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Retina March 2025

Genome-Wide Association Study to Identify Genetic Variants Associated With Diabetic Maculopathy

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Rajya L. Gurung; Charvi Nangia; Tengda Cai; Liesel M. FitzGerald; Bennet J. McComish; Ebony Liu; Georgia Kaidonis; Bronwyn Ridge; Alex W. Hewitt; Brendan Vote; Nitin Verma; Jamie E. Craig; Colin N. A. Palmer; Kathryn P. Burdon; Weihua Meng
TAGS: cohort studies, diabetes mellitus, genetics, genome-wide association study, macular disorders, meta-analysis, single nucleotide polymorphism, genotype determination, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):55. https://doi.org/10.1167/iovs.66.3.55

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

A metabolome-wide analysis of Intraocular pressure suggests neuroinflammatory mechanisms as possible mechanisms involved in glaucoma

Pirro G Hysi; Ajda Pristavec; Anthony P Khawaja; Jospeh Bastasic; David A Mackey; Janey L Wiggs; Jamie E Craig; Louis R Pasquale; Christopher J Hammond; Marie-Hélène Roy-Gagnon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):997.

ARVO Annual Meeting Abstract June 2024

Polygenic risk is associated with differential treatment response to SLT and medical therapy in treatment-naive glaucoma

Jamie E Craig; Antonia Kolovos; Thi Thi Nguyen; Joshua Schmidt; Stuart L Graham; Alex W Hewitt; Owen Siggs; Stuart MacGregor; Mark Hassall

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1012.

ARVO Annual Meeting Abstract June 2024

Sleep Apnoea Syndrome Correlated with Progression of Normal Tension Glaucoma

Ella Claire Berry; Henry Marshall; Mark Hassall; Antonia Kolovos; Joshua Schmidt; Sean Mullany; Stewart Lake; Anna Galanopoulos; John Landers; Paul Healey; Stuart L Graham; Alex W Hewitt; Stuart MacGregor; Robert Casson; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2766.

ARVO Annual Meeting Abstract June 2024

An intronic tandem repeat expansion in TMCO1 is associated with open angle glaucoma severity

Owen Siggs; Shannon Ji; Joshua Schmidt; Yves Fontaine; David Dimasi; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2168.

ARVO Annual Meeting Abstract June 2024

Exploring the pathogenicity of THBS1 variants in glaucoma

Haojie Fu; Amy E Birsner; Maria Socorro M. Torno; Cynthia V. Verzosa; Faye R. Levina; Manolito R. Reyes; Stuart Tompson; Kristina Whisenhunt; Edward Ryan Collantes; Terri L Young; Owen Siggs; Jamie E Craig; Janey L Wiggs; Robert J D'Amato

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4233.

Glaucoma June 2024

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

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Abadh K. Chaurasia; Stuart MacGregor; Jamie E. Craig; David A. Mackey; Alex W. Hewitt
TAGS: datasets, glaucoma, optic disk, optic nerve disorders, deep learning, training
Trans. Vis. Sci. Tech.. 2024; 13(6):1. https://doi.org/10.1167/tvst.13.6.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

CNIH4 variants are associated with pigment dispersion syndrome in humans and pigment abnormalities in zebrafish

Shi Song Rong; Anna Larson; John Simmons Borchert; Mark Simcoe; Nicole Weisschuh; Christopher J Hammond; Pirro G Hysi; Robert Ritch; Emmanuelle Souzeau; Jamie E Craig; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4358.

Clinical and Epidemiologic Research March 2023

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

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Ella C. Berry; Henry N. Marshall; Sean Mullany; Santiago Diaz Torres; Joshua Schmidt; Daniel Thomson; Lachlan S. W. Knight; Georgina L. Hollitt; Ayub Qassim; Bronwyn Ridge; Angela Schulz; Mark M. Hassall; Thi Thi Nguyen; Stewart Lake; Richard A. Mills; Ashish Agar; Anna Galanopoulos; John Landers; Paul R. Healey; Stuart L. Graham; Alex W. Hewitt; Stuart MacGregor; Robert J. Casson; Owen M. Siggs; Jamie E. Craig
TAGS: cohort studies, physical activity, biobanks
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):11. https://doi.org/10.1167/iovs.64.3.11

Includes: Supplemental Content

Glaucoma October 2022

Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals

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Georgina L. Hollitt; Owen M. Siggs; Bronwyn Ridge; Miriam C. Keane; David A. Mackey; Stuart MacGregor; Alex W. Hewitt; Jamie E. Craig; Emmanuelle Souzeau
TAGS: genetic risk, glaucoma, attitude
Trans. Vis. Sci. Tech.. 2022; 11(10):38. https://doi.org/10.1167/tvst.11.10.38

Includes: Supplemental Content

Retina July 2022

The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

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Kathleen I. C. Dyer; Paul G. Sanfilippo; Seyhan Yazar; Jamie E. Craig; Alex W. Hewitt; John P. Newnham; David A. Mackey; Samantha S. Y. Lee
TAGS: cohort studies, fetal growth, retinal nerve fiber layer, young adult, pregnancy, birth weight, fetus
Trans. Vis. Sci. Tech.. 2022; 11(7):8. https://doi.org/10.1167/tvst.11.7.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Quality of life in children and adults with childhood glaucoma: An interview study

Lachlan Knight; Bronwyn Ridge; Sandra E Staffieri; Jamie E Craig; Mallika Prem Senthil; Emmanuelle Souzeau

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1823.

