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Public Health February 2025

Associations Between Diabetic Retinopathy and Frailty: Insights From the National Health and Nutrition Examination Survey and Mendelian Randomization

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Jianqi Chen; Xuhao Chen; Xu Cao; Xiaohua Zhuo; Yuwen Wen; Guitong Ye; Yuan Zhang; Jinan Zhan; Hongmei Tan; Yingting Zhu; Yehong Zhuo
TAGS: frailty, national health and nutrition examination survey, diabetic retinopathy, mendelian randomization analysis
Trans. Vis. Sci. Tech.. 2025; 14(2):2. https://doi.org/10.1167/tvst.14.2.2

Includes: Supplemental Content

Retinal Cell Biology January 2025

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

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Qi Liu; Ling-Xiao Xia; Wan-Zhao Yi; Ya-Ni Wu; Shuo-Shuo Gu; Jian-Ying Chen; Ting-Ting Liu; Ying-Hui Lu; Yu-Hong Cui; Jing Meng; Hong-Wei Pan
TAGS: cyclin d1, endothelial cells, proto-oncogene proteins c-akt, retinal neovascularization, cell cycle, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):66. https://doi.org/10.1167/iovs.66.1.66

Includes: Supplemental Content

Retina November 2024

Midperipheral Microvascular Defects and Their Associations With Vitreoretinal Abnormalities in Early-Stage Familial Exudative Vitreoretinopathy

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Juan Zhang; Lu Ruan; Chen Jiang; Qian Yang; Qing Chang; Xin Huang
TAGS: familial exudative vitreoretinopathies
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):4. https://doi.org/10.1167/iovs.65.13.4

Includes: Supplemental Content

Retina September 2024

Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Parameters and Their Associated Factors in Cynomolgus Macaques

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Yuan Zhang; Guitong Ye; Kezhe Chen; Shaofen Huang; Rui Xie; Jianqi Chen; Wei Liu; Zhiwei Wang; Ruiyu Luo; Jinan Zhan; Yehong Zhuo; Yiqing Li; Yingting Zhu
TAGS: ganglia, macaca fascicularis, retinal nerve fiber layer, cercopithecidae, nose
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):14. https://doi.org/10.1167/iovs.65.11.14

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

The Influence of Femtosecond Laser Intrastromal Lenticules on the Characteristics and Maturity in Engineered RPE Sheets Derived from iPSCs

Jianing Gu; Zhanyu Su; Yini Wang; Yuexi Chen; Chengcheng Ding; Shibo Tang; Jiansu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5379.

ARVO Annual Meeting Abstract June 2024

Aberrant RP patient hiPSCs-derived RPE cells and base editing for repair

Xihao Sun; Yuqin Liang; Duan Chunwen; Shengru Mao; Jiansu Chen; Shibo Tang; Zekai Cui

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1577.

ARVO Annual Meeting Abstract June 2024

Retinal organoids with X-linked Retinoschisis RS1 (E72K) mutation exhibit photoreceptor developmental delay and are rescued by gene augmentation therapy

Duan Chunwen; Chengcheng Ding; Xihao Sun; Shengru Mao; Jiansu Chen; Shibo Tang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1547.

ARVO Annual Meeting Abstract June 2024

Targeting HSP: Tr1 Cell-Mediated Immune Tolerance to HSP60 Attenuates Neurodegeneration in Glaucoma

Shuhong Jiang; Kin-Sang Cho; Eric F. Thee; Irvin Yi; Laila Carmen Prendergast; Ajay Ashok; Julie Chen; Li Pan; Maximilian Braun; Wai Lydia Tai; Sarita Pooranawattanakul; Kasim Gunes; Martine J Jager; Lucy Q Shen; Jianzhu Chen; Dongfeng Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):936.

ARVO Annual Meeting Abstract June 2024

Identification of Lipocalin in Tree Shrew Tears via Top-down Proteomics

Jianzhong Chen; Mustapha El Hamdaoui; Rafael Grytz; Gordon W Laurie

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5752.

ARVO Annual Meeting Abstract June 2024

COL10A1 May be a Novel Factor for the Development of Choroidal Neovascularization

Shibo Tang; Da Lv; Jiansu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5002.

ARVO Annual Meeting Abstract June 2024

Molecular defects of X-linked retinoschisis in RS1-KI (R102W) mouse model

Shengru Mao; Zekai Cui; Xihao Sun; Duan Chunwen; Jiansu Chen; Shibo Tang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6204.

ARVO Annual Meeting Abstract June 2024

Pharmacological characterization and safety of the Nintedanib IVT XR ocular implant

Florian Andreas Colbatzky Andreas Colbatzky; Paul Ashton; Holger Fuchs; Hong Guo; Jianbing Chen; Remko Bakker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6111.

ARVO Annual Meeting Abstract June 2024

Macular retina-targeting AAV capsid identified through multi-species screening in mice, rabbits, pigs, and monkeys

Shengjiang (Shawn) Liu; Haifeng Chen; Sameera Peraramelli; Ningguang Luo; Xiangqun Chen; Jinzhong Li; Xiaoming Gong; Eduardo Santillan; Derrick Huynh; Shuyi Li; Ying Li; Kevin Lin; Minghua Dai; Jianwu Chen; Aggie Yu; Li Ou

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5323.

