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Retina December 2024

Clinical and Imaging Characteristics of PRPH2 Retinopathies in a Longitudinal Cohort and Diagnostic Implications

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Johanna M. Seddon; Dikha De; Laura Grunenkovaite; Daniela Ferrara
TAGS: cohort studies, diagnostic imaging, genetic pedigree, genetics, phenotype, retinal diseases, visual acuity, atrophoderma maculatum, genes, heterozygote
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):31. https://doi.org/10.1167/iovs.65.14.31

ARVO Annual Meeting Abstract June 2024

The Role of Nutritional Factors in Transitioning between Early, Mid and Late Stages of Age-Related Macular Degeneration

Dikha De; Bernard Rosner; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1348.

ARVO Annual Meeting Abstract June 2024

Genetic and pharmacological reduction of S6K1 alleviates pathologies in the mouse model of age-related macular degeneration (AMD)

Shun-Yun cheng; Dimas Echeverria; Delaney Giguere; Julia Alterman; Martin-Paul Gameli Agbaga; Johanna M Seddon; Anastasia Khvorova; Claudio Punzo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6519.

ARVO Annual Meeting Abstract June 2023

Family History of Age-related Macular Degeneration (AMD) and Genetic Variants Predict Progression to Advanced AMD, Adjusting for Baseline Macular Status, Demographic and Lifestyle Predictors

Johanna M Seddon; Dikha De; Bernard Rosner

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2768.

Articles June 2022

A Screening Tool for Self-Evaluation of Risk for Age-Related Macular Degeneration: Validation in a Spanish Population

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Alfredo García-Layana; Maribel López-Gálvez; José García-Arumí; Luis Arias; Alfredo Gea-Sánchez; Juan J. Marín-Méndez; Onintza Sayar-Beristain; Germán Sedano-Gil; Tariq M. Aslam; Angelo M. Minnella; Isabel López Ibáñez; José M. de Dios Hernández; Johanna M. Seddon
TAGS: age-related macular degeneration, questionnaires, screening, self assessment, spanish, risk factors, ophthalmologists
Trans. Vis. Sci. Tech.. 2022; 11(6):23. https://doi.org/10.1167/tvst.11.6.23

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Ensemble learning for AMD prediction using retina OCT scans

Mousa Moradi; Tianxiao Huan; Yu Chen; Xian Du; Johanna Seddon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):732 – F0460.

ARVO Annual Meeting Abstract June 2022

Identifying Key Drivers Regulating the Metabolites Network of Age-related Macular Degeneration

Tianxiao Huan; Mark Daly; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1184 – A0038.

ARVO Annual Meeting Abstract June 2022

Association between Dysfunctional Complement Factor I ( CFI ) Rare Variant Status and Progression to Advanced AMD

Johanna M Seddon; Bernard Rosner; Anuja Java; John Atkinson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):380 – F0211.

ARVO Annual Meeting Abstract June 2021

Characterizing trans Regulatory Networks of Human Plasma Proteomics in Relation to Age-related Macular Degeneration

Zhongfa Yang; Tianxiao Huan; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1568.

ARVO Annual Meeting Abstract June 2021

Prediction of AMD Progression Within Eye-Specific Baseline Severity Scales, and Attributable Fraction for Modifiable Factors and a Genetic Risk Score

Rafael Widjajahakim; Bernard Rosner; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):325.

ARVO Annual Meeting Abstract June 2021

Automated diagnosis and grading of dry age-related macular degeneration using optical coherence tomography imaging

Mohamed Elsharkawy; Ahmed Sharafeldeen; Ahmed Soliman; Fahmi Khalifa; Rafael Widjajahakim; Andy Switala; Ahmed Elnakib; Shlomit Schaal; Harpal Singh Sandhu; Johanna M Seddon; Ayman El-Baz

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):107.

ARVO Annual Meeting Abstract June 2021

Identifying Genetic Variants in Immune Pathways for Age-related Macular Degeneration

Tianxiao Huan; Rafael Widjajahakim; Zhongfa Yang; John Atkinson; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1494.

ARVO Annual Meeting Abstract June 2021

Comprehensive Analysis of Genetic Variants of Uncertain Significance in Complement Factor I (CFI) in Advanced Age Related Macular Degeneration (AAMD)

Anuja Java; Rafael Widjajahakim; John Atkinson; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):257.

