Stem/Progenitor Cells

Organotypic Culture of Mouse Meibomian Gland: A Novel Model to Study Meibomian Gland Dysfunction In Vitro

Rat Limbal Niche Cells Prevent Epithelial Stem/Progenitor Cells From Differentiation and Proliferation by Inhibiting Notch Signaling Pathway In Vitro

Prevalence of Mitochondrial ND4 Mutations in 1281 Han Chinese Subjects With Leber's Hereditary Optic Neuropathy

Anti-Ras Molecule Inactivates Experimental Retinal Neovascularization After Intravitreal Non-Biodegradable VEGF/bFGF Implant in the Rabbit Model

Application of stable isotope-assisted metabolomics in neovascular (wet) age-related macular degeneration (AMD)

Accelerated In Vitro Degradation of Optically Clear Low β -Sheet Silk Films by Enzyme-Mediated Pretreatment

Mesenchymal Stem Cells Derived from Human Limbal Niche Cells

Angiogenesis Potential of Human Limbal Stromal Niche Cells

Angiogenesis Progenitors in the Human Limbal Niche

Isolation and Expansion of Human Limbal Stromal Niche Cells

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