ARVO Annual Meeting Abstract June 2024

Research of Usher Syndrome with USH2A Mutation Through Microfluidic Retinal Organoids-on-a-Chip

Jiansu Chen; Yonglong Guo; Zekai Cui; Yunxia Xue; Shibo Tang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4537.

ARVO Annual Meeting Abstract June 2024

CRISPR-Cas9 correction of the PRPF6 c.2699G>A variant in retinitis pigmentosa patient-derived iPSCs rescues photoreceptor loss in retinal organoids

Yuqin Liang; Xihao Sun; Duan Chunwen; Zekai Cui; Shengru Mao; Shibo Tang; Jiansu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3823.

ARVO Annual Meeting Abstract June 2024

3D-printed PDMS Microwell Platform Promotes the Stemness of Human Keratocyte Spheroids from SMILE-Derived Lenticules

Yuexi Chen; Jianing Gu; Xihao Sun; Zekai Cui; Yuqin Liang; Jiansu Chen; Zheng Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):519.

ARVO Annual Meeting Abstract June 2024

Investigating the Impact of Stromal Stiffness on Keratoconus Pathogenesis Through a Tunable Extracellular Matrix Model

Xiaoxue Li; Yuqin Liang; Xihao Sun; Jiansu Chen; Zekai Cui

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2046.

ARVO Annual Meeting Abstract June 2024

In Vitro Co-Culture Model Mimicking Diabetic Keratopathy: Integration of Corneal Epithelium, Nerves, Stroma, and Endothelium

Zekai Cui; Xiaoxue Li; Jianing Gu; Shibo Tang; Jiansu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4481.

Artificial Intelligence April 2024

Quantitative Assessment of Fundus Tessellated Density in Highly Myopic Glaucoma Using Deep Learning

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Xiaohong Chen; Xuhao Chen; Jianqi Chen; Zhidong Li; Shaofen Huang; Xinyue Shen; Yue Xiao; Zhenquan Wu; Yingting Zhu; Lin Lu; Yehong Zhuo
TAGS: deep learning, frontotemporal dementia, glaucoma, myopia
Trans. Vis. Sci. Tech.. 2024; 13(4):17. https://doi.org/10.1167/tvst.13.4.17

Includes: Supplemental Content

Immunology and Microbiology January 2024

Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular Degeneration

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Yan-Shan Liu; Jia-Qi Pan; Xu-Bin Pan; Fan-Sheng Kong; Jing-Qian Zhang; Zhi-Yuan Wei; Zhou-Heng Xu; Jun-Hua Rao; Ji-Hong Wang; Jian-Huan Chen
TAGS: age-related macular degeneration, choroidal neovascularization, genes, inflammation, mice, retinitis, multiomics, lasers, rna-seq, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):13. https://doi.org/10.1167/iovs.65.1.13

Includes: Supplemental Content

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Associations Between Diabetic Retinopathy and Frailty: Insights From the National Health and Nutrition Examination Survey and Mendelian Randomization

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

Midperipheral Microvascular Defects and Their Associations With Vitreoretinal Abnormalities in Early-Stage Familial Exudative Vitreoretinopathy

Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Parameters and Their Associated Factors in Cynomolgus Macaques

The Influence of Femtosecond Laser Intrastromal Lenticules on the Characteristics and Maturity in Engineered RPE Sheets Derived from iPSCs

Aberrant RP patient hiPSCs-derived RPE cells and base editing for repair

Retinal organoids with X-linked Retinoschisis RS1 (E72K) mutation exhibit photoreceptor developmental delay and are rescued by gene augmentation therapy

Targeting HSP: Tr1 Cell-Mediated Immune Tolerance to HSP60 Attenuates Neurodegeneration in Glaucoma

Identification of Lipocalin in Tree Shrew Tears via Top-down Proteomics

COL10A1 May be a Novel Factor for the Development of Choroidal Neovascularization

Molecular defects of X-linked retinoschisis in RS1-KI (R102W) mouse model

Pharmacological characterization and safety of the Nintedanib IVT XR ocular implant

Macular retina-targeting AAV capsid identified through multi-species screening in mice, rabbits, pigs, and monkeys

Research of Usher Syndrome with USH2A Mutation Through Microfluidic Retinal Organoids-on-a-Chip

CRISPR-Cas9 correction of the PRPF6 c.2699G>A variant in retinitis pigmentosa patient-derived iPSCs rescues photoreceptor loss in retinal organoids

3D-printed PDMS Microwell Platform Promotes the Stemness of Human Keratocyte Spheroids from SMILE-Derived Lenticules

Investigating the Impact of Stromal Stiffness on Keratoconus Pathogenesis Through a Tunable Extracellular Matrix Model

In Vitro Co-Culture Model Mimicking Diabetic Keratopathy: Integration of Corneal Epithelium, Nerves, Stroma, and Endothelium

Quantitative Assessment of Fundus Tessellated Density in Highly Myopic Glaucoma Using Deep Learning

Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular Degeneration

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