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Meeting Abstract (8)
Journal Articles (5)

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Investigative Ophthalmology & Visual Science (12)
Translational Vision Science & Technology (1)

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ARVO Annual Meeting Abstract (8)
Retina (4)
Articles (1)

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Retina (5)
Genetics (4)
Eye Anatomy and Disorders (3)
Imaging (2)
Nanotechnology and Regenerative Medicine (2)
Retinal Imaging (2)
Immunology and Microbiology (1)
Low Vision (1)
Translational Research (1)

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eye (3)
injections (3)
cohort studies (2)
gene therapy (2)
primates (2)
surgical procedures, operative (2)
adeno-associated virus (1)
anisotropy (1)
blindness (1)
blister (1)

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Retina October 2024

Optimizing Subretinal Bleb Formation for Visual Streak Involvement in a Porcine Model for Retinal Gene Therapy

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Immanuel P. Seitz; Tobias Peters; Felix Reichel; Andrea Bähr; Hanna Auch; Jan Motlik; Taras Ardan; Jana Juhasova; Yaroslav Nemesh; Stefan Juhás; Nikolai Klymiuk; Manuel Dominik Fischer
TAGS: blister, eye, gene therapy, injection site, injections, suidae, anisotropy
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):41. https://doi.org/10.1167/iovs.65.12.41

ARVO Annual Meeting Abstract June 2024

A new subretinal gene therapy for USH1C is well tolerated in wild type pigs

Peter Kiraly; Matthias Mai; Tobias Peters; Immanuel P Seitz; Taras Ardan; Zdenka Ellederova; Yaroslav Nemesh; Ruslan Nyshchuk; Nikolai Klymiuk; Ashley Winslow; Joshua Klein; Kerstin Nagel-Wolfrum; Uwe Wolfrum; Jan Motlik; M Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5341.

ARVO Annual Meeting Abstract June 2024

Retention rates of subretinal gene therapeutic agents based on AAV serotype 2 and 8 using different drug-delivery materials

Felix Reichel; Peter Kiraly; Immanuel Philipp Seitz; M Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):911.

ARVO Annual Meeting Abstract June 2024

Surgical approach for the implantation of a capsular ring electrode into the posterior chamber

Friederike Charlotte Kortuem; Sebastian Kaltenstadler; Sven Schumayer; Bishesh Sigdel; Immanuel Philipp Seitz; Tobias Peters; Albrecht Rothermel; Volker Bucher; Eberhart Zrenner; Karl-Ulrich Bartz-Schmidt; Torsten Strasser

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2086.

ARVO Annual Meeting Abstract June 2024

Host cell protein impurities are not a relevant driver of gene therapy-associated immune response

Immanuel Philipp Seitz; Eduardo Bocanegra; Felix Reichel; Stylianos Michalakis; Martin Biel; Karl Ulrich Bartz-Schmidt; Tobias Peters; M Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5345.

ARVO Annual Meeting Abstract June 2023

Optimizing Subretinal Bleb Formation in a Porcine Model for Retinal Gene Therapy

Immanuel Philipp Seitz; Tobias Peters; Bähr Andrea; Hannah Auch; Motlik Jan; Taras Ardan; Yaroslav Nemesh; Stefan Juhas; Nikolai Klymiuk; Dominik M Fischer

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):778.

ARVO Annual Meeting Abstract June 2022

Neural plasticity of the human visual system reflects treatment effect in gene therapy for Achromatopsia

Immanuel Philipp Seitz; Michael Erb; Thomas Ethofer; Andriani Rina; Georgios Keliris; M Dominik Fischer; Karl-Ulrich Bartz-Schmidt

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):452.

Articles May 2021

Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates

PDF

Eduardo Rodríguez-Bocanegra; Fabian Wozar; Immanuel P. Seitz; Felix F. L. Reichel; Alex Ochakovski; Kirsten Bucher; Barbara Wilhelm; K. Ulrich Bartz-Schmidt; Tobias Peters; M. Dominik Fischer; for the RD-CURE Consortium
TAGS: adeno-associated virus, eye, gene therapy, injections, primates, retina, spectral domain-optical coherence tomography, surgical procedures, operative, microglia
Trans. Vis. Sci. Tech.. 2021; 10(6):15. https://doi.org/10.1167/tvst.10.6.15

Includes: Supplemental Content

Retina November 2017

Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates

PDF

Immanuel P. Seitz; Stylianos Michalakis; Barbara Wilhelm; Felix F. Reichel; G. Alex Ochakovski; Eberhart Zrenner; Marius Ueffing; Martin Biel; Bernd Wissinger; Karl U. Bartz-Schmidt; Tobias Peters; M. Dominik Fischer; for the RD-CURE Consortium
TAGS: cohort studies, disease vectors, dna, gene transfer techniques, genome, injections, primates, spatial vectors, body tissue, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5792-5801. https://doi.org/10.1167/iovs.17-22473

Includes: Supplemental Content

Retina September 2017

High Symmetry of Visual Acuity and Visual Fields in RPGR -Linked Retinitis Pigmentosa

PDF

Julia-Sophia Bellingrath; G. Alex Ochakovski; Immanuel P. Seitz; Susanne Kohl; Eberhart Zrenner; Nicola Hanig; Holger Prokisch; Bernhard H. Weber; Susan M. Downes; Simon Ramsden; Robert E. MacLaren; M. Dominik Fischer
TAGS: cohort studies, disease progression, electroretinography, eye, mutation, phenotype, retinitis pigmentosa, visual acuity, visual fields, vision
Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4457-4466. https://doi.org/10.1167/iovs.17-22077

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

High symmetry of visual field loss in X-linked retinitis pigmentosa

Julia-Sophia Bellingrath; Immanuel Philip Seitz; Susanne Kohl; Eberhart Zrenner; Nicola Gloeckle; Holger Prokisch; Susan Downes; Simon Ramsden; Robert E MacLaren; Dominik M Fischer

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):132.

ARVO Annual Meeting Abstract September 2016

rAAV8 biodistribution and shedding after subretinal injection in non-human primates

Immanuel Philipp Seitz; M. Dominik Fischer; Stylianos Michalakis; Barbara Wilhelm; Nadine Kahle; Eberhart Zrenner; Marius Ueffing; Karl Ulrich Bartz-Schmidt; Martin Biel; Bernd Wissinger; Tobias Peters

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4025.

Retina July 2015

Reversible Increase of Central Choroidal Thickness During High-Altitude Exposure

PDF

M. Dominik Fischer; Andreas Schatz; Immanuel P. Seitz; Kai Schommer; Karl U. Bartz-Schmidt; Florian Gekeler; Gabriel Willmann
TAGS: choroid, high altitude
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4499-4503. https://doi.org/10.1167/iovs.15-16770

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Online ISSN: 2164-2591

Investigative Ophthalmology & Visual Science
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