Retina December 2020

Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration

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Johanna M. Seddon; Rafael Widjajahakim; Bernard Rosner

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):32. https://doi.org/10.1167/iovs.61.14.32

Includes: Supplemental Content

Articles August 2020

Functional Analysis of Rare Genetic Variants in Complement Factor I ( CFI ) using a Serum-Based Assay in Advanced Age-related Macular Degeneration

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Anuja Java; Peter Baciu; Rafael Widjajahakim; Yun Ju Sung; Jae Yang; David Kavanagh; John Atkinson; Johanna Seddon
TAGS: age-related macular degeneration, complement factor i, cultural formulation interview, fibrinogen, genetics, inactivated c3b
Trans. Vis. Sci. Tech.. 2020; 9(9):37. https://doi.org/10.1167/tvst.9.9.37

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Registry and Natural History Study to Evaluate Clinical Non-Central Geographic Atrophy (GA) Who are CarRIers of High-Risk GeneTic Variants Associated with Age-Related Macular Degeneration (CLARITY): Study Outline and Available Baseline Data

William Bridges; Nancy Holekamp; Stephen Couvillion; Raj Maturi; Jared S Nielsen; Dante Joseph Pieramici; Glenn J Jaffe; KD Nguyen; Renta Hutabarat; Stephen Eckert; Richard MacKenna; Kiran Patki; Alia Rashid; Johanna M Seddon; Sandra Rojas-Caro

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1043.

ARVO Annual Meeting Abstract June 2020

Rare and Common Genetic Variants and Behavioral Modifiable Factors Are Associated with Earlier Age of Progression to Advanced AMD

Rafael Widjajahakim; Bernard Rosner; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2436.

ARVO Annual Meeting Abstract June 2020

Genetic Susceptibility, Diet Quality and Two Step Progression in Drusen Size

Johanna M Seddon; Bernard Rosner; Benedicte MJ Merle

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2997.

ARVO Annual Meeting Abstract June 2020

Functional Analysis of Genetic Variants in Complement Factor I in Advanced Age-related Macular Degeneration using a Serum-based Assay

Anuja Java; Peter Baciu; David Kavanagh; John Atkinson; Johanna M Seddon

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3651.

Retina May 2020

Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size

PDF

Bénédicte M. J. Merle; Bernard Rosner; Johanna M. Seddon
TAGS: diet, drusen, genetic predisposition to disease, genetics
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):17. https://doi.org/10.1167/iovs.61.5.17

Includes: Supplemental Content

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Clinical and Imaging Characteristics of PRPH2 Retinopathies in a Longitudinal Cohort and Diagnostic Implications

The Role of Nutritional Factors in Transitioning between Early, Mid and Late Stages of Age-Related Macular Degeneration

Genetic and pharmacological reduction of S6K1 alleviates pathologies in the mouse model of age-related macular degeneration (AMD)

Family History of Age-related Macular Degeneration (AMD) and Genetic Variants Predict Progression to Advanced AMD, Adjusting for Baseline Macular Status, Demographic and Lifestyle Predictors

A Screening Tool for Self-Evaluation of Risk for Age-Related Macular Degeneration: Validation in a Spanish Population

Ensemble learning for AMD prediction using retina OCT scans

Identifying Key Drivers Regulating the Metabolites Network of Age-related Macular Degeneration

Association between Dysfunctional Complement Factor I ( CFI ) Rare Variant Status and Progression to Advanced AMD

Characterizing trans Regulatory Networks of Human Plasma Proteomics in Relation to Age-related Macular Degeneration

Prediction of AMD Progression Within Eye-Specific Baseline Severity Scales, and Attributable Fraction for Modifiable Factors and a Genetic Risk Score

Automated diagnosis and grading of dry age-related macular degeneration using optical coherence tomography imaging

Identifying Genetic Variants in Immune Pathways for Age-related Macular Degeneration

Comprehensive Analysis of Genetic Variants of Uncertain Significance in Complement Factor I (CFI) in Advanced Age Related Macular Degeneration (AAMD)

Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration

Functional Analysis of Rare Genetic Variants in Complement Factor I ( CFI ) using a Serum-Based Assay in Advanced Age-related Macular Degeneration

Registry and Natural History Study to Evaluate Clinical Non-Central Geographic Atrophy (GA) Who are CarRIers of High-Risk GeneTic Variants Associated with Age-Related Macular Degeneration (CLARITY): Study Outline and Available Baseline Data

Rare and Common Genetic Variants and Behavioral Modifiable Factors Are Associated with Earlier Age of Progression to Advanced AMD

Genetic Susceptibility, Diet Quality and Two Step Progression in Drusen Size

Functional Analysis of Genetic Variants in Complement Factor I in Advanced Age-related Macular Degeneration using a Serum-based Assay

Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size

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