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Biochemistry and Molecular Biology September 2024

Metabolic Phenotyping of Healthy and Diseased Human RPE Cells

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Saira Rizwan; Beverly Toothman; Bo Li; Abbi L. Engel; Rayne R. Lim; Sheldon Niernberger; Jinyu Lu; Cloe Ratliff; Yinxiao Xiang; Mark Eminhizer; Jennifer R. Chao; Jianhai Du
TAGS: glutamine, nutrients, phenotype determination, retinal pigment cell, sugars, induced pluripotent stem cells, amino acids
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):5. https://doi.org/10.1167/iovs.65.11.5

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics August 2024

Multimodal High-Resolution Imaging in Retinitis Pigmentosa: A Comparison Between Optoretinography, Cone Density, and Visual Sensitivity

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Benjamin J. Wendel; Vimal Prabhu Pandiyan; Teng Liu; Xiaoyun Jiang; Ayoub Lassoued; Emily Slezak; Sierra Schleufer; Palash Bharadwaj; William S. Tuten; Debarshi Mustafi; Jennifer R. Chao; Ramkumar Sabesan
TAGS: retinal cone, retinitis pigmentosa, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):45. https://doi.org/10.1167/iovs.65.10.45

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Media nutrient composition alters RPE metabolism

Rayne Lim; Yekai Wang; Emily Zhao; Sheldon Niernberger; Jianhai Du; Jennifer R Chao

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):192.

ARVO Annual Meeting Abstract June 2024

Assessment of structure and function in retinitis pigmentosa (RP) patients using coarse-scale optoretinography (CoORG)

Teng Liu; Vimal Prabhu Pandiyan; Ben Wendel; Jennifer Huey; Debarshi Mustafi; Jennifer R Chao; Ramkumar Sabesan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3905.

ARVO Annual Meeting Abstract June 2024

Targeted long-read genome sequencing provides comprehensive genetic diagnosis of inherited retinal diseases

Debarshi Mustafi; Kenji Nakamichi; Jennifer Huey; Jennifer R Chao; Russell N Van Gelder

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4240.

Retinal Cell Biology April 2024

CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration

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Rayne R. Lim; Sharlene Shirali; Jessica Rowlan; Abbi L. Engel; Marcos Nazario,, Jr.; Kelie Gonzalez; Aspen Tong; Jay Neitz; Maureen Neitz; Jennifer R. Chao
TAGS: complement system proteins, macular degeneration, retinal pigment cell, haploinsufficiency, proteins, induced pluripotent stem cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):43. https://doi.org/10.1167/iovs.65.4.43

Includes: Supplemental Content

Optica Fall Vision Meeting Abstract December 2023

Poster Session II: Can a drug for liver disease be used to treat Age-Related Macular Degeneration?

Kriti Pandey; Daniel T Hass; Rayne R Lim; Noah Horton; Jennifer R Chao; James B Hurley
TAGS: age-related macular degeneration, liver diseases, posters
Journal of Vision. 2023; 23(15):67. https://doi.org/10.1167/jov.23.15.67

ARVO Annual Meeting Abstract June 2023

Identification of phased variants in inherited retinal disease patients using targeted long-read sequencing

Debarshi Mustafi; Kenji nakamichi; Russell N Van Gelder; Jennifer R Chao

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2797.

ARVO Annual Meeting Abstract June 2023

Cone outer segment length does not explain optoretinography-derived measures of cone dysfunction in retinitis pigmentosa

Ben Wendel; Teng Liu; Vimal Prabhu Pandiyan; Emily Slezak; Debarshi Mustafi; Jennifer R Chao; Ramkumar Sabesan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3354.

ARVO Annual Meeting Abstract June 2023

Nutrient environments influence retinal pigment epithelium phenotype and metabolic profile.

Rayne Lim; YeKai Wang; Marcos Nazario; Aspen-Marie S Tong; Jianhai Du; Jennifer R Chao

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3192.

ARVO Annual Meeting Abstract June 2022

The diversity of genetic testing platforms for inherited retinal diseases

Debarshi Mustafi; Jennifer R Chao

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):135 – A0315.

ARVO Annual Meeting Abstract June 2022

Complement dysregulation in an iPSC-RPE model with CFH/FHL-1 haploinsufficiency.

Rayne Lim; Sharlene Shirali; Jessica Rowlan; Abbi Engel; Marcos Nazario; Jianhai Du; Maureen Neitz; Jay Neitz; Jennifer R Chao

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1473.