ARVO Annual Meeting Abstract June 2022

The APOE E4 allele is associated with faster rates of mGCIPL thinning in the PROGRESSA cohort

Sean Mullany; Henry Marshall; Emmanuelle Souzeau; Mark Hassall; Ashish Agar; Anna Galanopoulos; John Landers; Paul Mitchell; Paul Healey; Stuart L Graham; Alex W Hewitt; Stuart MacGregor; Puya Gharahkhani; Robert Casson; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1658 – A0153.

ARVO Annual Meeting Abstract June 2022

Greater physical activity is associated with neuroretinal thinning in glaucomatous and normative cohorts

Ella Claire Berry; Henry Marshall; Sean Mullany; Santiago Diaz Torres; Joshua Schmidt; Daniel Thomson; Mark Hassall; Stewart R Lake; Richard A Mills; John Landers; Stuart MacGregor; Robert Casson; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3490.

ARVO Annual Meeting Abstract June 2022

High polygenic risk is associated with earlier treatment initiation and escalation in glaucoma suspects

Henry Marshall; Xikun Han; Sean Mullany; Georgie Hollitt; Ella Claire Berry; Lachlan Knight; Richard A Mills; John Landers; Paul Healey; Alex W Hewitt; Stuart L Graham; Robert Casson; Stuart MacGregor; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4018 – A0360.

ARVO Annual Meeting Abstract June 2022

Genetic biomarkers predicting response to anti-vascular endothelial growth factor injections in diabetic macular edema, a pilot study

Rajya L gurung; Liesel M FitzGerald; Bennet J McComish; ebony lui; Jamie E Craig; Nitin Verma; Alex W Hewitt; Brendan JT Vote; Kathryn P Burdon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3852.

Glaucoma March 2022

RNA Sequencing of Lens Capsular Epithelium Implicates Novel Pathways in Pseudoexfoliation Syndrome

PDF

Sean Mullany; Henry Marshall; Tiger Zhou; Daniel Thomson; Joshua M. Schmidt; Ayub Qassim; Lachlan S. W. Knight; Georgina Hollitt; Ella C. Berry; Thi Nguyen; Minh-Son To; David Dimasi; Abraham Kuot; Joshua Dubowsky; Rhys Fogarty; Michelle Sun; Luke Chehade; Shilpa Kuruvilla; Devaraj Supramaniam; James Breen; Shiwani Sharma; John Landers; Stewart Lake; Richard A. Mills; Mark M. Hassall; Weng O. Chan; Sonja Klebe; Emmanuelle Souzeau; Owen M. Siggs; Jamie E. Craig
TAGS: genes, lens, crystalline, epithelium, exfoliation syndrome, sequence analysis, rna
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):26. https://doi.org/10.1167/iovs.63.3.26

Includes: Supplemental Content

Lens September 2021

Genotype, Age, Genetic Background, and Sex Influence Epha2 -Related Cataract Development in Mice

PDF

Alpana Dave; Jamie E. Craig; Mohammad Alamein; Karina Skrzypiec; Justin Beltz; Annalise Pfaff; Kathryn P. Burdon; Nuran Ercal; Robb U. de Iongh; Shiwani Sharma
TAGS: cataract, genetic background, genotype, mice, lens (device), lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):3. https://doi.org/10.1167/iovs.62.12.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Childhood and Early-Onset Glaucoma Classification and Genetic Profile in a Large Australasian Disease Registry

Lachlan Knight; Jonathan B Ruddle; Deepa A Taranath; Ivan Goldberg; James EH Smith; Glen Gole; Mark Y Chiang; Sean Mullany; James E Elder; Andrea L Vincent; Sandra Staffieri; David A Mackey; Susie Luu; Owen M Siggs; Emmanuelle Souzeau; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1515.

ARVO Annual Meeting Abstract June 2021

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Stuart MacGregor; Xikun Han; Puya Gharahkhani; Maciej Trzaskowski; Jamie E Craig; Alex W Hewitt; David A Mackey; Janey L Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1512.

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Genome-Wide Association Study to Identify Genetic Variants Associated With Diabetic Maculopathy

A metabolome-wide analysis of Intraocular pressure suggests neuroinflammatory mechanisms as possible mechanisms involved in glaucoma

Polygenic risk is associated with differential treatment response to SLT and medical therapy in treatment-naive glaucoma

Sleep Apnoea Syndrome Correlated with Progression of Normal Tension Glaucoma

An intronic tandem repeat expansion in TMCO1 is associated with open angle glaucoma severity

Exploring the pathogenicity of THBS1 variants in glaucoma

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

CNIH4 variants are associated with pigment dispersion syndrome in humans and pigment abnormalities in zebrafish

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals

The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

Quality of life in children and adults with childhood glaucoma: An interview study

The APOE E4 allele is associated with faster rates of mGCIPL thinning in the PROGRESSA cohort

Greater physical activity is associated with neuroretinal thinning in glaucomatous and normative cohorts

High polygenic risk is associated with earlier treatment initiation and escalation in glaucoma suspects

Genetic biomarkers predicting response to anti-vascular endothelial growth factor injections in diabetic macular edema, a pilot study

RNA Sequencing of Lens Capsular Epithelium Implicates Novel Pathways in Pseudoexfoliation Syndrome

Genotype, Age, Genetic Background, and Sex Influence Epha2 -Related Cataract Development in Mice

Childhood and Early-Onset Glaucoma Classification and Genetic Profile in a Large Australasian Disease Registry

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

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