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ARVO Annual Meeting Abstract June 2024

Metabolomic Profiles of a High Genetic Risk Score for Exfoliation Syndrome/Glaucoma including LOXL1 Gene Polymorphisms

Namuunaa Juramt; Oana A. Zeleznik; Louis R Pasquale; Janey L Wiggs; Jae H Kang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2171.

ARVO Annual Meeting Abstract June 2024

Machine learning based on prediagnostic metabolomic profiles identifies distinct subtypes of exfoliation glaucoma

Akiko Hanyuda; Oana A. Zeleznik; Yoshihiko Raita; Kazuno Negishi; Louis R Pasquale; Janey L Wiggs; Jae H Kang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):998.

ARVO Annual Meeting Abstract June 2024

Gene-Environment Interaction Between Alcohol Intake and a CACNA1A SNP in Relation to Exfoliation Glaucoma/Glaucoma Suspect

Megan Yu; Hannah H Hwang; Namuunaa Juramt; Akiko Hanyuda; Louis R Pasquale; Janey L Wiggs; Jae H Kang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):OD33.

ARVO Annual Meeting Abstract June 2024

Pre-diagnostic plasma endogenous steroids and the risk of exfoliation glaucoma

Hannah H Hwang; Megan Yu; Namuunaa Juramt; Oana A. Zeleznik; Louis R Pasquale; Janey L Wiggs; Jae H Kang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):OD9.

ARVO Annual Meeting Abstract June 2024

Genetic risk for open angle glaucoma subtypes is associated with specific visual field defect classes

Sayuri Sekimitsu; Sophie Smith; Yan Zhao; Mohammad Eslami; Mengyu Wang; Tobias Elze; Ayellet Segre; Jae H Kang; Joni Tururen; Aarno Palotie; Joel Raemoe; Janey L Wiggs; Nazlee Zebardast

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1015.

ARVO Annual Meeting Abstract June 2024

Dual-Level Pattern Tree for Visual Field Characterization in Glaucoma Improves Predicting Progression and Polygenic Risk Score

Luo Song; Lucy Q Shen; Louis R Pasquale; Michael V Boland; Sarah Wellik; Carlos Gustavo De Moraes; Jonathan S. Myers; Tobias Elze; Nazlee Zebardast; David S Friedman; Jae H Kang; Mengyu Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6477.

ARVO Annual Meeting Abstract June 2024

Female Reproductive Factors and Risk of Exfoliation Glaucoma/Glaucoma Suspect

Jae H Kang; Megan Yu; Hannah H Hwang; Namuunaa Juramt; Louis R Pasquale; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4615.

ARVO Annual Meeting Abstract June 2024

The relation between leukocyte telomere length and glaucoma traits in the UK Biobank

Timing Liu; Jae H Kang; Kelsey Vernon Stuart; Robert Luben; Paul J Foster; Peng Tee Khaw; Louis R Pasquale; Anthony P Khawaja; Rachel H. Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4063.

Clinical and Epidemiologic Research August 2023

Metabolite and Lipid Biomarkers Associated With Intraocular Pressure and Inner Retinal Morphology: 1 H NMR Spectroscopy Results From the UK Biobank

PDF

Louis R. Pasquale; Anthony P. Khawaja; Janey L. Wiggs; Jihye Kim; Pirro Hysi; Tobias Elze; Jessica Lasky-Su; Jae H. Kang; Oana Zeleznik; for the UK Biobank Eye and Vision Consortium
TAGS: biobanks, biological markers, intraocular pressure, metabolites, lipids, spectrum analysis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):11. https://doi.org/10.1167/iovs.64.11.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

The association of physical activity with glaucoma and related traits in the UK Biobank

Kian Madjedi; Kelsey Vernon Stuart; Sharon Chua; Pradeep Y Ramulu; Alasdair Warwick; Robert Luben; Zihan Sun; Mark Chia; Hughes Aschard; Janey L Wiggs; Jae H Kang; Louis R Pasquale; Paul Foster; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2904.

ARVO Annual Meeting Abstract June 2023

The clinical utility of a glaucoma polygenic risk score in four European-ancestry cohorts

Victor Anthony de Vries; Akiko Hanyuda; Joëlle Vergroesen; Ron Do; David S Friedman; Peter Kraft; Yuyang Luo; Jessica Tran; Sze H Wong; Nazlee Zebardast; Caroline C W Klaver; Janey L Wiggs; Ayellet V. Segre; Jae H Kang; Wishal Ramdas; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):99.

ARVO Annual Meeting Abstract June 2023

Hypertension and CACNA1A locus in relation to exfoliation glaucoma/glaucoma suspect

Jae H Kang; Louis R Pasquale; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2907.