ARVO Annual Meeting Abstract June 2022

Multimodal high-resolution imaging of retinal function in Retinitis Pigmentosa

Ben J Wendel; Vimal Prabhu Pandiyan; Xiaoyun Jiang; Ayoub Lassoued; Emily Slezak; William Scott Tuten; Debarshi Mustafi; Jennifer R Chao; Ramkumar Sabesan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2686.

ARVO Annual Meeting Abstract June 2021

RPE utilizes proline to enhance nutrient availability to the retina

Siyan Zhu; Abbi L Engel; Yekai Wang; Rong Xu; Jennifer R Chao; Jianhai Du

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2231.

ARVO Annual Meeting Abstract June 2021

Crispr/Cas9 correction of the TIMP3 S204C mutation in Sorsby fundus dystrophy iPSC-derived RPE

Abbi Engel; Rayne Lim; Keli Gonzalez; Jennifer R Chao

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2990.

ARVO Annual Meeting Abstract June 2021

A novel CFH mutation affects FHL-1 expression and metabolism in EOMD patient derived iPSC-RPE.

Rayne Ruiyi Lim; Abbi Engel; Jessica Rowlan; Yekai Wang; Kelie Gonzalez; Sharlene Shirali; Jay Neitz; Maureen Neitz; Jianhai Du; Jennifer R Chao

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3112.

ARVO Annual Meeting Abstract June 2020

Quantitative Assessment of Choriocapillaris in Patients with Diabetic Retinopathy: A Swept-Source Optical Coherence Tomography Angiography Study

Yining Dai; Hao Zhou; Qinqin Zhang; Zhongdi Chu; Jennifer R Chao; Kasra A. Rezaei; Ruikang K Wang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2725.

Multidisciplinary Ophthalmic Imaging March 2020

Microvascular Changes in the Choriocapillaris of Diabetic Patients Without Retinopathy Investigated by Swept-Source OCT Angiography

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Yining Dai; Hao Zhou; Zhongdi Chu; Qinqin Zhang; Jennifer R. Chao; Kasra A. Rezaei; Ruikang K. Wang
TAGS: angiogram, diabetes mellitus, diagnostic imaging, retinal diseases, eye, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):50. https://doi.org/10.1167/iovs.61.3.50

ARVO Annual Meeting Abstract July 2019

S-cone function in Blue Cone Monochromacy

Jennifer R Chao; Xiaoyun Jiang; James A Kuchenbecker; Anna-Lisa Doebley; Maureen Neitz; Jay Neitz; Ramkumar Sabesan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):585.

ARVO Annual Meeting Abstract July 2019

Evaluation of gene therapy via intravitreal injection for disorders associated with loss of expression or function of L/M cone opsin

adam crain; James A Kuchenbecker; Jessica S Rowlan; Jennifer R Chao; Jay Neitz; Maureen Neitz

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1309.

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Metabolic Phenotyping of Healthy and Diseased Human RPE Cells

Multimodal High-Resolution Imaging in Retinitis Pigmentosa: A Comparison Between Optoretinography, Cone Density, and Visual Sensitivity

Media nutrient composition alters RPE metabolism

Assessment of structure and function in retinitis pigmentosa (RP) patients using coarse-scale optoretinography (CoORG)

Targeted long-read genome sequencing provides comprehensive genetic diagnosis of inherited retinal diseases

CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration

Poster Session II: Can a drug for liver disease be used to treat Age-Related Macular Degeneration?

Identification of phased variants in inherited retinal disease patients using targeted long-read sequencing

Cone outer segment length does not explain optoretinography-derived measures of cone dysfunction in retinitis pigmentosa

Nutrient environments influence retinal pigment epithelium phenotype and metabolic profile.

The diversity of genetic testing platforms for inherited retinal diseases

Complement dysregulation in an iPSC-RPE model with CFH/FHL-1 haploinsufficiency.

Multimodal high-resolution imaging of retinal function in Retinitis Pigmentosa

RPE utilizes proline to enhance nutrient availability to the retina

Crispr/Cas9 correction of the TIMP3 S204C mutation in Sorsby fundus dystrophy iPSC-derived RPE

A novel CFH mutation affects FHL-1 expression and metabolism in EOMD patient derived iPSC-RPE.

Quantitative Assessment of Choriocapillaris in Patients with Diabetic Retinopathy: A Swept-Source Optical Coherence Tomography Angiography Study

Microvascular Changes in the Choriocapillaris of Diabetic Patients Without Retinopathy Investigated by Swept-Source OCT Angiography

S-cone function in Blue Cone Monochromacy

Evaluation of gene therapy via intravitreal injection for disorders associated with loss of expression or function of L/M cone opsin

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