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Meeting Abstract (6)
Journal Articles (4)

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Investigative Ophthalmology & Visual Science (7)
Translational Vision Science & Technology (3)

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ARVO Annual Meeting Abstract (6)
Articles (2)
Glaucoma (1)
Methods (1)

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Eye Anatomy and Disorders (4)
Glaucoma (4)
Translational Research (3)
Retina (2)
Pharmacology (1)

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eye (4)
glaucoma (3)
intraocular pressure (2)
ocular hypertension (2)
optic disk (2)
retina (2)
retinal ganglion cells (2)
blood flow velocity (1)
brimonidine (1)
brinzolamide ophthalmic suspension (1)

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ARVO Annual Meeting Abstract June 2024

Homocysteine elevation in glaucoma reveals dysfunctional one-carbon metabolism as a target for neuroprotection

James R Tribble; Vickie Hoi Ying Wong; Kelsey V Stuart; Glyn Chidlow; Alan Nicol; Carola Rutigliani; Tim J Enz; Anh Hoang; Pei Ying Lee; Emma Lardner; Gustav Stålhammar; Christine Nguyen; Robert James Casson; Anthony P Khawaja; Bang V Bui; Pete Williams

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):673.

Glaucoma November 2023

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

PDF

Simon T. Gustavsson; Tim J. Enz; James R. Tribble; Mattias Nilsson; Anna Lindqvist; Christina Lindén; Anna Hagström; Carola Rutigliani; Emma Lardner; Gustav Stålhammar; Pete A. Williams; Gauti Jóhannesson
TAGS: glaucoma, niacinamide, ocular hypertension, retinal vasculature, vasculature, vascular flow, eye, optic disk
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):34. https://doi.org/10.1167/iovs.64.14.34

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

NMNAT2 is a druggable target for neuroprotection in glaucoma

Pete Williams; James R Tribble; Melissa Jöe; Andrea Brancale; Carmine Varricchio; Michael Coleman; Jon Gilley; Andrea Loreto; Craig Wheelock; Gauti Johannesson

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1904.

ARVO Annual Meeting Abstract June 2023

Development of neuroprotective small molecular drugs targeting NMNAT2

Melissa Jöe; James R Tribble; Carmine Varricchio; Andrea Brancale; Gauti Johannesson; Craig Wheelock; Pete Williams

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2574.

ARVO Annual Meeting Abstract June 2022

Targeting NMNAT2 for neuroprotection in glaucoma

Pete A Williams; James R Tribble; Melissa Jöe; Andrea Brancale; Carmine Varricchio; Michael Coleman; Jonathan Gilley; Andrea Loreto; Craig Wheelock; Gauti Johannesson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1134.

ARVO Annual Meeting Abstract June 2022

Valproic acid reduces resident neuroinflammation and provides neuroprotection following retinal ganglion cell axotomy

James R Tribble; Elizabeth Kastanaki; A. Bersan Uslular; Carola Rutigliani; Tim J Enz; Pete A Williams

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1613 – A0436.

Articles February 2022

Comparative Assessment of Retinal Blood Flow Velocity Changes Following Brimonidine and Brinzolamide Administration Using Retinal Function Imaging

PDF

Tim J. Enz; Mario Bittner; James R. Tribble; Pete A. Williams; Michael A. Thiel; Martin K. Schmid; Lucas M. Bachmann; Frank Bochmann
TAGS: blood flow velocity, brimonidine, brinzolamide ophthalmic suspension, diagnostic imaging, intraocular pressure, eye
Trans. Vis. Sci. Tech.. 2022; 11(2):1. https://doi.org/10.1167/tvst.11.2.1

Includes: Supplemental Content

Methods January 2021

Retinal Ganglion Cell Degeneration in a Rat Magnetic Bead Model of Ocular Hypertensive Glaucoma

PDF

James R. Tribble; Amin Otmani; Eirini Kokkali; Emma Lardner; James E. Morgan; Pete A. Williams
TAGS: eye, glaucoma, ocular hypertension, retinal ganglion cells, tissue degeneration, optic disk, intraocular pressure, retina, optic nerve
Trans. Vis. Sci. Tech.. 2021; 10(1):21. https://doi.org/10.1167/tvst.10.1.21

Articles January 2021

When Is a Control Not a Control? Reactive Microglia Occur Throughout the Control Contralateral Pathway of Retinal Ganglion Cell Projections in Experimental Glaucoma

PDF

James R. Tribble; Eirini Kokkali; Amin Otmani; Flavia Plastino; Emma Lardner; Rupali Vohra; Miriam Kolko; Helder André; James E. Morgan; Pete A. Williams
TAGS: eye, glaucoma, microglia, retinal ganglion cells, retina, monocytes
Trans. Vis. Sci. Tech.. 2021; 10(1):22. https://doi.org/10.1167/tvst.10.1.22

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

A novel classification system for rat RGCs in retinal degeneration

James R Tribble; Paulina Samsel; Stephen D Cross; Frank Sengpiel; James E Morgan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2389.

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