Glaucoma February 2023

Genetic Associations Between Smoking- and Glaucoma-Related Traits

PDF

Jessica H. Tran; Kelsey V. Stuart; Victor de Vries; Joëlle E. Vergroesen; Clara C. Cousins; Pirro G. Hysi; Ron Do; Ghislain Rocheleau; Jae H. Kang; Janey L. Wiggs; Stuart MacGregor; Anthony P. Khawaja; David A. Mackey; Caroline C. W. Klaver; Wishal D. Ramdas; Louis R. Pasquale; for the UK Biobank Eye and Vision Consortium, and for the International Glaucoma Genetics Consortium
TAGS: genetics, glaucoma, smoking
Trans. Vis. Sci. Tech.. 2023; 12(2):20. https://doi.org/10.1167/tvst.12.2.20

Includes: Supplemental Content

Glaucoma August 2022

Prediagnostic Plasma Metabolomics and the Risk of Exfoliation Glaucoma

PDF

Jae H. Kang; Oana Zeleznik; Lisa Frueh; Jessica Lasky-Su; A. Heather Eliassen; Clary Clish; Bernard A. Rosner; Louis R. Pasquale; Janey L. Wiggs
TAGS: exfoliation syndrome, metabolites, plasma, metabolomics
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):15. https://doi.org/10.1167/iovs.63.9.15

Includes: Supplemental Content

Glaucoma July 2022

Cohort Study of Race/Ethnicity and Incident Primary Open-Angle Glaucoma Characterized by Autonomously Determined Visual Field Loss Patterns

PDF

Jae H. Kang; Mengyu Wang; Lisa Frueh; Bernard Rosner; Janey L. Wiggs; Tobias Elze; Louis R. Pasquale
TAGS: ethnic group, eye, glaucoma, open-angle glaucoma, cohort studies, blindness, visual field defects
Trans. Vis. Sci. Tech.. 2022; 11(7):21. https://doi.org/10.1167/tvst.11.7.21

Includes: Supplemental Content

Clinical and Epidemiologic Research May 2022

Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank

PDF

Jihye Kim; Marianne T. Kennedy Neary; Hugues Aschard; Mathew M. Palakkamanil; Ron Do; Janey L. Wiggs; Anthony P. Khawaja; Louis R. Pasquale; Jae H. Kang; for the International Glaucoma Genetics Consortium (IGGC), UK Biobank Eye and Vision Consortium, and Modifiable Risk Factors for Glaucoma Collaboration
TAGS: biobanks, glaucoma, intraocular pressure, statins
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):31. https://doi.org/10.1167/iovs.63.5.31

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Louis R Pasquale; Jae H Kang; Bernard Rosner; Janey L Wiggs; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3499.

ARVO Annual Meeting Abstract June 2021

Association of patient race and Hispanic ethnicity with age and severity of glaucomatous vision loss at first visit

Qingying Jin; Omar Halawa; Nazlee Zebardast; Louis Pasquale; Jae H Kang; Alice Carlyle Lorch; Lucia Sobrin; Joan W Miller; Yangjiani Li; Mohammad Eslami; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3536.

ARVO Annual Meeting Abstract June 2021

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Christian James Pompoco; Chase Paulson; Samuel C. Taylor; Brian Craig Stagg; Robert Ritch; Jae H Kang; Janey L Wiggs; Louis R Pasquale; Karen Curtin; Barbara M Wirostko

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):71.

ARVO Annual Meeting Abstract June 2020

Association of coffee, tea, and caffeine consumption with intraocular pressure and interaction with genetic risk: findings from the UK Biobank

Jihye Kim; Hugues Aschard; Jae H. Kang; Marleen AH Lentjes; Janey Wiggs; Anthony Khawaja; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):52.

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Metabolomic Profiles of a High Genetic Risk Score for Exfoliation Syndrome/Glaucoma including LOXL1 Gene Polymorphisms

Machine learning based on prediagnostic metabolomic profiles identifies distinct subtypes of exfoliation glaucoma

Gene-Environment Interaction Between Alcohol Intake and a CACNA1A SNP in Relation to Exfoliation Glaucoma/Glaucoma Suspect

Pre-diagnostic plasma endogenous steroids and the risk of exfoliation glaucoma

Genetic risk for open angle glaucoma subtypes is associated with specific visual field defect classes

Dual-Level Pattern Tree for Visual Field Characterization in Glaucoma Improves Predicting Progression and Polygenic Risk Score

Female Reproductive Factors and Risk of Exfoliation Glaucoma/Glaucoma Suspect

The relation between leukocyte telomere length and glaucoma traits in the UK Biobank

Metabolite and Lipid Biomarkers Associated With Intraocular Pressure and Inner Retinal Morphology: 1 H NMR Spectroscopy Results From the UK Biobank

The association of physical activity with glaucoma and related traits in the UK Biobank

The clinical utility of a glaucoma polygenic risk score in four European-ancestry cohorts

Hypertension and CACNA1A locus in relation to exfoliation glaucoma/glaucoma suspect

Genetic Associations Between Smoking- and Glaucoma-Related Traits

Prediagnostic Plasma Metabolomics and the Risk of Exfoliation Glaucoma

Cohort Study of Race/Ethnicity and Incident Primary Open-Angle Glaucoma Characterized by Autonomously Determined Visual Field Loss Patterns

Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Association of patient race and Hispanic ethnicity with age and severity of glaucomatous vision loss at first visit

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Association of coffee, tea, and caffeine consumption with intraocular pressure and interaction with genetic risk: findings from the UK Biobank

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